Protein Targeting to Mitochondria

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Author :
Publisher : Elsevier
ISBN 13 : 0080877001
Total Pages : 377 pages
Book Rating : 4.0/5 (88 download)

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Book Synopsis Protein Targeting to Mitochondria by : F.U. Hartl

Download or read book Protein Targeting to Mitochondria written by F.U. Hartl and published by Elsevier. This book was released on 1997-02-24 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: A large number of newly-synthesized polypeptides must cross one or several intracellular membranes to reach their functional locations in the eukaryotic cell. The mechanisms of protein trafficking, in particular the post-translational targeting and membrane translocation of proteins, are of fundamental biological importance and are the focus of intensive research world-wide. For more than 15 years, mitochondria have served as the paradigm organelle system to study these processes. Although key questions, such as how precisely proteins cross a membrane, still remain to be answered, exciting progress has been made in understanding the basic pathways of protein import into mitochondria and the components involved. In addition to a fascinating richness and complexity in detail, the analysis of mitochondrial protein import has revealed mechanistic principles of general significance: Major discoveries include the demonstration of the requirement of an unfolded state for translocation and of the essential role of molecular chaperones on both sides of the membranes in maintaining a translocation-competent conformation and in protein folding after import. It is becoming clear how a polypeptide chain is "reeled" across the membrane in an ATP-dependent process by the functional cooperation of membrane proteins, presumably constituting part of a transmembrane channel, with peripheral components at the trans-side of the membrane.In this volume, eminent experts in the field take the time to review the central aspects of mitochondrial biogenesis. The logical order of the 16 chapters is determined by the sequence of steps during protein import, starting with the events taking place in the cytosol, followed by the recognition of targeting signals, the translocation of precursor proteins across the outer and inner membranes, their proteolytic processing and intramitochondrial sorting, and finally their folding and oligomeric assembly. In addition, the mechanisms involved in the export of mitochondrially encoded proteins as well as recent advances in understanding the division and inheritance of mitochondria will be discussed.

Plant Mitochondria

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Author :
Publisher : Humana
ISBN 13 : 9781493926381
Total Pages : 0 pages
Book Rating : 4.9/5 (263 download)

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Book Synopsis Plant Mitochondria by : James Whelan

Download or read book Plant Mitochondria written by James Whelan and published by Humana. This book was released on 2015-04-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The chapters compiled in this detailed collection outline a number of methods used to study plant mitochondria today, starting from the isolation of mitochondria to detailed analyses of RNA, protein and enzymatic activities. Given that the ability to uncover mitochondria’s unique features is underpinned by current methodology, this book explores the subject from morphology to detailed molecular mechanisms. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls. Practical and authoritative, Plant Mitochondria: Methods and Protocols serves as a vital resource to beginners in the field as well as to expert researchers who find themselves being pulled into the field of mitochondrial research as it links to so many important aspects of plant cell biology.

Membrane Trafficking

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Publisher : Springer Science & Business Media
ISBN 13 : 9781588299253
Total Pages : 430 pages
Book Rating : 4.2/5 (992 download)

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Book Synopsis Membrane Trafficking by : Ales Vancura

Download or read book Membrane Trafficking written by Ales Vancura and published by Springer Science & Business Media. This book was released on 2008-08-28 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: As membrane trafficking research has expanded over the past thirty years, a remarkable convergence of information has been gained by using genetic approaches in yeast cells with biochemical approaches in mammalian cells. This book reflects these advances by devoting one section of the book to yeast cells and the other to mammalian cells, with each section providing both classic and cutting-edge techniques to study macromolecular transport across the membranes.

Evolution of the Protein Synthesis Machinery and Its Regulation

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Author :
Publisher : Springer
ISBN 13 : 3319394681
Total Pages : 564 pages
Book Rating : 4.3/5 (193 download)

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Book Synopsis Evolution of the Protein Synthesis Machinery and Its Regulation by : Greco Hernández

Download or read book Evolution of the Protein Synthesis Machinery and Its Regulation written by Greco Hernández and published by Springer. This book was released on 2016-08-10 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: The “omics” era has given a new perspective to the findings on the origin and evolution of the process of translation. This book provides insight into the evolution of the translation process and machinery from a modern perspective. Written by leading experts in molecular biology, this text looks into the origins and evolution of the protein synthetic machinery.

