The Organic Chemistry Of Drug Synthesis 4 Volume Set

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The Organic Chemistry of Drug Synthesis, Volume 7

Author : Daniel Lednicer
Publisher : John Wiley & Sons
ISBN 13 : 0470180668
Total Pages : 288 pages
Book Rating : 4.4/5 (71 download)

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Book Synopsis The Organic Chemistry of Drug Synthesis, Volume 7 by : Daniel Lednicer

Download or read book The Organic Chemistry of Drug Synthesis, Volume 7 written by Daniel Lednicer and published by John Wiley & Sons. This book was released on 2007-12-14 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: The classic reference on the synthesis of medicinal agents -- now completely updated The seventh volume in the definitive series that provides a quick yet thorough overview of the synthetic routes used to access specific classesof therapeutic agents, this volume covers approximately 220 new non-proprietary drug entities introduced since the publication of Volume 6. Many of these compounds represent novel structural types firstidentified by sophisticated new cell-based assays. Specifically, a significant number of new antineoplastic and antiviral agents are covered. As in the previous volumes, materials are organized by chemical class and syntheses originate with available starting materials. Organized to make the information accessible, this resource covers disease state, rationale for method of drug therapy, and the biological activities of each compound and preparation. The Organic Chemistry of Drug Synthesis, Volume 7 is a hands-on reference for medicinal and organic chemists, and a great resource for graduate and advanced undergraduate students in organic and medicinal chemistry.

The Organic Chemistry of Drug Design and Drug Action

Author : Richard B. Silverman
Publisher : Elsevier
ISBN 13 : 0080513379
Total Pages : 650 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis The Organic Chemistry of Drug Design and Drug Action by : Richard B. Silverman

Download or read book The Organic Chemistry of Drug Design and Drug Action written by Richard B. Silverman and published by Elsevier. This book was released on 2012-12-02 with total page 650 pages. Available in PDF, EPUB and Kindle. Book excerpt: Standard medicinal chemistry courses and texts are organized by classes of drugs with an emphasis on descriptions of their biological and pharmacological effects. This book represents a new approach based on physical organic chemical principles and reaction mechanisms that allow the reader to extrapolate to many related classes of drug molecules. The Second Edition reflects the significant changes in the drug industry over the past decade, and includes chapter problems and other elements that make the book more useful for course instruction. - New edition includes new chapter problems and exercises to help students learn, plus extensive references and illustrations - Clearly presents an organic chemist's perspective of how drugs are designed and function, incorporating the extensive changes in the drug industry over the past ten years - Well-respected author has published over 200 articles, earned 21 patents, and invented a drug that is under consideration for commercialization

Organic Chemistry

Author : Robert J. Ouellette
Publisher : Academic Press
ISBN 13 : 0128128399
Total Pages : 1058 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Organic Chemistry by : Robert J. Ouellette

Download or read book Organic Chemistry written by Robert J. Ouellette and published by Academic Press. This book was released on 2018-02-03 with total page 1058 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organic Chemistry: Structure, Mechanism, Synthesis, Second Edition, provides basic principles of this fascinating and challenging science, which lies at the interface of physical and biological sciences. Offering accessible language and engaging examples and illustrations, this valuable introduction for the in-depth chemistry course engages students and gives future and new scientists a new approach to understanding, rather than merely memorizing the key concepts underpinning this fundamental area. The book builds in a logical way from chemical bonding to resulting molecular structures, to the corresponding physical, chemical and biological properties of those molecules. The book explores how molecular structure determines reaction mechanisms, from the smallest to the largest molecules—which in turn determine strategies for organic synthesis. The book then describes the synthetic principles which extend to every aspect of synthesis, from drug design to the methods cells employ to synthesize the molecules of which they are made. These relationships form a continuous narrative throughout the book, in which principles logically evolve from one to the next, from the simplest to the most complex examples, with abundant connections between the theory and applications. Featuring in-book solutions and instructor PowerPoint slides, this Second Edition offers an updated and improved option for students in the two-semester course and for scientists who require a high quality introduction or refresher in the subject. - Offers improvements for the two-semester course sequence and valuable updates including two new chapters on lipids and nucleic acids - Features biochemistry and biological examples highlighted throughout the book, making the information relevant and engaging to readers of all backgrounds and interests - Includes a valuable and highly-praised chapter on organometallic chemistry not found in other standard references

