The Postgenomic Condition

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The Postgenomic Condition

Author : Jenny Reardon
Publisher : University of Chicago Press
ISBN 13 : 022651045X
Total Pages : 320 pages
Book Rating : 4.2/5 (265 download)

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Book Synopsis The Postgenomic Condition by : Jenny Reardon

Download or read book The Postgenomic Condition written by Jenny Reardon and published by University of Chicago Press. This book was released on 2017-12-29 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: The postgenomic condition: an introduction -- The information of life or the life of information? -- Inclusion: can genomics be antiracist? -- Who represents the human genome? What is the human genome? -- Genomics for the people or the rise of the machines? -- Genomics for the 98 percent? -- The genomic open 2.0: the public v. the public -- Life on Third: knowledge and justice after the genome -- Epilogue

Gene Regulation and Metabolism

Author : Julio Collado-Vides
Publisher : MIT Press
ISBN 13 : 9780262532686
Total Pages : 326 pages
Book Rating : 4.5/5 (326 download)

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Book Synopsis Gene Regulation and Metabolism by : Julio Collado-Vides

Download or read book Gene Regulation and Metabolism written by Julio Collado-Vides and published by MIT Press. This book was released on 2002 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: An overview of current computational approaches to metabolism and gene regulation.

Race to the Finish

Author : Jenny Reardon
Publisher : Princeton University Press
ISBN 13 : 1400826403
Total Pages : 249 pages
Book Rating : 4.4/5 (8 download)

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Book Synopsis Race to the Finish by : Jenny Reardon

Download or read book Race to the Finish written by Jenny Reardon and published by Princeton University Press. This book was released on 2009-02-09 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the summer of 1991, population geneticists and evolutionary biologists proposed to archive human genetic diversity by collecting the genomes of "isolated indigenous populations." Their initiative, which became known as the Human Genome Diversity Project, generated early enthusiasm from those who believed it would enable huge advances in our understanding of human evolution. However, vocal criticism soon emerged. Physical anthropologists accused Project organizers of reimporting racist categories into science. Indigenous-rights leaders saw a "Vampire Project" that sought the blood of indigenous people but not their well-being. More than a decade later, the effort is barely off the ground. How did an initiative whose leaders included some of biology's most respected, socially conscious scientists become so stigmatized? How did these model citizen-scientists come to be viewed as potential racists, even vampires? This book argues that the long abeyance of the Diversity Project points to larger, fundamental questions about how to understand knowledge, democracy, and racism in an age when expert claims about genomes increasingly shape the possibilities for being human. Jenny Reardon demonstrates that far from being innocent tools for fighting racism, scientific ideas and practices embed consequential social and political decisions about who can define race, racism, and democracy, and for what ends. She calls for the adoption of novel conceptual tools that do not oppose science and power, truth and racist ideologies, but rather draw into focus their mutual constitution.

The Gene

Author : Hans-Jörg Rheinberger
Publisher : University of Chicago Press
ISBN 13 : 022647478X
Total Pages : 156 pages
Book Rating : 4.2/5 (264 download)

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Book Synopsis The Gene by : Hans-Jörg Rheinberger

Download or read book The Gene written by Hans-Jörg Rheinberger and published by University of Chicago Press. This book was released on 2018-01-26 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: Few concepts played a more important role in twentieth-century life sciences than that of the gene. Yet at this moment, the field of genetics is undergoing radical conceptual transformation, and some scientists are questioning the very usefulness of the concept of the gene, arguing instead for more systemic perspectives. The time could not be better, therefore, for Hans-Jörg Rheinberger and Staffan Müller-Wille's magisterial history of the concept of the gene. Though the gene has long been the central organizing theme of biology, both conceptually and as an object of study, Rheinberger and Müller-Wille conclude that we have never even had a universally accepted, stable definition of it. Rather, the concept has been in continual flux—a state that, they contend, is typical of historically important and productive scientific concepts. It is that very openness to change and manipulation, the authors argue, that made it so useful: its very mutability enabled it to be useful while the technologies and approaches used to study and theorize about it changed dramatically.

