The Organic Chemistry Of Drug Synthesis

Download The Organic Chemistry Of Drug Synthesis full books in PDF, epub, and Kindle. Read online The Organic Chemistry Of Drug Synthesis ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!

The Organic Chemistry of Drug Synthesis, Volume 7

Author : Daniel Lednicer
Publisher : John Wiley & Sons
ISBN 13 : 0470180668
Total Pages : 288 pages
Book Rating : 4.4/5 (71 download)

DOWNLOAD NOW!

Book Synopsis The Organic Chemistry of Drug Synthesis, Volume 7 by : Daniel Lednicer

Download or read book The Organic Chemistry of Drug Synthesis, Volume 7 written by Daniel Lednicer and published by John Wiley & Sons. This book was released on 2007-12-14 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: The classic reference on the synthesis of medicinal agents -- now completely updated The seventh volume in the definitive series that provides a quick yet thorough overview of the synthetic routes used to access specific classesof therapeutic agents, this volume covers approximately 220 new non-proprietary drug entities introduced since the publication of Volume 6. Many of these compounds represent novel structural types firstidentified by sophisticated new cell-based assays. Specifically, a significant number of new antineoplastic and antiviral agents are covered. As in the previous volumes, materials are organized by chemical class and syntheses originate with available starting materials. Organized to make the information accessible, this resource covers disease state, rationale for method of drug therapy, and the biological activities of each compound and preparation. The Organic Chemistry of Drug Synthesis, Volume 7 is a hands-on reference for medicinal and organic chemists, and a great resource for graduate and advanced undergraduate students in organic and medicinal chemistry.

The Organic Chemistry of Drug Synthesis, Volume 2

Author : Daniel Lednicer
Publisher : John Wiley & Sons
ISBN 13 : 9780471043928
Total Pages : 562 pages
Book Rating : 4.0/5 (439 download)

DOWNLOAD NOW!

Book Synopsis The Organic Chemistry of Drug Synthesis, Volume 2 by : Daniel Lednicer

Download or read book The Organic Chemistry of Drug Synthesis, Volume 2 written by Daniel Lednicer and published by John Wiley & Sons. This book was released on 1980-05-13 with total page 562 pages. Available in PDF, EPUB and Kindle. Book excerpt: Updated every five years, the series represents the optimal compromise between currency and a sufficient body of material for cohesive and comprehensive treatment in a monograph. Provides a quick yet thorough overview of the synthetic routines that have been used to access specific classes of therapeutic agents. Materials are organized by chemical class, and syntheses are taken back to available starting materials. Discusses disease state, rational for method of drug therapy, biological activities of each compound and preparation. Coverage also includes those generic pharmaceutical compounds not accorded clinical status. A glossary defines biological terms.

Strategies for Organic Drug Synthesis and Design

Author : Daniel Lednicer
Publisher : John Wiley & Sons
ISBN 13 : 9780470399590
Total Pages : 700 pages
Book Rating : 4.3/5 (995 download)

DOWNLOAD NOW!

Book Synopsis Strategies for Organic Drug Synthesis and Design by : Daniel Lednicer

Download or read book Strategies for Organic Drug Synthesis and Design written by Daniel Lednicer and published by John Wiley & Sons. This book was released on 2009-03-04 with total page 700 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines and evaluates the strategies utilized to design and synthesize pharmaceutically active agents. Significant updates over the last 10 years since the publication of the 1st edition include synthesis of enantiomerically pure isomers, novel chemical methodologies, and new pharmaceutical agents targeted at novel biological endpoints. Written by an experienced successful author, this book meets the needs of a growing community of researchers in pharmaceutical R &D, as well as medical professionals, by providing a useful guide for designing and synthesizing pharmaceutical agents. Additionally, it is a useful text for medicinal chemistry students.

The Organic Chemistry of Drug Design and Drug Action

Author : Richard B. Silverman
Publisher : Elsevier
ISBN 13 : 0080513379
Total Pages : 650 pages
Book Rating : 4.0/5 (85 download)

DOWNLOAD NOW!

Book Synopsis The Organic Chemistry of Drug Design and Drug Action by : Richard B. Silverman

Download or read book The Organic Chemistry of Drug Design and Drug Action written by Richard B. Silverman and published by Elsevier. This book was released on 2012-12-02 with total page 650 pages. Available in PDF, EPUB and Kindle. Book excerpt: Standard medicinal chemistry courses and texts are organized by classes of drugs with an emphasis on descriptions of their biological and pharmacological effects. This book represents a new approach based on physical organic chemical principles and reaction mechanisms that allow the reader to extrapolate to many related classes of drug molecules. The Second Edition reflects the significant changes in the drug industry over the past decade, and includes chapter problems and other elements that make the book more useful for course instruction. - New edition includes new chapter problems and exercises to help students learn, plus extensive references and illustrations - Clearly presents an organic chemist's perspective of how drugs are designed and function, incorporating the extensive changes in the drug industry over the past ten years - Well-respected author has published over 200 articles, earned 21 patents, and invented a drug that is under consideration for commercialization

An Introduction to Drug Synthesis

Author : Graham L. Patrick
Publisher : Oxford University Press, USA
ISBN 13 : 0198708432
Total Pages : 587 pages
Book Rating : 4.1/5 (987 download)

DOWNLOAD NOW!

Book Synopsis An Introduction to Drug Synthesis by : Graham L. Patrick

Download or read book An Introduction to Drug Synthesis written by Graham L. Patrick and published by Oxford University Press, USA. This book was released on 2015 with total page 587 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction to Drug Synthesis explores the central role played by organic synthesis in the process of drug design and development - from the generation of novel drug structures to the improved efficiency of large scale synthesis.

The Organic Chemistry of Drug Design and Drug Action

Author : Richard B. Silverman
Publisher : Academic Press
ISBN 13 : 0123820316
Total Pages : 537 pages
Book Rating : 4.1/5 (238 download)

DOWNLOAD NOW!

Book Synopsis The Organic Chemistry of Drug Design and Drug Action by : Richard B. Silverman

Download or read book The Organic Chemistry of Drug Design and Drug Action written by Richard B. Silverman and published by Academic Press. This book was released on 2014-03-29 with total page 537 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Organic Chemistry of Drug Design and Drug Action, Third Edition, represents a unique approach to medicinal chemistry based on physical organic chemical principles and reaction mechanisms that rationalize drug action, which allows reader to extrapolate those core principles and mechanisms to many related classes of drug molecules. This new edition includes updates to all chapters, including new examples and references. It reflects significant changes in the process of drug design over the last decade and preserves the successful approach of the previous editions while including significant changes in format and coverage. This text is designed for undergraduate and graduate students in chemistry studying medicinal chemistry or pharmaceutical chemistry; research chemists and biochemists working in pharmaceutical and biotechnology industries. - Updates to all chapters, including new examples and references - Chapter 1 (Introduction): Completely rewritten and expanded as an overview of topics discussed in detail throughout the book - Chapter 2 (Lead Discovery and Lead Modification): Sections on sources of compounds for screening including library collections, virtual screening, and computational methods, as well as hit-to-lead and scaffold hopping; expanded sections on sources of lead compounds, fragment-based lead discovery, and molecular graphics; and deemphasized solid-phase synthesis and combinatorial chemistry - Chapter 3 (Receptors): Drug-receptor interactions, cation-p and halogen bonding; atropisomers; case history of the insomnia drug suvorexant - Chapter 4 (Enzymes): Expanded sections on enzyme catalysis in drug discovery and enzyme synthesis - Chapter 5 (Enzyme Inhibition and Inactivation): New case histories: - for competitive inhibition, the epidermal growth factor receptor tyrosine kinase inhibitor, erlotinib and Abelson kinase inhibitor, imatinib - for transition state analogue inhibition, the purine nucleoside phosphorylase inhibitors, forodesine and DADMe-ImmH, as well as the mechanism of the multisubstrate analog inhibitor isoniazid - for slow, tight-binding inhibition, the dipeptidyl peptidase-4 inhibitor, saxagliptin - Chapter 7 (Drug Resistance and Drug Synergism): This new chapter includes topics taken from two chapters in the previous edition, with many new examples - Chapter 8 (Drug Metabolism): Discussions of toxicophores and reactive metabolites - Chapter 9 (Prodrugs and Drug Delivery Systems): Discussion of antibody–drug conjugates

The Organic Chemistry of Drug Design and Drug Action

Author : Richard B. Silverman
Publisher : Academic Press
ISBN 13 : 9780126437324
Total Pages : 660 pages
Book Rating : 4.4/5 (373 download)

DOWNLOAD NOW!

