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The Olivo Cerebellar System
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Book Synopsis The olivo-cerebellar system by : Egidio D'Angelo
Download or read book The olivo-cerebellar system written by Egidio D'Angelo and published by Frontiers Media SA. This book was released on 2016-04-29 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the last decades, investigations on the olivo-cerebellar system have attained a high level of sophistication, which led to redefinitions of several structural and functional properties of neurons, synapses, connections and circuits. Research has expanded and deepened in so many directions and so many theories and models have been proposed that an ensemble review of the matter is now needed. Yet, hot topics remain open and scientific discussion is very lively at several fronts. One major question, here as well as in other major brain circuits, is how single neurons and synaptic properties emerge at the network level and contribute to behavioural regulation via neuronal plasticity. Other major aspects that this Research Topic covers and discusses include the development and circuit organization of the olivo-cerebellar network, the established and recent theories of learning and motor control, and the emerging role of the cerebellum in cognitive processing. By touching on such varied and encompassing subjects, this Frontiers Special Topic aims to highlight the state of the art and stimulate future research. We hope that this unique collection of high-quality articles from experts in the field will provide scientists with a powerful basis of knowledge and inspiration to enucleate the major issues deserving further attention.
Download or read book The Olivo-cerebellar System written by and published by . This book was released on 2016 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the last decades, investigations on the olivo-cerebellar system have attained a high level of sophistication, which led to redefinitions of several structural and functional properties of neurons, synapses, connections and circuits. Research has expanded and deepened in so many directions and so many theories and models have been proposed that an ensemble review of the matter is now needed. Yet, hot topics remain open and scientific discussion is very lively at several fronts. One major question, here as well as in other major brain circuits, is how single neurons and synaptic properties emerge at the network level and contribute to behavioural regulation via neuronal plasticity. Other major aspects that this Research Topic covers and discusses include the development and circuit organization of the olivo-cerebellar network, the established and recent theories of learning and motor control, and the emerging role of the cerebellum in cognitive processing. By touching on such varied and encompassing subjects, this Frontiers Special Topic aims to highlight the state of the art and stimulate future research. We hope that this unique collection of high-quality articles from experts in the field will provide scientists with a powerful basis of knowledge and inspiration to enucleate the major issues deserving further attention.
Book Synopsis The Olivocerebellar System in Motor Control by : Piergiorgio Strata
Download or read book The Olivocerebellar System in Motor Control written by Piergiorgio Strata and published by Springer. This book was released on 1989-01-01 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume offers up-to-date reviews on different aspects of the olivocerebellar system. The latest research results are presented on morphological organization, development of afferent and efferent connections, neurotransmitters, and general electrophysiology. The possible part played in the dynamic control of movements and in motor learning and memory is discussed with theoretical models and some clinical problems. The reader has access in one volume to all studies currently being conducted and to the sometimes controversial views on the role of the inferior olive in cerebellar function and motor control.
Book Synopsis The Olivocerebellar System in Motor Control by : Piergiorgio Strata
Download or read book The Olivocerebellar System in Motor Control written by Piergiorgio Strata and published by Springer. This book was released on 2012-07-17 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recently, the role of the olivocerebellar projection in cerebellar operation has drawn the attention of many scientists who are trying to understand how the cerebellum controls movements. The papers published in this book were presented at a meeting held in Turin on August 9-12, 1987 as a satellite symposium of the 2nd World IBRO Congress in Budapest. It was planned in collaboration with Rodolfo Llinas and Masao Ito, although the latter was not able to attend. Some of the papers are in the form of reviews, others are short communications of new unpublished results. All aspects of research on the inferior olive are covered including morphology, neurotransmission, development, and electrophysiology, as well as its relation to behaviour and to human pathology. The lively, endless scientific discussions have not been published, but the reader may well imagine them from the different and sometimes contrasting pOints of views expressed in the papers. There are many examples showing that integrity of the inferior olive is necessary for some forms of motor learning and for the adaptive capabilities ofthe motor system. On the other hand, there is evidence that the inferior olive is important in controlling the dynamic characteristics of movement, both as a phasic and as a tonic operator. From this, two main viewpoints have emerged. The "plasticitists" attribute the role of inducing plastic changes to the synapse between the climbing fibre and the Purkinje cell.
Book Synopsis Olivocerebellar Projection by : A. Brodal
Download or read book Olivocerebellar Projection written by A. Brodal and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 265 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years the inferior olive and its projection to the cerebellum have attracted considerable interest. Numerous experimental anatomic and electrophysiologic studies have been undertaken, and much new information has been brought forward. Many apparently discordant observations have been reported however, and on many points the data obtained by the use of different methbds and approaches appear to be diffi cult to reconcile. Much of the interest in the olivocerebellar projection concerns the topographical localization within the projection. Particularly as a result of research in recent years the pattern of localization has turned out to be far more complex than previously be lieved. It was found useful, therefore, to attempt a review of the subject in the hope that a critical analysis of available observations might make it possible to obtain an integrated picture of the olivocerebellar projection and perhaps fmd some basic principles in the organization of this fiber system. As will be seen, our attempt has been only partly successful. There are still riddles that remain to be solved. In the present review attention will be focused on problems related to the locali zation within the olivocerebellar projection, particularly its anatomic aspects. An extensive review of the physiology of the inferior olive has been published recently by Armstrong (1974), who considers some anatomicophysiologic correlations as well. Physiologic fmdings will be referred to here mainly in relation to our main theme.
Book Synopsis Essentials of Cerebellum and Cerebellar Disorders by : Donna L. Gruol
Download or read book Essentials of Cerebellum and Cerebellar Disorders written by Donna L. Gruol and published by Springer. This book was released on 2016-11-22 with total page 656 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essentials of the Cerebellum and Cerebellar Disorders is the first book of its kind written specifically for graduate students and clinicians. It is based on the 4-volume treatise, Handbook of the Cerebellum and Cerebellar Disorders (Springer, 2013), the definitive reference for scientists and neurologists in the field of cerebellar neurobiology. There have been fundamental advances in the basic science and clinical neurology of the cerebellum and its role in sensorimotor function and cognition. This monograph makes this large and expanding body of knowledge readily accessible to trainees and clinicians alike. The editors are world leaders in the field, and the chapters are authored by an international panel of experts drawn from ataxia clinics and cerebellar laboratories throughout North America, Europe and Asia. Essentials provides a solid grounding in the field of cerebellar research and ataxiology from cerebellar circuity to clinical practice, and it serves as a springboard to a deeper appreciation of both the principles and the complexities of cerebellar neurobiology. Clinicians are expected to have a deep appreciation of cerebellar disorders, not only in specialized ataxia clinics but also in adult and pediatric neurology, neurosurgery, psychiatry and neuropsychology practices, and in outpatient and inpatient rehabilitation settings. This book is an indispensable resource for students and practitioners navigating the evolving field of cerebellar motor and cognitive neurology. It also links to the more expansive Handbook for those who need to explore the topics in this monograph in greater depth.
Book Synopsis Inverse Control by Mirroring Joint Dynamics Within the Olivo-cerebellar Complex by : Rodrigo Alvarez Icaza Rivera
Download or read book Inverse Control by Mirroring Joint Dynamics Within the Olivo-cerebellar Complex written by Rodrigo Alvarez Icaza Rivera and published by Stanford University. This book was released on 2011 with total page 114 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this dissertation, I revisit Kawato's proposal, that the cerebellum predictively modulates descending motor commands, to achieve smooth and coordinated motion, by acquiring an inverse model of the biomechanical plant, and extend it by describing a novel and precise mapping between a cerebellar multizonal microcomplex and a joint's inverse model. This mapping renders two novel predictions: First, inferior olive's oscillations mirror the biomechanical joint's oscillations. Second, deep cerebellar neurons implement a gain factor, set by Purkinje cell inhibition, on inferior olive's signals to mirror the spinal cord's gain. I use biophysical modeling to show that oscillations within the inferior olive match the range of natural frequencies and damping ratios of biophysical joints, and that deep cerebellar neurons enable a multiplicative interaction between the Purkinje and the olivary pathways. Furthermore, I determine the effects of current injection into the inferior olive and the deep cerebellar nuclei and use these results within a control theory model to predict that experimentally disturbing the inferior olive will introduce motor output ringing, while disturbing the deep nuclei will also scale motor output. In both cases, manipulating the inverse model implemented by microzonal microcomplex will unmask the joint's natural dynamics as observed by motor ringing at the joint's natural frequency.
Book Synopsis Handbook of the Cerebellum and Cerebellar Disorders by : Mario Manto
Download or read book Handbook of the Cerebellum and Cerebellar Disorders written by Mario Manto and published by Springer. This book was released on 2012-08-04 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our knowledge of cerebellar functions and cerebellar disorders, called ataxias, is increasing considerably. Studies of the cerebellum are now a central focus in neuroscience. During the last four decades, many laboratories worldwide have dedicated their research activities to understanding the roles of the cerebellum in motor control, cognitive processes and biology of mental processes, behavioral symptoms, and emotion. It is now accepted that the cerebellum acts as a cognitive operator in learning, perception, and attention. Moreover, major improvements in our assessment of in vivo cerebellar architecture using imaging techniques have occurred. A typical example is the accurate description of cerebellar anatomy during fetal development with MRI, a progress which has direct impacts on patient care. These advances have been associated with discoveries of new clinical disorders, in particular in the field of genetic ataxias. More than 20 new genes have been identified these last 10 years. Only for dominant ataxias, more than 30 diseases have now been unravelled. The number of ataxic disorders will increase with aging, the cerebellum being the structure of the brain with the most important loss of neurons with age. More than 300 different cerebellar disorders are encountered during daily practice, but we are missing a single source of information explaining their pathogenesis. Despite the immense amount of knowledge acquired about the cerebellar circuitry these last years, a large book covering the neuroscience of the cerebellum is missing. The goal of this endeavour is to bring up to date information relevant for basic science and also for clinical activities. To reach this goal, the most renowned authors are gathered in a unique and in-depth book with a format of a handbook. We emphasize the connections between molecular findings, imaging features, behavioural/neuropsychological aspects, and clinical implications.
Book Synopsis Distributed Networks - New Outlooks on Cerebellar Function by : Thomas C Watson
Download or read book Distributed Networks - New Outlooks on Cerebellar Function written by Thomas C Watson and published by Frontiers Media SA. This book was released on 2015-07-03 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt: Accumulating evidence suggests that the cerebellum subserves functions beyond the sensorimotor realm. This possibility has received considerable attention during the past quarter century, with recent findings revealing putative cerebellar roles in cognition, emotion and spatial navigation. These functions are potentially underpinned by the behaviour-dependent formation of functional networks in which the cerebellum forms one node of distributed circuits spanning thalamic, limbic and neocortical regions. However, these views are not universally accepted. Therefore, the over-arching aim of this Research Topic was to provide a forum through which the debate on the role of cerebellar interactions with motor and "non-motor" structures can be pursued in a rigorous manner. In particular, we aimed to bring together findings from the clinical, animal, theoretical and neuroimaging fields.
Book Synopsis Creating Coordination in the Cerebellum by : Chris I. De Zeeuw
Download or read book Creating Coordination in the Cerebellum written by Chris I. De Zeeuw and published by Elsevier. This book was released on 2004-12-11 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: Creating Coordination in the Cerebellum provides a multidisciplinary collection of chapters on the cerebellum with topics covering the entire spectrum from development and molecular neurobiology, cell physiology and plasticity to motor control, system physiology, functional imaging and pathology. The book not only presents novel discoveries obtained with recently developed technologies, but also gives new general concepts in global issues of cerebellar development and functions. By doing so it sets the standard for cerebellar research of the 21st century. * Provides a complete overview of current cerebellar research * Includes color illustrations * Contains contributions from renowned cerebellar scientists
Book Synopsis Cerebellar Functions by : J. Bloedel
Download or read book Cerebellar Functions written by J. Bloedel and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past few semesters a group of neurologists, neurophysiologists, and brain theorists in various departments of Tlibingen University have gathered periodically in an effort to review ideas and evidence on cerebel lar functions. At times, general solutions seemed close, when credit was given to various theoretical proposals advanced since the early days of cer ebellar physiology, however, it became clear in every case that a large part of the available facts refused to submit to the general ideas. As believers in the power of scientific discussion, we felt that the time was ripe for posing the problem of the cerebellum once more to a well articulated group of specialists that would include proponents of every disparate point of view. The sponsorship of the Max Planck Society and of the Deutsche Forschungsgemeinschaft, to whom we express our profound gratitude, made it possible to organize an international meeting in Septem ber, 1983. The aim of making new, even extravagant ideas palatable to each other was well accomplished by the participants. We trust that some of the ensuing excitement has been carried over into the printed version.
Book Synopsis The Rat Nervous System by : George Paxinos
Download or read book The Rat Nervous System written by George Paxinos and published by Academic Press. This book was released on 2014-07-01 with total page 1053 pages. Available in PDF, EPUB and Kindle. Book excerpt: The previous editions of The Rat Nervous System were indispensable guides for those working on the rat and mouse as experimental models. The fourth edition enhances this tradition, providing the latest information in the very active field of research on the brain, spinal cord, and peripheral nervous system. The structure, connections, and function are explained in exquisite detail, making this an essential book for any graduate student or scientist working on the rat or mouse nervous system. Completely revised and updated content throughout, with entirely new chapters added Beautifully illustrated so that even difficult concepts are rendered comprehensible Provides a fundamental analysis of the anatomy of all areas of the central and peripheral nervous systems, as well as an introduction to their functions Appeals to researchers working on other species, including humans
Book Synopsis Integrated Systems of the CNS, Part III by : A. Bjorklund
Download or read book Integrated Systems of the CNS, Part III written by A. Bjorklund and published by Elsevier. This book was released on 1996-08-23 with total page 583 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book represents the third part of Integrated Systems of the CNS in the Handbook of Chemical Neuroanatomy. Part I is concerned with limbic regions and the hypothalamus, as well as with the retina. Part II contains reviews of central pathways associated with four major sensory systems. Part III is dedicated to W.J.H. Nauta, best remembered for the first selective silver implantation technique for dealing with degenerating axons. The volume is divided into three sections: the cerebellum, chemoarchitecture and anatomy; the basal ganglia; and the olfactory system. An excellent volume to keep pace with this challenging and rapidly developing field.
Book Synopsis Cerebellum and Neuronal Plasticity by : M. Glickstein
Download or read book Cerebellum and Neuronal Plasticity written by M. Glickstein and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Subcortical Structures and Cognition by : Leonard F. Koziol
Download or read book Subcortical Structures and Cognition written by Leonard F. Koziol and published by Springer Science & Business Media. This book was released on 2009-04-21 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical psychologists and neuropsychologists are traditionally taught that cognition is mediated by the cortex and that subcortical brain regions mediate the coordination of movement. However, this argument can easily be challenged based upon the anatomic organization of the brain. The relationship between the prefrontal cortex/frontal lobes and basal ganglia is characterized by loops from these anterior brain regions to the striatum, the globus pallidus, and the thalamus, and then back to the frontal cortex. There is also a cerebrocerebellar system defined by projections from the cerebral cortex to the pontine nuclei, to the cerebellar cortex and deep cerebellar nuclei, to the red nucleus and then back to thalamus and cerebral cortex, including all regions of the frontal lobes. Therefore, both the cortical-striatal and cortical-cerebellar projections are anatomically defined as re-entrant systems that are obviously in a position to influence not only motor behavior, but also cognition and affect. This represents overwhelming evidence based upon neuroanatomy alone that subcortical regions play a role in cognition. The first half of this book defines the functional neuroanatomy of cortical-subcortical circuitries and establishes that since structure is related to function, what the basal ganglia and cerebellum do for movement they also do for cognition and emotion. The second half of the book examines neuropsychological assessment. Patients with lesions restricted to the cerebellum and/or basal ganglia have been described as exhibiting a variety of cognitive deficits on neuropsychological tests. Numerous investigations have demonstrated that higher-level cognitive functions such as attention, executive functioning, language, visuospatial processing, and learning and memory are affected by subcortical pathologies. There is also considerable evidence that the basal ganglia and cerebellum play a critical role in the regulation of affect and emotion. These brain regions are an integral part of the brain’s executive system. The ability to apply new methodologies clinically is essential in the evaluation of disorders with subcortical pathology, including various developmental disorders (broadly defined to include learning disorders and certain psychiatric conditions), for the purpose of gaining greater understanding of these conditions and developing appropriate methodologies for treatment. The book is organized around three sources of evidence: neuroanatomical connections; patients with various disease processes; experimental studies, including various imaging techniques. These three sources of data present compelling evidence that the basal ganglia and cerebellum are involved in cognition, affect, and emotion. The question is no longer if these subcortical regions are involved in these processes, but instead, how they are involved. The book is also organized around two basic concepts: (1) the functional neuroanatomy of the basal ganglia and the cerebellum; and (2) how this relates to behavior and neuropsychological testing. Cognitive neuroscience is entering a new era as we recognize the roles of subcortical structures in the modulation of cognition. The fields of neuropsychology, cognitive psychology, neuropsychiatry, and neurology are all developing in the direction of understanding the roles of subcortical structures in behavior. This book is informative while defining the need and direction for new paradigms and methodologies for neuropsychological assessment.
Author :United States. Congress. House. Committee on Veterans' Affairs. Subcommittee on Hospitals and Health Care Publisher : ISBN 13 : Total Pages :248 pages Book Rating :4.3/5 (121 download)
Book Synopsis Veterans' Administration's Research Program on Prosthetics and Rehabilitation by : United States. Congress. House. Committee on Veterans' Affairs. Subcommittee on Hospitals and Health Care
Download or read book Veterans' Administration's Research Program on Prosthetics and Rehabilitation written by United States. Congress. House. Committee on Veterans' Affairs. Subcommittee on Hospitals and Health Care and published by . This book was released on 1984 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Cerebellum written by and published by Elsevier. This book was released on 1967-01-01 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Cerebellum
