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The Role Of Cd44 In Periodontal Ligament Organization And Repair
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Book Synopsis The Role of CD44 in Periodontal Ligament Organization and Repair by : Holly Nicole Hinderberger
Download or read book The Role of CD44 in Periodontal Ligament Organization and Repair written by Holly Nicole Hinderberger and published by . This book was released on 2012 with total page 43 pages. Available in PDF, EPUB and Kindle. Book excerpt: Periodontal ligament development and adaptation is fundamental for the proper function of dentition. The periodontal ligament (PDL) provides structural support for the teeth within the alveolar bone. Derived embryonically from the ectomesenchyme of the dental follicle, the PDL is a complex connective tissue composed of many cells including fibroblasts, macrophages, cementum cells, bone cells, as well as vascular and neural elements. The PDL is capable of high turnover rates as seen in orthodontic tooth movement. CD44, a multifunctional cell surface glycoprotein that is involved in cellular interactions, is thought to play an important role in the cellular organization of the PDL as well as in the migration of reparative cells after PDL injury. The purpose of this study was to determine the significance of CD44 during normal PDL adaptation and during PDL repair in response to orthodontic injury. At 41 days postnatal (dpn) four wild-type and four CD44 knockout mice were sacrificed and prepped for histological analysis. Histological sections were prepared and analyzed using Canvas software. Fibroblast cell angles were measured with respect to the root surface 20 ℗æm below the cementoenamel junction (CEJ). A previous study found a significant difference between the PDL fibroblast angle measurements of CD44 knockout and wild-type mice at day 26 dpn; however, no significant difference was noted at day 41 dpn. This finding suggests that the lost function of CD44 is capable of correcting itself in the CD44 knockout mice, or that there are other receptors found in the PDL, such as RHAMM, that compensate for the function of the CD44 receptor. In order to explore the significance of CD44 in PDL repair after orthodontic tooth movement an orthodontic wire was placed unilaterally on the maxilla of 21 wild-type and five CD44 knockout mice at day 31 dpn. Wires were activated for 5 days before being cut to allow for recovery. Mice were sacrificed at day 41 dpn and prepped for histological analysis. Results of this study are to be determined.
Book Synopsis Dental Stem Cells: Regenerative Potential by : Barbara Zavan
Download or read book Dental Stem Cells: Regenerative Potential written by Barbara Zavan and published by Humana Press. This book was released on 2016-07-25 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on the basic aspects of dental stem cells (DSCs) as well as their clinical applications in tissue engineering and regenerative medicine. It opens with a discussion of classification, protocols, and properties of DSCs and proceeds to explore DSCs within the contexts of cryopreservation; epigenetics; pulp, periodontal, tooth, bone, and corneal stroma regeneration; neuronal properties, mesenchymal stem cells and biomaterials; and as sources of hepatocytes for liver disease treatment. The fifteen expertly authored chapters comprehensively examine possible applications of DSCs and provide invaluable insights into mechanisms of growth and differentiation. Dental Stem Cells: Regenerative Potential draws from a wealth of international perspectives and is an essential addition to the developing literature on dental stem cells. This installment of Springer’s Stem Cell Biology and Regenerative Medicine series is indispensable for biomedical researchers interested in bioengineering, dentistry, tissue engineering, regenerative medicine, cell biology and oncology.
Book Synopsis Biomaterials for Oral and Dental Tissue Engineering by : Lobat Tayebi
Download or read book Biomaterials for Oral and Dental Tissue Engineering written by Lobat Tayebi and published by Woodhead Publishing. This book was released on 2017-07-28 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomaterials for Oral and Dental Tissue Engineering examines the combined impact of materials, advanced techniques and applications of engineered oral tissues. With a strong focus on hard and soft intraoral tissues, the book looks at how biomaterials can be manipulated and engineered to create functional oral tissue for use in restorative dentistry, periodontics, endodontics and prosthodontics. Covering the current knowledge of material production, evaluation, challenges, applications and future trends, this book is a valuable resource for materials scientists and researchers in academia and industry. The first set of chapters reviews a wide range of biomaterial classes for oral tissue engineering. Further topics include material characterization, modification, biocompatibility and biotoxicity. Part Two reviews strategies for biomaterial scaffold design, while chapters in parts three and four review soft and hard tissues. - Connects materials science with restorative dentistry - Focuses on the unique field of intraoral tissues - Highlights long-term biocompatibility and toxicity of biomaterials for engineered oral tissues
Book Synopsis Endodontics by : Mahmoud Torabinejad
Download or read book Endodontics written by Mahmoud Torabinejad and published by Elsevier Health Sciences. This book was released on 2009-01-01 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: This 4th edition is an essential scientific & clinical building block for understanding the etiology & treatment of teeth with pulpal & periapical diseases. You'll easily understand & learn procedures through step-by-step explanations accompanied by illustrations, as well as video clips included on CD.