Book Synopsis The Organic Chemistry of Drug Design and Drug Action by : Richard B. Silverman

Download or read book The Organic Chemistry of Drug Design and Drug Action written by Richard B. Silverman and published by Academic Press. This book was released on 2004-01-12 with total page 660 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug discovery, design and development. Receptors. Enzymes. Enzyme inhibition and inactivation. DNA-interactive agents. Drug metabolism. Prodrugs and drug delivery systems.

Drug Synthesis Book Set

Author : Jie Jack Li
Publisher : John Wiley & Sons
ISBN 13 : 9781119185659
Total Pages : 0 pages
Book Rating : 4.1/5 (856 download)

DOWNLOAD NOW!

Book Synopsis Drug Synthesis Book Set by : Jie Jack Li

Download or read book Drug Synthesis Book Set written by Jie Jack Li and published by John Wiley & Sons. This book was released on 2015-11-23 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This set presents the authoritative and acclaimed Drug Synthesis books edited by Jie Jack Li and Douglas Johnson: Contemporary Drug Synthesis, The Art of Drug Synthesis, Modern Drug Synthesis, and Innovative Drug Synthesis. This book set will be enormously useful to pharmaceutical industry labs, research scientists in lead optimization and process development, and graduate students and courses in organic chemistry, synthetic organic chemistry, heterocyclic chemistry, medicinal chemistry, and drug synthesis courses.

The Organic Chemistry of Drug Synthesis, 6 Volume Set

Author : Daniel Lednicer
Publisher : Wiley-Interscience
ISBN 13 : 9780471333708
Total Pages : 0 pages
Book Rating : 4.3/5 (337 download)

DOWNLOAD NOW!

Book Synopsis The Organic Chemistry of Drug Synthesis, 6 Volume Set by : Daniel Lednicer

Download or read book The Organic Chemistry of Drug Synthesis, 6 Volume Set written by Daniel Lednicer and published by Wiley-Interscience. This book was released on 1998-11-18 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Updated every five years, the series represents the optimal compromise between currency and a sufficient body of material for cohesive and comprehensive treatment in a monograph. Provides a quick yet thorough overview of the synthetic routines that have been used to access specific classes of therapeutic agents. Materials are organized by chemical class, and syntheses are taken back to available starting materials. Discusses disease state, rational for method of drug therapy, biological activities of each compound and preparation. Coverage also includes those generic pharmaceutical compounds not accorded clinical status. A glossary defines biological terms.

The Art of Drug Synthesis

Author : Douglas S. Johnson
Publisher : John Wiley & Sons
ISBN 13 : 111867846X
Total Pages : 295 pages
Book Rating : 4.1/5 (186 download)

DOWNLOAD NOW!

Book Synopsis The Art of Drug Synthesis by : Douglas S. Johnson

Download or read book The Art of Drug Synthesis written by Douglas S. Johnson and published by John Wiley & Sons. This book was released on 2013-02-26 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Art of Drug Synthesis illustrates how chemistry, biology, pharmacokinetics, and a host of other disciplines come together to produce successful medicines. The authors have compiled a collection of 21 representative categories of drugs, from which they have selected as examples many of the best-selling drugs on the market today. An introduction to each drug is provided, as well as background to the biology, pharmacology, pharmacokinetics, and drug metabolism, followed by a detailed account of the drug synthesis. Edited by prominent scientists working in drug discovery for Pfizer Meets the needs of a growing community of researchers in pharmaceutical R&D Provides a useful guide for practicing pharmaceutical scientists as well as a text for medicinal chemistry students An excellent follow-up to the very successful first book by these editors, Contemporary Drug Synthesis, but with all new therapeutic categories and drugs discussed.

The Organic Chemistry of Drug Synthesis, Volume 5

Author : Daniel Lednicer
Publisher : John Wiley & Sons
ISBN 13 : 9780471589594
Total Pages : 238 pages
Book Rating : 4.5/5 (895 download)

DOWNLOAD NOW!

