Numerical Methods and Advanced Simulation in Biomechanics and Biological Processes

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Publisher : Academic Press
ISBN 13 : 0128117192
Total Pages : 462 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Numerical Methods and Advanced Simulation in Biomechanics and Biological Processes by : Miguel Cerrolaza

Download or read book Numerical Methods and Advanced Simulation in Biomechanics and Biological Processes written by Miguel Cerrolaza and published by Academic Press. This book was released on 2017-12-28 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: Numerical Methods and Advanced Simulation in Biomechanics and Biological Processes covers new and exciting modeling methods to help bioengineers tackle problems for which the Finite Element Method is not appropriate. The book covers a wide range of important subjects in the field of numerical methods applied to biomechanics, including bone biomechanics, tissue and cell mechanics, 3D printing, computer assisted surgery and fluid dynamics. Modeling strategies, technology and approaches are continuously evolving as the knowledge of biological processes increases. Both theory and applications are covered, making this an ideal book for researchers, students and R&D professionals. Provides non-conventional analysis methods for modeling Covers the Discrete Element Method (DEM), Particle Methods (PM), MessLess and MeshFree Methods (MLMF), Agent-Based Methods (ABM), Lattice-Boltzmann Methods (LBM) and Boundary Integral Methods (BIM) Includes contributions from several world renowned experts in their fields Compares pros and cons of each method to help you decide which method is most applicable to solving specific problems

Biological Modeling and Simulation

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Publisher : MIT Press
ISBN 13 : 0262303396
Total Pages : 403 pages
Book Rating : 4.2/5 (623 download)

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Book Synopsis Biological Modeling and Simulation by : Russell Schwartz

Download or read book Biological Modeling and Simulation written by Russell Schwartz and published by MIT Press. This book was released on 2008-07-25 with total page 403 pages. Available in PDF, EPUB and Kindle. Book excerpt: A practice-oriented survey of techniques for computational modeling and simulation suitable for a broad range of biological problems. There are many excellent computational biology resources now available for learning about methods that have been developed to address specific biological systems, but comparatively little attention has been paid to training aspiring computational biologists to handle new and unanticipated problems. This text is intended to fill that gap by teaching students how to reason about developing formal mathematical models of biological systems that are amenable to computational analysis. It collects in one place a selection of broadly useful models, algorithms, and theoretical analysis tools normally found scattered among many other disciplines. It thereby gives the aspiring student a bag of tricks that will serve him or her well in modeling problems drawn from numerous subfields of biology. These techniques are taught from the perspective of what the practitioner needs to know to use them effectively, supplemented with references for further reading on more advanced use of each method covered. The text, which grew out of a class taught at Carnegie Mellon University, covers models for optimization, simulation and sampling, and parameter tuning. These topics provide a general framework for learning how to formulate mathematical models of biological systems, what techniques are available to work with these models, and how to fit the models to particular systems. Their application is illustrated by many examples drawn from a variety of biological disciplines and several extended case studies that show how the methods described have been applied to real problems in biology.

Modeling of Microscale Transport in Biological Processes

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Publisher : Academic Press
ISBN 13 : 9780128045954
Total Pages : 0 pages
Book Rating : 4.0/5 (459 download)

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Book Synopsis Modeling of Microscale Transport in Biological Processes by : Sid M. Becker

Download or read book Modeling of Microscale Transport in Biological Processes written by Sid M. Becker and published by Academic Press. This book was released on 2017-01-12 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modeling of Microscale Transport in Biological Processes provides a compendium of recent advances in theoretical and computational modeling of biotransport phenomena at the microscale. The simulation strategies presented range from molecular to continuum models and consider both numerical and exact solution method approaches to coupled systems of equations. The biological processes covered in this book include digestion, molecular transport, microbial swimming, cilia mediated flow, microscale heat transfer, micro-vascular flow, vesicle dynamics, transport through bio-films and bio-membranes, and microscale growth dynamics. The book is written for an advanced academic research audience in the fields of engineering (encompassing biomedical, chemical, biological, mechanical, and electrical), biology and mathematics. Although written for, and by, expert researchers, each chapter provides a strong introductory section to ensure accessibility to readers at all levels.

'In Silico' Simulation of Biological Processes

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Publisher : John Wiley & Sons
ISBN 13 : 0470857900
Total Pages : 270 pages
Book Rating : 4.4/5 (78 download)

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Book Synopsis 'In Silico' Simulation of Biological Processes by : Gregory R. Bock

Download or read book 'In Silico' Simulation of Biological Processes written by Gregory R. Bock and published by John Wiley & Sons. This book was released on 2003-07-07 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over recent decades vast amounts of biological data have been accumulated. However, it is becoming increasingly difficult to apply traditional theoretical methods to the formulation of coherent pictures of cell and organ function because it is no longer possible for a human theorist to integrate all of the available information. Instead, computer technologies must now be used to perform this integration. This book brings together contributions from many different fields to summarize the current status of computer-assisted modelling of biological processes. The initial chapters deal with fundamental developments in hardware, software and mathematics that underlie current approaches to biological modelling. Next, different approaches to collating data on gene structure and function are presented. These databases form a vital resource for any investigator trying to construct an integrated picture of particular biological systems. Cell signalling systems form a particularly complicated aspect of all cellular function and are important both in the understanding of basic cellular processes and in selecting targets for drugs. Recent approaches to integrating data on cell signalling into computer models are covered. Further chapters build on these approaches to show how computerized models of intact cells can be developed. Finally, approaches to the computer modelling of whole organs such as the heart are presented. The role of computer modelling in drug design is the subject of the final chapter and is also touched on throughout the discussions.

Simulation of Biological Processes by Analog and Digital Computers

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Publisher :
ISBN 13 :
Total Pages : 120 pages
Book Rating : 4.:/5 (175 download)

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Book Synopsis Simulation of Biological Processes by Analog and Digital Computers by : Liang-tseng Fan

Download or read book Simulation of Biological Processes by Analog and Digital Computers written by Liang-tseng Fan and published by . This book was released on 1970 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Modeling and Simulation of Biological Processes

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Publisher :
ISBN 13 : 9789736208652
Total Pages : 99 pages
Book Rating : 4.2/5 (86 download)

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Book Synopsis Modeling and Simulation of Biological Processes by :

Download or read book Modeling and Simulation of Biological Processes written by and published by . This book was released on 2011 with total page 99 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Mathematical Modeling of Biological Processes

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Publisher : Springer
ISBN 13 : 3319083147
Total Pages : 152 pages
Book Rating : 4.3/5 (19 download)

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Book Synopsis Mathematical Modeling of Biological Processes by : Avner Friedman

Download or read book Mathematical Modeling of Biological Processes written by Avner Friedman and published by Springer. This book was released on 2014-09-19 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book on mathematical modeling of biological processes includes a wide selection of biological topics that demonstrate the power of mathematics and computational codes in setting up biological processes with a rigorous and predictive framework. Topics include: enzyme dynamics, spread of disease, harvesting bacteria, competition among live species, neuronal oscillations, transport of neurofilaments in axon, cancer and cancer therapy, and granulomas. Complete with a description of the biological background and biological question that requires the use of mathematics, this book is developed for graduate students and advanced undergraduate students with only basic knowledge of ordinary differential equations and partial differential equations; background in biology is not required. Students will gain knowledge on how to program with MATLAB without previous programming experience and how to use codes in order to test biological hypothesis.

The Simulation of Biological Processes

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Publisher :
ISBN 13 :
Total Pages : 488 pages
Book Rating : 4.:/5 (251 download)

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Book Synopsis The Simulation of Biological Processes by : Donald Clem Young

Download or read book The Simulation of Biological Processes written by Donald Clem Young and published by . This book was released on 1962 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Computational Modeling of Biological Systems

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Publisher : Springer Science & Business Media
ISBN 13 : 1461421454
Total Pages : 360 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Computational Modeling of Biological Systems by : Nikolay V Dokholyan

Download or read book Computational Modeling of Biological Systems written by Nikolay V Dokholyan and published by Springer Science & Business Media. This book was released on 2012-02-12 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational modeling is emerging as a powerful new approach to study and manipulate biological systems. Multiple methods have been developed to model, visualize, and rationally alter systems at various length scales, starting from molecular modeling and design at atomic resolution to cellular pathways modeling and analysis. Higher time and length scale processes, such as molecular evolution, have also greatly benefited from new breeds of computational approaches. This book provides an overview of the established computational methods used for modeling biologically and medically relevant systems.

Systems Biology

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Publisher :
ISBN 13 : 9783030730345
Total Pages : 0 pages
Book Rating : 4.7/5 (33 download)

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Book Synopsis Systems Biology by : Jinzhi Lei

Download or read book Systems Biology written by Jinzhi Lei and published by . This book was released on 2021 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses the mathematical simulation of biological systems, with a focus on the modeling of gene expression, gene regulatory networks and stem cell regeneration. The diffusion of morphogens is addressed by introducing various reaction-diffusion equations based on different hypotheses concerning the process of morphogen gradient formation. The robustness of steady-state gradients is also covered through boundary value problems. The introduction gives an overview of the relevant biological concepts (cells, DNA, organism development) and provides the requisite mathematical preliminaries on continuous dynamics and stochastic modeling. A basic understanding of calculus is assumed. The techniques described in this book encompass a wide range of mechanisms, from molecular behavior to population dynamics, and the inclusion of recent developments in the literature together with first-hand results make it an ideal reference for both new students and experienced researchers in the field of systems biology and applied mathematics.

