The Role Of Biofilms In The Development And Dissemination Of Microbial Resistance Within The Food Industry

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The Role of Biofilms in the Development and Dissemination of Microbial Resistance within the Food Industry

Author : Efstathios Giaouris
Publisher : MDPI
ISBN 13 : 3039435515
Total Pages : 100 pages
Book Rating : 4.0/5 (394 download)

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Book Synopsis The Role of Biofilms in the Development and Dissemination of Microbial Resistance within the Food Industry by : Efstathios Giaouris

Download or read book The Role of Biofilms in the Development and Dissemination of Microbial Resistance within the Food Industry written by Efstathios Giaouris and published by MDPI. This book was released on 2020-12-15 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biofilms are multicellular sessile microbial communities embedded in hydrated extracellular polymeric matrices. Their formation is common in microbial life in most environments, whereas those formed on food-processing surfaces are of considerable interest in the context of food hygiene. Biofilm cells express properties that are distinct from planktonic ones, in particular, due to their notorious resistance to antimicrobial agents. Thus, a special feature of biofilms is that once they have developed, they are hard to eradicate, even when careful sanitization procedures are regularly applied. A large amount of ongoing research has investigated how and why surface-attached microbial communities develop such resistance, and several mechanisms can be acknowledged, such as heterogeneous metabolic activity, cell adaptive responses, diffusion limitations, genetic and functional diversification, and microbial interactions. The articles contained in this Special Issue deal with biofilms of some important food-related bacteria (including common pathogens such as Salmonella enterica, Listeria monocytogenes, and Staphylococcus aureus, as well as spoilage-causing spore-forming bacilli), providing novel insights into their resistance mechanisms and implications, together with novel methods (e.g., use of protective biofilms formed by beneficial bacteria, enzymes) that could be used to overcome resistance and thus improve the safety of our food supply and protect public health.

Focus on Bacterial Biofilms

Author : Theerthankar Das
Publisher : BoD – Books on Demand
ISBN 13 : 1803557958
Total Pages : 393 pages
Book Rating : 4.8/5 (35 download)

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Book Synopsis Focus on Bacterial Biofilms by : Theerthankar Das

Download or read book Focus on Bacterial Biofilms written by Theerthankar Das and published by BoD – Books on Demand. This book was released on 2022-11-02 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bacterial biofilms are colonies of bacterial cells embedded in their self-produced matrix composed of polysaccharides, DNA, and proteins. They protect bacterial cells against antibiotics, antibacterial agents, soaps and detergents, and shear stress. Some of the most common biofilm-associated infections in humans include urinary tract infections, infection of wounds and surgical sites, diabetic foot ulcers, dental caries (tooth decay) and gingivitis (gum inflammation), ventilator-associated infections, sinusitis, microbial keratitis, secondary infection related to Covid-19 and other viral infections, and so on. Bacterial resistance to common antibiotics (e.g., penicillin, gentamycin, erythromycin, ciprofloxacin, etc.) is driving us to a catastrophic failure of our health systems. Strategies to develop novel antibacterial agents and technology must be prioritized to combat and eradicate biofilms and their associated challenges. This book provides a comprehensive overview of biofilms with chapters on bacterial virulence factors, quorum sensing in bacteria, antimicrobial resistance in bacteria, strategies to develop new antibacterial agents, and much more.

Mechanisms of antibiotic resistance

Author : Jun Lin
Publisher : Frontiers Media SA
ISBN 13 : 2889195260
Total Pages : 226 pages
Book Rating : 4.8/5 (891 download)

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Book Synopsis Mechanisms of antibiotic resistance by : Jun Lin