Postgenomics

Author : Sarah S. Richardson
Publisher : Duke University Press
ISBN 13 : 0822375443
Total Pages : 286 pages
Book Rating : 4.8/5 (223 download)

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Book Synopsis Postgenomics by : Sarah S. Richardson

Download or read book Postgenomics written by Sarah S. Richardson and published by Duke University Press. This book was released on 2015-05-29 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ten years after the Human Genome Project’s completion the life sciences stand in a moment of uncertainty, transition, and contestation. The postgenomic era has seen rapid shifts in research methodology, funding, scientific labor, and disciplinary structures. Postgenomics is transforming our understanding of disease and health, our environment, and the categories of race, class, and gender. At the same time, the gene retains its centrality and power in biological and popular discourse. The contributors to Postgenomics analyze these ruptures and continuities and place them in historical, social, and political context. Postgenomics, they argue, forces a rethinking of the genome itself, and opens new territory for conversations between the social sciences, humanities, and life sciences. Contributors. Russ Altman, Rachel A. Ankeny, Catherine Bliss, John Dupré, Michael Fortun, Evelyn Fox Keller, Sabina Leonelli, Adrian Mackenzie, Margot Moinester, Aaron Panofsky, Sarah S. Richardson, Sara Shostak, Hallam Stevens

Spirochete Biology: The Post Genomic Era

Author : Ben Adler
Publisher : Springer
ISBN 13 : 3319896385
Total Pages : 301 pages
Book Rating : 4.3/5 (198 download)

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Book Synopsis Spirochete Biology: The Post Genomic Era by : Ben Adler

Download or read book Spirochete Biology: The Post Genomic Era written by Ben Adler and published by Springer. This book was released on 2018-08-21 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: Spirochetes comprise a fascinating group of bacteria. Although diverse in terms of their habitat, ecology and infectivity for vertebrate and non-vertebrate hosts, they are often considered together because of their similar cellular morphologies. This volume brings together an international group of experts to provide essential insights into spirochete biology, with an emphasis on recent advances made possible by the availability of genome sequences. As such, it offers a valuable resource for microbiologists and other scientists with an interest in spirochete biology.

Essential Concepts in Molecular Pathology

Author : William B. Coleman
Publisher : Academic Press
ISBN 13 : 0128132582
Total Pages : 636 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Essential Concepts in Molecular Pathology by : William B. Coleman

Download or read book Essential Concepts in Molecular Pathology written by William B. Coleman and published by Academic Press. This book was released on 2019-11-23 with total page 636 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essential Concepts in Molecular Pathology, Second Edition, offers an introduction to molecular genetics and the "molecular" aspects of human disease. The book illustrates how pathologists harness their understanding of these entities to develop new diagnostics and treatments for various human diseases. This new edition offers pathology, genetics residents, and molecular pathology fellows an advanced understanding of the molecular mechanisms of disease that goes beyond what they learned in medical and graduate school. By bridging molecular concepts of pathogenesis to the clinical expression of disease in cell, tissue and organ, this fully updated, introductory reference provides the background necessary for an understanding of today's advances in pathology and medicine. - Explains the practice of "molecular medicine" and the translational aspects of molecular pathology, including molecular diagnostics, molecular assessment and personalized medicine - Orients non-pathologists on what pathologists look for and how they interpret their observational findings based on histopathology - Provides the reader with what is missing from most targeted introductions to pathology—the cell biology behind pathophysiology

Illustrated Dictionary of Parasitology in the Post-genomic Era

Author : Hany Elsheikha
Publisher : Caister Academic Press Limited
ISBN 13 : 9781910190678
Total Pages : 0 pages
Book Rating : 4.1/5 (96 download)

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Book Synopsis Illustrated Dictionary of Parasitology in the Post-genomic Era by : Hany Elsheikha

Download or read book Illustrated Dictionary of Parasitology in the Post-genomic Era written by Hany Elsheikha and published by Caister Academic Press Limited. This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: An up-to-date illustrated dictionary of the terminology encountered in contemporary parasitology literature. Concise definitions and explanations of parasitology terms and related molecular processes presented in an easy-to-use, A-Z order with particular emphasis on terms that are of relevance to parasite biotechnology and molecular biology.

Principles of Gender-Specific Medicine

Author : Marianne Legato J
Publisher : Academic Press
ISBN 13 : 0128035420
Total Pages : 794 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Principles of Gender-Specific Medicine by : Marianne Legato J

Download or read book Principles of Gender-Specific Medicine written by Marianne Legato J and published by Academic Press. This book was released on 2017-05-15 with total page 794 pages. Available in PDF, EPUB and Kindle. Book excerpt: The announcement that we had decoded the human genome in 2000 ushered in a new and unique era in biomedical research and clinical medicine. This Third Edition of Principles of Gender-Specific Medicine focuses, as in the past two editions, on the essentials of sexual dimorphism in human physiology and pathophysiology, but emphasizes the latest information about molecular biology and genomic science in a variety of disciplines. Thus, this edition is a departure from the previous two; the editor solicited individual manuscripts from innovative scientists in a variety of fields rather than the traditional arrangement of sections devoted to the various subspecialties of medicine edited by section chiefs. Wherever it was available, these authors incorporated the latest information about the impact of the genome and the elements that modify its expression on human physiology and illness. All chapters progress translationally from basic science to the clinical applications of gender-specific therapy and suggest the most important topics for future investigation. This book is essential reading for all biomedical investigators and medical educators involved in gender-specific medicine. It will also be useful for primary care practitioners who need information about the importance of sex and gender in the prevention, diagnosis and treatment of illness. Winner of the 2018 PROSE Award in Clinical Medicine from the Association of American Publishers! - 2018 PROSE Awards - Winner, Award for Clinical Medicine: Association of American Publishers - Outlines sex-specific differences in normal human function and explains the impact of age, hormones, and environment on the incidence and outcome of illness - Reflects the latest information about the molecular basis of the sexual dimorphism in human physiology and the experience of disease - Reviews the implications of our ever-improving ability to describe the genetic basis of vulnerability to disease and our capacity to alter the genome itself - Illustrates the importance of new NIH guidelines that urge the inclusion of sex as a variable in research protocols

Bioinformatics in the Post-genomic Era

Author : Jeffrey Augen
Publisher : Addison-Wesley Professional
ISBN 13 :
Total Pages : 412 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Bioinformatics in the Post-genomic Era by : Jeffrey Augen

Download or read book Bioinformatics in the Post-genomic Era written by Jeffrey Augen and published by Addison-Wesley Professional. This book was released on 2005 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive treatment of the role of bioinformatics in the emerging world of molecular medicine, for anyone involved in this new field

My Beautiful Genome

Author : Lone Frank
Publisher : Simon and Schuster
ISBN 13 : 1851688641
Total Pages : 325 pages
Book Rating : 4.8/5 (516 download)

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Book Synopsis My Beautiful Genome by : Lone Frank

Download or read book My Beautiful Genome written by Lone Frank and published by Simon and Schuster. This book was released on 2011-09-01 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: Internationally acclaimed science writer Lone Frank swabs up her DNA to provide the first truly intimate account of the new science of consumer-led genomics. She challenges the business mavericks intent on mapping every baby's genome, ponders the consequences of biological fortune-telling, and prods the psychologists who hope to uncover just how much or how little our environment will matter in the new genetic century - a quest made all the more gripping as Frank considers her family's and her own struggles with depression.

Personalized Medicine

Author : Barbara Prainsack
Publisher : NYU Press
ISBN 13 : 1479856908
Total Pages : 287 pages
Book Rating : 4.4/5 (798 download)

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Book Synopsis Personalized Medicine by : Barbara Prainsack

Download or read book Personalized Medicine written by Barbara Prainsack and published by NYU Press. This book was released on 2017-12-19 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inside today's data-driven personalized medicine, and the time, effort, and information required from patients to make it a reality Medicine has been personal long before the concept of “personalized medicine” became popular. Health professionals have always taken into consideration the individual characteristics of their patients when diagnosing, and treating them. Patients have cared for themselves and for each other, contributed to medical research, and advocated for new treatments. Given this history, why has the notion of personalized medicine gained so much traction at the beginning of the new millennium? Personalized Medicine investigates the recent movement for patients’ involvement in how they are treated, diagnosed, and medicated; a movement that accompanies the increasingly popular idea that people should be proactive, well-informed participants in their own healthcare. While it is often the case that participatory practices in medicine are celebrated as instances of patient empowerment or, alternatively, are dismissed as cases of patient exploitation, Barbara Prainsack challenges these views to illustrate how personalized medicine can give rise to a technology-focused individualism, yet also present new opportunities to strengthen solidarity. Facing the future, this book reveals how medicine informed by digital, quantified, and computable information is already changing the personalization movement, providing a contemporary twist on how medical symptoms or ailments are shared and discussed in society. Bringing together empirical work and critical scholarship from medicine, public health, data governance, bioethics, and digital sociology, Personalized Medicine analyzes the challenges of personalization driven by patient work and data. This compelling volume proposes an understanding that uses novel technological practices to foreground the needs and interests of patients, instead of being ruled by them.