The Art of Drug Synthesis

Author : Douglas S. Johnson
Publisher : John Wiley & Sons
ISBN 13 : 111867846X
Total Pages : 295 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis The Art of Drug Synthesis by : Douglas S. Johnson

Download or read book The Art of Drug Synthesis written by Douglas S. Johnson and published by John Wiley & Sons. This book was released on 2013-02-26 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Art of Drug Synthesis illustrates how chemistry, biology, pharmacokinetics, and a host of other disciplines come together to produce successful medicines. The authors have compiled a collection of 21 representative categories of drugs, from which they have selected as examples many of the best-selling drugs on the market today. An introduction to each drug is provided, as well as background to the biology, pharmacology, pharmacokinetics, and drug metabolism, followed by a detailed account of the drug synthesis. Edited by prominent scientists working in drug discovery for Pfizer Meets the needs of a growing community of researchers in pharmaceutical R&D Provides a useful guide for practicing pharmaceutical scientists as well as a text for medicinal chemistry students An excellent follow-up to the very successful first book by these editors, Contemporary Drug Synthesis, but with all new therapeutic categories and drugs discussed.

Burger's Medicinal Chemistry, Drug Discovery and Development, 8 Volume Set

Author :
Publisher : John Wiley & Sons
ISBN 13 : 111953030X
Total Pages : 6057 pages
Book Rating : 4.1/5 (195 download)

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Book Synopsis Burger's Medicinal Chemistry, Drug Discovery and Development, 8 Volume Set by :

Download or read book Burger's Medicinal Chemistry, Drug Discovery and Development, 8 Volume Set written by and published by John Wiley & Sons. This book was released on 2021-04-20 with total page 6057 pages. Available in PDF, EPUB and Kindle. Book excerpt: Burger’s Medicinal Chemistry, Drug Discovery and Development Explore the freshly updated flagship reference for medicinal chemists and pharmaceutical professionals The newly revised eighth edition of the eight-volume Burger’s Medicinal Chemistry, Drug Discovery and Development is the latest installment in this celebrated series covering the entirety of the drug development and discovery process. With the addition of expert editors in each subject area, this eight-volume set adds 35 chapters to the extensive existing chapters. New additions include analyses of opioid addiction treatments, antibody and gene therapy for cancer, blood-brain barrier, HIV treatments, and industrial-academic collaboration structures. Along with the incorporation of practical material on drug hunting, the set features sections on drug discovery, drug development, cardiovascular diseases, metabolic diseases, immunology, cancer, anti-Infectives, and CNS disorders. The text continues the legacy of previous volumes in the series by providing recognized, renowned, authoritative, and comprehensive information in the area of drug discovery and development while adding cutting-edge new material on issues like the use of artificial intelligence in medicinal chemistry. Included: Volume 1: Methods in Drug Discovery, edited by Kent D. Stewart Volume 2: Discovering Lead Molecules, edited by Kent D. Stewart Volume 3: Drug Development, edited by Ramnarayan S. Randad and Michael Myers Volume 4: Cardiovascular, Endocrine, and Metabolic Diseases, edited by Scott D. Edmondson Volume 5: Pulmonary, Bone, Immunology, Vitamins, and Autocoid Therapeutic Agents, edited by Bryan H. Norman Volume 6: Cancer, edited by Barry Gold and Donna M. Huryn Volume 7: Anti-Infectives, edited by Roland E. Dolle Volume 8: CNS Disorders, edited by Richard A. Glennon Perfect for research departments in the pharmaceutical and biotechnology industries, Burger’s Medicinal Chemistry, Drug Discovery and Development can be used by graduate students seeking a one-stop reference for drug development and discovery and deserves its place in the libraries of biomedical research institutes, medical, pharmaceutical, and veterinary schools.

The Organic Chemistry of Drug Synthesis, Volume 5

Author : Daniel Lednicer
Publisher : John Wiley & Sons
ISBN 13 : 9780471589594
Total Pages : 238 pages
Book Rating : 4.5/5 (895 download)

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Book Synopsis The Organic Chemistry of Drug Synthesis, Volume 5 by : Daniel Lednicer

Download or read book The Organic Chemistry of Drug Synthesis, Volume 5 written by Daniel Lednicer and published by John Wiley & Sons. This book was released on 1994-12-13 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Updated every five years, the series represents the optimal compromise between currency and a sufficient body of material for cohesive and comprehensive treatment in a monograph. Provides a quick yet thorough overview of the synthetic routines that have been used to access specific classes of therapeutic agents. Materials are organized by chemical class, and syntheses are taken back to available starting materials. Discusses disease state, rational for method of drug therapy, biological activities of each compound and preparation. Coverage also includes those generic pharmaceutical compounds not accorded clinical status. A glossary defines biological terms.