Download or read book Mechanisms of antibiotic resistance written by Jun Lin and published by Frontiers Media SA. This book was released on 2015-06-01 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antibiotics represent one of the most successful forms of therapy in medicine. But the efficiency of antibiotics is compromised by the growing number of antibiotic-resistant pathogens. Antibiotic resistance, which is implicated in elevated morbidity and mortality rates as well as in the increased treatment costs, is considered to be one of the major global public health threats (www.who.int/drugresistance/en/) and the magnitude of the problem recently prompted a number of international and national bodies to take actions to protect the public (http://ec.europa.eu/dgs/health_consumer/docs/road-map-amr_en.pdf: http://www.who.int/drugresistance/amr_global_action_plan/en/; http://www.whitehouse.gov/sites/default/files/docs/carb_national_strategy.pdf). Understanding the mechanisms by which bacteria successfully defend themselves against the antibiotic assault represent the main theme of this eBook published as a Research Topic in Frontiers in Microbiology, section of Antimicrobials, Resistance, and Chemotherapy. The articles in the eBook update the reader on various aspects and mechanisms of antibiotic resistance. A better understanding of these mechanisms should facilitate the development of means to potentiate the efficacy and increase the lifespan of antibiotics while minimizing the emergence of antibiotic resistance among pathogens.

Nanotechnology Horizons in Food Process Engineering

Author : Megh R. Goyal
Publisher : CRC Press
ISBN 13 : 100061431X
Total Pages : 400 pages
Book Rating : 4.0/5 (6 download)

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Book Synopsis Nanotechnology Horizons in Food Process Engineering by : Megh R. Goyal

Download or read book Nanotechnology Horizons in Food Process Engineering written by Megh R. Goyal and published by CRC Press. This book was released on 2023-03-10 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although nanotechnology has revolutionized fields such as medicine, genetics, biology, bioengineering, mechanics, and chemistry, its increasing application in the food industry is relatively recent in comparison. Nanotechnology in the food industry is now being explored for creating new flavors, extending food shelf life, and improving food protection and nutritional value, as well as for intelligent nutrient delivery systems, “smart” foods, contaminant detection nanodevices and nanosensors, advanced food processing, antimicrobial chemicals, encapsulation, and green nanomaterials. This new three-volume set addresses a multitude of topical issues and new developments in the field. Volume 1 focuses on food preservation, food packaging, and sustainable agriculture, while Volume 2 looks at nanotechnology in food process engineering, applications of biomaterials in food products, and the use of modern nanotechnology for human health. The third volume explores the newest trends in nanotechnology for food applications for improving food delivery systems. Together, these three volumes provide a comprehensive and in-depth look at the emerging status of nanotechnology in the food processing industry, explaining the benefits and drawbacks of various methodologies that will aid in the improvement and development of food product sourcing and food hygiene monitoring methods. Volume 1 discusses emerging nanotechnolgical applications in food processing, packaging, and preservation. It focuses on using nanoparticles for safe and nutritional food production, protecting crops from pests, increasing nutritional value, and providing solutions for various environmental issues. This book especially deals with nanotechnology for controlling plant pathogens, food packaging and preservation, agricultural productivity, wastewater treatment, and bioenergy production. Volume 2 discusses nanotechnology use in non-thermal techniques such as high-pressure processing (HPP), pulsed electric fields (PEFs), pulsed light, ultraviolet, microwave, ohmic heating, electrospinning, and nano- and microencapsulation. This volume looks at the role and application of minimal processing techniques such as ozone treatment, vacuum drying, osmotic dehydration, dense phase carbon dioxide treatment, and high-pressure assisted freezing. The successful applications of nanotechnologies on juices, meat and fish, fruits and vegetable slices, food surface, purees, milk and milk products, extraction, drying enhancement, and encapsulation of micro-macro nutrients are also considered. The volume also presents several computer-aided techniques that are emerging in the food processing sector, such as robotics, radio frequency identification (RFID), three-dimensional food printing, artificial intelligence, etc. Significant role of food properties in design of specific food and edible packaging films have been elucidated. Nanotechnology Horizons in Food Process Engineering: Volume 3: Trends, Nanomaterials, and Food Delivery provides an overview of the current trends in nanotechnology for food applications and food delivery systems. Topics include a collection of chapters on diverse topics, including the stability of nanoparticles in food, nanobiosensing for the detection of food contaminants, nanotechnology applications in agriculture, the role of nanotechnology in nutrient delivery, how nanotechnology is applied in dairy products, biofunctional magnetic nanoparticles in food safety, the development of nutraceuticals using nanotechnological tools, and more.