Post-Genomic Perspectives in Modeling and Control of Breathing

Author : Jean Champagnat
Publisher : Springer Science & Business Media
ISBN 13 : 038727023X
Total Pages : 330 pages
Book Rating : 4.3/5 (872 download)

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Book Synopsis Post-Genomic Perspectives in Modeling and Control of Breathing by : Jean Champagnat

Download or read book Post-Genomic Perspectives in Modeling and Control of Breathing written by Jean Champagnat and published by Springer Science & Business Media. This book was released on 2010-06-28 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Post Genomic Perspectives in Modeling and Control of Breathing is comprised of the proceedings of the IXth Oxford Conference on Modeling and Control of Breathing, held September 13-16, 2003 in Paris, France. This publication is placed within the general framework of post-genomic neurobiology, pathology, and the precise example of the rhythmic respiratory neural assembly being used to understand how genetic networks have been selected and conserved in the vertebrate brain. Specific topics include: ion channels and synapses responsible for respiratory rhythmogenesis and plasticity; pre- and post-natal development of the respiratory rhythm; chemosensory transduction and chemo-afferent signalling. These valuable insights open new avenues as to why the genetic codes underlying a vital function such as breathing have been selected, conserved, or optimized during evolution – a major issue of post-genomic biology. This critical issue will be considered from both top-down and bottom-up integrative modeling standpoints, with a view to elucidating the functional genomics linking discrete molecules to the integrated system that regulates breathing.

Synthetic

Author : Sophia Roosth
Publisher : University of Chicago Press
ISBN 13 : 022644046X
Total Pages : 258 pages
Book Rating : 4.2/5 (264 download)

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Book Synopsis Synthetic by : Sophia Roosth

Download or read book Synthetic written by Sophia Roosth and published by University of Chicago Press. This book was released on 2017-03 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the final years of the twentieth century, emigres from mechanical and electrical engineering and computer science resolved that if the aim of biology was to understand life, then making life would yield better theories than experimentation. Sophia Roosth, a cultural anthropologist, takes us into the world of these self-named synthetic biologists who, she shows, advocate not experiment but manufacture, not reduction but construction, not analysis but synthesis. Roosth reveals how synthetic biologists make new living things in order to understand better how life works. What we see through her careful questioning is that the biological features, theories, and limits they fasten upon are determined circularly by their own experimental tactics. This is a story of broad interest, because the active, interested making of the synthetic biologists is endemic to the sciences of our time."

Systems Biology

Author : Lilia Alberghina
Publisher : Springer Science & Business Media
ISBN 13 : 9783540742692
Total Pages : 432 pages
Book Rating : 4.7/5 (426 download)

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Book Synopsis Systems Biology by : Lilia Alberghina

Download or read book Systems Biology written by Lilia Alberghina and published by Springer Science & Business Media. This book was released on 2007-10-04 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: For life to be understood and disease to become manageable, the wealth of postgenomic data now needs to be made dynamic. This development requires systems biology, integrating computational models for cells and organisms in health and disease; quantitative experiments (high-throughput, genome-wide, living cell, in silico); and new concepts and principles concerning interactions. This book defines the new field of systems biology and discusses the most efficient experimental and computational strategies. The benefits for industry, such as the new network-based drug-target design validation, and testing, are also presented.

Race in a Bottle

Author : Jonathan Kahn
Publisher : Columbia University Press
ISBN 13 : 0231162987
Total Pages : 330 pages
Book Rating : 4.2/5 (311 download)

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Book Synopsis Race in a Bottle by : Jonathan Kahn

Download or read book Race in a Bottle written by Jonathan Kahn and published by Columbia University Press. This book was released on 2013 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Approved by the FDA in 2005 as the first drug with a race-specific indication on its label, BiDil was touted as a pathbreaking therapy to treat heart failure in black patients. Kahn reveals that, at the most basic level, BiDil became racial through legal maneuvering and commercial pressure as much as through medical understandings of how the drug worked. He examines the legal and calls for a more reasoned approach to using race in biomedical research and practice.

Xenopus Protocols

Author : STEFAN HOPPLER
Publisher : Humana Press
ISBN 13 : 9781493959532
Total Pages : 568 pages
Book Rating : 4.9/5 (595 download)

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Book Synopsis Xenopus Protocols by : STEFAN HOPPLER

Download or read book Xenopus Protocols written by STEFAN HOPPLER and published by Humana Press. This book was released on 2016-08-23 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the 20th century Xenopus has flourished as an accessible experimental model system for studying vertebrate biology. The second edition of Xenopus Protocols:Post-Genomic Approaches expands upon the previous edition with novel approaches inspired by Xenopus tropicalis and the sequencing of its genome. Xenopus tropicalis genomics and tractable genetics combined with the unique experimental advantages of Xenopus laevis and their distinctive phylogenetic position make them unique model systems for vertebrate embryonic development in the 21st century. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Xenopus Protocols: Post-Genomic Approaches, Second Edition provides a toolkit that will enable every laboratory to maximize the power of this extraordinary experimental system in the post-genomic age.