Contemporary Drug Synthesis

Author : Jie Jack Li
Publisher : John Wiley & Sons
ISBN 13 : 0471686735
Total Pages : 238 pages
Book Rating : 4.4/5 (716 download)

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Book Synopsis Contemporary Drug Synthesis by : Jie Jack Li

Download or read book Contemporary Drug Synthesis written by Jie Jack Li and published by John Wiley & Sons. This book was released on 2004-12-27 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: An integrated and insightful look at successful drug synthesis in today's drug discovery market The pharmaceutical industry is unquestionably vibrant today, with drug synthesis making a vital contribution. Whether in the early developmental stages of identifying and optimizing a lead, or the latter stages of process development and cost-effective scale-up, the ability to design elegant and economical synthetic routes is often a major factor in the eventual viability and commercial success of a drug. Contemporary Drug Synthesis examines how leading researchers and manufacturers have integrated chemistry, biology, pharmacokinetics, and a host of other disciplines in the creation and development of leading drugs. Authored by four of the pharmaceutical industry's most respected scientists, this timely volume: Focuses on the processes that resulted in high-profile drugs including Lipitor, Celebrex, Viagra, Gleevec, Nexium, Claritin, and over a dozen others Provides an in-depth introduction to each drug, followed by a detailed account of its synthesis Organizes the drugs into fourteen therapeutic areas for clarity and ease of use Process chemists provide an essential bridge between chemistry and the marketplace, creating scientifically practical drug processes while never losing sight of the commercial viability of those processes. Contemporary Drug Synthesis meets the needs of a growing community of researchers in pharmaceutical research and development, and is both a useful guide for practicing pharmaceutical scientists and an excellent text for medicinal and organic chemistry students.

Strategies and Tactics in Organic Synthesis

Author : Michael Harmata
Publisher : Academic Press
ISBN 13 : 9780124502840
Total Pages : 522 pages
Book Rating : 4.5/5 (28 download)

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Book Synopsis Strategies and Tactics in Organic Synthesis by : Michael Harmata

Download or read book Strategies and Tactics in Organic Synthesis written by Michael Harmata and published by Academic Press. This book was released on 2004-11-03 with total page 522 pages. Available in PDF, EPUB and Kindle. Book excerpt: This title provides a forum for investigators to discuss their approach to the science and art of organic synthesis in a unique way. There are stories that vividly demonstrate the power of the human endeavour known as organic synthesis and the creativity and tenacity of its practitioners.

Protecting-Group-Free Organic Synthesis

Author : Rodney A. Fernandes
Publisher : John Wiley & Sons
ISBN 13 : 1119295203
Total Pages : 283 pages
Book Rating : 4.1/5 (192 download)

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Book Synopsis Protecting-Group-Free Organic Synthesis by : Rodney A. Fernandes

Download or read book Protecting-Group-Free Organic Synthesis written by Rodney A. Fernandes and published by John Wiley & Sons. This book was released on 2018-08-20 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents a comprehensive account of established protecting-group-free synthetic routes to molecules of medium to high complexity This book supports synthetic chemists in the design of strategies, which avoid or minimize the use of protecting groups so as to come closer to achieving an “ideal synthesis” and back the global need of practicing green chemistry. The only resource of its kind to focus entirely on protecting-group-free synthesis, it is edited by a leading practitioner in the field, and features enlightening contributions by top experts and researchers from across the globe. The introductory chapter includes a concise review of historical developments, and discusses the concepts, need for, and future prospects of protecting-group-free synthesis. Following this, the book presents information on protecting-group-free synthesis of complex natural products and analogues, heterocycles, drugs, and related pharmaceuticals. Later chapters discuss practicing protecting-group-free synthesis using carbohydrates and of glycosyl derivatives, glycol-polymers and glyco-conjugates. The book concludes with a chapter on latent functionality as a tactic toward formal protecting-group-free synthesis. A comprehensive account of established protecting-group-free (PGF) synthetic routes to molecules of medium to high complexity Benefits total synthesis, methodology development and drug synthesis researchers Supports synthetic chemists in the design of strategies, which avoid or minimize the use of protecting groups so as to come closer to achieving an “ideal synthesis” and support the global need of practicing green chemistry Covers a topic that is gaining importance because it renders syntheses more economical Protecting-Group-Free Organic Synthesis: Improving Economy and Efficiency is an important book for academic researchers in synthetic organic chemistry, green chemistry, medicinal and pharmaceutical chemistry, biochemistry, and drug discovery.

Comprehensive Organic Synthesis

Author : Barry M. Trost
Publisher : Elsevier
ISBN 13 : 9780080405995
Total Pages : 1174 pages
Book Rating : 4.4/5 (59 download)

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Book Synopsis Comprehensive Organic Synthesis by : Barry M. Trost

Download or read book Comprehensive Organic Synthesis written by Barry M. Trost and published by Elsevier. This book was released on 1991 with total page 1174 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 8.

Comprehensive Organic Chemistry Experiments for the Laboratory Classroom

Author : Carlos A. M. Afonso
Publisher : Royal Society of Chemistry
ISBN 13 : 1849739633
Total Pages : 976 pages
Book Rating : 4.8/5 (497 download)

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Book Synopsis Comprehensive Organic Chemistry Experiments for the Laboratory Classroom by : Carlos A. M. Afonso

Download or read book Comprehensive Organic Chemistry Experiments for the Laboratory Classroom written by Carlos A. M. Afonso and published by Royal Society of Chemistry. This book was released on 2016-12-16 with total page 976 pages. Available in PDF, EPUB and Kindle. Book excerpt: This expansive and practical textbook contains organic chemistry experiments for teaching in the laboratory at the undergraduate level covering a range of functional group transformations and key organic reactions.The editorial team have collected contributions from around the world and standardized them for publication. Each experiment will explore a modern chemistry scenario, such as: sustainable chemistry; application in the pharmaceutical industry; catalysis and material sciences, to name a few. All the experiments will be complemented with a set of questions to challenge the students and a section for the instructors, concerning the results obtained and advice on getting the best outcome from the experiment. A section covering practical aspects with tips and advice for the instructors, together with the results obtained in the laboratory by students, has been compiled for each experiment. Targeted at professors and lecturers in chemistry, this useful text will provide up to date experiments putting the science into context for the students.

Comprehensive Organic Synthesis

Author :
Publisher : Newnes
ISBN 13 : 008097743X
Total Pages : 9815 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Comprehensive Organic Synthesis by :

Download or read book Comprehensive Organic Synthesis written by and published by Newnes. This book was released on 2014-02-14 with total page 9815 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of Comprehensive Organic Synthesis—winner of the 2015 PROSE Award for Multivolume Reference/Science from the Association of American Publishers—builds upon the highly respected first edition in drawing together the new common themes that underlie the many disparate areas of organic chemistry. These themes support effective and efficient synthetic strategies, thus providing a comprehensive overview of this important discipline. Fully revised and updated, this new set forms an essential reference work for all those seeking information on the solution of synthetic problems, whether they are experienced practitioners or chemists whose major interests lie outside organic synthesis. In addition, synthetic chemists requiring the essential facts in new areas, as well as students completely new to the field, will find Comprehensive Organic Synthesis, Second Edition, Nine Volume Set an invaluable source, providing an authoritative overview of core concepts. Winner of the 2015 PROSE Award for Multivolume Reference/Science from the Association of American Publishers Contains more than170 articles across nine volumes, including detailed analysis of core topics such as bonds, oxidation, and reduction Includes more than10,000 schemes and images Fully revised and updated; important growth areas—including combinatorial chemistry, new technological, industrial, and green chemistry developments—are covered extensively

Sustainable Synthesis of Pharmaceuticals

Author : Mariette M. Pereira
Publisher : Royal Society of Chemistry
ISBN 13 : 1788010655
Total Pages : 300 pages
Book Rating : 4.7/5 (88 download)

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Book Synopsis Sustainable Synthesis of Pharmaceuticals by : Mariette M. Pereira

Download or read book Sustainable Synthesis of Pharmaceuticals written by Mariette M. Pereira and published by Royal Society of Chemistry. This book was released on 2018-03-26 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Organic Chemistry of Sugars

Author : Daniel E. Levy
Publisher : CRC Press
ISBN 13 : 1420027956
Total Pages : 904 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis The Organic Chemistry of Sugars by : Daniel E. Levy