Understanding Microbial Biofilms

Author : Surajit Das
Publisher : Elsevier
ISBN 13 : 0323983081
Total Pages : 774 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Understanding Microbial Biofilms by : Surajit Das

Download or read book Understanding Microbial Biofilms written by Surajit Das and published by Elsevier. This book was released on 2022-10-27 with total page 774 pages. Available in PDF, EPUB and Kindle. Book excerpt: **Selected for Doody's Core Titles® 2024 in Microbiology**Understanding Microbial Biofilms: Fundamentals to Applications focuses on the microbial biofilms of different environments. The book provides a comprehensive overview of the fundamental aspects of microbial biofilms, their existence in nature, their significance, and the different clinical and environmental problems associated with them. The book covers both the fundamentals and applications of microbial biofilms, with chapters on the introduction to the microbial community and its architecture, physiology, mechanisms and imaging of biofilms in nature and fungal, algal, and bacillus biofilm control. In addition, the book highlights the molecular and biochemical aspects of bacterial biofilms, providing a compilation of chapters on the bacterial community and communication from different environments. Finally, the book covers recent advancements in various aspects of microbial biofilms including the chapters on their biotechnological applications. All the chapters are written by experts who have been working on different aspects of microbial biofilms. - Illustrates fundamental aspects surrounding microbial biofilms, along with recent advancements - Provides an overview on the principal aspects of biofilms, i.e., formation, regulation, distribution, control, and application - Updates on the progress on biofilm regulation through 'omics' - Serves as a classical manual for all researchers, academicians, and students who would want complete insights on biofilms in a single resource - Covers all recent advancements and amendments on microbial biofilms

Antimicrobial Resistance and Food Safety

Author : Chin-Yi Chen
Publisher : Elsevier
ISBN 13 : 0128013370
Total Pages : 457 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Antimicrobial Resistance and Food Safety by : Chin-Yi Chen

Download or read book Antimicrobial Resistance and Food Safety written by Chin-Yi Chen and published by Elsevier. This book was released on 2015-04-15 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antimicrobial Resistance and Food Safety: Methods and Techniques introduces antimicrobial resistant food-borne pathogens, their surveillance and epidemiology, emerging resistance and resistant pathogens. This analysis is followed by a systematic presentation of currently applied methodology and technology, including advanced technologies for detection, intervention, and information technologies. This reference can be used as a practical guide for scientists, food engineers, and regulatory personnel as well as students in food safety, food microbiology, or food science. - Includes analysis of all major pathogens of concern - Provides many case studies and examples of fundamental research findings - Presents recent advances in methodologies and analytical software - Demonstrates risk assessment using information technologies in foodborne pathogens

Molecular Food Microbiology

Author : Dongyou Liu
Publisher : CRC Press
ISBN 13 : 1351120379
Total Pages : 525 pages
Book Rating : 4.3/5 (511 download)

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Book Synopsis Molecular Food Microbiology by : Dongyou Liu

Download or read book Molecular Food Microbiology written by Dongyou Liu and published by CRC Press. This book was released on 2021-04-11 with total page 525 pages. Available in PDF, EPUB and Kindle. Book excerpt: The elucidation of DNA double helix in 1953 and the publication of DNA cloning protocol in 1973 have put wings under the sail of molecular biology, which has since quietly revolutionized many fields of biological science, including food microbiology. Exploiting the power and versatility of molecular technologies, molecular food microbiology extends and greatly improves on phenotypically based food microbiology, leading to the development of better diagnostics for foodborne infections and intoxications, and contributing to the design of more effective therapeutics and prophylaxes against foodborne diseases. Forming part of the Food Microbiology series, Molecular Food Microbiology provides a state of art coverage on molecular techniques applicable to food microbiology. While the introductory chapter contains an overview on the principles of current DNA, RNA and protein techniques and discusses their utility in helping solve practical problems that food microbiology is facing now and in the future, the remaining chapters present detailed moleuclar analyses of selective foodborne viruses, bacteria, fungi and parasites. Key Features: Contains a state of art overview on moleuclar techniques applicable to food microbiology research and development Presents in-depth molecular analysis of selective foodborne viruses, bacteria, fungi and parasites Highlights the utility of molecular tecniques for accurate diagnosis and effective control of foodborne diseases Includes expert contributions from international scientists involved in molecular food microbiology research Represents a highly informative textbook for students majoring in food, medical, and veterinary microbiology Offers a contemporary reference for scholars and educators wishing to keep abreast with the latest developments in molecular food microbiology With contributions from international scientists involved in molecular food microbiology research, this book constitutes an informative textbook for undergraduates and postgraduates majoring in food, medical, and veterinary microbiology; represents an indispensable guide for food, medical, and veterinary scientists engaged in molecular food microbiology research and development; and offers a contemporary update for scholars and educators trying to keep in touch with the latest developments in molecular food microbiology.

