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The Mab
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Download or read book The Mab written by Matt Brown and published by Unbound Publishing. This book was released on 2022-06-09 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: ‘These stories make the wall between worlds thrillingly thin. Their enchantment calls to us ever from the other side of the door’ Michael Sheen, from the foreword If you think you’ve heard all the fairy tales out there, think again. Inside this book you will find eleven epic Welsh tales from long ago, but not so far away, that are bound to enchant you. The Mab is a collection full to the brim with brand new versions of really, really old stories from the Mabinogi – maybe the oldest written-down stories in the history of Britain. But as well as being really, really old, the stories in The Mab are strange and funny and thrilling. Alive with mystery and magic, they speak of a time when the gates between the Real World and the Otherworld were occasionally left open. And sometimes, just sometimes, it was possible to step through. The stories in this illustrated edition have been reimagined by an extraordinary team of writers, and each appears alongside a Welsh-language translation.
Book Synopsis Memoir of a Race Traitor by : Mab Segrest
Download or read book Memoir of a Race Traitor written by Mab Segrest and published by South End Press. This book was released on 1994 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: 'Courageous and daring, this work documents the reality that political solidarity, forged in struggle, can exist across difference.' bell hooks
Book Synopsis Administrations of Lunacy by : Mab Segrest
Download or read book Administrations of Lunacy written by Mab Segrest and published by The New Press. This book was released on 2020-04-14 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Whew! They going to send around here and tie you up and drag you off to Milledgeville. Them fat blue police chasing tomcats around alleys." —Berenice in The Member of the Wedding by Carson McCullers A scathing and original look at the racist origins of the field of modern psychiatry, told through the story of what was once the largest mental institution in the world, by the prize-winning author of Memoir of a Race Traitor After a decade of research, Mab Segrest, whose Memoir of a Race Traitor forever changed the way we think about race in America, turns sanity itself inside-out in a stunning book that will become an instant classic. In December 1841, the Georgia State Lunatic, Idiot, and Epileptic Asylum was founded on land taken from the Cherokee nation in the then-State capitol of Milledgeville. A hundred years later, it had become the largest insane asylum in the world with over ten thousand patients. To this day, it is the site of the largest graveyard of disabled and mentally ill people in the world. In April, 1949, Ebony magazine reported that for black patients, "the situation approaches Nazi concentration camp standards . . . unbelievable this side of Dante's Inferno." Georgia's state hospital was at the center of psychiatric practice and the forefront of psychiatric thought throughout the nineteenth and twentieth centuries in America—centuries during which the South invented, fought to defend, and then worked to replace the most developed slave culture since the Roman Empire. A landmark history of a single insane asylum at Milledgeville, Georgia, A Peculiar Inheritance reveals how modern-day American psychiatry was forged in the traumas of slavery, the Civil War, and Reconstruction, when African Americans carrying "no histories" entered from Freedmen's Bureau Hospitals and home counties wracked with Klan terror. This history set the stage for the eugenics and degeneracy theories of the twentieth century, which in turn became the basis for much of Nazi thinking in Europe. Segrest's masterwork will forever change the way we think about our own minds.
Download or read book Born to Belonging written by Mab Segrest and published by Rutgers University Press. This book was released on 2002 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Veteran activist Mab Segrest takes readers along on her travels to view a world experiencing extraordinary change. As she moves from place to place, she speculates on the effects of globalization and urban development on individuals, examines the struggles for racial, economic, and sexual equality, and narrates her own history as a lesbian in the American South. From the principle that we all belong to the human community, Segrest uses her personal experience as a filter for larger political and cultural issues. Her writings bring together such groups as the Ku Klux Klan in North Carolina, fledging gay rights activists in Zimbabwe, and resistance fighters in El Salvador. Segrest expertly plumbs her own personal experiences for organizing principles and maxims to combat racism, homophobia, sexism, and economic exploitation.