Modeling Biological Systems:

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Publisher : Springer Science & Business Media
ISBN 13 : 9780387250113
Total Pages : 500 pages
Book Rating : 4.2/5 (51 download)

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Book Synopsis Modeling Biological Systems: by : James W. Haefner

Download or read book Modeling Biological Systems: written by James W. Haefner and published by Springer Science & Business Media. This book was released on 2005-05-06 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: I Principles 1 1 Models of Systems 3 1. 1 Systems. Models. and Modeling . . . . . . . . . . . . . . . . . . . . 3 1. 2 Uses of Scientific Models . . . . . . . . . . . . . . . . . . . . . . . . 4 1. 3 Example: Island Biogeography . . . . . . . . . . . . . . . . . . . . . 6 1. 4 Classifications of Models . . . . . . . . . . . . . . . . . . . . . . . . 10 1. 5 Constraints on Model Structure . . . . . . . . . . . . . . . . . . . . . 12 1. 6 Some Terminology . . . . . . . . . . . . . . . . . . . . . . . . . . . 12 1. 7 Misuses of Models: The Dark Side . . . . . . . . . . . . . . . . . . . 13 1. 8 Exercises . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15 2 The Modeling Process 17 2. 1 Models Are Problems . . . . . . . . . . . . . . . . . . . . . . . . . . 17 2. 2 Two Alternative Approaches . . . . . . . . . . . . . . . . . . . . . . 18 2. 3 An Example: Population Doubling Time . . . . . . . . . . . . . . . . 24 2. 4 Model Objectives . . . . . . . . . . . . . . . . . . . . . . . . . . . . 28 2. 5 Exercises . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30 3 Qualitative Model Formulation 32 3. 1 How to Eat an Elephant . . . . . . . . . . . . . . . . . . . . . . . . . 32 3. 2 Forrester Diagrams . . . . . . . . . . . . . . . . . . . . . . . . . . . 33 3. 3 Examples . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 36 3. 4 Errors in Forrester Diagrams . . . . . . . . . . . . . . . . . . . . . . 44 3. 5 Advantages and Disadvantages of Forrester Diagrams . . . . . . . . . 44 3. 6 Principles of Qualitative Formulation . . . . . . . . . . . . . . . . . . 45 3. 7 Model Simplification . . . . . . . . . . . . . . . . . . . . . . . . . . 47 3. 8 Other Modeling Problems . . . . . . . . . . . . . . . . . . . . . . . . 49 viii Contents . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3. 9 Exercises 53 4 Quantitative Model Formulation: I 4. 1 From Qualitative to Quantitative . . . . . . . . . . . . . . . . . Finite Difference Equations and Differential Equations 4. 2 . . . . . . . . . . . . . . . . 4. 3 Biological Feedback in Quantitative Models . . . . . . . . . . . . . . . . . . . . . . . . . . 4. 4 Example Model . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4. 5 Exercises 5 Quantitative Model Formulation: I1 81 . . . . . . . . . . . . . . . . . . . . . . . . . . . 5. 1 Physical Processes 81 . . . . . . . . . . . . . . . 5. 2 Using the Toolbox of Biological Processes 89 . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5. 3 Useful Functions 96 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5. 4 Examples 102 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5. 5 Exercises 104 6 Numerical Techniques 107 . . . . . . . . . . . . . . . . . . . . . . . 6. 1 Mistakes Computers Make 107 . . . . . . . . . . . . . . . . . . . . . . . . . . 6. 2 Numerical Integration 110 . . . . . . . . . . . . . . . . 6. 3 Numerical Instability and Stiff Equations 115 . . . . . . . . . . . . . .

Tutorial for Modeling and Simulation of Biological Processes

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Publisher :
ISBN 13 : 9788001044919
Total Pages : 145 pages
Book Rating : 4.0/5 (449 download)

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Book Synopsis Tutorial for Modeling and Simulation of Biological Processes by : Michel Kana

Download or read book Tutorial for Modeling and Simulation of Biological Processes written by Michel Kana and published by . This book was released on 2010 with total page 145 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Computer Simulation and Data Analysis in Molecular Biology and Biophysics

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Publisher : Springer Science & Business Media
ISBN 13 : 1441900837
Total Pages : 325 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Computer Simulation and Data Analysis in Molecular Biology and Biophysics by : Victor Bloomfield

Download or read book Computer Simulation and Data Analysis in Molecular Biology and Biophysics written by Victor Bloomfield and published by Springer Science & Business Media. This book was released on 2009-06-05 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an introduction to two important aspects of modern bioch- istry, molecular biology, and biophysics: computer simulation and data analysis. My aim is to introduce the tools that will enable students to learn and use some f- damental methods to construct quantitative models of biological mechanisms, both deterministicandwithsomeelementsofrandomness;tolearnhowconceptsofpr- ability can help to understand important features of DNA sequences; and to apply a useful set of statistical methods to analysis of experimental data. The availability of very capable but inexpensive personal computers and software makes it possible to do such work at a much higher level, but in a much easier way, than ever before. TheExecutiveSummaryofthein?uential2003reportfromtheNationalAcademy of Sciences, “BIO 2010: Transforming Undergraduate Education for Future - search Biologists” [12], begins The interplay of the recombinant DNA, instrumentation, and digital revolutions has p- foundly transformed biological research. The con?uence of these three innovations has led to important discoveries, such as the mapping of the human genome. How biologists design, perform, and analyze experiments is changing swiftly. Biological concepts and models are becoming more quantitative, and biological research has become critically dependent on concepts and methods drawn from other scienti?c disciplines. The connections between the biological sciences and the physical sciences, mathematics, and computer science are rapidly becoming deeper and more extensive.

Modelling and Simulation of Biological Processes in the Context of Genomics

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Publisher :
ISBN 13 :
Total Pages : 293 pages
Book Rating : 4.:/5 (592 download)

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Book Synopsis Modelling and Simulation of Biological Processes in the Context of Genomics by : Philippe Tracqui

Download or read book Modelling and Simulation of Biological Processes in the Context of Genomics written by Philippe Tracqui and published by . This book was released on 2002 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Heat Transfer and Fluid Flow in Biological Processes

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Publisher : Academic Press
ISBN 13 : 0124079008
Total Pages : 428 pages
Book Rating : 4.1/5 (24 download)

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Book Synopsis Heat Transfer and Fluid Flow in Biological Processes by : Sid M. Becker

Download or read book Heat Transfer and Fluid Flow in Biological Processes written by Sid M. Becker and published by Academic Press. This book was released on 2014-12-31 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heat Transfer and Fluid Flow in Biological Processes covers emerging areas in fluid flow and heat transfer relevant to biosystems and medical technology. This book uses an interdisciplinary approach to provide a comprehensive prospective on biofluid mechanics and heat transfer advances and includes reviews of the most recent methods in modeling of flows in biological media, such as CFD. Written by internationally recognized researchers in the field, each chapter provides a strong introductory section that is useful to both readers currently in the field and readers interested in learning more about these areas. Heat Transfer and Fluid Flow in Biological Processes is an indispensable reference for professors, graduate students, professionals, and clinical researchers in the fields of biology, biomedical engineering, chemistry and medicine working on applications of fluid flow, heat transfer, and transport phenomena in biomedical technology. Provides a wide range of biological and clinical applications of fluid flow and heat transfer in biomedical technology Covers topics such as electrokinetic transport, electroporation of cells and tissue dialysis, inert solute transport (insulin), thermal ablation of cancerous tissue, respiratory therapies, and associated medical technologies Reviews the most recent advances in modeling techniques

Modeling of Microscale Transport in Biological Processes

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Publisher : Academic Press
ISBN 13 : 0128046198
Total Pages : 396 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Modeling of Microscale Transport in Biological Processes by : Sid M. Becker

Download or read book Modeling of Microscale Transport in Biological Processes written by Sid M. Becker and published by Academic Press. This book was released on 2016-12-27 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modeling of Microscale Transport in Biological Processes provides a compendium of recent advances in theoretical and computational modeling of biotransport phenomena at the microscale. The simulation strategies presented range from molecular to continuum models and consider both numerical and exact solution method approaches to coupled systems of equations. The biological processes covered in this book include digestion, molecular transport, microbial swimming, cilia mediated flow, microscale heat transfer, micro-vascular flow, vesicle dynamics, transport through bio-films and bio-membranes, and microscale growth dynamics. The book is written for an advanced academic research audience in the fields of engineering (encompassing biomedical, chemical, biological, mechanical, and electrical), biology and mathematics. Although written for, and by, expert researchers, each chapter provides a strong introductory section to ensure accessibility to readers at all levels. Features recent developments in theoretical and computational modeling for clinical researchers and engineers Furthers researcher understanding of fluid flow in biological media and focuses on biofluidics at the microscale Includes chapters expertly authored by internationally recognized authorities in the fundamental and applied fields that are associated with microscale transport in living media

Cybernetic Modeling for Bioreaction Engineering

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Publisher : Cambridge University Press
ISBN 13 : 1107000521
Total Pages : 295 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Cybernetic Modeling for Bioreaction Engineering by : Doraiswami Ramkrishna

Download or read book Cybernetic Modeling for Bioreaction Engineering written by Doraiswami Ramkrishna and published by Cambridge University Press. This book was released on 2018-10-18 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: Describes dynamic state of metabolic systems, while paving the way for fully predictive modeling frameworks.