Foodborne Pathogens: Hygiene and Safety

Author : Maria Schirone
Publisher : Frontiers Media SA
ISBN 13 : 2889631869
Total Pages : 536 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Foodborne Pathogens: Hygiene and Safety by : Maria Schirone

Download or read book Foodborne Pathogens: Hygiene and Safety written by Maria Schirone and published by Frontiers Media SA. This book was released on 2019-11-26 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Antimicrobial Resistance in Bacteria of Animal Origin

Author : Frank M. Aarestrup
Publisher : Amer Society for Microbiology
ISBN 13 : 9781555813062
Total Pages : 442 pages
Book Rating : 4.8/5 (13 download)

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Book Synopsis Antimicrobial Resistance in Bacteria of Animal Origin by : Frank M. Aarestrup

Download or read book Antimicrobial Resistance in Bacteria of Animal Origin written by Frank M. Aarestrup and published by Amer Society for Microbiology. This book was released on 2006-01 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antimicrobial Resistance in Bacteria of Animal Origin comprehensively examines the current research on antimicrobial resistance in the main veterinary and zoonotic pathogens, including resistance to disinfectants and metals used in agriculture.

Antibiofilm Agents

Author : Kendra P. Rumbaugh
Publisher : Springer Science & Business Media
ISBN 13 : 3642538339
Total Pages : 495 pages
Book Rating : 4.6/5 (425 download)

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Book Synopsis Antibiofilm Agents by : Kendra P. Rumbaugh

Download or read book Antibiofilm Agents written by Kendra P. Rumbaugh and published by Springer Science & Business Media. This book was released on 2014-05-08 with total page 495 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a survey of recent advances in the development of antibiofilm agents for clinical and environmental applications. The fact that microbes exist in structured communities called biofilms has slowly become accepted within the medical community. We now know that over 80% of all infectious diseases are biofilm-related; however, significant challenges still lie in our ability to diagnose and treat these extremely recalcitrant infections. Written by experts from around the globe, this book offers a valuable resource for medical professionals seeking to treat biofilm-related disease, academic and industry researchers interested in drug discovery and instructors who teach courses on microbial pathogenesis and medical microbiology.

Microbial Biofilms

Author : Dharumadurai Dhanasekaran
Publisher : BoD – Books on Demand
ISBN 13 : 9535124358
Total Pages : 526 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Microbial Biofilms by : Dharumadurai Dhanasekaran

Download or read book Microbial Biofilms written by Dharumadurai Dhanasekaran and published by BoD – Books on Demand. This book was released on 2016-07-13 with total page 526 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the book Microbial Biofilms: Importance and applications, eminent scientists provide an up-to-date review of the present and future trends on biofilm-related research. This book is divided with four subdivisions as biofilm fundamentals, applications, health aspects, and their control. Moreover, this book also provides a comprehensive account on microbial interactions in biofilms, pyocyanin, and extracellular DNA in facilitating Pseudomonas aeruginosa biofilm formation, atomic force microscopic studies of biofilms, and biofilms in beverage industry. The book comprises a total of 21 chapters from valued contributions from world leading experts in Australia, Bulgaria, Canada, China, Serbia, Germany, Italy, Japan, the United Kingdom, the Kingdom of Saudi Arabia, Republic of Korea, Mexico, Poland, Portugal, and Turkey. This book may be used as a text or reference for everyone interested in biofilms and their applications. It is also highly recommended for environmental microbiologists, soil scientists, medical microbiologists, bioremediation experts, and microbiologists working in biocorrosion, biofouling, biodegradation, water microbiology, quorum sensing, and many other related areas. Scientists in academia, research laboratories, and industry will also find it of interest.

