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The Total Synthesis Of Spirastrellolide A Methyl Ester
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Book Synopsis The Total Synthesis of (+)-spirastrellolide A Methyl Ester by : Philip James Maltas
Download or read book The Total Synthesis of (+)-spirastrellolide A Methyl Ester written by Philip James Maltas and published by . This book was released on 2011 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Total Synthesis of Spirastrellolide A Methyl Ester by : Jong Ho Lim
Download or read book Total Synthesis of Spirastrellolide A Methyl Ester written by Jong Ho Lim and published by . This book was released on 2009 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Studies Toward the Total Synthesis of Spirastrellolide A by : Steven Merwin Kennedy
Download or read book Studies Toward the Total Synthesis of Spirastrellolide A written by Steven Merwin Kennedy and published by . This book was released on 2010 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chapter one of this dissertation describes background into the biological properties of spirastrellolide A (SA) as a potent and selective protein phosphatase inhibitor. It then goes on to provide information on the isolation, structural elucidation, and structural features of SA. Additionally, it compares SA to other natural products with similar biological activity. Finally, chapter one ends with a literature review of synthetic work on SA and the other known spirastrellolides. By highlighting the total syntheses of spirastrellolide A methyl ester by Paterson and spirastrellolide F methyl ester by Fürstner an overview of synthetic challenges, strategies, and methods is seen. Other synthetic progress on the spirastrellolides is also briefly acknowledged. Chapter two provides a detailed account of my spirastrellolide A synthetic progress. It begins by analyzing synthetic challenges inherent to SA. Then my hypothesized synthetic plan for a total synthesis of SA is outlined. Synthetic advancement toward specific fragments of the SA carbon chain is discussed. It covers strategies employed for building the carbon framework of the molecule while installing necessary stereocenters. As chapter two continues, studies toward the synthesis of four distinct fragments of SA are explored. A synthesis of the C41-C47 side chain is explained. The C33-C40 fragment synthesis is also described. Next, the synthesis of stereospecific chlorohydrin containing molecules is examined. Finally, the progress toward a synthesis of the C1-C16 fragment is described in detail. The synthesis of this fragment focuses partially on the incorporation of methodology previously developed in the Chamberlin laboratory to install a cis-tetrahydropyran ring and an anti-1,3-diol moiety. The chapter concludes with suggested work. Chapter three provides all of the necessary information and data to repeat the work reported in chapter two. It begins with experimental procedures for synthesizing each of the key intermediates mentioned in successful synthetic routes. Each experimental procedure is followed by experimental data. Finally, chapter three is followed by an appendix with 1H and 13C NMR spectra useful for identifying key molecular structures.
Book Synopsis The Total Synthesis of Thailandamide A Methyl Ester by : Diane Jennifer Beylkin
Download or read book The Total Synthesis of Thailandamide A Methyl Ester written by Diane Jennifer Beylkin and published by . This book was released on 2015 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Heterocycles in Natural Product Synthesis by : Krishna C. Majumdar
Download or read book Heterocycles in Natural Product Synthesis written by Krishna C. Majumdar and published by John Wiley & Sons. This book was released on 2011-06-15 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt: Filling a gap on the market, this handbook and ready reference is unique in its discussion of the usefulness of various heterocyclic systems in the synthesis of natural products. Clearly structured for easy access to the information, each chapter is devoted to a certain class of heterocycle, providing a tabular presentation of the natural products to be covered containing the particular heterocyclic ring system along with their biological profile, occurrence and most important physical properties, backed by the appropriate references. In addition, the application of the heterocyclic system to the synthesis of natural products ic covered in detail. Of great interest to organic, natural products, medicinal and biochemists, as well as those working in the pharmaceutical and agrochemical industry.
Book Synopsis Total Synthesis of (+)-7,8-epoxy-2-basmen-6-one and (+ -)- Pentalenolactone P Methyl Ester by : Ho-Jung Kang
Download or read book Total Synthesis of (+)-7,8-epoxy-2-basmen-6-one and (+ -)- Pentalenolactone P Methyl Ester written by Ho-Jung Kang and published by . This book was released on 1991 with total page 662 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Naturally Occurring Organohalogen Compounds by : A. Douglas Kinghorn
Download or read book Naturally Occurring Organohalogen Compounds written by A. Douglas Kinghorn and published by Springer Nature. This book was released on 2023-07-24 with total page 553 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present volume is the third in a trilogy that documents naturally occurring organohalogen compounds, bringing the total number — from fewer than 25 in 1968 — to approximately 8,000 compounds to date. Nearly all of these natural products contain chlorine or bromine, with a few containing iodine and, fewer still, fluorine. Produced by ubiquitous marine (algae, sponges, corals, bryozoa, nudibranchs, fungi, bacteria) and terrestrial organisms (plants, fungi, bacteria, insects, higher animals) and universal abiotic processes (volcanos, forest fires, geothermal events), organohalogens pervade the global ecosystem. Newly identified extraterrestrial sources are also documented. In addition to chemical structures, biological activity, biohalogenation, biodegradation, natural function, and future outlook are presented.
Book Synopsis Studies Towards the Total Synthesis of (+)-spirastrellolide A. by : Julien Genovino
Download or read book Studies Towards the Total Synthesis of (+)-spirastrellolide A. written by Julien Genovino and published by . This book was released on 2010 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Au-Catalyzed Synthesis and Functionalization of Heterocycles by : Marco Bandini
Download or read book Au-Catalyzed Synthesis and Functionalization of Heterocycles written by Marco Bandini and published by Springer. This book was released on 2016-07-01 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: The series Topics in Heterocyclic Chemistry presents critical reviews on present and future trends in the research of heterocyclic compounds. Overall the scope is to cover topics dealing with all areas within heterocyclic chemistry, both experimental and theoretical, of interest to the general heterocyclic chemistry community. The series consists of topic related volumes edited by renowned editors with contributions of experts in the field. All chapters from Topics in Heterocyclic Chemistry are published Online First with an individual DOI. In references, Topics in Heterocyclic Chemistry is abbreviated as Top Heterocycl Chem and cited as a journal
Book Synopsis Boron Science by : Narayan S. Hosmane
Download or read book Boron Science written by Narayan S. Hosmane and published by CRC Press. This book was released on 2016-04-19 with total page 856 pages. Available in PDF, EPUB and Kindle. Book excerpt: Boron has made a significant impact in our lives through its quiet use in fertilizers, fungicides, soaps, detergents, and heat-resistant glassware. Boron Science: New Technologies and Applications addresses the applications of boron in chemistry, industry, medicine, and pharmacology by explaining its role in problems such as catalysis and hydrobora
Book Synopsis Modern Alkyne Chemistry by : Barry M. Trost
Download or read book Modern Alkyne Chemistry written by Barry M. Trost and published by John Wiley & Sons. This book was released on 2015-02-09 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive and up-to-date overview of alkyne chemistry, taking into account the progress made over the last two decades. The experienced editors are renowned world leaders in the field, while the list of contributors reads like a "Who's Who" of synthetic organic chemistry. The result is a valuable reference not only for organic chemists at universities and in the chemical industry, but also for biologists and material scientists involved in the modern synthesis of organic compounds and materials.
Book Synopsis Synthesis of Heterocycles by Metathesis Reactions by : Joëlle Prunet
Download or read book Synthesis of Heterocycles by Metathesis Reactions written by Joëlle Prunet and published by Springer. This book was released on 2016-11-26 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: The series Topics in Heterocyclic Chemistry presents critical reviews on present and future trends in the research of heterocyclic compounds. Overall the scope is to cover topics dealing with all areas within heterocyclic chemistry, both experimental and theoretical, of interest to the general heterocyclic chemistry community. The series consists of topic related volumes edited by renowned editors with contributions of experts in the field. All chapters from Topics in Heterocyclic Chemistry are published Online First with an individual DOI. In references, Topics in Heterocyclic Chemistry is abbreviated as Top Heterocycl Chem and cited as a journal.
Book Synopsis Total Synthesis of the Macrolide Core of (+)-spirastrellolide A. by : S. M. Dalby
Download or read book Total Synthesis of the Macrolide Core of (+)-spirastrellolide A. written by S. M. Dalby and published by . This book was released on 2007 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Progress in Heterocyclic Chemistry by : Gordon Gribble
Download or read book Progress in Heterocyclic Chemistry written by Gordon Gribble and published by Elsevier. This book was released on 2010-10-01 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: Progress in Heterocyclic Chemistry (PHC) is an annual review series commissioned by the International Society of Heterocyclic Chemistry (ISHC). Volumes in the series contain both highlights of the previous year's literature on heterocyclic chemistry and articles on emerging topics of particular interest to heterocyclic chemists. The chapters in Volume 22 constitute a systematic survey of the important original material reported in the literature of heterocyclic chemistry in 2009. * Covers the heterocyclic literature published in 2009 * Includes specialized reviews * Features contributions from leading researchers in their fields
Book Synopsis Bridging of Macrocycles to Bicyclic and Oxopolycyclic Ethers by : Brian Edward Marron
Download or read book Bridging of Macrocycles to Bicyclic and Oxopolycyclic Ethers written by Brian Edward Marron and published by . This book was released on 1989 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Approaches to the Total Synthesis of Tetracycline by : John Robert Wiseman
Download or read book Approaches to the Total Synthesis of Tetracycline written by John Robert Wiseman and published by . This book was released on 1964 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: