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The Mass Spectrometer
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Book Synopsis Mass Spectrometry by : Jürgen H Gross
Download or read book Mass Spectrometry written by Jürgen H Gross and published by Springer Science & Business Media. This book was released on 2006-04-05 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mass Spectrometry is an ideal textbook for students and professionals as well as newcomers to the field. Starting from the very first principles of gas-phase ion chemistry and isotopic properties, the textbook takes the reader through the design of mass analyzers and ionization methods all the way to mass spectral interpretation and coupling techniques. Step-by-step, the reader learns how mass spectrometry works and what it can do. The book comprises a balanced mixture of practice-oriented information and theoretical background. It features a clear layout and a wealth of high-quality figures. Exercises and solutions are located on the Springer Global Web.
Book Synopsis Mass Spectrometry by : Edmond de Hoffmann
Download or read book Mass Spectrometry written by Edmond de Hoffmann and published by Wiley. This book was released on 2001-10-10 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offers a complete overview of the principles, theories and key applications of modern mass spectrometry in this introductory textbook. Following on from the highly successful first edition, this edition is extensively updated including new techniques and applications. All instrumental aspects of mass spectrometry are clearly and concisely described; sources, analysers and detectors. * Revised and updated * Numerous examples and illustrations are combined with a series of exercises to help encourage student understanding * Includes biological applications, which have been significantly expanded and updated * Also includes coverage of ESI and MALDI
Download or read book Neuroproteomics written by Oscar Alzate and published by CRC Press. This book was released on 2009-10-26 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this, the post-genomic age, our knowledge of biological systems continues to expand and progress. As the research becomes more focused, so too does the data. Genomic research progresses to proteomics and brings us to a deeper understanding of the behavior and function of protein clusters. And now proteomics gives way to neuroproteomics as we begin to unravel the complex mysteries of neurological diseases that less than a generation ago seemed opaque to our inquiries, if not altogether intractable. Edited by Dr. Oscar Alzate, Neuroproteomics is the newest volume in the CRC Press Frontiers of Neuroscience Series. With an extensive background in mathematics and physics, Dr. Alzate exemplifies the newest generation of biological systems researchers. He organizes research and data contributed from all across the world to present an overview of neuroproteomics that is practical and progressive. Bolstered by each new discovery, researchers employing multiple methods of inquiry gain a deeper understanding of the key biological problems related to brain function, brain structure, and the complexity of the nervous system. This in turn is leading to new understanding about diseases of neurological deficit such as Parkinson’s and Alzheimer’s. Approaches discussed in the book include mass spectrometry, electrophoresis, chromatography, surface plasmon resonance, protein arrays, immunoblotting, computational proteomics, and molecular imaging. Writing about their own work, leading researchers detail the principles, approaches, and difficulties of the various techniques, demonstrating the questions that neuroproteomics can answer and those it raises. New challenges wait, not the least of which is the identification of potential methods to regulate the structures and functions of key protein interaction networks. Ultimately, those building on the foundation presented here will advance our understanding of the brain and show us ways to abate the suffering caused by neurological and mental diseases.
Book Synopsis Principles and Applications of Clinical Mass Spectrometry by : Nader Rifai
Download or read book Principles and Applications of Clinical Mass Spectrometry written by Nader Rifai and published by Elsevier. This book was released on 2018-06-26 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles and Applications of Clinical Mass Spectrometry: Small Molecules, Peptides, and Pathogens is a concise resource for quick implementation of mass spectrometry methods in clinical laboratory work. Focusing on the practical use of these techniques, the first half of the book covers principles of chromatographic separations, principles and types of mass spectrometers, and sample preparation for analysis; the second half outlines the main applications of this technology within clinical laboratory settings, including determination of small molecules and peptides, as well as pathogen identification. A thorough yet succinct guide to using mass spectrometry technology in the clinical laboratory, Principles and Applications of Clinical Mass Spectrometry: Small Molecules, Peptides, and Pathogens is an essential resource for chemists, pharmaceutical and biotech researchers, certain government agencies, and standardization groups. Provides concrete examples of the main applications of mass spectrometry technology Describes current capabilities of the LC- and MS-based analytical methods Details methods for successful analytical work in the field
Book Synopsis Quadrupole Mass Spectrometry and Its Applications by : Peter H. Dawson
Download or read book Quadrupole Mass Spectrometry and Its Applications written by Peter H. Dawson and published by Elsevier. This book was released on 2013-10-22 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: Quadrupole Mass Spectrometry and Its Applications provides a comprehensive discussion of quadrupoles and their applications. It proceeds from a general explanation of the action of radiofrequency quadrupole fields to the description of their utilization in mass analyzers—such as the quadrupole mass filter, the monopole, the three-dimensional quadrupole ion trap, and various time-of-flight spectrometers—and finally to the characteristic applications of quadrupoles. A multi-author format has been adopted to provide broader-than-usual viewpoint in the book. The book begins by explaining the principles of operation of quadrupole devices. These include ion trajectories and computer simulations of performance; analytical theory; numerical methods of calculation of performance, including the recently developed application of phase-space dynamics; and fringing fields and other field imperfections. Subsequent chapters provide design and performance evaluations of the mass filter, the monopole, ion traps, and time-of-flight instruments; and describe areas of application where quadrupole devices have made the greatest impact because of their particular advantages and disadvantages.
Book Synopsis Accelerator Mass Spectrometry by : Claudio Tuniz
Download or read book Accelerator Mass Spectrometry written by Claudio Tuniz and published by CRC Press. This book was released on 1998-03-25 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: This extensive undertaking, Accelerator Mass Spectrometry, conducts an elaborate and comprehensive summary of one of the foremost catalysts of progress in scientific research. Accelerator mass spectrometry (AMS), an innovative analytical technique, measures rare atoms at unprecedented levels of sensitivity, revolutionizing the science of radiocarbon dating and accessing new natural radioisotopes as environmental tracers and chronometers. This book demonstrates how AMS is applied in the studies of extraterrestrial materials, the earth sciences, the future of the global environment, and the history of mankind. This compendium also highlights the significant impact of AMS on several fields of scientific investigation, spurring remarkable studies in global climate change, ancient artifacts, pollution, nuclear safeguards, geochronology, and materials characterization. The myriad of sample types and variety of applications in this examination include: Meteorites from Mars Ancient air trapped in Antarctic ice The Shroud of Turin The dating of human bones The colonization of the Americas and Australia Ancient rock art The crown of Charlemagne Cancerogenic effects of cooked meat The consequences of the Chernobyl accident The role of aluminum in Alzheimer's Disease This unique edition has compiled the diverse set of scientific literature into a single volume, suitable as a text or resource on the major AMS-related outcomes, issues, and methods.
Book Synopsis Fundamentals of Mass Spectrometry by : Kenzo Hiraoka
Download or read book Fundamentals of Mass Spectrometry written by Kenzo Hiraoka and published by Springer Science & Business Media. This book was released on 2013-06-13 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most research and all publications in mass spectrometry address either applications or practical questions of procedure. This book, in contrast, discusses the fundamentals of mass spectrometry. Since these basics (physics, chemistry, kinetics, and thermodynamics) were worked out in the 20th century, they are rarely addressed nowadays and young scientists have no opportunity to learn them. This book reviews a number of useful methods in mass spectrometry and explains not only the details of the methods but the theoretical underpinning.
Book Synopsis Introduction to Mass Spectrometry by : J. Throck Watson
Download or read book Introduction to Mass Spectrometry written by J. Throck Watson and published by John Wiley & Sons. This book was released on 2013-07-09 with total page 864 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely revised and updated, this text provides an easy-to-read guide to the concept of mass spectrometry and demonstrates its potential and limitations. Written by internationally recognised experts and utilising "real life" examples of analyses and applications, the book presents real cases of qualitative and quantitative applications of mass spectrometry. Unlike other mass spectrometry texts, this comprehensive reference provides systematic descriptions of the various types of mass analysers and ionisation, along with corresponding strategies for interpretation of data. The book concludes with a comprehensive 3000 references. This multi-disciplined text covers the fundamentals as well as recent advance in this topic, providing need-to-know information for researchers in many disciplines including pharmaceutical, environmental and biomedical analysis who are utilizing mass spectrometry
Book Synopsis Rays of Positive Electricity and Their Application to Chemical Analyses by : Joseph John Thomson
Download or read book Rays of Positive Electricity and Their Application to Chemical Analyses written by Joseph John Thomson and published by . This book was released on 1913 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Introductory Mass Spectrometry, Second Edition by : Stephen Shrader
Download or read book Introductory Mass Spectrometry, Second Edition written by Stephen Shrader and published by CRC Press. This book was released on 2013-11-12 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mass spectrometry has played an integral part in the study of organic molecular structures for more than 50 years, offering significant information from small amounts of sample. The mass spectrum produced by electron impact ionization presents a pattern of peaks that can often give definitive structural information about an unknown compound. Introductory Mass Spectrometry, Second Edition guides readers in the understanding and recognition of those patterns, discussing mass spectra in terms that are familiar to chemists. It provides a basis for chemists to interpret mass spectra to solve particular structural problems. The Second Edition has been updated with modern techniques and data handling. Beginning with an introduction to the principles and instrumentation, it then sequentially explains the processes that occur in the mass spectrometer following ionization. The book is unique in the large number of mass spectra presented and provides examples of mass spectra from a wide variety of organic chemicals, concentrating on the relationships between fragmentation patterns, common chemical reactions, and chemical structures. The book also discusses mass spectra obtained with softer ionization techniques, which provide definitive information regarding molecular weights. The text describes mass spectra produced by electron ionization, discussing how the spectral peak pattern relates to molecular structure. It details the use of high-resolution and accurate mass measurement to determine elemental composition of ions in order to identify unknown substances. The book also introduces some of the recent techniques that can be employed to extend the usefulness of mass spectrometry to high molecular weight substances and more polar substances. It includes examples and problems representing a cross section of organic chemistry to help readers integrate the principles presented.
Book Synopsis Time-of-Flight Mass Spectrometry and its Applications by : E.W. Schlag
Download or read book Time-of-Flight Mass Spectrometry and its Applications written by E.W. Schlag and published by Newnes. This book was released on 2012-12-02 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: The resurgence of time-of-flight mass spectrometry (TOF-MS) has had its origin in the simplicity of construction and application of such instruments together with the high transmission and the great increase in resolution that has been achieved. The instrument lends itself naturally to a coupling with pulsed laser sources, though this is not a prerequisite. It also affords a time resolution far beyond that traditionally achieved with mass spectrometric rapid scan techniques - a recent example being the real-time analysis of a multi-component mixture from an automobile exhaust. Furthermore, the mass range appears to be extremely large: mass up to 500 kDa and beyond what is being readily measured in the laboratory today. The present set of contributions attempts to give a survey of current applications from many of the active groups in the field. A variety of new applications are considered which are no doubt just the beginning of large new areas of application. By presenting this work in book form it is hoped that it will be of help to the many groups intending to initiate work in this rapidly expanding new area of mass spectrometry.
Book Synopsis Mass Spectrometry for the Novice by : John Greaves
Download or read book Mass Spectrometry for the Novice written by John Greaves and published by CRC Press. This book was released on 2013-10-16 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: With usage of mass spectrometry continually expanding, an increasing number of scientists, technicians, students, and physicians are coming into contact with this valuable technique. Mass spectrometry has many uses, both qualitative and quantitative, from analyzing simple gases to environmental contaminants, pharmaceuticals, and complex biopolymers
Book Synopsis Mass Spectrometry in Medicinal Chemistry by : Klaus Wanner
Download or read book Mass Spectrometry in Medicinal Chemistry written by Klaus Wanner and published by John Wiley & Sons. This book was released on 2007-06-27 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: This first overview of mass spectrometry-based pharmaceutical analysis is the key to improved high-throughput drug screening, rational drug design and analysis of multiple ligand-target interactions. The ready reference opens with a general introduction to the use of mass spectrometry in pharmaceutical screening, followed by a detailed description of recently developed analytical systems for use in the pharmaceutical laboratory. Applications range from simple binding assays to complex screens of biological activity and systems containing multiple targets or ligands -- all highly relevant techniques in the early stages in drug discovery, from target characterization to hit and lead finding.
Book Synopsis Advances in Mass Spectrometry by : R. M. Elliott
Download or read book Advances in Mass Spectrometry written by R. M. Elliott and published by Elsevier. This book was released on 2013-10-22 with total page 646 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Mass Spectrometry, Volume 2 documents the proceedings of a conference on mass spectrometry held in Oxford in September 1961. This compilation is categorized into six major topics — mass spectrometry in research; mass spectrometry of inorganic compounds; instruments and techniques; theory and correlation of mass spectra; mass spectra and analysis; and ionization and dissociation. Under these major topics, parts of the papers discussed include field ionization mass spectroscopy; initial kinetic energy discrimination effects in crossed-field ion sources; mass spectrometric study of CaO and Ta; and spark source mass spectrometry as an analytical technique. The book also covers discussions on initial energy of hydrocarbon fragment ions; determination of the structure of alkaloids by mass spectrometry; and application of a time-of-flight mass spectrometer to the examination of ion-molecule interactions. This volume is a useful reference to students and researchers conducting work on mass spectrometry.
Book Synopsis The Expanding Role of Mass Spectrometry in Biotechnology by : Gary Siuzdak
Download or read book The Expanding Role of Mass Spectrometry in Biotechnology written by Gary Siuzdak and published by . This book was released on 2006 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covers the basic concepts in mass spectrometry as well as advanced topics including protein identification/protein structural analysis, carbohydrate and oligonucleotide analysis. Topics also include pharmacokinetics, high throughput screening, and the recent development of mass spectrometry in clinical diagnosis.
Book Synopsis The Mass Spectrometer by : Frances L. Sachs
Download or read book The Mass Spectrometer written by Frances L. Sachs and published by . This book was released on 1953 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Mass Spectrometry for Chemists and Biochemists by : Robert A. W. Johnstone
Download or read book Mass Spectrometry for Chemists and Biochemists written by Robert A. W. Johnstone and published by Cambridge University Press. This book was released on 1996-10-17 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the full range of mass spectrometry techniques and applications. This versatile technique is in ubiquitous use in universities and industry laboratories because of its ability to identify and quantify materials quickly and, if necessary, in minute amounts, and solve analytical problems in a huge variety of fields. The authors adopt an instructional approach and make use of recent examples to illustrate important points. This second edition includes new methods and applications that have developed in the last ten years. Powerful methods combining mass spectrometry with newer separation techniques, the increased use of computers, and analysis of once difficult polar and large-mass compounds such as proteins using new ionisation methods are all discussed. Requiring no previous knowledge of mass spectrometry, this is an ideal teaching text at both undergraduate and postgraduate level, and will also be of considerable interest to research workers.