Microplastic in the Environment: Pattern and Process

Author : Michael S. Bank
Publisher : Springer Nature
ISBN 13 : 3030786277
Total Pages : 364 pages
Book Rating : 4.0/5 (37 download)

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Book Synopsis Microplastic in the Environment: Pattern and Process by : Michael S. Bank

Download or read book Microplastic in the Environment: Pattern and Process written by Michael S. Bank and published by Springer Nature. This book was released on 2021-10-09 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book examines global plastic pollution, an issue that has become a critical societal challenge with implications for environmental and public health. This volume provides a comprehensive, holistic analysis on the plastic cycle and its subsequent effects on biota, food security, and human exposure. Importantly, global environmental change and its associated, systems-level processes, including atmospheric deposition, ecosystem complexity, UV exposure, wind patterns, water stratification, ocean circulation, etc., are all important direct and indirect factors governing the fate, transport and biotic and abiotic processing of plastic particles across ecosystem types. Furthermore, the distribution of plastic in the ocean is not independent of terrestrial ecosystem dynamics, since much of the plastic in marine ecosystems originates from land and should therefore be evaluated in the context of the larger plastic cycle. Changes in species size, distribution, habitat, and food web complexity, due to global environmental change, will likely alter trophic transfer dynamics and the ecological effects of nano- and microplastics. The fate and transport dynamics of plastic particles are influenced by their size, form, shape, polymer type, additives, and overall ecosystem conditions. In addition to the risks that plastics pose to the total environment, the potential impacts on human health and exposure routes, including seafood consumption, and air and drinking water need to be assessed in a comprehensive and quantitative manner. Here I present a holistic and interdisciplinary book volume designed to advance the understanding of plastic cycling in the environment with an emphasis on sources, fate and transport, ecotoxicology, climate change effects, food security, microbiology, sustainability, human exposure and public policy.

Pathogenic Bacteria

Author : Sahra Kırmusaoğlu
Publisher : BoD – Books on Demand
ISBN 13 : 1789859875
Total Pages : 248 pages
Book Rating : 4.7/5 (898 download)

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Book Synopsis Pathogenic Bacteria by : Sahra Kırmusaoğlu

Download or read book Pathogenic Bacteria written by Sahra Kırmusaoğlu and published by BoD – Books on Demand. This book was released on 2020-12-09 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pathogenic bacteria are the main problem in hospital- and community-acquired infections. As bacteria continue to develop more resistance to antibiotics, it is imperative to develop antibacterial treatment strategies. Written by experts from all over the world, this book examines pathogenic bacteria and their link to multidrug resistance. Over thirteen chapters, it presents examples of pathogenesis, virulence factors, and treatment strategies.

Safety assurance during food processing

Author : Frans J.M. Smulders
Publisher : BRILL
ISBN 13 : 9086865224
Total Pages : 442 pages
Book Rating : 4.0/5 (868 download)

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Book Synopsis Safety assurance during food processing by : Frans J.M. Smulders

Download or read book Safety assurance during food processing written by Frans J.M. Smulders and published by BRILL. This book was released on 2023-08-28 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Microbial agents (particularly bacteria) represent the greatest risk to public health. The traditional end-product oriented food inspection systems are inadequate for identifying and eliminating the usually symptomless animal carriers of agents causing foodborne infections and intoxications. Modern, risk-based, prevention approaches are the only effective way to reduce the prevalence of these hazards from our foods. As an additional 'safety-valve' microbial decontamination procedures are currently being suggested and its implementation in industrial food processing has, at least in some parts of the world, met with governmental approval. The residues in foods of some non-microbial agents have more recently also caused substantial consumer disquiet. This equally applies to non-conventional foods containing GMO's. In this publication these issues are addressed by invited expert scientists from various disciplines, many of which have key-positions in EU-funded research programmes on these very topics and/or are advisers to international public health bodies. The editors firmly believe that the very nature of the theme, the excellence of the papers and the holistic approach chosen will draw an audience from both an industry and academic background."