Book Synopsis The Organic Chemistry of Drug Synthesis, Volume 5 by : Daniel Lednicer

Download or read book The Organic Chemistry of Drug Synthesis, Volume 5 written by Daniel Lednicer and published by John Wiley & Sons. This book was released on 1994-12-13 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Updated every five years, the series represents the optimal compromise between currency and a sufficient body of material for cohesive and comprehensive treatment in a monograph. Provides a quick yet thorough overview of the synthetic routines that have been used to access specific classes of therapeutic agents. Materials are organized by chemical class, and syntheses are taken back to available starting materials. Discusses disease state, rational for method of drug therapy, biological activities of each compound and preparation. Coverage also includes those generic pharmaceutical compounds not accorded clinical status. A glossary defines biological terms.

The Organic Chemistry of Drug Synthesis

Author : Daniel Lednicer
Publisher : Wiley-VCH
ISBN 13 : 9780841225237
Total Pages : 350 pages
Book Rating : 4.2/5 (252 download)

DOWNLOAD NOW!

Book Synopsis The Organic Chemistry of Drug Synthesis by : Daniel Lednicer

Download or read book The Organic Chemistry of Drug Synthesis written by Daniel Lednicer and published by Wiley-VCH. This book was released on 1993-10-15 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Organic Chemistry of Drug Synthesis, 4 Volume Set

Author : Daniel Lednicer
Publisher : Wiley-Interscience
ISBN 13 : 9780471531760
Total Pages : 0 pages
Book Rating : 4.5/5 (317 download)

DOWNLOAD NOW!

Book Synopsis The Organic Chemistry of Drug Synthesis, 4 Volume Set by : Daniel Lednicer

Download or read book The Organic Chemistry of Drug Synthesis, 4 Volume Set written by Daniel Lednicer and published by Wiley-Interscience. This book was released on 1991-01-16 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Updated every five years, the series represents the optimal compromise between currency and a sufficient body of material for cohesive and comprehensive treatment in a monograph. Provides a quick yet thorough overview of the synthetic routines that have been used to access specific classes of therapeutic agents. Materials are organized by chemical class, and syntheses are taken back to available starting materials. Discusses disease state, rational for method of drug therapy, biological activities of each compound and preparation. Coverage also includes those generic pharmaceutical compounds not accorded clinical status. A glossary defines biological terms.

Organic Chemistry of Drug Degradation

Author : Min Li
Publisher : Royal Society of Chemistry
ISBN 13 : 1849734216
Total Pages : 311 pages
Book Rating : 4.8/5 (497 download)

DOWNLOAD NOW!

Book Synopsis Organic Chemistry of Drug Degradation by : Min Li

Download or read book Organic Chemistry of Drug Degradation written by Min Li and published by Royal Society of Chemistry. This book was released on 2012 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines drug degradation pathways with an emphasis on the underlying chemical mechanisms.

Contemporary Drug Synthesis

Author : Jie Jack Li
Publisher : John Wiley & Sons
ISBN 13 : 0471686735
Total Pages : 238 pages
Book Rating : 4.4/5 (716 download)

DOWNLOAD NOW!

Book Synopsis Contemporary Drug Synthesis by : Jie Jack Li

Download or read book Contemporary Drug Synthesis written by Jie Jack Li and published by John Wiley & Sons. This book was released on 2004-12-27 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: An integrated and insightful look at successful drug synthesis in today's drug discovery market The pharmaceutical industry is unquestionably vibrant today, with drug synthesis making a vital contribution. Whether in the early developmental stages of identifying and optimizing a lead, or the latter stages of process development and cost-effective scale-up, the ability to design elegant and economical synthetic routes is often a major factor in the eventual viability and commercial success of a drug. Contemporary Drug Synthesis examines how leading researchers and manufacturers have integrated chemistry, biology, pharmacokinetics, and a host of other disciplines in the creation and development of leading drugs. Authored by four of the pharmaceutical industry's most respected scientists, this timely volume: Focuses on the processes that resulted in high-profile drugs including Lipitor, Celebrex, Viagra, Gleevec, Nexium, Claritin, and over a dozen others Provides an in-depth introduction to each drug, followed by a detailed account of its synthesis Organizes the drugs into fourteen therapeutic areas for clarity and ease of use Process chemists provide an essential bridge between chemistry and the marketplace, creating scientifically practical drug processes while never losing sight of the commercial viability of those processes. Contemporary Drug Synthesis meets the needs of a growing community of researchers in pharmaceutical research and development, and is both a useful guide for practicing pharmaceutical scientists and an excellent text for medicinal and organic chemistry students.