Book Synopsis The Periodontium by : Hubert E. Schroeder
Download or read book The Periodontium written by Hubert E. Schroeder and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: In their contribution to the first edition of this Handbook, entitled "The Teeth," LEHNER and PLENK (1936) discussed the tissues constituting the "perio dontium" rather briefly. In contrast to the detailed paragraphs dealing with, for example, enamel and dentine, the section (about 40 pages and 20 illustra tions, mostly drawings) devoted to periodontal tissues failed to provide a factual review and summary of the contemporary knowledge and latest developments in research on the various components of the periodontium. Instead, much of the text was an attempt to arrive at conclusions from often purely semantic speculations, playing the various schools of thought against each other, provid ing arguments in favor of the authors' views and arguments for the feasibility and probability of accepting or rejecting the often diverse opinions, while the reader was referred to the already existing literature for factual details. Since 1936, however, factual details ofthe structural biology of the periodon tal tissues, i. e. their development, structure, function, and physiology, have been greatly extended and have been internationally accepted. With much less opin ionated belief to cope with, this knowledge has formed the solid foundation upon which diagnosis, prevention, and treatment in the fields of clinical perio dontology, modem orthodontics, and re- and transplantation procedures of teeth have been built.
Book Synopsis The Periodontal Ligament in Health and Disease by : B. K. B. Berkovitz
Download or read book The Periodontal Ligament in Health and Disease written by B. K. B. Berkovitz and published by . This book was released on 1995 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Stem Cell Biology and Tissue Engineering in Dental Sciences by : Ajaykumar Vishwakarma
Download or read book Stem Cell Biology and Tissue Engineering in Dental Sciences written by Ajaykumar Vishwakarma and published by Academic Press. This book was released on 2014-11-05 with total page 933 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stem Cell Biology and Tissue Engineering in Dental Sciences bridges the gap left by many tissue engineering and stem cell biology titles to highlight the significance of translational research in this field in the medical sciences. It compiles basic developmental biology with keen focus on cell and matrix biology, stem cells with relevance to tissue engineering biomaterials including nanotechnology and current applications in various disciplines of dental sciences; viz., periodontology, endodontics, oral & craniofacial surgery, dental implantology, orthodontics & dentofacial orthopedics, organ engineering and transplant medicine. In addition, it covers research ethics, laws and industrial pitfalls that are of particular importance for the future production of tissue constructs. Tissue Engineering is an interdisciplinary field of biomedical research, which combines life, engineering and materials sciences, to progress the maintenance, repair and replacement of diseased and damaged tissues. This ever-emerging area of research applies an understanding of normal tissue physiology to develop novel biomaterial, acellular and cell-based technologies for clinical and non-clinical applications. As evident in numerous medical disciplines, tissue engineering strategies are now being increasingly developed and evaluated as potential routine therapies for oral and craniofacial tissue repair and regeneration. - Diligently covers all the aspects related to stem cell biology and tissue engineering in dental sciences: basic science, research, clinical application and commercialization - Provides detailed descriptions of new, modern technologies, fabrication techniques employed in the fields of stem cells, biomaterials and tissue engineering research including details of latest advances in nanotechnology - Includes a description of stem cell biology with details focused on oral and craniofacial stem cells and their potential research application throughout medicine - Print book is available and black and white, and the ebook is in full color
Book Synopsis Mechanosensitive Ion Channels by : Andre Kamkin
Download or read book Mechanosensitive Ion Channels written by Andre Kamkin and published by Springer Science & Business Media. This book was released on 2007-10-06 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores the latest data dealing with mechanosensitive channels research results. It was compiled by a group of internationally recognized scientists leading in the field of mechanosensitive ion channels or mechanically gated channels and signaling cascades research. Key problems of cell mechanobiology are also discussed. As a whole, the volume dwells on the major issues of mechanical stress influencing the ion channels and intracellular signaling pathways.