Download or read book U.S. MAB Bulletin written by and published by . This book was released on 1993 with total page 8 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Queen Mab written by Kate Danley and published by Kate Danley. This book was released on 2013-05-11 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: WINNER - McDougall Previews Award for Best Fantasy Book of the Year From the mind of USA TODAY Bestselling author, Kate Danley, comes a new fairytale. When Faunus, the god of daydreams, breaks the heart of Queen Mab, revenge can be the only answer. Using the most powerful families in Verona, they wage their war against one another. But when Queen Mab falls in love with a man named Mercutio, she will do anything, even if it means destroying the world, to save him. Will it be enough to stop the tragedy? Or only spur it forward to its terrible end? Weaving Shakespeare's original text into a new fantasy, fans of The Woodcutter will delight in this loving retelling by award-winning author Kate Danley. Experience the romance and passion of Romeo & Juliet from a different point of view - through the eyes of the bringer of dreams... Queen Mab.
Book Synopsis Compton Valance - The Most Powerful Boy in the Universe by : Matt Brown
Download or read book Compton Valance - The Most Powerful Boy in the Universe written by Matt Brown and published by Usborne Publishing Ltd. This book was released on 2014-06-01 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt: How to become the most POWERFUL BOY IN THE UNIVERSE. 1. Leave cheese-and-pickled-egg SANDWICH in lunchbox for thirteen weeks. 2. Open lunchbox to find that sandwich has turned into a TIME MACHINE. 3. Accidentally wipe out the DINOSAURS with a packet of custard creams. 4. Try to stop someone evil stealing the most POWERFUL SANDWICH of all TIME and changing the history of the universe FOR EVER.
Book Synopsis My Body Can House Two Hearts by : Hanan Issa
Download or read book My Body Can House Two Hearts written by Hanan Issa and published by . This book was released on 2019-10 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: MY BODY CAN HOUSE TWO HEARTS skips across the fragile boundaries of history, culture, relationships, and language. It explores the transitory balance of belonging by tying threads between different places and ideas not often compared. Traverse the poet's perception of her Welsh and Iraqi heritage, her positioning as a woman of colour, and the nuances of feminist action. My Body Can House Two Hearts is a celebration of women's redemptive interdependency and the rejection of patriarchal power.
Book Synopsis A New roadmap for the Man and the Biosphere (MAB) Programme and its World Network of Biosphere Reserves by : UNESCO
Download or read book A New roadmap for the Man and the Biosphere (MAB) Programme and its World Network of Biosphere Reserves written by UNESCO and published by UNESCO Publishing. This book was released on 2017-03-20 with total page 53 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Queen Mab written by Percy Bysshe Shelley and published by . This book was released on 1820 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Biosimilars written by Hiten J. Gutka and published by Springer. This book was released on 2018-12-13 with total page 713 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of the biosimilar regulatory framework, the development process and clinical aspects for development of biosimilars. The development path of a biosimilar is just as unique as a development path of a new drug, tailored by the mechanism of action, the quality of the molecule, published information on the reference product, the current competitive environment, the target market and regulatory guidance, and most importantly, the emerging totality of evidence for the proposed biosimilar during development. For the ease of readers, the book comprises of six sections as follows: Section I: Business, Health Economics and Intellectual Property Landscape for Biosimilars Section II: Regulatory Aspects of Development and Approval for Biosimilars Section III: Biopharmaceutical Development and Manufacturing of Biosimilars Section IV: Analytical Similarity Considerations for Biosimilars Section V: Clinical aspects of Biosimilar Development Section VI: Biosimilars- Global Development and Clinical Experience Chapters have been written by one or more experts from academia, industry or regulatory agencies who have been involved with one or more aspects of biosimilar product development. The authors and editors have an expertise in commercialization and pricing of biosimilars, intellectual property considerations for biosimilars, chemistry manufacturing controls (CMC) and analytical development for biosimilars, regulatory and clinical aspects of biosimilar development. Besides the industry practitioners, the book includes several contributions from regulators across the globe.
Download or read book Avian Immunology written by Bernd Kaspers and published by Academic Press. This book was released on 2012-12-02 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of Avian Immunology provides an up-to-date overview of the current knowledge of avian immunology. From the ontogeny of the avian immune system to practical application in vaccinology, the book encompasses all aspects of innate and adaptive immunity in chickens. In addition, chapters are devoted to the immunology of other commercially important species such as turkeys and ducks, and to ecoimmunology summarizing the knowledge of immune responses in free-living birds often in relation to reproductive success. The book contains a detailed description of the avian innate immune system, encompassing the mucosal, enteric, respiratory and reproductive systems. The diseases and disorders it covers include immunodepressive diseases and immune evasion, autoimmune diseases, and tumors of the immune system. Practical aspects of vaccination are examined as well. Extensive appendices summarize resources for scientists including cell lines, inbred chicken lines, cytokines, chemokines, and monoclonal antibodies. The world-wide importance of poultry protein for the human diet, as well as the threat of avian influenza pandemics like H5N1 and heavy reliance on vaccination to protect commercial flocks makes this book a vital resource. This book provides crucial information not only for poultry health professionals and avian biologists, but also for comparative and veterinary immunologists, graduate students and veterinary students with an interest in avian immunology. - With contributions from 33 of the foremost international experts in the field, this book provides the most up-to-date review of avian immunology so far - Contains a detailed description of the avian innate immune system reviewing constitutive barriers, chemical and cellular responses; it includes a comprehensive review of avian Toll-like receptors - Contains a wide-ranging review of the "ecoimmunology" of free-living avian species, as applied to studies of population dynamics, and reviews methods and resources available for carrying out such research
Book Synopsis Biosphere Reserves and Sustainable Development Goals 2 by : Bruno Romagny
Download or read book Biosphere Reserves and Sustainable Development Goals 2 written by Bruno Romagny and published by John Wiley & Sons. This book was released on 2021-02-24 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since 1971, UNESCO's Man and the Biosphere (MAB) Programme has embraced a number of principles that link the political, scientific and academic spheres. Biosphere Reserves and Sustainable Development Goals 2 is a reminder of the fundamental issues involved in governance. The diversity and multiplicity of stakeholders, and the complexity of the interplay between them, as well as their organization, are decisive factors in the proper management of resources and territories. The book also presents a number of case studies demonstrating that, between the strong development aspirations of their populations, the impact of human activities and the need to conserve their biological heritage, the biosphere reserves of the southern Mediterranean are facing major issues: agricultural pollution, forest fires, water use in a context of climate change, etc.
Book Synopsis Monoclonal Antibody Production by : National Research Council
Download or read book Monoclonal Antibody Production written by National Research Council and published by National Academies Press. This book was released on 1999-05-06 with total page 74 pages. Available in PDF, EPUB and Kindle. Book excerpt: The American Anti-Vivisection Society (AAVS) petitioned the National Institutes of Health (NIH) on April 23, 1997, to prohibit the use of animals in the production of mAb. On September 18, 1997, NIH declined to prohibit the use of mice in mAb production, stating that "the ascites method of mAb production is scientifically appropriate for some research projects and cannot be replaced." On March 26, 1998, AAVS submitted a second petition, stating that "NIH failed to provide valid scientific reasons for not supporting a proposed ban." The office of the NIH director asked the National Research Council to conduct a study of methods of producing mAb. In response to that request, the Research Council appointed the Committee on Methods of Producing Monoclonal Antibodies, to act on behalf of the Institute for Laboratory Animal Research of the Commission on Life Sciences, to conduct the study. The 11 expert members of the committee had extensive experience in biomedical research, laboratory animal medicine, animal welfare, pain research, and patient advocacy (Appendix B). The committee was asked to determine whether there was a scientific necessity for the mouse ascites method; if so, whether the method caused pain or distress; and, if so, what could be done to minimize the pain or distress. The committee was also asked to comment on available in vitro methods; to suggest what acceptable scientific rationale, if any, there was for using the mouse ascites method; and to identify regulatory requirements for the continued use of the mouse ascites method. The committee held an open data-gathering meeting during which its members summarized data bearing on those questions. A 1-day workshop (Appendix A) was attended by 34 participants, 14 of whom made formal presentations. A second meeting was held to finalize the report. The present report was written on the basis of information in the literature and information presented at the meeting and the workshop.
