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The Potential Effect And Mechanism Of Chinese Traditional Medicine On Vascular Homeostasis And Remodeling
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Book Synopsis The Potential Effect and Mechanism of Chinese Traditional Medicine on Vascular Homeostasis and Remodeling by : Yuliang Wang
Download or read book The Potential Effect and Mechanism of Chinese Traditional Medicine on Vascular Homeostasis and Remodeling written by Yuliang Wang and published by Frontiers Media SA. This book was released on 2021-02-02 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Potential Effect and Mechanism of Traditional Medicine on Vascular Homeostasis and Remodeling: An Update by : Yuliang Wang
Download or read book The Potential Effect and Mechanism of Traditional Medicine on Vascular Homeostasis and Remodeling: An Update written by Yuliang Wang and published by Frontiers Media SA. This book was released on 2022-03-28 with total page 110 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Potential Effects and Mechanisms of Chinese Traditional Medicine on Bone Homeostasis and Remodeling by : Jun Liu
Download or read book The Potential Effects and Mechanisms of Chinese Traditional Medicine on Bone Homeostasis and Remodeling written by Jun Liu and published by Frontiers Media SA. This book was released on 2023-09-20 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: Osteoporosis is a systemic skeletal disease, strongly affecting postmenopausal women and characterized by an increased risk of bone fragility and a decrease in bone mass. Bone homeostasis requires a balance between bone-forming osteoblasts and bone-resorbing osteoclasts. When this balance is impaired, normal bone remodelling cannot keep bone mass stable, leading to osteopenia and osteoporosis. About 30–50% of all women in the world suffer from fractures due to osteoporosis throughout their lives. The treatments include improving metabolic abnormalities through complementary and alternative therapies, drug application and surgical therapy for the management of overweight, obesity and hormone metabolism disorder. Chinese traditional medicine has been increasingly considered as an effective therapy for osteoporosis. A series of formulae, herbs and natural products have been indicated for their effects in the prevention and treatment of osteoporosis, such as Liu-Wei-Di-Huang Wan (formula), Morindae Officinalis Radix (herb), Longspur epimedium glycoside (natural product). However, the mechanisms of action remain largely unexplored.
Book Synopsis Bioactive Substances-Mediated Targeted Therapy of Cardio-Cerebrovascular Diseases by : Guixue Wang
Download or read book Bioactive Substances-Mediated Targeted Therapy of Cardio-Cerebrovascular Diseases written by Guixue Wang and published by Frontiers Media SA. This book was released on 2023-03-07 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Vascular Smooth Muscle Cell fate and Vascular Remodeling: Mechanisms, Therapeutic Targets, and Drugs, Volume I by : Ping Song
Download or read book Vascular Smooth Muscle Cell fate and Vascular Remodeling: Mechanisms, Therapeutic Targets, and Drugs, Volume I written by Ping Song and published by Frontiers Media SA. This book was released on 2022-09-26 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Medicinal Plants in the Treatment of Myocardial Injury and Vascular Diseases by : Yusof Kamisah
Download or read book Medicinal Plants in the Treatment of Myocardial Injury and Vascular Diseases written by Yusof Kamisah and published by Frontiers Media SA. This book was released on 2022-04-26 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Polyphenols in Human Health and Disease by : Ronald Ross Watson
Download or read book Polyphenols in Human Health and Disease written by Ronald Ross Watson and published by Academic Press. This book was released on 2013-10-26 with total page 1504 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polyphenols in Human Health and Disease documents antioxidant actions of polyphenols in protection of cells and cell organelles, critical for understanding their health-promoting actions to help the dietary supplement industry. The book begins by describing the fundamentals of absorption, metabolism and bioavailability of polyphenols, as well as the effect of microbes on polyphenol structure and function and toxicity. It then examines the role of polyphenols in the treatment of chronic disease, including vascular and cardiac health, obesity and diabetes therapy, cancer treatment and prevention, and more. - Explores neuronal protection by polyphenol metabolites and their application to medical care - Defines modulation of enzyme actions to help researchers see and study polyphenols' mechanisms of action, leading to clinical applications - Includes insights on polyphenols in brain and neurological functions to apply them to the wide range of aging diseases
Author :United States. Public Health Service. Office of the Surgeon General Publisher : ISBN 13 : Total Pages :728 pages Book Rating :4.:/5 (318 download)
Book Synopsis How Tobacco Smoke Causes Disease by : United States. Public Health Service. Office of the Surgeon General
Download or read book How Tobacco Smoke Causes Disease written by United States. Public Health Service. Office of the Surgeon General and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Book Synopsis Bone Aging and Osteoporosis: Recent Evidence Focusing on Plant-Based Natural Products by : Lingfeng Zeng
Download or read book Bone Aging and Osteoporosis: Recent Evidence Focusing on Plant-Based Natural Products written by Lingfeng Zeng and published by Frontiers Media SA. This book was released on 2024-03-08 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: The human skeleton undergoes a life-long remodeling process. Bone homeostasis requires a potential balance between bone-resorbing osteoclasts and bone-forming osteoblasts. With old age, bone homeostasis undergoes deregulation, and normal bone remodeling could not make bone mass stable, thus causing osteopenia and osteoporosis. Osteoporosis is a systemic bone disease characterized by reduced bone mass, degraded bone microstructure, increased bone fragility and raised risk of fracture. Osteoporosis is a frequently occurring and common disease in the aging population, especially in postmenopausal women and elderly men. The updated research found that one-third of women aged 60 to 70 suffer from osteoporosis; Two-thirds of women aged 80 years or older have osteoporosis. About 20-25% of women over 50 years of age have one or more vertebral fractures. Recent research evidence indicates that an increasing number of plant-based natural products (or secondary metabolites), such as polyunsaturated fatty acids, phytosterols, flavonoids, and other botanicals active compounds, have beneficial effects on the risk of osteoporosis. Compared with conventional therapies, plant-based natural products with thousands of years of medical use experience are gradually approved for clinical use due to fewer adverse reactions, low toxicity, high efficiency and good tolerance. Natural products have been an important source of inspiration for new drug development. However, most of the evidence regarding the anti-osteoporosis effects of natural products comes from in vitro and preclinical in vivo studies, and only a few natural products have been used clinically. All of these above-mentioned still require rigorously designed studies and further verification.
Book Synopsis Anti-fibrotic Drug Discovery by : Jehrod Brenneman
Download or read book Anti-fibrotic Drug Discovery written by Jehrod Brenneman and published by Royal Society of Chemistry. This book was released on 2020-02-17 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fibrosis is a condition with globally high unmet medical need, and as such is a highly active area of academic and pharmaceutical research covering multiple treatment targets, organs, tissues and therapeutic approaches. Anti-fibrotic Drug Discovery is a single source reference for the latest drug-discovery approaches to tackle fibrosis in various tissues, comprehensively covering recent success and future perspectives on emerging therapeutic intervention points. The book highlights significant pre-clinical and clinical drugs currently being developed globally for this disorder. This book is ideal for postgraduate students and researchers with an interest in anti-fibrotic drug discovery as well as clinicians specialising in liver, kidney, heart and lung disease, in which fibrosis plays a key role in pathology.
Book Synopsis Novel ligands and receptors in endocrine disorders by : Huashan Zhao
Download or read book Novel ligands and receptors in endocrine disorders written by Huashan Zhao and published by Frontiers Media SA. This book was released on 2023-06-22 with total page 103 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Exercise for Cardiovascular Disease Prevention and Treatment by : Junjie Xiao
Download or read book Exercise for Cardiovascular Disease Prevention and Treatment written by Junjie Xiao and published by Springer. This book was released on 2017-11-02 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book provides an intensive overview on exercise for cardiovascular disease prevention and treatment, from basic research to clinical practice. The volume firstly summarizes the acute and chronic response to exercise. Secondly, evidence for exercise as medicine for the heart based on clinical studies and basic research is summarized. Thirdly, molecular mechanisms mediating the beneficial effects of exercise including IGF-1-PI3K-AKT signalling, NO signalling, C/EBPB-Cited4 signalling, Non-coding RNAs, epigenetic regulators, mitochondria adaption and exosomes are presented. Finally, exercise dosing, prescription and future prospects are provided. This book will provide valuable reference for researchers in cell biology, physiology, as well as physician, physical therapist in cardiology, sport medicine, etc.
Download or read book Network Pharmacology written by Shao Li and published by Springer Nature. This book was released on 2021-09-29 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book introduces “network pharmacology” as an emerging frontier subject of systematic drug research in the era of artificial intelligence and big data. Network Pharmacology is an original subject of fusion system biology, bioinformatics, network science and other related disciplines. It emphasizes on starting from the overall perspective of the system level and biological networks, the analysis of the laws of molecular association between drugs and their treatment objects, reveals the systematic pharmacological mechanisms of drugs, and guides the research and development of new drugs and clinical diagnosis and treatment. After it was proposed, network pharmacology has been paid attention by researchers, and it has been rapidly developed and widely used. In order to systematically reveal the biological basis of diagnosis and treatment in traditional Chinese medicine and modern medicine, we proposed a new concept of "network target" for the first time, which has become the core theory of "network pharmacology". The core principle of a network target is to construct a biological network that can be used to decipher complex diseases. The network is then used as the therapeutic target, to which multicomponent remedies are applied. This book mainly includes four parts: 1) The concept and theory of network pharmacology; 2) Common analysis methods, databases and software in network pharmacological research; 3) Typical cases of traditional Chinese medicine modernization and modern drug research based on network pharmacology; 4) Network pharmacology practice process based on drugs and diseases.
Download or read book The Endothelium written by Michel Félétou and published by Morgan & Claypool Publishers. This book was released on 2011 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: The endothelium, a monolayer of endothelial cells, constitutes the inner cellular lining of the blood vessels (arteries, veins and capillaries) and the lymphatic system, and therefore is in direct contact with the blood/lymph and the circulating cells. The endothelium is a major player in the control of blood fluidity, platelet aggregation and vascular tone, a major actor in the regulation of immunology, inflammation and angiogenesis, and an important metabolizing and an endocrine organ. Endothelial cells controls vascular tone, and thereby blood flow, by synthesizing and releasing relaxing and contracting factors such as nitric oxide, metabolites of arachidonic acid via the cyclooxygenases, lipoxygenases and cytochrome P450 pathways, various peptides (endothelin, urotensin, CNP, adrenomedullin, etc.), adenosine, purines, reactive oxygen species and so on. Additionally, endothelial ectoenzymes are required steps in the generation of vasoactive hormones such as angiotensin II. An endothelial dysfunction linked to an imbalance in the synthesis and/or the release of these various endothelial factors may explain the initiation of cardiovascular pathologies (from hypertension to atherosclerosis) or their development and perpetuation. Table of Contents: Introduction / Multiple Functions of the Endothelial Cells / Calcium Signaling in Vascular Cells and Cell-to-Cell Communications / Endothelium-Dependent Regulation of Vascular Tone / Conclusion / References
Book Synopsis Cardioimmunology: Inflammation and Immunity in Cardiovascular Disease by : Mohamed Boutjdir
Download or read book Cardioimmunology: Inflammation and Immunity in Cardiovascular Disease written by Mohamed Boutjdir and published by Frontiers Media SA. This book was released on 2020-01-30 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis MicroRNAs in Cancer by : Cesar Lopez-Camarillo
Download or read book MicroRNAs in Cancer written by Cesar Lopez-Camarillo and published by CRC Press. This book was released on 2013-02-22 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: MicroRNA (miRNA) biology is a cutting-edge topic in basic as well as biomedical research. This is a specialized book focusing on the current understanding of the role of miRNAs in the development, progression, invasion, and metastasis of diverse types of cancer. It also reviews their potential for applications in cancer diagnosis, prognosis, and th
Book Synopsis New Insights Into Renal Fibrosis and Therapeutic Effects of Natural Products by : Dan-Qian Chen
Download or read book New Insights Into Renal Fibrosis and Therapeutic Effects of Natural Products written by Dan-Qian Chen and published by Frontiers Media SA. This book was released on 2022-05-30 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt:
