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Author : Graham C. Boorse
Publisher :
ISBN 13 :
Total Pages : 500 pages
Book Rating : 4.3/5 (91 download)
Download or read book The Roles of the Corticotropin-releasing Factor System in Amphibians written by Graham C. Boorse and published by . This book was released on 2004 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher : Academic Press
ISBN 13 : 008088783X
Total Pages : 5944 pages
Book Rating : 4.0/5 (88 download)
Download or read book Hormones, Brain and Behavior Online written by and published by Academic Press. This book was released on 2002-06-18 with total page 5944 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hormones, Brain, and Behavior, Second Edition is a comprehensive work discussing the effect of hormones on the brain and, subsequently, behavior. This major reference work has 109 chapters covering a broad range of topics with an extensive discussion of the effects of hormones on insects, fish, amphibians, birds, rodents, and humans. To truly understand all aspects of our behavior, we must take every influence (including the hormonal influences) into consideration. Donald Pfaff and a number of well-qualified editors examine and discuss how we are influenced by hormonal factors, offering insight, and information on the lives of a variety of species. Hormones, Brain, and Behavior offers the reader comprehensive coverage of growing field of research, with a state-of-the-art overview of hormonally-mediated behaviors. This reference provides unique treatment of all major vertebrate and invertebrate model systems with excellent opportunities for relating behavior to molecular genetics. The topics cover an unusual breadth (from molecules to ecophysiology), ranging from basic science to clinical research, making this reference of interest to a broad range of scientists in a variety of fields. Available online exclusively via ScienceDirect. A limited edition print version is also available. Comprehensive coverage of a growing field of research Unique treatment of all major vertebrate and invertebrate model systems with excellent opportunites for relating behavior to molecular genetics Covers an unusual breadth ranging from molecules to ecophysiology, and from basic science to clinical research
Author : OECD
Publisher : OECD Publishing
ISBN 13 : 9264076247
Total Pages : 33 pages
Book Rating : 4.2/5 (64 download)
Download or read book OECD Guidelines for the Testing of Chemicals, Section 2 Test No. 231: Amphibian Metamorphosis Assay written by OECD and published by OECD Publishing. This book was released on 2009-09-08 with total page 33 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline describes an amphibian metamorphosis assay intended to screen substances which may interfere with the normal functioning of the hypothalamo-pituitary-thyroid axis. The assay was validated with the species Xenopus laevis, which is ...
Author : Ruben Vardanyan
Publisher : Academic Press
ISBN 13 : 0124115241
Total Pages : 868 pages
Book Rating : 4.1/5 (241 download)
Download or read book Synthesis of Best-Seller Drugs written by Ruben Vardanyan and published by Academic Press. This book was released on 2016-01-07 with total page 868 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthesis of Best-Seller Drugs is a key reference guide for all those involved with the design, development, and use of the best-selling drugs. Designed for ease of use, this book provides detailed information on the most popular drugs, using a practical layout arranged according to drug type. Each chapter reviews the main drugs in each of nearly 40 key therapeutic areas, also examining their classification, novel structural features, models of action, and synthesis. Of high interest to all those who work in the captivating areas of biologically active compounds and medicinal drug synthesis, in particular medicinal chemists, biochemists, and pharmacologists, the book aims to support current research efforts, while also encouraging future developments in this important field. Describes methods of synthesis, bioactivity and related drugs in key therapeutic areas Reviews the main drugs in each of nearly 40 key therapeutic areas, also examining their classification, novel structural features, models of action, and more Presents a practical layout designed for use as a quick reference tool by those working in drug design, development and implementation
Author : Elena Choleris
Publisher : Cambridge University Press
ISBN 13 : 1107328055
Total Pages : 409 pages
Book Rating : 4.1/5 (73 download)
Download or read book Oxytocin, Vasopressin and Related Peptides in the Regulation of Behavior written by Elena Choleris and published by Cambridge University Press. This book was released on 2013-04-11 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt: The mammalian neurohypophyseal peptide hormones oxytocin and vasopressin act to mediate human social behavior - they affect trust and social relationships and have an influence on avoidance responses. Describing the evolutionary roots of the effects that these neuropeptides have on behavior, this book examines remarkable parallel findings in both humans and non-human animals. The chapters are structured around three key issues: the molecular and neurohormonal mechanisms of peptides; phylogenetic considerations of their role in vertebrates; and their related effects on human behavior, social cognition and clinical applications involving psychiatric disorders such as autism. A final chapter summarizes current research perspectives and reflects on the outlook for future developments. Providing a comparative overview and featuring contributions from leading researchers, this is a valuable resource for graduate students, researchers and clinicians in this rapidly developing field.
Author : Andrzej T. Slominski
Publisher : Springer Science & Business Media
ISBN 13 : 3642196837
Total Pages : 128 pages
Book Rating : 4.6/5 (421 download)
Download or read book Sensing the Environment: Regulation of Local and Global Homeostasis by the Skin's Neuroendocrine System written by Andrzej T. Slominski and published by Springer Science & Business Media. This book was released on 2012-06-02 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: The skin, the body’s largest organ, is strategically located at the interface with the external environment where it detects, integrates and responds to a diverse range of stressors, including solar radiation. It has already been established that the skin is an important peripheral neuroendocrine-immune organ that is closely networked with central regulatory systems. These capabilities contribute to the maintenance of peripheral homeostasis. Specifically, epidermal and dermal cells produce and respond to classical stress neurotransmitters, neuropeptides and hormones, production which is stimulated by ultraviolet radiation (UVR), biological factors (infectious and non-infectious) and other physical and chemical agents. Examples of local biologically active products are cytokines, biogenic amines (catecholamines, histamine, serotonin and N-acetyl-serotonin), melatonin, acetylocholine, neuropeptides including pituitary (proopiomelanocortin-derived ACTH, b-endorphin or MSH peptides, thyroid stimulating hormone) and hypothalamic (corticotropin-releasing factor and related urocortins, thyroid-releasing hormone) hormones, as well as enkephalins and dynorphins, thyroid hormones, steroids (glucocorticoids, mineralocorticoids, sex hormones, 7-δ steroids), secosteroids, opioids and endocannabinoids. The production of these molecules is hierarchical, organized along the algorithms of classical neuroendocrine axes such as the hypothalamic pituitary adrenal axis (HPA), hypothalamic-thyroid axis (HPT), serotoninergic, melatoninergic, catecholaminergic, cholinergic, steroid/secosteroidogenic, opioid and endocannabinoid systems. Disruptions of these axes or of communication between them may lead to skin and/or systemic diseases. These local neuroendocrine networks also serve to limit the effect of noxious environmental agents to preserve local and consequently global homeostasis. Moreover, the skin-derived factors/systems can also activate cutaneous nerve endings to alert the brain to changes in the epidermal or dermal environments, or alternatively to activate other coordinating centers by direct (spinal cord) neurotransmission without brain involvement. Furthermore, rapid and reciprocal communications between epidermal and dermal and adnexal compartments are also mediated by neurotransmission including antidromic modes of conduction. Lastly, skin cells and the skin as an organ coordinate and/or regulate not only peripheral but also global homeostasis.
Author : Yun-Bo Shi
Publisher : Wiley-Liss
ISBN 13 : 9780471244752
Total Pages : 292 pages
Book Rating : 4.2/5 (447 download)
Download or read book Amphibian Metamorphosis written by Yun-Bo Shi and published by Wiley-Liss. This book was released on 1999-10-18 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: In an age when advanced molecular and genetic tools allow studies in various systems, amphibian metamorphosis still offers perhaps the most accessible model for the study of postembryonic organogenesis and mechanisms of hormonal regulation during vertebrate development. Amphibian Metamorphosis: From Morphology to Molecular Biology integrates findings from the most recent research with earlier observations, providing molecular and mechanistic insights into the signal transduction pathways underlying tissue-specific transformations during metamorphosis. The author, renowned expert of anuran metamorphosis and Head of the Unit of Molecular Morphogenesis at NICHD/NIH, begins with an overview of metamorphosis in different classes of amphibians and various factors that influence this process. A review of earlier morphological, cellular, and biochemical changes focuses on organs and tissues that have been studied extensively at the molecular level, while discussion of the thyroid hormone signal transduction pathway emphasizes transcriptional regulation mechanisms by thyroid receptors. The book provides a summary and comparison of gene regulation programs induced by thyroid hormone in several organs that undergo distinct metamorphic transformations. Several chapters are devoted to functional and mechanistic implications of the molecular findings on the thyroid hormone response genes in tissue transformation. Special features of this book include: * An emphasis on integrating the morphological approach with molecularand cell biology * A historical perspective on the progression from discovery of the thyroid hormone to present-day research advances * Comparisons of amphibian and insect metamorphosis * Dozens of instructive photographs, several in full color Amphibian Metamorphosis: From Morphology to Molecular Biology is a unique and invaluable resource for professionals and aspiring professionals in develop-mental biology, molecular biology, cell biology, evolutionary biology, and endocrinology.
Author : George Fink
Publisher : Academic Press
ISBN 13 : 0123750970
Total Pages : 895 pages
Book Rating : 4.1/5 (237 download)
Download or read book Handbook of Neuroendocrinology written by George Fink and published by Academic Press. This book was released on 2012 with total page 895 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroendocrinology underpins fundamental physiological, molecular, biological, and genetic principles such as the regulation of gene transcription and translation. This handbook highlights the experimental and technical foundations of each area's major concepts and principles.
Author : IMechE
Publisher : Elsevier
ISBN 13 : 0857095056
Total Pages : 676 pages
Book Rating : 4.8/5 (57 download)
Download or read book Vehicle thermal Management Systems Conference and Exhibition (VTMS10) written by IMechE and published by Elsevier. This book was released on 2011-05-05 with total page 676 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains the papers presented at the IMechE and SAE International, Vehicle Thermal Management Systems Conference (VTMS10), held at the Heritage Motor Centre, Gaydon, Warwickshire, 15-19th May 2011. VTMS10 is an international conference organised by the Automobile Division and the Combustion Engines and Fuels Group of the IMechE and SAE International. The event is aimed at anyone involved with vehicle heat transfer, members of the OEM, tier one suppliers, component and software suppliers, consultants, and academics interested in all areas of thermal energy management in vehicles. This vibrant conference, the tenth VTMS, addresses the latest analytical and development tools and techniques, with sessions on: alternative powertrain, emissions, engines, heat exchange/manufacture, heating, A/C, comfort, underhood, and external/internal component flows. It covers the latest in research and technological advances in the field of heat transfer, energy management, comfort and the efficient management of all thermal systems within the vehicle. Aimed at anyone working in or involved with vehicle heat transfer Covers research and technological advances in heat transfer, energy management, comfort and efficient management of thermal systems within the vehicle
Author : Shafiqur Rahman
Publisher : Academic Press
ISBN 13 : 0123855071
Total Pages : 468 pages
Book Rating : 4.1/5 (238 download)
Download or read book The Brain as a Drug Target written by Shafiqur Rahman and published by Academic Press. This book was released on 2011-02-22 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brain is protected by the blood-brain barrier and this barrier prevents many drugs from entering the brain. This volume discusses various drug delivery and targeting strategies that are being developed to enhance the transport and distribution of drugs into the brain. * Discusses new discoveries, approaches, and ideas * Contributions from leading scholars and industry experts * Reference guide for researchers involved in molecular biology and related fields
Author :
Publisher :
ISBN 13 :
Total Pages : 912 pages
Book Rating : 4.:/5 (319 download)
Download or read book Biomedical Index to PHS-supported Research written by and published by . This book was released on 1988 with total page 912 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Marco António Campinho
Publisher : Frontiers Media SA
ISBN 13 : 2889634035
Total Pages : 213 pages
Book Rating : 4.8/5 (896 download)
Download or read book The Role of Thyroid Hormones in Vertebrate Development written by Marco António Campinho and published by Frontiers Media SA. This book was released on 2020-01-24 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : James A. Carr
Publisher : Frontiers Media SA
ISBN 13 : 2889195376
Total Pages : 116 pages
Book Rating : 4.8/5 (891 download)
Download or read book Metabolism and Behavior in the Corticotropin-Releasing Factor Family of Peptides written by James A. Carr and published by Frontiers Media SA. This book was released on 2015-08-03 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nothing provided
Author :
Publisher : Academic Press
ISBN 13 : 0128036087
Total Pages : 2474 pages
Book Rating : 4.1/5 (28 download)
Download or read book Hormones, Brain and Behavior written by and published by Academic Press. This book was released on 2016-11-09 with total page 2474 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hormones, Brain and Behavior, Third Edition offers a state-of-the-art overview of hormonally-mediated behaviors, including an extensive discussion of the effects of hormones on insects, fish, amphibians, birds, rodents, and humans. Entries have been carefully designed to provide a valuable source of information for students and researchers in neuroendocrinology and those working in related areas, such as biology, psychology, psychiatry, and neurology. This third edition has been substantially restructured to include both foundational information and recent developments in the field. Continuing the emphasis on interdisciplinary research and practical applications, the book includes articles aligned in five main subject sections, with new chapters included on genetic and genomic techniques and clinical investigations. This reference provides unique treatment of all major vertebrate and invertebrate model systems with excellent opportunities for relating behavior to molecular genetics. The topics cover an unusual breadth (from molecules to ecophysiology), ranging from basic science to clinical research, making this reference of interest to a broad range of scientists in a variety of fields. Comprehensive and updated coverage of a rapidly growing field of research Unique treatment of all major vertebrate and invertebrate model systems with excellent opportunities for relating behavior to molecular genetics Covers an unusual breadth of topics and subject fields, ranging from molecules to ecophysiology, and from basic science to clinical research Ideal resource for interdisciplinary learning and understanding in the fields of hormones and behavior
Author : Derek J. Chadwick
Publisher : John Wiley & Sons
ISBN 13 : 047051437X
Total Pages : 368 pages
Book Rating : 4.4/5 (75 download)
Download or read book Corticotropin-Releasing Factor written by Derek J. Chadwick and published by John Wiley & Sons. This book was released on 2008-04-30 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Working on Corticotropin-Releasing Factor in a variety of systems, experts present a coherent depiction of this peptide's role in the control and coordination of the response to stress-inducing situations.
Author :
Publisher :
ISBN 13 :
Total Pages : 1796 pages
Book Rating : 4.3/5 (243 download)
Download or read book Cumulated Index Medicus written by and published by . This book was released on 2000 with total page 1796 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Abba Kastin
Publisher : Elsevier
ISBN 13 : 0080463797
Total Pages : 1682 pages
Book Rating : 4.0/5 (84 download)
Download or read book Handbook of Biologically Active Peptides written by Abba Kastin and published by Elsevier. This book was released on 2011-04-28 with total page 1682 pages. Available in PDF, EPUB and Kindle. Book excerpt: Peptides play a crucial role in many physiological processes including actions as neurotransmitters, hormones, and antibiotics. Research has shown their importance in such fields as neuroscience, immunology, pharmacology, and cell biology. The Handbook of Biologically Active Peptides presents, for the first time, this tremendous body of knowledge in the field of biologically active peptides in one single reference. The section editors and contributors represent some of the most sophisticated and distinguished scientists working in basic sciences and clinical medicine. The Handbook of Biologically Active Peptides is a definitive, all-encompassing reference that will be indispensable for individuals ranging from peptide researchers, to biochemists, cell and molecular biologists, neuroscientists, pharmacologists, and to endocrinologists. Chapters are designed to be a source for workers in the field and will enable researchers working in a specific area to examine other related areas with which they would not ordinarily be familiar. *Chapters are designed to be a source for workers in the field and will enable researchers working in a specific area to examine other related areas that they would not ordinarily be familiar.*Fascinating relationships described in the book include the presence of some peptides originally found in frog skin that persist in the human human and brain where they can affect food intake and obesity.
