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The Highest Hit
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Book Synopsis Broadway Musicals by : Peter Filichia
Download or read book Broadway Musicals written by Peter Filichia and published by Applause Theatre & Cinema. This book was released on 2010 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: When Evita opened on Broadway during the 1979-1980 season, it was (as one of its songs said) "High Flying Adored." But in the 1970-71 season, the producers of Lolita, My Love saw their show (as one of its songs said) "Going, Gone, Gone" after its torturous Philadelphia and Boston tryouts. It didn't even try to brave Broadway, although the bookwriter-lyricist of My Fair Lady had written it. It happens every season. Broadway has one, two, or a few hit musicals, but many, many more flops. Here's a look at the extreme cases from each season of the past half-century. The musicals that everyone knew would be hits - The Sound of Music, The Phantom of the Opera, The Producers - and were. The tuners that sounded terrible from the moment they were announced - Via Galactica, The Civil War, Lestat - and turned out to be even worse than anyone expected. The shows that were destined to succeed - Breakfast at Tiffany's, 1600 Pennsylvania Avenue, Merrily We Roll Along - but didn't. The ones that didn't have a chance - Man of La Mancha, 1776, Grease - but went on to household-name status. Yes, Broadway is the oldest established permanent non-floating crap game in New York, and Peter Filichia takes a look at 100 shows that met either the most glorious or the most ignominious fates.
Download or read book The Gas Record written by and published by . This book was released on 1915 with total page 588 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Canal Record written by and published by . This book was released on 1912 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The M.S.C. Record written by and published by . This book was released on 1919 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Record of Sigma Alpha Epsilon by :
Download or read book The Record of Sigma Alpha Epsilon written by and published by . This book was released on 1916 with total page 652 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Monthly Musical Record written by and published by . This book was released on 1881 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Fragment-Based Drug Discovery by : Edward R. Zartler
Download or read book Fragment-Based Drug Discovery written by Edward R. Zartler and published by John Wiley & Sons. This book was released on 2008-11-20 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fragment-based drug discovery (FBDD) is a new paradigm in drug discovery that utilizes very small molecules - fragments of larger molecules. It is a faster, cheaper, smarter way to do drug discovery, as shown by the number of pharmaceutical companies that have embraced this approach and the biotechnology companies who use fragments as their sole source of drug discovery. Fragment-Based Drug Discovery: A Practical Approach is a guide to the techniques and practice of using fragments in drug screening. The emphasis is on practical guidance, with procedures, case studies, practical tips, and contributions from industry. Topics covered include: an introduction to fragment based drug discovery, why using fragments is a more efficient process than predominant models, and what it means to have a successful FBDD effort. setting up an FBDD project library building and production NMR in fragment screening and follow up application of protein-ligand NOE matching to the rapid evaluation of fragment binding poses target immobilized NMR screening: validation and extension to membrane proteins in situ fragment-based medicinal chemistry: screening by mass spectrometry computational approaches to fragment and substructure discovery and evaluation virtual fragment scanning: current trends, applications and web based tools fragment-based lead discovery using covalent capture methods case study from industry: the identification of high affinity beta-secretase inhibitors using fragment-based lead generation With contributions from industry experts who have successfully set up an industrial fragment-based research program, Fragment-Based Drug Discovery: A Practical Approach offers essential advice to anyone embarking on drug discovery using fragments and those looking for a new approach to screening for drugs.
Book Synopsis Evolutionary Systems Biology by : Orkun S. Soyer
Download or read book Evolutionary Systems Biology written by Orkun S. Soyer and published by Springer Science & Business Media. This book was released on 2012-07-23 with total page 459 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book aims to introduce the reader to the emerging field of Evolutionary Systems Biology, which approaches classical systems biology questions within an evolutionary framework. An evolutionary approach might allow understanding the significance of observed diversity, uncover “evolutionary design principles” and extend predictions made in model organisms to others. In addition, evolutionary systems biology can generate new insights into the adaptive landscape by combining molecular systems biology models and evolutionary simulations. This insight can enable the development of more detailed mechanistic evolutionary hypotheses.
Book Synopsis Basic Research in Parapsychology, 2d ed. by : K. Ramakrishna Rao
Download or read book Basic Research in Parapsychology, 2d ed. written by K. Ramakrishna Rao and published by McFarland. This book was released on 2001-05-14 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt: This expanded and revised text includes thirteen experimental reports (five new to this edition) and seven review articles involving meta-analysis and the assessment of evidence in specific areas of psi research. The author provides a representative sample of the extensive literature in the controversial field of parapsychology and presents a few basic experiments illustrating various procedures and broadly reflecting the major trends of psi research. Possible experimental procedures, cumulative evidence showing the replicability of individual experiments, and promising areas of psi research are also discussed. Instructors considering this book for use in a course may request an examination copy here.
Book Synopsis Knowledge Science, Engineering and Management by : Hui Xiong
Download or read book Knowledge Science, Engineering and Management written by Hui Xiong and published by Springer. This book was released on 2012-02-24 with total page 485 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the proceedings of the 5th International Conference on Knowledge Science, Engineering and Management, KSEM 2011, held in Irvine, CA, USA, in December 2011. The 34 revised full papers presented together with 7 short papers were carefully reviewed and selected from numerous submissions.