Bacterial Biofilms

Author : Tony Romeo
Publisher : Springer Science & Business Media
ISBN 13 : 3540754180
Total Pages : 302 pages
Book Rating : 4.5/5 (47 download)

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Book Synopsis Bacterial Biofilms by : Tony Romeo

Download or read book Bacterial Biofilms written by Tony Romeo and published by Springer Science & Business Media. This book was released on 2008-02-26 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: Throughout the biological world, bacteria thrive predominantly in surface-attached, matrix-enclosed, multicellular communities or biofilms, as opposed to isolated planktonic cells. This choice of lifestyle is not trivial, as it involves major shifts in the use of genetic information and cellular energy, and has profound consequences for bacterial physiology and survival. Growth within a biofilm can thwart immune function and antibiotic therapy and thereby complicate the treatment of infectious diseases, especially chronic and foreign device-associated infections. Modern studies of many important biofilms have advanced well beyond the descriptive stage, and have begun to provide molecular details of the structural, biochemical, and genetic processes that drive biofilm formation and its dispersion. There is much diversity in the details of biofilm development among various species, but there are also commonalities. In most species, environmental and nutritional conditions greatly influence biofilm development. Similar kinds of adhesive molecules often promote biofilm formation in diverse species. Signaling and regulatory processes that drive biofilm development are often conserved, especially among related bacteria. Knowledge of such processes holds great promise for efforts to control biofilm growth and combat biofilm-associated infections. This volume focuses on the biology of biofilms that affect human disease, although it is by no means comprehensive. It opens with chapters that provide the reader with current perspectives on biofilm development, physiology, environmental, and regulatory effects, the role of quorum sensing, and resistance/phenotypic persistence to antimicrobial agents during biofilm growth.

Antimicrobial Resistance

Author : Mihai Mares
Publisher : BoD – Books on Demand
ISBN 13 : 1839624329
Total Pages : 210 pages
Book Rating : 4.8/5 (396 download)

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Book Synopsis Antimicrobial Resistance by : Mihai Mares

Download or read book Antimicrobial Resistance written by Mihai Mares and published by BoD – Books on Demand. This book was released on 2021-03-03 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tackling the realities of the antimicrobial resistance (AMR) situation today is no longer uncommon. Many battles have been fought in the past since the discovery of antibiotics between man and microbes. In the tussle of new antibiotic modifications, the transmission of resistant genes, both vertically and horizontally unveils yet another resistant attribute for the microbe, for it only to be faced with a more powerful, wide spectrum antibiotic; the cycle continues-and the winner is yet to be known. This book aims to provide some insight into various molecular mechanisms, agricultural mitigation methods, and the One Health applications to maybe, just maybe, tip the scales towards us.

Biofilms in Infection Prevention and Control

Author : Steven L. Percival
Publisher : Academic Press
ISBN 13 : 0123977517
Total Pages : 394 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Biofilms in Infection Prevention and Control by : Steven L. Percival

Download or read book Biofilms in Infection Prevention and Control written by Steven L. Percival and published by Academic Press. This book was released on 2014-01-30 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biofilms in Infection and Disease Control: A Healthcare Handbook outlines the scientific evidence and rationale for the prevention of infection, the role biofilms play in infection control, and the issues concerning their resistance to antimicrobials. This book provides practical guidance for healthcare and infection control professionals, as well as students, for preventing and controlling infection. Biofilms are the most common mode of bacterial growth in nature. Highly resistant to antibiotics and antimicrobials, biofilms are the source of more than 65 percent of health care associated infections (HCAI), which, according to the WHO, affect 1.4 million people annually. Biofilms are involved in 80 percent of all microbial infections in the body, including those associated with medical devices such as catheters, endotracheal tubes, joint prostheses, and heart valves. Biofilms are also the principle causes of infections of the middle-ear, dental caries, gingivitis, prostatitis and cystic fibrosis. Importantly, biofilms also significantly delay wound healing and reduce antimicrobial efficiency in at-risk or infected skin wounds. - Provides specific procedures for controlling and preventing infection - Includes case studies of HCAI, and identifies appropriate treatments - Presents national government standards for infection prevention and control - Includes extensive references and links to websites for further information