Download or read book The Organic Chemistry of Sugars written by Daniel E. Levy and published by CRC Press. This book was released on 2005-09-21 with total page 904 pages. Available in PDF, EPUB and Kindle. Book excerpt: Intrigued as much by its complex nature as by its outsider status in traditional organic chemistry, the editors of The Organic Chemistry of Sugars compile a groundbreaking resource in carbohydrate chemistry that illustrates the ease at which sugars can be manipulated in a variety of organic reactions. Each chapter contains numerous examples demonst

Click Reactions in Organic Synthesis

Author : Srinivasan Chandrasekaran
Publisher : John Wiley & Sons
ISBN 13 : 3527339167
Total Pages : 360 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Click Reactions in Organic Synthesis by : Srinivasan Chandrasekaran

Download or read book Click Reactions in Organic Synthesis written by Srinivasan Chandrasekaran and published by John Wiley & Sons. This book was released on 2016-09-13 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Endlich ein Buch zu Click-Reaktionen mit Schwerpunkt auf der organischen Synthese. Beschrieben werden das Click-Konzept, die zugrunde liegenden Mechanismen und Hauptanwendungsgebiete. NÜTZLICH: Die Click-Chemie ist ein wirkungsvoller Ansatz, um auf einfache Weise komplexe organische Moleküle aus verfügbaren Ausgangsmaterialien zu erzeugen ? der Traum jedes Organikers. EINZIGARTIGER SCHWERPUNKT: Aufgrund des besonderen Schwerpunkts auf der organischen Synthese ist dieses Buch für jeden Synthesechemiker von hohem Interesse. HILFREICH: Click-Reaktionen sind stereospezifisch, einfach durchzuführen, hoch ergiebig und lassen sich in einfach zu entfernenden oder nicht schädlichen Lösungsmitteln durchführen. INTERDISZIPLINÄR: Das Click-Konzept ist bei der Herstellung natürlicher Produkte, bioaktiver Verbindungen, von Kohlenhydraten, Arzneimitteln, Polymeren, supramolekularer Strukturen und Materialien weit verbreitet.

Organic Chemistry

Author : David R. Klein
Publisher : John Wiley & Sons
ISBN 13 : 111944425X
Total Pages : 1312 pages
Book Rating : 4.1/5 (194 download)

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Book Synopsis Organic Chemistry by : David R. Klein

Download or read book Organic Chemistry written by David R. Klein and published by John Wiley & Sons. This book was released on 2017-08-14 with total page 1312 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Organic Chemistry, 3rd Edition, Dr. David Klein builds on the phenomenal success of the first two editions, which presented his unique skills-based approach to learning organic chemistry. Dr. Klein’s skills-based approach includes all of the concepts typically covered in an organic chemistry textbook, and places special emphasis on skills development to support these concepts. This emphasis on skills development in unique SkillBuilder examples provides extensive opportunities for two-semester Organic Chemistry students to develop proficiency in the key skills necessary to succeed in organic chemistry.

Steroid Chemistry at a Glance

Author : Daniel Lednicer
Publisher : John Wiley & Sons
ISBN 13 : 111995729X
Total Pages : 154 pages
Book Rating : 4.1/5 (199 download)

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Book Synopsis Steroid Chemistry at a Glance by : Daniel Lednicer

Download or read book Steroid Chemistry at a Glance written by Daniel Lednicer and published by John Wiley & Sons. This book was released on 2011-06-20 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: The term steroid has become virtually synonymous with drug abuse in sport to the majority of the public. However these steroids - androgens - actually comprise only a single relatively small class of biologically active steroids, and are overshadowed by a large collection of compounds, a sizeable number of which are commercial drugs that share the same structural carbon skeleton. The development of these drugs has led to a large body of organic chemistry often denoted as "Steroid Chemistry". Steroid Chemistry At A Glance provides a concise overview of the main principles and reactions of steroid chemistry. Topics covered include: history, isolation and structure determination of steroids steroid nomenclature and stereochemistry natural sources of steroids synthesis and reactions of aromatic a-ring steroids, androstanes, and pregnanes steroids with a spirolactone at position 17 steroids with hetrocyclic ring A compounds derived from cholesterol Based on the highly successful and student friendly "at a glance" approach, the information is presented in integrated, self contained double page spreads of text and illustrative material. Students of chemistry and pharmacy using Steroid Chemistry at a Glance will find they have a resource with which they can quickly, concisely and confidently acquire, regularly review and revise the basic facts that underpin the properties, synthesis and reactions of this important class of natural products. It will also serve as a handy bench reference for postgraduates and professional chemists.