Applied Organic Chemistry

Author : Surya K. De
Publisher : John Wiley & Sons
ISBN 13 : 352782815X
Total Pages : 856 pages
Book Rating : 4.5/5 (278 download)

DOWNLOAD NOW!

Book Synopsis Applied Organic Chemistry by : Surya K. De

Download or read book Applied Organic Chemistry written by Surya K. De and published by John Wiley & Sons. This book was released on 2020-12-07 with total page 856 pages. Available in PDF, EPUB and Kindle. Book excerpt: An indispensable guide for all synthetic chemists who want to learn about the most relevant reactions and reagents employed to synthesize important heterocycles and drugs! The synthesis of natural products, bioactive compounds, pharmaceuticals, and drugs is of fundamental interest in modern organic chemistry. New reagents and reaction methods towards these molecules are being constantly developed. By understanding the mechanisms involved and scope and limitations of each reaction applied, organic chemists can further improve existing reaction protocols and develop novel efficient synthetic routes towards frequently used drugs, such as Aspirin or Penicillin. Applied Organic Chemistry provides a summary of important (name) reactions and reagents applied in modern organic chemistry and drug synthesis. It covers rearrangement, condensation, olefination, metathesis, aromatic electrophilic substitutions, Pd-catalyzed C-C bond forming reactions, multi-component reactions, as well as oxidations and reductions. Each chapter is clearly structured, providing valuable information on reaction details, step-by-step mechanism, experimental procedures, applications, and (patent) references. By providing mechanistic information and representative experimental procedures, this book is an indispensable guide for researchers and professionals in organic chemistry, natural product synthesis, pharmaceutical, and medicinal chemistry, as well as post-graduates preparing themselves for a job in the pharmaceutical industry. Hot Topic: Reviews important classes of organic reactions (incl. name reactions) and reagents in medicinal chemistry. Useful: Provides information on reaction details, common reagents, and functional group transformations used to synthesize natural products, bioactive compounds, drugs, and pharmaceuticals, e.g. Aspirin, Penicillin. Unique: For every reaction the mechanism is explained step by step, and representative experimental procedures are given, unlike most books in this area. User-friendly: Chapters are clearly structured making it easy for the reader to compare different reactions. Applied Organic Chemistry is an indispensable guide for researchers and professionals in organic chemistry, natural product synthesis, pharmaceutical, and medicinal chemistry, as well as post-graduates preparing themselves for a job in the pharmaceutical industry.

Exercises in Organic Synthesis Based on Synthetic Drugs

Author : Marcus Vinícius Nora de Souza
Publisher : Bentham Science Publishers
ISBN 13 : 9811487545
Total Pages : 250 pages
Book Rating : 4.8/5 (114 download)

DOWNLOAD NOW!

Book Synopsis Exercises in Organic Synthesis Based on Synthetic Drugs by : Marcus Vinícius Nora de Souza

Download or read book Exercises in Organic Synthesis Based on Synthetic Drugs written by Marcus Vinícius Nora de Souza and published by Bentham Science Publishers. This book was released on 2020-12-23 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: Exercises in Organic Synthesis Based on Synthetic Drugs presents information on topics about the synthesis of biologically active compounds which are used against a range of diseases in both humans and animals. Topics are supplemented by notes and exercises for students to stimulate inquiry and learning in the academic environment. Readers will be equipped with basic knowledge of synthetic techniques used in organic chemistry and pharmaceutical research and development. Key Features: - Presents information about different techniques and strategies for the synthesis of organic compounds - Covers a broad range of biologically active compounds - Easy to read topical presentation - Exercises, with answers, designed for improving concepts in organic synthesis and medicinal chemistry - Wide range of bibliographic references for further reading and exercises presented, Exercises in Organic Synthesis Based on Synthetic Drugs is an essential textbook for students in beginner level courses in organic chemistry, organic synthesis and medicinal chemistry.