The Role Of Lymphokines In The Immune Response

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The Role of Lymphokines in the Immune Response

Author : Stanley Cohen
Publisher : CRC Press
ISBN 13 : 9780849364273
Total Pages : 292 pages
Book Rating : 4.3/5 (642 download)

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Book Synopsis The Role of Lymphokines in the Immune Response by : Stanley Cohen

Download or read book The Role of Lymphokines in the Immune Response written by Stanley Cohen and published by CRC Press. This book was released on 1989-12-27 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a broad overview of all aspects of modern lymphokine research. It begins with the ways in which lymphokines play a role in the activation of the immune response and concludes with their participation in various facets of host defense. It devotes special attention to structure, mechanism of action, and range application. In addition, this fascinating work also shows how lymphokines are involved in other physiologic responses, such as reparative reactions involving fibrosis and angiogenesis. This is an excellent resource for students and investigators in the biomedical sciences, as well as clinicians who require up-to-date information about our current understanding of immune processes.

Human Lymphokines

Author : Amanullah Khan
Publisher : Elsevier
ISBN 13 : 0323142672
Total Pages : 756 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis Human Lymphokines by : Amanullah Khan

Download or read book Human Lymphokines written by Amanullah Khan and published by Elsevier. This book was released on 2012-12-02 with total page 756 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human Lymphokines: The Biological Immune Response Modifiers is a collection of papers presented at the Third International Symposium on Human Lymphokines held on October 15-17, 1981 at the Wadley Institutes of Molecular Medicine in Dallas, Texas. Contributors explore the role of human lymphokines in immune responses and their applications in immunotherapy. The focus is on lymphokines that have either entered clinical trials or are nearing clinical evaluation. Some of the activities of possible immediate significance, such as Glia cell stimulating factor and polyclonal B-cell activator, are also described. This volume is organized into six sections encompassing 56 chapters and begins with an overview of assay systems, touching on topics such as the activation of macrophages by interferon to produce plasminogen and macrophage activation by lymphokine factors. The next sections turn to the production, purification, and biological and chemical characterization of lymphokines. The discussion then shifts to the mechanisms of action of lymphokines in vitro and the use of animal models in lymphokine investigations, including lymphokine fractions in a mouse tumor model and enhancement of natural killing activity by different types of interferon. A great deal of emphasis is placed on macrophage migration inhibitory factor, lymphotoxins, gamma interferon, and interleukins. The book concludes with chapters devoted to the immunoregulatory effects of lymphokines and clinical studies.

Biology of the Lymphokines

Author : Stanley Cohen
Publisher : Academic Press
ISBN 13 : 1483271420
Total Pages : 645 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Biology of the Lymphokines by : Stanley Cohen

Download or read book Biology of the Lymphokines written by Stanley Cohen and published by Academic Press. This book was released on 2013-09-17 with total page 645 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biology of the Lymphokines discusses the scope and diversity of lymphokine research. This book focuses on the studies on lymphokines, such as those involving cellular source, chemical nature, purification strategies, and bioassay limitations. The mechanism of lymphokine action, lymphokines in vivo, and value of lymphokine quantitations are also covered. This text describes the repertoire of lymphokines produced by various lymphoblastoid cell lines and its significance for coping with the problem of large scale lymphokine production. The anti-viral and general immunoregulatory properties of interferons and rationale developed for integrating interferons with the family of lymphokines are likewise deliberated. This publication is a good source for students and researchers conducting work on lymphokines.

Immunophysiology

Author : Joost J. Oppenheim
Publisher : Oxford University Press, USA
ISBN 13 :
Total Pages : 456 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Immunophysiology by : Joost J. Oppenheim

Download or read book Immunophysiology written by Joost J. Oppenheim and published by Oxford University Press, USA. This book was released on 1990 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: This exciting new text describes how cells normally regulate immunological and inflammatory reactions, and how the immune system is intimately related to other bodily functions. The authors consider the effects of lymphokines on non-inflammatory cells and tissues, including connective tissue and the neuroendocrine system, and describe the effects of neuroendocrine and peptide growth factors produced by non-inflammatory cells and tissues on the functions of immune cells. To highlight the factors regulating immunophysiological functions, they discuss the inflammatory consequences of endotoxin, immune complexes, and complement; the interactions of immunomodulating epidermal factors and immune tissue; the modulation interactions of immunomodulating epidermal factors and immune tissue; and the modulation of immunity by cytokines. The mechanisms by which the immune system normally contends with bacterial, viral or tumor challenges are examined, with an emphasis on basic concepts and key experimental results; and the cells directly involved in host-defense processes are discussed. Wherever possible, information about in vivo and in vitro human immune responses is presented.

Janeway's Immunobiology

Author : Kenneth Murphy
Publisher : Garland Science
ISBN 13 : 9780815344575
Total Pages : pages
Book Rating : 4.3/5 (445 download)

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Book Synopsis Janeway's Immunobiology by : Kenneth Murphy

Download or read book Janeway's Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

Mediators of the Immune Response

Author : Nikolaĭ Vasilʹevich Medunitsyn
Publisher : Routledge
ISBN 13 :
Total Pages : 348 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Mediators of the Immune Response by : Nikolaĭ Vasilʹevich Medunitsyn

Download or read book Mediators of the Immune Response written by Nikolaĭ Vasilʹevich Medunitsyn and published by Routledge. This book was released on 1987 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Lymphokines

Author : Edgar Pick
Publisher : Elsevier
ISBN 13 : 1483266990
Total Pages : 472 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Lymphokines by : Edgar Pick

Download or read book Lymphokines written by Edgar Pick and published by Elsevier. This book was released on 2014-06-05 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lymphokines: A Forum for Immunoregulatory Cell Products deals with immunoregulatory cell products that produce lymphokines. Topics covered include the purification and characterization of transfer factor; activation of cytotoxicity and/or suppressor activity in murine macrophages by lymphokines, lipopolysaccharide, and polyinosinic-polycytidylic acid; and the role of clotting processes in the action of lymphokines on macrophages. A comparison of the immune-modulating effects of interferon and interferon inducers is also presented. Comprised of 13 chapters, this volume begins with a discussion on transfer factor and its ability to react specifically with antigens. The clinical uses of transfer factor are considered with special emphasis on its value as a prophylactic agent. The reader is then introduced to the subject of T cell regulation of the immunoglobulin E (IgE) response via potentiating and suppressor lymphokines, together with the possible clinical application of IgE suppressive factors in the treatment of atopic diseases. Subsequent chapters examine the evidence in favor of the existence of T cell-derived polyclonal B cell activator (PBA) playing a role in both normal antibody responses and autoimmune diseases; the role of suppressor T cells and the associated lymphokines in contact sensitivity in mice; and lymphokine action on macrophages. The book also analyzes the genetics of the response of human and mouse cells to interferons. This monograph will be helpful to practitioners and researchers in the fields of microbiology and immunology.

Biotechnology and Pharmacy

Author : J.M. Pezzuto
Publisher : Springer Science & Business Media
ISBN 13 : 9401581355
Total Pages : 465 pages
Book Rating : 4.4/5 (15 download)

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Book Synopsis Biotechnology and Pharmacy by : J.M. Pezzuto

Download or read book Biotechnology and Pharmacy written by J.M. Pezzuto and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 465 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biotechnology and Pharmacy offers a unique overview of the principles of biotechnology and their applications in the pharmaceutical sciences. The book assumes a basic knowledge of biology and chemistry and was written as a text suitable for students of pharmacy or other health sciences. The first part of the book describes the basic elements of biotechnology, such as recombinant DNA and monoclonal antibody technology; the second part comprehensively covers applications of biotechnology in the diagnosis and treatment of disease; and the final part offers a practical discussion of how biotechnology products will affect the practice of pharmacy. Microbiologists, biochemists, and medicinal chemists will also find this book to be a valuable reference.

Biologic Markers in Immunotoxicology

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309043891
Total Pages : 225 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Biologic Markers in Immunotoxicology by : National Research Council

Download or read book Biologic Markers in Immunotoxicology written by National Research Council and published by National Academies Press. This book was released on 1992-02-01 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: Are environmental pollutants threatening the human immune system? Researchers are rapidly approaching definitive answers to this question, with the aid of biologic markersâ€"sophisticated assessment tools that could revolutionize detection and prevention of certain diseases. This volume, third in a series on biologic markers, focuses on the human immune system and its response to environmental toxicants. The authoring committee provides direction for continuing development of biologic markers, with strategies for applying markers to immunotoxicology in humans and recommended outlines for clinical and field studies. This comprehensive, up-to-date volume will be invaluable to specialists in toxicology and immunology and to biologists and investigators involved in the development of biologic markers.

Immunology Guidebook

Author : Julius Cruse
Publisher : Elsevier
ISBN 13 : 0080478425
Total Pages : 1000 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Immunology Guidebook by : Julius Cruse

Download or read book Immunology Guidebook written by Julius Cruse and published by Elsevier. This book was released on 2004-08-05 with total page 1000 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Immunology Guidebook provides an easily accessible text-reference to the more up-to-date and difficult concepts in the complex science of immunology. It aims to demystify basic concepts and specialised molecular and cellular interactions. Its 18 chapters offer a logical and sequential presentation where much of the data is displayed in carefully designed tables. This book is intended for immunology students, researchers, practitioners and basic biomedical scientists. Tables provide a quick reference to ‘difficult to find' immunology data A distillate of the latest information on immunogenetics of the human MHC associated with tissue transplantation Information boxes featurw related web resources

The Lymphokines

Author : John W. Hadden
Publisher :
ISBN 13 :
Total Pages : 472 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Lymphokines by : John W. Hadden

Download or read book The Lymphokines written by John W. Hadden and published by . This book was released on 1981-10-31 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Lymphokines and Interleukins

Author : Maureen M. Dawson
Publisher :
ISBN 13 :
Total Pages : 264 pages
Book Rating : 4.:/5 (44 download)

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Book Synopsis Lymphokines and Interleukins by : Maureen M. Dawson

Download or read book Lymphokines and Interleukins written by Maureen M. Dawson and published by . This book was released on 1991 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Clinical Applications of Cytokines

Author : Joost J. Oppenheim
Publisher : Oxford University Press, USA
ISBN 13 : 9780195071290
Total Pages : 406 pages
Book Rating : 4.0/5 (712 download)

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Book Synopsis Clinical Applications of Cytokines by : Joost J. Oppenheim

Download or read book Clinical Applications of Cytokines written by Joost J. Oppenheim and published by Oxford University Press, USA. This book was released on 1993 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: The driving force for research on cytokines has always been their clinical promise. Their biological properties suggested a key role in hematopoiesis, immunity, tumor genesis, hemostasis, vascularization, repair of connective tissues and integration of the immune system with the neuroendocrine system. Animal studies have shown that cytokines could be used as effective biotherapeutics with easily manageable and reversible toxicities. Clinical trials have confirmed these findings, culminating in the licensing of a number of the cytokines such as interferon alpha, interferon gamma, interleukin 2, erythropoietin, granulocyte colony stimulating factor, and granulocyte-macrophage colony stimulating factor. Many other cytokines are in clinical trials. This is the first comprehensive volume on the cytokines written primarily from a medical perspective. After presenting background information about the structure, production, assays and systemic effects of cytokines and their receptors, it is organized around diseases and organ systems. Infectious diseases, autoimmunity, immunodeficiency states, defective hematopoiesis, allergies, injury repair, cancer, vascular and skin diseases, and neurological disorders are all covered. This work reviews the role that cytokines play in the pathogenesis, diagnosis and therapy of each disease. The authors assess both the current state of the art and the potential for future applications.

Military Strategies for Sustainment of Nutrition and Immune Function in the Field

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309173183
Total Pages : 722 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Military Strategies for Sustainment of Nutrition and Immune Function in the Field by : Institute of Medicine

Download or read book Military Strategies for Sustainment of Nutrition and Immune Function in the Field written by Institute of Medicine and published by National Academies Press. This book was released on 1999-05-13 with total page 722 pages. Available in PDF, EPUB and Kindle. Book excerpt: Every aspect of immune function and host defense is dependent upon a proper supply and balance of nutrients. Severe malnutrition can cause significant alteration in immune response, but even subclinical deficits may be associated with an impaired immune response, and an increased risk of infection. Infectious diseases have accounted for more off-duty days during major wars than combat wounds or nonbattle injuries. Combined stressors may reduce the normal ability of soldiers to resist pathogens, increase their susceptibility to biological warfare agents, and reduce the effectiveness of vaccines intended to protect them. There is also a concern with the inappropriate use of dietary supplements. This book, one of a series, examines the impact of various types of stressors and the role of specific dietary nutrients in maintaining immune function of military personnel in the field. It reviews the impact of compromised nutrition status on immune function; the interaction of health, exercise, and stress (both physical and psychological) in immune function; and the role of nutritional supplements and newer biotechnology methods reported to enhance immune function. The first part of the book contains the committee's workshop summary and evaluation of ongoing research by Army scientists on immune status in special forces troops, responses to the Army's questions, conclusions, and recommendations. The rest of the book contains papers contributed by workshop speakers, grouped under such broad topics as an introduction to what is known about immune function, the assessment of immune function, the effect of nutrition, and the relation between the many and varied stresses encountered by military personnel and their effect on health.

Lymphokines

Author : Anne S. Hamblin
Publisher : Oxford University Press, USA
ISBN 13 :
Total Pages : 90 pages
Book Rating : 4.:/5 (44 download)

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Book Synopsis Lymphokines by : Anne S. Hamblin

Download or read book Lymphokines written by Anne S. Hamblin and published by Oxford University Press, USA. This book was released on 1988 with total page 90 pages. Available in PDF, EPUB and Kindle. Book excerpt: The past three years have seen an explosion of knowledge on lymphokines. This textbook focuses on the structures and functions of the newly characterized lymphokines and brings together detailed information from many primary sources.

Lymphokines

Author : Edgar Pick
Publisher :
ISBN 13 : 9780124320147
Total Pages : 496 pages
Book Rating : 4.3/5 (21 download)

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Book Synopsis Lymphokines by : Edgar Pick

Download or read book Lymphokines written by Edgar Pick and published by . This book was released on 1987 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Biologic Markers in Pulmonary Toxicology

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 9780309039925
Total Pages : 198 pages
Book Rating : 4.0/5 (399 download)

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Book Synopsis Biologic Markers in Pulmonary Toxicology by : National Research Council

Download or read book Biologic Markers in Pulmonary Toxicology written by National Research Council and published by National Academies Press. This book was released on 1989-02-01 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biologic markersâ€"indicators of biological exposure or changeâ€"offer the promise of early detection of disease caused by environmental exposure. Researchers have used these markers to discover indications of pulmonary damage from low-level ozone, a finding with serious implications for health professionals and environmental regulators. Biologic Markers in Pulmonary Toxicology is a comprehensive study of this use of biologic markers. Focusing on the respiratory tract as an entryway for airborne pollutants, this volume reviews new ways of measuring markers, the need for markers to indicate dose or exposure levels, noninvasive respiratory function tests for use with healthy humans to detect sensitivity to inhaled pollutants, approaches to evaluating markers down to the cellular and biochemical levels, and more.