The Molecular Repertoire of Adenoviruses III

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Publisher : Springer Science & Business Media
ISBN 13 : 3642795862
Total Pages : 322 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis The Molecular Repertoire of Adenoviruses III by : Walter Doerfler

Download or read book The Molecular Repertoire of Adenoviruses III written by Walter Doerfler and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: For decades this virus system has served--and continues to do so--to pioneer investigations on the molecular biology, biochemistry and genetics of mammalian cell systems. This three volume work presents an up-to-date account of recent basic research in one of the most important experimental systems for biochemical, cell biological, genetic, virological and epidemiological investigation in mammalian molecular biology. In the first of the three volumes, we present an overview of adenovirus research. In the second volume, we turn our attention to such topics as DNA replication, recombination and integration and post-trans- criptional control. This, the third volume then looks at transformation and E1A, adenovirus genetics, pathogenesis and gene therapy.

The Molecular Repertoire of Adenoviruses I

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Publisher : Springer Science & Business Media
ISBN 13 : 3642794963
Total Pages : 292 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis The Molecular Repertoire of Adenoviruses I by : Walter Doerfler

Download or read book The Molecular Repertoire of Adenoviruses I written by Walter Doerfler and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: For decades this virus system has served - and continues to do so - to pioneer investigations on the molecular biology, biochemistry and genetics of mammalian cell systems. This three volume work presents an up-to-date account of recent basic research in one of the most important experimental systems for biochemical, cell biological, genetic, virological, and epidemiological investigations in mammalian molecular biology. In this, the first of the three volumes, an overview of adenovirus research is presented with emphasis on the structure and assembly of adenoviruses, viral infections, and viral gene products. The chapters have been written by an international group of leading experts in their respective fields of interest.

The Molecular Repertoire of Adenoviruses II

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Publisher : Springer Science & Business Media
ISBN 13 : 3642794998
Total Pages : 291 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis The Molecular Repertoire of Adenoviruses II by : Walter Doerfler

Download or read book The Molecular Repertoire of Adenoviruses II written by Walter Doerfler and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: For decades this virus system has served--and continues to do so--to pioneer investigations on the molecular biology, biochemistry and genetics of mammalian cell systems. This three volume work presents an up-to-date account of recent basic research in one of the most important experimental systems for biochemical, cell biological, genetic, virological and epidemiological investigations in mammalian molecular biology. In this, the second of three volumes, the attention is turned to such topics as DNA replication, recombination and integration, and post-transcriptional control. The chapters have been written by an international group of leading experts in their respective fields of interest.

The Molecular Repertoire of Adenoviruses

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (332 download)

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Book Synopsis The Molecular Repertoire of Adenoviruses by : Walter Doerfler

Download or read book The Molecular Repertoire of Adenoviruses written by Walter Doerfler and published by . This book was released on 1995 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Molecular Repertoire of Adenoviruses I

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Author :
Publisher : Springer
ISBN 13 : 9783540588283
Total Pages : 0 pages
Book Rating : 4.5/5 (882 download)

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Book Synopsis The Molecular Repertoire of Adenoviruses I by : Walter Doerfler

Download or read book The Molecular Repertoire of Adenoviruses I written by Walter Doerfler and published by Springer. This book was released on 1995-08-16 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: For decades this virus system has served - and continues to do so - to pioneer investigations on the molecular biology, biochemistry and genetics of mammalian cell systems. This three volume work presents an up-to-date account of recent basic research in one of the most important experimental systems for biochemical, cell biological, genetic, virological, and epidemiological investigations in mammalian molecular biology. In this, the first of the three volumes, an overview of adenovirus research is presented with emphasis on the structure and assembly of adenoviruses, viral infections, and viral gene products. The chapters have been written by an international group of leading experts in their respective fields of interest.

The Molecular Repertoire of Adenoviruses II

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Publisher : Springer
ISBN 13 : 9783540588290
Total Pages : 0 pages
Book Rating : 4.5/5 (882 download)

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Book Synopsis The Molecular Repertoire of Adenoviruses II by : Walter Doerfler

Download or read book The Molecular Repertoire of Adenoviruses II written by Walter Doerfler and published by Springer. This book was released on 1995-08-16 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: For decades this virus system has served--and continues to do so--to pioneer investigations on the molecular biology, biochemistry and genetics of mammalian cell systems. This three volume work presents an up-to-date account of recent basic research in one of the most important experimental systems for biochemical, cell biological, genetic, virological and epidemiological investigations in mammalian molecular biology. In this, the second of three volumes, the attention is turned to such topics as DNA replication, recombination and integration, and post-transcriptional control. The chapters have been written by an international group of leading experts in their respective fields of interest.

Molecular Biology of Adenoviruses

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Publisher : Springer Science & Business Media
ISBN 13 : 370918391X
Total Pages : 118 pages
Book Rating : 4.7/5 (91 download)

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Book Synopsis Molecular Biology of Adenoviruses by : L. Philipson

Download or read book Molecular Biology of Adenoviruses written by L. Philipson and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 118 pages. Available in PDF, EPUB and Kindle. Book excerpt: I. Introduction In his biography "Arrow in the Blue" the author Arthur Koestler suggests ironically that the fate of an individual may be predicted by examining the content of the newspapers at birth. Adenoviruses were discovered in 1953 (ROWE et al. , 1953; HILLEMAN and WERNER, 1954). At this time the Salk poliomyelitis vaccine was developed (SALK et al. , 1954) and in the same year the discovery of the double helical structure of DNA (WATSON and CRICK, 1953) and the plaque assay for one animal virus (DULBECCO and VOGT, 1953) was announced. Thus, this new group of viruses was born with great hopes for progress in molecular biology and for the control of animal virus infections. In the short interval be tween 1953 and 1956 the adenoviruses were discovered, methods for laboratory diagnosis and serotyping were established, the epidemiology was clarified and a highly effective vaccine was developed and approved (for a review see HILLE MAN, 1966). Succeeding years showed, however, that the vaccines were contami nated with the oncogenic SV 40 virus and that the adenoviruses themselves were tumorigenic. Since the discovery of adenoviruses animal virology was developed into a quantitative science offering explanation for viral functions at the molecular level. Precise biochemical tools to characterize the genome and its transcription products as well as the structural proteins of these viruses are now available.

Adenoviruses: Model and Vectors in Virus-Host Interactions

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Publisher : Springer Science & Business Media
ISBN 13 : 366205597X
Total Pages : 453 pages
Book Rating : 4.6/5 (62 download)

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Book Synopsis Adenoviruses: Model and Vectors in Virus-Host Interactions by : Walter Doerfler

Download or read book Adenoviruses: Model and Vectors in Virus-Host Interactions written by Walter Doerfler and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: After three volumes on adenoviruses in 1995 the past years have seen rapid progress in the field of adenovirus research. Moreover, adenoviruses have attracted considerable interest as vectors in gene transfer regimens.

Adenoviral Vectors for Gene Therapy

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Publisher : Academic Press
ISBN 13 : 0128005106
Total Pages : 868 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Adenoviral Vectors for Gene Therapy by : David T. Curiel

Download or read book Adenoviral Vectors for Gene Therapy written by David T. Curiel and published by Academic Press. This book was released on 2016-03-10 with total page 868 pages. Available in PDF, EPUB and Kindle. Book excerpt: Adenoviral Vectors for Gene Therapy, Second Edition provides detailed, comprehensive coverage of the gene delivery vehicles that are based on the adenovirus that is emerging as an important tool in gene therapy. These exciting new therapeutic agents have great potential for the treatment of disease, making gene therapy a fast-growing field for research. This book presents topics ranging from the basic biology of adenoviruses, through the construction and purification of adenoviral vectors, cutting-edge vectorology, and the use of adenoviral vectors in preclinical animal models, with final consideration of the regulatory issues surrounding human clinical gene therapy trials. This broad scope of information provides a solid overview of the field, allowing the reader to gain a complete understanding of the development and use of adenoviral vectors. Provides complete coverage of the basic biology of adenoviruses, as well as their construction, propagation, and purification of adenoviral vectors Introduces common strategies for the development of adenoviral vectors, along with cutting-edge methods for their improvement Demonstrates noninvasive imaging of adenovirus-mediated gene transfer Discusses utility of adenoviral vectors in animal disease models Considers Federal Drug Administration regulations for human clinical trials

Gene Therapy

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Publisher : Academic Press
ISBN 13 : 9780080581323
Total Pages : 508 pages
Book Rating : 4.5/5 (813 download)

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Book Synopsis Gene Therapy by :

Download or read book Gene Therapy written by and published by Academic Press. This book was released on 1997-08-12 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt: Each volume of Advances in Pharmacology provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular bases of drug action, both applied and experimental. Volume 40, GeneTherapy, features important new research on gene transfers and therapy in the herpes simplex virus, anti-tumor immunity, steroid receptors, cystic fibroses, and more. Key Features * It provides an excellent overview on a series of topics on gene therapy for the serious investigator

Encyclopedia of Toxicology

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Publisher : Academic Press
ISBN 13 : 0127453547
Total Pages : 3734 pages
Book Rating : 4.1/5 (274 download)

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Book Synopsis Encyclopedia of Toxicology by : Philip Wexler

Download or read book Encyclopedia of Toxicology written by Philip Wexler and published by Academic Press. This book was released on 2005 with total page 3734 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Encyclopedia of Toxicology second edition continues its comprehensive survey of toxicology. This new edition presents entries devoted to specific chemicals, the international scope of organizations included has been broadened, and articles describing a number of well-known toxic-related incidents such as Chernobyl and Three-Mile Island are included. Along with the traditional scientifically-based entries, new articles focus on the societal implications of toxicological knowledge including environmental crimes, chemical and biological warfare in ancient times, and a history of the U.S. environmental movement. With more than 1150 entries, this second edition has been expanded in length, breadth and depth and provides an extensive overview of the many facets of toxicology. (Midwest).

Encyclopedia of Virology

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Publisher : Elsevier
ISBN 13 : 0080547974
Total Pages : 4500 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Encyclopedia of Virology by : Allan Granoff

Download or read book Encyclopedia of Virology written by Allan Granoff and published by Elsevier. This book was released on 1999-07-27 with total page 4500 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, progress in the field of virology has advanced at an unprecedented rate. Issues such as AIDS have brought the subject firmly into the public domain and its study is no longer confined solely to specialist groups. The Encyclopedia of Virology is the largest single reference source of current virological knowledge. It is also the first to bring together all aspects of the subject for a wide variety of readers. Unique in its use of concise 'mini-review' articles, the material covers biological, molecular, and medical topics concerning viruses in animals, plants, bacteria, and insects. More general articles focus on the effects of viruses on the immune system, the role of viruses in disease, oncology, gene therapy, and evolution, plus a wide range of related topics. Drawing on the latest research, the editors have produced the definitive source for both specialist and general readers. Easy-to-use and meticulously organized, the Encyclopedia of Virology clarifies and illuminates one of the most complex areas of contemporary study. It will prove an invaluable addition to libraries, universities, medical and nursing schools, and research institutions around the world. The Second Edition has been thoroughly updated with approximately 40 new articles. This edition includes more illustrations and color plates in each volume. Updated thoroughly with approximately 40 new articles Presents more illustrations than the first edition, with color plates in each volume Contains a complete subject index in each volume Provides further reading lists at the end of each entry, allowing easy access to the primary literature Extensive cross-referencing system links all related articles Contains the most recent information of particular viruses described at the 7th International Committee on Taxonomy and Classification of Viruses Provides the ability to search for entries alphabetically or via the taxonomical listings to access articles of different viruses

Gene Therapy Protocols

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Publisher : Springer Science & Business Media
ISBN 13 : 1592591418
Total Pages : 521 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Gene Therapy Protocols by : Jeffrey R. Morgan

Download or read book Gene Therapy Protocols written by Jeffrey R. Morgan and published by Springer Science & Business Media. This book was released on 2007-10-26 with total page 521 pages. Available in PDF, EPUB and Kindle. Book excerpt: Efforts in gene therapy have grown dramatically in recent years. Basic research as well as clinical activity have made exciting progress and are beg- ning to offer renewed hope that gene therapy may be able to deliver novel approaches for the treatment of inherited as well as such acquired diseases as cardiovascular disease and cancer. With the sequencing of the human genome complete, we now have a comprehensive catalog of genes that further expands the potential role of gene therapy into such new fields as tissue engineering. Central to gene therapy is the process of gene transfer; thus, advances in the technology of gene transfer are at the heart of this field’s progress. Numerous technologies, based on a variety of methods (e.g., viral-mediated, physical/ chemical), have been developed to achieve gene transfer. Some of the earliest methods, such as recombinant retroviruses, are still widely used, have undergone significant improvements, and have given rise to new vectors based on lentiviruses.

Functional Analysis of the Human Genome

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Publisher : Garland Science
ISBN 13 : 1000140962
Total Pages : 314 pages
Book Rating : 4.0/5 (1 download)

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Book Synopsis Functional Analysis of the Human Genome by : F. Farzaneh

Download or read book Functional Analysis of the Human Genome written by F. Farzaneh and published by Garland Science. This book was released on 2020-09-10 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: An excellent review of the relationship between structure and function in the human genome, and a detailed description of some of the important methodologies for unravelling the function of genes and genomic structures.

Clinical Virology

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Publisher : American Society for Microbiology Press
ISBN 13 : 1555814255
Total Pages : 4206 pages
Book Rating : 4.5/5 (558 download)

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Book Synopsis Clinical Virology by : Douglas D. Richman

Download or read book Clinical Virology written by Douglas D. Richman and published by American Society for Microbiology Press. This book was released on 2009-01-01 with total page 4206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Informs scientists and health care professionals about all the medically relevant aspects of this rapidly evolving field. • Covers novel viruses, pathogenesis, epidemiology, diagnosis, treatment, and prevention. • Addresses infections and syndromes related to particular organ systems, as well as the fundamentals of modern medical virology. • Includes crucial information on immune responses and vaccinology, diagnostics, antivirals, and the nascent field of gene therapy. • Provides agent-specific chapters that detail the virology, epidemiology, pathogenesis, clinical manifestations, and prevention and treatment of important viral pathogens.

Encyclopedia of Cancer

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Publisher : Springer Science & Business Media
ISBN 13 : 3540368477
Total Pages : 3307 pages
Book Rating : 4.5/5 (43 download)

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Book Synopsis Encyclopedia of Cancer by : Manfred Schwab

Download or read book Encyclopedia of Cancer written by Manfred Schwab and published by Springer Science & Business Media. This book was released on 2008-09-23 with total page 3307 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive encyclopedic reference provides rapid access to focused information on topics of cancer research for clinicians, research scientists and advanced students. Given the overwhelming success of the first edition, which appeared in 2001, and fast development in the different fields of cancer research, it has been decided to publish a second fully revised and expanded edition. With an A-Z format of over 7,000 entries, more than 1,000 contributing authors provide a complete reference to cancer. The merging of different basic and clinical scientific disciplines towards the common goal of fighting cancer makes such a comprehensive reference source all the more timely.

Foreign DNA in Mammalian Systems

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Publisher : John Wiley & Sons
ISBN 13 : 3527613471
Total Pages : 194 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Foreign DNA in Mammalian Systems by : Walter Doerfler

Download or read book Foreign DNA in Mammalian Systems written by Walter Doerfler and published by John Wiley & Sons. This book was released on 2008-07-11 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is unlikely that the established genomes of present day organisms remain stable forever. It is conceivable that foreign DNA can gain entry into individual cells of an organism. Foreign DNA is defined as genetic material that derives from another organism of the same or a different species. The natural environment is heavily "contaminated" with such foreign DNA, and mammals, like other organisms, are frequently exposed to foreign DNA in their environment, notably by ingesting their daily food supply. By necessity, the gastrointestinal tract also of all mammalian organisms is constantly in contact with foreign DNA. So far, next to nothing is known about defense mechanisms in mammals against the intrusion of foreign DNA. At least in cells growing in culture, the uptake and genomic fixation by integration of foreign DNA can readily be demonstrated. For a number of reasons, the author has considered it important to investigate the phenomena and mechanisms involved in the interaction of foreign DNA with mammalian cells and organisms in detail.