Book Synopsis PRICAI 2022: Trends in Artificial Intelligence by : Sankalp Khanna
Download or read book PRICAI 2022: Trends in Artificial Intelligence written by Sankalp Khanna and published by Springer Nature. This book was released on 2022-11-03 with total page 562 pages. Available in PDF, EPUB and Kindle. Book excerpt: This three-volume set, LNAI 13629, LNAI 13630, and LNAI 13631 constitutes the thoroughly refereed proceedings of the 19th Pacific Rim Conference on Artificial Intelligence, PRICAI 2022, held in Shangai, China, in November 10–13, 2022. The 91 full papers and 39 short papers presented in these volumes were carefully reviewed and selected from 432 submissions. PRICAI covers a wide range of topics in the areas of social and economic importance for countries in the Pacific Rim: artificial intelligence, machine learning, natural language processing, knowledge representation and reasoning, planning and scheduling, computer vision, distributed artificial intelligence, search methodologies, etc.
Book Synopsis Engineering Record, Building Record and Sanitary Engineer by : Henry Coddington Meyer
Download or read book Engineering Record, Building Record and Sanitary Engineer written by Henry Coddington Meyer and published by . This book was released on 1893 with total page 596 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The New Bill James Historical Baseball Abstract by : Bill James
Download or read book The New Bill James Historical Baseball Abstract written by Bill James and published by Simon and Schuster. This book was released on 2010-05-11 with total page 1026 pages. Available in PDF, EPUB and Kindle. Book excerpt: When Bill James published his original Historical Baseball Abstract in 1985, he produced an immediate classic, hailed by the Chicago Tribune as the “holy book of baseball.” Now, baseball's beloved “Sultan of Stats” (The Boston Globe) is back with a fully revised and updated edition for the new millennium. Like the original, The New Bill James Historical Baseball Abstract is really several books in one. The Game provides a century's worth of American baseball history, told one decade at a time, with energetic facts and figures about How, Where, and by Whom the game was played. In The Players, you'll find listings of the top 100 players at each position in the major leagues, along with James's signature stats-based ratings method called “Win Shares,” a way of quantifying individual performance and calculating the offensive and defensive contributions of catchers, pitchers, infielders, and outfielders. And there's more: the Reference section covers Win Shares for each season and each player, and even offers a Win Share team comparison. A must-have for baseball fans and historians alike, The New Bill James Historical Baseball Abstract is as essential, entertaining, and enlightening as the sport itself.
Download or read book The Hit written by Melvin Burgess and published by Scholastic Inc.. This book was released on 2014-02-25 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: “This fantasy about a drug that gives users a perfect week, then sudden death, is compelling fiction—and nearly a masterpiece.” —The Guardian A new drug is on the street. Everyone’s buzzing about it. Take the hit. Live the most intense week of your life. Then die. It’s the ultimate high at the ultimate price. Adam thinks it over. He’s poor, and doesn’t see that changing. Lizzie, his girlfriend, can’t make up her mind about sleeping with him, so he can’t get laid. His brother Jess is missing. And Manchester is in chaos, controlled by drug dealers and besieged by a group of homegrown terrorists who call themselves the Zealots. Wouldn’t one amazing week be better than this endless, penniless misery? After Adam downs one of the Death pills, he’s about to find out. “A boundary pushing thriller. . . . Amid violent action, existential anguish, and the heightened appreciation for life that death can bring, Burgess has created a premise that readers will find hard to forget.” —Publishers Weekly “Viscerally exciting and emotionally engaging. . . . A clear winner from Burgess.” —Booklist “An exciting, dark story of sex, drugs, and revolution that is sure to grip readers.” —School Library Journal
Download or read book Travelers' Record written by and published by . This book was released on 1891 with total page 758 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Oxford Handbook of Memory by : Endel Tulving
Download or read book The Oxford Handbook of Memory written by Endel Tulving and published by Oxford University Press. This book was released on 2000-05-04 with total page 715 pages. Available in PDF, EPUB and Kindle. Book excerpt: The strengths and weaknesses of human memory have fascinated people for hundreds of years, so it is not surprising that memory research has remained one of the most flourishing areas in science. During the last decade, however, a genuine science of memory has emerged, resulting in research and theories that are rich, complex, and far reaching in their implications. Endel Tulving and Fergus Craik, both leaders in memory research, have created this highly accessible guide to their field. In each chapter, eminent researchers provide insights into their particular areas of expertise in memory research. Together, the chapters in this handbook lay out the theories and presents the evidence on which they are based, highlights the important new discoveries, and defines their consequences for professionals and students in psychology, neuroscience, clinical medicine, law, and engineering.
Book Synopsis Congressional Record by : United States. Congress
Download or read book Congressional Record written by United States. Congress and published by . This book was released on 1960 with total page 1500 pages. Available in PDF, EPUB and Kindle. Book excerpt:
