The Secret Lives Of Transcription Factors

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The Secret Lives of Transcription Factors

Author : Willis X. Li
Publisher : Springer Nature
ISBN 13 : 3031290291
Total Pages : 62 pages
Book Rating : 4.0/5 (312 download)

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Book Synopsis The Secret Lives of Transcription Factors by : Willis X. Li

Download or read book The Secret Lives of Transcription Factors written by Willis X. Li and published by Springer Nature. This book was released on 2023-04-25 with total page 62 pages. Available in PDF, EPUB and Kindle. Book excerpt: This SpringerBrief explores unconventional functions of eight different transcription factors and concludes with a discussion of their biological significance and impact, including effects on processes within the cell nucleaus during development and in adult organisms. Chapter One details unconventional functions of the transcription factors GAGA, HP1, Rb, STAT, ATF-2 and NF-kB. Surprisingly, all of these transcription factors can be found in association with heterochromatin as well as euchromatin, and in some cases unconventional functions have been demonstrated for these heterochromatin-associated factors. Chapter Two focuses on the unconventional functions of STAT and HP1 and discusses their roles in the promotion of longevity, and in protection from cancer and DNA damage. Chapter Three explores the biological significance of the findings presented in the first two chapters and considers how global changes in the epigenome brought about by factors such as STAT and HP1 might affect processes within the cell nucleus during development and in adult organisms. This succinct yet thorough SpringerBrief is essential for researchers studying epigenetics, and to instructors of the subject. It should also appeal to people interested in the control of gene transcription and other processes in the cell nucleus, and to those interested in development.

How We Live and Why We Die: The Secret Lives of Cells

Author : Lewis Wolpert
Publisher : W. W. Norton & Company
ISBN 13 : 039329272X
Total Pages : 256 pages
Book Rating : 4.3/5 (932 download)

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Book Synopsis How We Live and Why We Die: The Secret Lives of Cells by : Lewis Wolpert

Download or read book How We Live and Why We Die: The Secret Lives of Cells written by Lewis Wolpert and published by W. W. Norton & Company. This book was released on 2011-01-24 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Acclaimed biologist Lewis Wolpert eloquently narrates the basics of human life through the lens of its smallest component: the cell. Everything about our existence-movement and memory, imagination and reproduction, birth, and ultimately death-is governed by our cells. They are the basis of all life in the universe, from bacteria to the most complex animals. In the tradition of the classic Lives of a Cell, but with the benefit of the latest research, Lewis Wolpert demonstrates how human life grows from a single cell into a body, an incredibly complex society of billions of cells. Wolpert goes on to examine the science behind topics that are much discussed but rarely understood—stem-cell research, cloning, DNA, cancer—and explains how all life on earth evolved from just one cell. Lively and passionate, this is an accessible guide to understanding the human body and life itself.

Heme Biology

Author :
Publisher :
ISBN 13 : 9814466573
Total Pages : pages
Book Rating : 4.8/5 (144 download)

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Book Synopsis Heme Biology by :

Download or read book Heme Biology written by and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Forkhead Transcription Factors

Author : Kenneth Maiese
Publisher : Springer Science & Business Media
ISBN 13 : 1441915990
Total Pages : 283 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Forkhead Transcription Factors by : Kenneth Maiese

Download or read book Forkhead Transcription Factors written by Kenneth Maiese and published by Springer Science & Business Media. This book was released on 2010-07-29 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: Forkhead Transcription Factors: Vital Elements in Biology and Medicine provides a unique platform for the presentation of novel work and new insights into the vital role that forkhead transcription factors play in multiple systems throughout the body. Leading international authorities provide their knowledge and insights to offer a novel perspective for translational medicine that highlights the role of forkhead genes and proteins that may have the greatest impact for the development of new strategies for a broad array of disorders. Equally important, Forkhead Transcription Factors: Vital Elements in Biology and Medicine clearly sets a precedent for the necessity to understand the diverse and complex nature of forkhead proteins since this family of transcription factors can limit as well as foster disease progression depending upon the cellular environment. The presentation and discussion of innovative studies and especially those that examine previously unexplored pathways that may influence clinical survival and longevity offer an exciting approach to address the potential of forkhead transcription factors for new therapeutic avenues in multiple disciplines.

Seed to Seed

Author : Nicholas Harberd
Publisher : Bloomsbury Publishing USA
ISBN 13 : 1582344132
Total Pages : 324 pages
Book Rating : 4.5/5 (823 download)

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Book Synopsis Seed to Seed by : Nicholas Harberd

Download or read book Seed to Seed written by Nicholas Harberd and published by Bloomsbury Publishing USA. This book was released on 2006-05-01 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: Part field notebook, part sketchbook, and part diary, relates these observational narratives to the life history of an 'iconic' plant, giving a description of what is 'seen' and of the hidden molecular mechanisms that underlie the visible events in the pl

Genomics of Plant-Associated Fungi and Oomycetes: Dicot Pathogens

Author : Ralph A. Dean
Publisher : Springer
ISBN 13 : 3662440563
Total Pages : 244 pages
Book Rating : 4.6/5 (624 download)

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Book Synopsis Genomics of Plant-Associated Fungi and Oomycetes: Dicot Pathogens by : Ralph A. Dean

Download or read book Genomics of Plant-Associated Fungi and Oomycetes: Dicot Pathogens written by Ralph A. Dean and published by Springer. This book was released on 2014-08-22 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes how genomics has revolutionized our understanding of agriculturally important plant-associated fungi and oomycetes. It illustrates some fundamental discoveries about these eukaryotic microbes with regard to the overall structure of their genomes, their lifestyles and the molecular mechanisms that form the basis of their interactions with plants. Genomics has provided new insights into fungal lifestyles and led to practical advances in plant breeding and crop protection, such as predictions about the spread and evolution of new pathogens. This volume focuses on fungi and oomycetes that are typical dicot plant pathogens and includes: Sclerotinia sclerotiorum, Botrytis cinerea, Alternaria sp.,Verticillium alfalfae and Verticillium dahliae, Fusarium oxysporum, Phytophthora capsici, Phytophthora sojae, Phytophthora ramorum, Phytophthora infestans, Hyaloperonospora arabidopsidis.

Understanding Tuberculosis

Author : Pere-Joan Cardona
Publisher : BoD – Books on Demand
ISBN 13 : 9533079460
Total Pages : 348 pages
Book Rating : 4.5/5 (33 download)

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Book Synopsis Understanding Tuberculosis by : Pere-Joan Cardona

Download or read book Understanding Tuberculosis written by Pere-Joan Cardona and published by BoD – Books on Demand. This book was released on 2012-02-17 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mycobacterium tuberculosis, as recent investigations demonstrate, has a complex signaling expression, which allows its close interaction with the environment and one of its most renowned properties: the ability to persist for long periods of time under a non-replicative status. Although this skill is well characterized in other bacteria, the intrinsically very slow growth rate of Mycobium tuberculosis, together with a very thick and complex cell wall, makes this pathogen specially adapted to the stress that could be generated by the host against them. In this book, different aspects of these properties are displayed by specialists in the field.

Impact of Early Life Nutrition on Immune System Development and Related Health Outcomes in Later Life

Author : Laxmi Yeruva
Publisher : Frontiers Media SA
ISBN 13 : 2889668134
Total Pages : 208 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Impact of Early Life Nutrition on Immune System Development and Related Health Outcomes in Later Life by : Laxmi Yeruva

Download or read book Impact of Early Life Nutrition on Immune System Development and Related Health Outcomes in Later Life written by Laxmi Yeruva and published by Frontiers Media SA. This book was released on 2021-05-28 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Immunology and Allergy Clinics, An Issue of Immunology and Allergy Clinics of North America , E-Book

Author : Mark Ballow
Publisher : Elsevier Health Sciences
ISBN 13 : 032376004X
Total Pages : 169 pages
Book Rating : 4.3/5 (237 download)

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Book Synopsis Immunology and Allergy Clinics, An Issue of Immunology and Allergy Clinics of North America , E-Book by : Mark Ballow

Download or read book Immunology and Allergy Clinics, An Issue of Immunology and Allergy Clinics of North America , E-Book written by Mark Ballow and published by Elsevier Health Sciences. This book was released on 2020-08-04 with total page 169 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Immunology and Allergy Clinics, guest edited by Dr. Mark Ballow and Dr. Elena Perez, will provide up-to-date clinical concepts regarding Immunodeficiencies. Articles in this outstanding issue include: Precision Medicine for Patients with Primary Immune Dysregulation, Immune Disorders Associated with Abnormalities in Treg Cells, Defining Common Variable Immunodeficiency, The Importance of Primary Immune Deficiency Registries, Chronic Lung Disease in Primary Antibody Deficiency: Diagnosis and Management, Immune Deficiencies Associated with Th17 Immunity, Truths and Myths of Vaccines in Patients with Primary Immune Deficiency, The Nuts and Bolts of Subcutaneous Immunoglobulin Replacement Therapy, Newly Discovered Primary Immune Deficiencies, and Specific Antibody Deficiency.

Mitochondrial Neuropathies

Author :
Publisher : Academic Press
ISBN 13 : 0128172258
Total Pages : 252 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Mitochondrial Neuropathies by :

Download or read book Mitochondrial Neuropathies written by and published by Academic Press. This book was released on 2019-06-15 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mitochondrial Neuropathies, Volume 146, brings together experts in a range of diseases that damage the nervous system to present the role of mitochondrial dysfunction in their particular field, with this new release focusing on Mitochondrial dysfunction in Alzheimer's Disease, HIV and the mitochondrial: immune interface in the CNS, The Impact of mitochondrial damage in HIV-induced peripheral neuropathy, Mitochondrial dysfunction and the pathogenesis of chemotherapy-induced peripheral neuropathy, Disorders of mitochondrial biogenesis in peripheral neuropathy, Mitochondrial dysfunction and the pathogenesis of diabetic neuropathy, Manipulating mitochondria to treat peripheral neuropathy, and DCA therapy - the yin and yang of mitochondrial activation. Contains contributions from a diverse group of experts Presents a timely resource that brings together different fields to highlight a common pathogenic mechanism Focuses on the role of mitochondria in diverse neuropathies

Flavonoids and Anti-Aging

Author : Karam F.A. Soliman
Publisher : CRC Press
ISBN 13 : 1000835200
Total Pages : 293 pages
Book Rating : 4.0/5 (8 download)

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Book Synopsis Flavonoids and Anti-Aging by : Karam F.A. Soliman

Download or read book Flavonoids and Anti-Aging written by Karam F.A. Soliman and published by CRC Press. This book was released on 2023-05-03 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: The nuclear factor erythroid 2-related factor 2 (Nrf2) was described as a master regulator of the cellular antioxidant response. Moreover, many critical biological functions linked to cell viability, metabolism, autophagy, inflammation, immunity, and differentiation have been attributed to Nrf2, which regulates over 600 genes. It is well known that oxidative stress, which Nrf2 can ameliorate, plays a key role in many pathologic processes such as aging, obesity, diabetes, cancer, and neurodegenerative diseases. Flavonoids, on the other hand, through their ability to activate and upregulate Nrf2, can have anti-oxidative, anti-inflammatory, anti-mutagenic, and anti-carcinogenic properties. Flavonoids are an essential ingredient in nutraceuticals, functional foods, and pharmaceuticals. The present book Flavonoids and Anti-Aging: The Role of Transcription Factor Nuclear Erythroid 2-Related Factor2 focuses on the interaction between Nrf2 and flavonoids and their applications in various conditions such as aging, osteoporosis, cardiovascular diseases, and neurodegenerative disease and many other areas. Key Features: Focuses on the mechanisms and use of flavonoids in activating Nrf2 as an anti-aging and "WELLNESS" molecule Provides a specific approach to flavonoid activation of Nrf2 and its implications in aging and various disease conditions and its applications as nutraceuticals Presents flavonoid-based functional foods Discusses the flavonoid nutraceuticals market and future trends Written by experts in the field, this book provides a unique approach to understanding the flavonoid activation of the transcription factor Nrf2, which is responsible for many different disease conditions due to increased reactive oxidative species in the body caused by some physiological triggers.

Index Medicus

Author :
Publisher :
ISBN 13 :
Total Pages : 2036 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Index Medicus by :

Download or read book Index Medicus written by and published by . This book was released on 2004 with total page 2036 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.

The Scientific Basis of Urology

Author : Anthony R. Mundy
Publisher : CRC Press
ISBN 13 : 1841847496
Total Pages : 602 pages
Book Rating : 4.8/5 (418 download)

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Book Synopsis The Scientific Basis of Urology by : Anthony R. Mundy

Download or read book The Scientific Basis of Urology written by Anthony R. Mundy and published by CRC Press. This book was released on 2010-07-26 with total page 602 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written specifically for urological trainees by a distinguished team of contributors, this third edition of The Scientific Basis of Urology provides the reader with a thorough coverage of urology. Every area, function, illness and treatment of the urinary tract, along with specific discussions of the relevant anatomy and physiology, is included in clearly written text, abundantly illustrated with full color photographs and diagrams. Each chapter takes the basic principles of its topic area and expands upon them to ensure maximum understanding.

Epistemology of the Cell

Author : Edward R. Dougherty
Publisher : John Wiley & Sons
ISBN 13 : 1118104870
Total Pages : 204 pages
Book Rating : 4.1/5 (181 download)

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Book Synopsis Epistemology of the Cell by : Edward R. Dougherty

Download or read book Epistemology of the Cell written by Edward R. Dougherty and published by John Wiley & Sons. This book was released on 2011-08-17 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Honorable mention – Biomedicine and Neuroscience, 2011 Prose Awards" An examination of how the cell should be described in order to effectively process biological data "The fruitful pursuit of biological knowledge requires one to take Einstein's admonition [on science without epistemology] as a practical demand for scientific research, to recognize Waddington's characterization of the subject matter of biology, and to embrace Wiener's conception of the form of biological knowledge in response to its subject matter. It is from this vantage point that we consider the epistemology of the cell." —from the Preface In the era of high biological data throughput, biomedical engineers need a more systematic knowledge of the cell in order to perform more effective data handling. Epistemology of the Cell is the first authored book to break down this knowledge. This text examines the place of biological knowledge within the framework of science as a whole and addresses issues focused on the specific nature of biology, how biology is studied, and how biological knowledge is translated into applications, in particular with regard to medicine. The book opens with a general discussion of the historical development of human understanding of scientific knowledge, the scientific method, and the manner in which scientific knowledge is represented in mathematics. The narrative then gets specific for biology, focusing on knowledge of the cell, the basic unit of life. The salient point is the analogy between a systems-based analysis of factory regulation and the regulation of the cell. Each chapter represents a key topic of current interest, including: Causality and randomness Translational science Stochastic validation: classification Stochastic validation: networks Model-based experimentation in biology Epistemology of the Cell is written for biomedical researchers whose interests include bioinformatics, biological modeling, biostatistics, and biological signal processing.

Advances in Virus Research

Author :
Publisher : Elsevier
ISBN 13 : 0443295131
Total Pages : 282 pages
Book Rating : 4.4/5 (432 download)

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Book Synopsis Advances in Virus Research by :

Download or read book Advances in Virus Research written by and published by Elsevier. This book was released on 2024-03-01 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Virus Research, Volume 118 highlights new advances in the field, with this new volume presenting interesting chapters on topics such as HCMV-encoded GPCRs in infection, disease, and pathogenesis, Defense signaling pathways in resistance to plant viruses: crosstalk and finger pointing, and Pathogenesis of neuroinvasive flaviviruses. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in Advances in Virus Research series

Pharmacoepigenetics

Author :
Publisher : Academic Press
ISBN 13 : 0128139404
Total Pages : 983 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Pharmacoepigenetics by :

Download or read book Pharmacoepigenetics written by and published by Academic Press. This book was released on 2019-06-04 with total page 983 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmacoepigenetics, Volume Eleven provides a comprehensive volume on the role of epigenetics and epigenomics in drug discovery and development, providing a detailed, but accessible, view of the field, from basic principles, to applications in disease therapeutics. Leading international researchers from across academia, clinical settings and the pharmaceutical industry discuss the influence of epigenetics and epigenomics in human pathology, epigenetic biomarkers for disease prediction, diagnosis, and treatment, current epigenetic drugs, and the application of epigenetic procedures in drug development. Throughout the book, chapter authors offer a balanced and objective discussion of the future of pharmacoepigenetics and its crucial contribution to the growth of precision and personalized medicine. Fully examines the influence of epigenetics and epigenomics in human pathology, epigenetic biomarkers for disease prediction, diagnosis, treatment, current epigenetic drugs and the application of epigenetic procedures in drug development Features chapter contributions from leading international researchers in academia, clinical settings and the pharmaceutical industry Instructs researchers, students and clinicians on how to better interpret and employ pharmacoepigenetics in drug development, efficiency and safety Provides a balanced and objective discussion of the future of pharmacoepigenetics and its crucial role in precision medicine

Basal Cell Carcinoma

Author : Vishal Madan
Publisher : BoD – Books on Demand
ISBN 13 : 9535103091
Total Pages : 138 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Basal Cell Carcinoma by : Vishal Madan

Download or read book Basal Cell Carcinoma written by Vishal Madan and published by BoD – Books on Demand. This book was released on 2012-03-14 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: Basal cell carcinoma is the commonest cutaneous malignancy. The last decade has witnessed exponential research which has broadened our understanding of the pathogenesis of basal cell carcinomas. This is also important from a therapeutic point of view as targeted approach to therapy is now being increasingly experimented. Although it is impossible to condense and present all good research in one book, the authors have to be commended on presenting their research on several aspects of basal cell carcinoma in a succinct manner, which shall not only enhance our understanding of, but also hopefully via this open exchange of ideas pave ways for successful targeted therapy of the commonest human cancer.