Cumulated Index Medicus

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Publisher :
ISBN 13 :
Total Pages : 1348 pages
Book Rating : 4.3/5 ( download)

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Book Synopsis Cumulated Index Medicus by :

Download or read book Cumulated Index Medicus written by and published by . This book was released on 1974 with total page 1348 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Impairment of Mitochondrial Protein Synthesis

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Publisher :
ISBN 13 :
Total Pages : 102 pages
Book Rating : 4.:/5 (27 download)

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Book Synopsis Impairment of Mitochondrial Protein Synthesis by : Luitzen de Jong

Download or read book Impairment of Mitochondrial Protein Synthesis written by Luitzen de Jong and published by . This book was released on 1979 with total page 102 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Transfer RNA in Protein Synthesis

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Author :
Publisher : CRC Press
ISBN 13 : 1351085840
Total Pages : 446 pages
Book Rating : 4.3/5 (51 download)

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Book Synopsis Transfer RNA in Protein Synthesis by : Dolph L. Hatfield

Download or read book Transfer RNA in Protein Synthesis written by Dolph L. Hatfield and published by CRC Press. This book was released on 2018-01-10 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transfer RNA in Protein Synthesis is a comprehensive volume focusing on important aspects of codon usage, selection, and discrimination in the genetic code. The many different functions of tRNA and the specialized roles of the corresponding codewords in protein synthesis from initiation through termination are thoroughly discussed. Variations that occur in the initiation process, in reading the genetic code, and in the selection of codons are discussed in detail. The book also examines the role of modified nucleosides in tRNA interactions, tRNA discrimination in aminoacylation, codon discrimination in translation, and selective use of termination codons. Other topics covered include the adaptation of the tRNA population to codon usage in cells and cellular organelles, the occurence of UGA as a codon for selenocysteine in the universal genetic code, new insights into translational context effects and in codon bias, and the molecular biology of tRNA in retroviruses. The contributions of outstanding molecular biologists engaged in tRNA research and prominent investigators from other scientific disciplines, specifically retroviral research, make Transfer RNA in Protein Synthesis an essential reference work for microbiologists, biochemists, molecular biologists, geneticists, and other researchers involved in protein synthesis research.

Protein Synthesis and Targeting in Yeast

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3642849210
Total Pages : 416 pages
Book Rating : 4.6/5 (428 download)

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Book Synopsis Protein Synthesis and Targeting in Yeast by : Alistair J.P. Brown

Download or read book Protein Synthesis and Targeting in Yeast written by Alistair J.P. Brown and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to fundamental similarities between the yeast Saccharomyces cerevisiae and multicellular organisms at the molecular level, and the powerful range of experimental tools available for this yeast, S. cerevisiae is proving an ideal model system for studies on protein synthesis and targeting. The topics covered are: - Messenger RNA stability and translation.- The translation apparatus. - Translational control andfidelity. - Protein targeting to the mitochondrion. - Nuclear transport. - The secretory pathway. - Protein folding and degradation. - Protein splicing. Modern and often novel molecular, genetic and biochemical approaches as well as most recent data are provided. The reader will gain a comprehensive view of the current status of the field.

Genetics and Biotechnology

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Publisher : Springer Science & Business Media
ISBN 13 : 3662074265
Total Pages : 440 pages
Book Rating : 4.6/5 (62 download)

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Book Synopsis Genetics and Biotechnology by : Ulrich Kück

Download or read book Genetics and Biotechnology written by Ulrich Kück and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since publication of the first edition of Volume II in 1995, several developments in fungal molecular biology - such as fungal genome projects - have progressed tremendously. This in turn has affected fundamental genetics as well as biotechnology. To accommodate these developments, the second edition has been completely updated and all chapters have been revised. In addition, the volume contains five new chapters dealing with different aspects of fungal molecular genetics. Topics include: Nuclear and extranuclear genetics; functional genomics; biotechnical genetics; yeasts and filamentous fungi.

Research Grants Index

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Publisher :
ISBN 13 :
Total Pages : 1132 pages
Book Rating : 4.3/5 ( download)

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Book Synopsis Research Grants Index by : National Institutes of Health (U.S.). Division of Research Grants

Download or read book Research Grants Index written by National Institutes of Health (U.S.). Division of Research Grants and published by . This book was released on 1972 with total page 1132 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Genetics and Biotechnology

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Publisher : Springer Science & Business Media
ISBN 13 : 9783540427704
Total Pages : 384 pages
Book Rating : 4.4/5 (277 download)

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Book Synopsis Genetics and Biotechnology by : Karl Esser

Download or read book Genetics and Biotechnology written by Karl Esser and published by Springer Science & Business Media. This book was released on 2004-01-22 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Keywords: Fungi, biotechnology, fungal molecular biology, molecular genetics, mycology, yeast.