Book Synopsis Tumor Targeting in Cancer Therapy by : Michel Pagé
Download or read book Tumor Targeting in Cancer Therapy written by Michel Pagé and published by Springer Science & Business Media. This book was released on 2002-04-01 with total page 773 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume introduces the principles and techniques of tumor targeting and critically surveys their applications from laboratory to bedside. By concisely synthesizing the many technical details, the authors illuminate this innovative technique, ranging from the fundamentals of drug targeting and in vivo and in vitro experimentation, to such emerging therapeutic uses as radioimmunotherapy, radioimmunodetection, therapy with cytotoxic antibodies, immunotoxins, enzyme prodrug immunotherapy, and immunotherapeutics with fusion proteins.
Book Synopsis Progress In Astronautics and Aeronautics by : F. Shahrokhi
Download or read book Progress In Astronautics and Aeronautics written by F. Shahrokhi and published by AIAA. This book was released on 1990 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Biobetters written by Amy Rosenberg and published by Springer. This book was released on 2015-08-21 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: “Biobetters: Protein Engineering to Approach the Curative” discusses the optimization of protein therapeutic products for treatment of human diseases. It is based on the fact that though numerous important therapeutic protein products have been developed for life threatening and chronic diseases that possess acceptable safety and efficacy profiles, these products have generally not been reexamined and modified for an improved clinical performance, with enhancements both to safety and efficacy profiles. Advances in protein engineering, coupled with greatly enhanced understanding of critical product quality attributes for efficacy and safety, make it possible to optimize predecessor products for clinical performance, thereby enhancing patient quality of life and with the potential for great savings in health care costs. Yet despite such knowledge, there is little movement towards such modifications. This book examines engineering protein therapeutic products such that they exhibit an optimal, not just an adequate, clinical performance profile. Two product classes, therapeutic enzymes for lysosomal storage diseases (enzyme replacement therapies, ERT) and monoclonal antibodies (mAbs), are used as examples of what modifications to such proteins could be made to enhance clinical performance, “closer to a cure” as it were. For ERT, the key to optimizing clinical performance is to ensure the ERT is endowed with moieties that target the protein to the relevant target tissue. Thus, for Gaucher Disease, our best example of how to optimize an ERT to address a disease that manifests in specific target tissues (macrophages and monocytes), the enzyme has been extensively modified to target macrophages. For diseases such as Pompe Disease, largely a disorder of muscle, optimal performance of ERT will depend on endowing the enzyme with the ability to be taken up via the Mannose 6 Phosphate Receptor, and so one of the chapters in the book will discuss such approaches. Moreover, a major failure of biotechnology based products is to gain access to the CNS, a key target tissue in numerous diseases. Thus, a chapter has been devoted to strategies to access the CNS. Additionally, immune responses to therapeutic proteins can be highly problematic, eliminating the efficacy of life saving or highly effective protein therapeutics. This is especially poignant in the case of Pompe Disease wherein great improvement in muscle strength and functionality is lost following development of an immune response to the ERT with consequent patient deterioration and death. Thus, a chapter regarding protein engineering, as well as other non-clinical approaches to diminishing immunogenicity is a valuable part of the book. Monoclonal antibodies (mAbs) can be engineered to bind targets relevant to a wide variety of diseases; binding affinity, however, is only part of the equation and one of the chapters will present a molecular assessment approach that balances affinity with pharmacokinetics and manufacturability. As with other proteins immunogenicity can be problematic, being responsible for loss of efficacy of anti-TNF mAbs, often after prolonged successful treatment. The authors will also share their perspective on the consequences of physico-chemical modifications occurring to mAbs once they reach the circulation or their target, a research area open to further development from a protein engineering as well as analytical perspective. This book will also discuss novel platforms for protein therapeutics, technologies that exceed mAbs with respect to potency, and hence, potentially efficacy. These platforms consist largely of repeat domain proteins with very high affinity for their target ligands, but while potentially more efficacious, immunogenicity may be a major problem limiting use. The economics surrounding the issue of biobetters is another high-profile issue - this final chapter will explore the incentives and disincentives for developing biobetters and consider incentives that might make their pursuit more rewarding.