Download or read book Human Tendons written by László G. Józsa and published by Human Kinetics Publishers. This book was released on 1997-01-01 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt: Unquestionably the most comprehensive text on human tendons written by two internationally renowned experts. >Human Tendons> is not only a theoretically based resource for researchers, scientists, and medical specialists, it also is a practical reference for sports medicine practitioners, physicians, and physical therapists.Focusing on the macroscopic and microscopic anatomy, physiology, and pathology of human tendons, the authors present all the available knowledge on the subject in one book. This definitive guide covers these topics on tendons in depth:--Construction, function, metabolism, and biomechanics-Embryonal and postnatal development-Pathologies and anomolies-Effects of physical activity, immobilization, rehabilitation, and aging-History of tenotomy-Injuries, disorders, and diseases-Diagnostic and treatment principles-Healing, transplants, and regenerationThe 386 photographs and 82 illustrations help to bring the content to life.
Book Synopsis The Glaucoma Book by : Paul N. Schacknow
Download or read book The Glaucoma Book written by Paul N. Schacknow and published by Springer Science & Business Media. This book was released on 2010-06-10 with total page 1019 pages. Available in PDF, EPUB and Kindle. Book excerpt: Complete evidence-based medical and surgical management of glaucoma for both the general ophthalmologist in practice and residents The only book that covers the new generation of glaucoma procedures including trabectome, trabecular bypass and canaloplasty, by the experts who developed them Includes the latest laser treatments for glaucoma including micro diode and titanium saphire trabeculoplasty as well as laser from an external approach The most comprehensive coverage of the optic nerve and the importance of nerve fiber layer hemorrhage Provides an integrated approach to neovascular glaucoma merging treatment to the retina, with the use of new anti-VEGF drugs, tubes, and shunts to achieve the best outcome Integrates clinical science with basic science to outline the next steps in glaucoma therapy
Book Synopsis Ten Cate's Oral Histology by : Antonio Nanci
Download or read book Ten Cate's Oral Histology written by Antonio Nanci and published by Elsevier Health Sciences. This book was released on 2008-01-01 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Accompanying CD-ROM contains ... "150 color images with legends, 472 book figures with legends, 438 multiple choice test questions, and 119 interactive drag-and-drop exercises." -- from CD-ROM Welcome screen.
Book Synopsis Periodontal Regeneration by : Alan M. Polson
Download or read book Periodontal Regeneration written by Alan M. Polson and published by Quintessence Publishing (IL). This book was released on 1994 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: They assert that regeneration can be achieved only by proper understanding of all cellular, tissue, and clinical components, and they provide the foundation necessary for this understanding.
Book Synopsis Functional Tissue Engineering by : Farshid Guilak
Download or read book Functional Tissue Engineering written by Farshid Guilak and published by Springer Science & Business Media. This book was released on 2003-07-09 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: -Softcover reprint of a successful hardcover reference (370 copies sold) -Price to be accessible to the rapidly increasing population of students and investigators in the field of tissue engineering -Chapters written by well-known researchers discuss issues in functional tissue engineering as well as provide guidelines and a summary of the current state of technology
Book Synopsis Principles of Bone Biology by : John P. Bilezikian
Download or read book Principles of Bone Biology written by John P. Bilezikian and published by Academic Press. This book was released on 2008-09-29 with total page 2074 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Bone Biology provides the most comprehensive, authoritative reference on the study of bone biology and related diseases. It is the essential resource for anyone involved in the study of bone biology. Bone research in recent years has generated enormous attention, mainly because of the broad public health implications of osteoporosis and related bone disorders. - Provides a "one-stop" shop. There is no need to search through many research journals or books to glean the information one wants...it is all in one source written by the experts in the field - The essential resource for anyone involved in the study of bones and bone diseases - Takes the reader from the basic elements of fundamental research to the most sophisticated concepts in therapeutics - Readers can easily search and locate information quickly as it will be online with this new edition
Author :Venkatram Prasad Shastri Publisher :Springer Science & Business Media ISBN 13 :9048187885 Total Pages :414 pages Book Rating :4.0/5 (481 download)
Book Synopsis Advances in Regenerative Medicine: Role of Nanotechnology, and Engineering Principles by : Venkatram Prasad Shastri
Download or read book Advances in Regenerative Medicine: Role of Nanotechnology, and Engineering Principles written by Venkatram Prasad Shastri and published by Springer Science & Business Media. This book was released on 2010-08-14 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book summarizes the NATO Advanced Research Workshop (ARW) on “Nanoengineered Systems for Regenerative Medicine” that was organized under the auspices of the NATO Security through Science Program. I would like to thank NATO for supporting this workshop via a grant to the co-directors. The objective of ARW was to explore the various facets of regenerative me- cine and to highlight role of the “the nano-length scale” and “nano-scale systems” in defining and controlling cell and tissue environments. The development of novel tissue regenerative strategies require the integration of new insights emerging from studies of cell-matrix interactions, cellular signalling processes, developmental and systems biology, into biomaterials design, via a systems approach. The chapters in the book, written by the leading experts in their respective disciplines, cover a wide spectrum of topics ranging from stem cell biology, developmental biology, ce- matrix interactions, and matrix biology to surface science, materials processing and drug delivery. We hope the contents of the book will provoke the readership into developing regenerative medicine paradigms that combine these facets into cli- cally translatable solutions. This NATO meeting would not have been successful without the timely help of Dr. Ulrike Shastri, Sanjeet Rangarajan and Ms. Sabine Benner, who assisted in the organization and implementation of various elements of this meeting. Thanks are also due Dr. Fausto Pedrazzini and Ms. Alison Trapp at NATO HQ (Brussels, Belgium). The commitment and persistence of Ms.
Book Synopsis McDonald and Avery's Dentistry for the Child and Adolescent - E-Book by : Jeffrey A. Dean
Download or read book McDonald and Avery's Dentistry for the Child and Adolescent - E-Book written by Jeffrey A. Dean and published by Elsevier Health Sciences. This book was released on 2015-08-10 with total page 720 pages. Available in PDF, EPUB and Kindle. Book excerpt: You can count on McDonald: the go-to source for expert, complete coverage of oral care for infants, children, and teenagers for over half a century. McDonald and Avery’s Dentistry for the Child and Adolescent, 10th Edition discusses pediatric examination, development, morphology, eruption of the teeth, and dental caries in depth — and emphasizes prevention and the treatment of the medically compromised patient. Boasting a new design and handy Evolve site, this new edition by Jeffrey A. Dean equips you with the latest diagnostic and treatment recommendations in the fast-growing field of pediatric dentistry. Complete, one-source coverage includes the best patient outcomes for all of the major pediatric treatments in prosthodontics, restorative dentistry, trauma management, occlusion, gingivitis and periodontal disease, and facial esthetics. A clinical focus includes topics such as such as radiographic techniques, dental materials, pit and fissure sealants, and management of cleft lip and palate. Practical discussions include practice management and how to deal with child abuse and neglect. Evolve site provides you with the best learning tools and resources. UPDATED! More emphasis on preventative care and treatment of medically compromised patients helps you provide more effective care. NEW! Easier-to-follow design.
Book Synopsis Bone Tissue Engineering by : Jeffrey O. Hollinger
Download or read book Bone Tissue Engineering written by Jeffrey O. Hollinger and published by CRC Press. This book was released on 2004-10-14 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focusing on bone biology, Bone Tissue Engineering integrates basic sciences with tissue engineering. It includes contributions from world-renowned researchers and clinicians who discuss key topics such as different models and approaches to bone tissue engineering, as well as exciting clinical applications for patients. Divided into four sections, t