Bibliography of Agriculture

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Publisher :
ISBN 13 :
Total Pages : 1272 pages
Book Rating : 4.3/5 (243 download)

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Book Synopsis Bibliography of Agriculture by :

Download or read book Bibliography of Agriculture written by and published by . This book was released on 1972 with total page 1272 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Products of mitochondrial protein synthesis in meurospora crass...

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Publisher :
ISBN 13 :
Total Pages : 112 pages
Book Rating : 4.:/5 (27 download)

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Book Synopsis Products of mitochondrial protein synthesis in meurospora crass... by : Peter van 't Sant

Download or read book Products of mitochondrial protein synthesis in meurospora crass... written by Peter van 't Sant and published by . This book was released on 19?? with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Enzymes of Biological Membranes

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Publisher : Springer Science & Business Media
ISBN 13 : 1468446045
Total Pages : 605 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis The Enzymes of Biological Membranes by : Anthony Martonosi

Download or read book The Enzymes of Biological Membranes written by Anthony Martonosi and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 605 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the first edition of The Enzymes of Biological Membranes, published in four volumes in 1976, we collected the mass of widely scattered information on membrane-linked enzymes and metabolic processes up to about 1975. This was a period of transition from the romantic phase of membrane biochemistry, preoccupied with conceptual developments and the general properties of membranes, to an era of mounting interest in the specific properties of membrane-linked enzymes analyzed from the viewpoints of modem enzymology. The level of sophistication in various areas of membrane research varied widely; the structures of cytochrome c and cytochrome b were known s to atomic detail, while the majority of membrane-linked enzymes had not even been isolated. In the intervening eight years our knowledge of membrane-linked enzymes ex panded beyond the wildest expectations. The purpose of the second edition of The Enzymes of Biological Membranes is to record these developments. The first volume describes the physical and chemical techniques used in the analysis of the structure and dynamics of biological membranes. In the second volume the enzymes and met abolic systems that participate in the biosynthesis of cell and membrane components are discussed. The third and fourth volumes review recent developments in active transport, oxidative phosphorylation, and photosynthesis.

Molecular Aspects of Animal Development

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Publisher : Academic Press
ISBN 13 : 1483272710
Total Pages : 526 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Molecular Aspects of Animal Development by : Rudolf Weber

Download or read book Molecular Aspects of Animal Development written by Rudolf Weber and published by Academic Press. This book was released on 2014-05-10 with total page 526 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Biochemistry of Animal Development, Volume III: Molecular Aspects of Animal Development provides an account of the developments in the molecular approach to vertebrate development with particular emphasis on the functions of nucleic acids. The book discusses topics on oocyte maturation, transcriptional patterns in early development, the post-transcriptional control of gene expression, and the significance of gene amplification. Morphogenetic substances, growth-promoting proteins, and the functional differentiation of mitochondria in embryonic systems are covered as well. Biochemists, biologists, and zoologists will find the book invaluable.

Genes, Enzymes, and Populations

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Publisher : Springer Science & Business Media
ISBN 13 : 1468428802
Total Pages : 357 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Genes, Enzymes, and Populations by : Adrian Srb

Download or read book Genes, Enzymes, and Populations written by Adrian Srb and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present volume includes the large majority of papers given at the symposium entitled "Fundamental Approaches to Plant and Animal Improvement," held at Cali, Colombia, in November, 1972. The primary focal points were on various genetic mechanisms, including gene action and mutation, the development of phenotypic attributes, and on evolution, including that controlled by man for agricultural purposes. In fact, very little referring in any particular way to animal improvement was included, while a great deal of attention was paid to higher plants and to microorganisms. On the other hand, both the population genetics of insects and insect control were considered. Thus Genes, Enzymes, and Populations, the title given to this published work, seems to me to represent somewhat more fairly the contents than does the original symposium title. Given the intent of the symposium, which is expressed in the original title, the published record cannot be expected to be a neatly packaged presentation of some highly defined subject matter. Indeed the diverse subjects represent some, but by no means all, of the varied and dynamic scientific activities that need to be components in the improvement and production of agriculturally Significant plants at a time when world populations are rapidly increasing and shortages of food occurring. In any case, the organizers of the symposium wisely decided that considerations of environment as well as of genetics should be introduced into the thinking of the group and that physiology and molecular biology could not be ignored.

Genetic Interaction and Gene Transfer

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Author :
Publisher :
ISBN 13 :
Total Pages : 398 pages
Book Rating : 4.:/5 (89 download)

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Book Synopsis Genetic Interaction and Gene Transfer by : Carl William Anderson

Download or read book Genetic Interaction and Gene Transfer written by Carl William Anderson and published by . This book was released on 1978 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: