The Genetics Of Pain

Download The Genetics Of Pain full books in PDF, epub, and Kindle. Read online The Genetics Of Pain ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!

The Genetics of Pain

Download The Genetics of Pain PDF Online Free

Author : Jeffrey Steven Mogil
Publisher : Progress in Pain Research and
ISBN 13 :
Total Pages : 376 pages
Book Rating : 4.3/5 (91 download)

Book Synopsis The Genetics of Pain by : Jeffrey Steven Mogil

Download or read book The Genetics of Pain written by Jeffrey Steven Mogil and published by Progress in Pain Research and. This book was released on 2004 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetics more than any other biological approach can explain why some people experience more pain than others and receive less benefit from existing analgesics. Sixteen scholarly articles from international contributors describe the application of genetic techniques to the problem of pain and consider the knowledge that has so far resulted. Three themed sections review the techniques that are allowing the study of pain mechanisms at the genetic level; describe the progress being made in lab animals and humans in identifying the genes responsible for individual differences; and explore the practical and ethical issues that face pain researchers. The editor is associated with the Centre for Research on Pain, McGill U., Montreal. Annotation : 2004 Book News, Inc., Portland, OR (booknews.com).

Chasing Men on Fire

Download Chasing Men on Fire PDF Online Free

Author : Stephen G. Waxman
Publisher : MIT Press
ISBN 13 : 0262037408
Total Pages : 320 pages
Book Rating : 4.2/5 (62 download)

Book Synopsis Chasing Men on Fire by : Stephen G. Waxman

Download or read book Chasing Men on Fire written by Stephen G. Waxman and published by MIT Press. This book was released on 2018-03-09 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: A thirty-year quest, from genes to pain-signaling neurons to people with a rare genetic disorder that makes them feel they are on fire. Two soldiers, both with wounds injuring the same nerve, show very different responses: one is disabled by neuropathic pain, unable to touch the injured limb because even the lightest contact triggers excruciating discomfort; the other notices numbness but no pain at all. Could the difference lie in their genes? In this book, described in the foreword by Nobel Laureate James Rothman as “so well written that it reads like a detective novel,” Stephen Waxman recounts the search for a gene that controls pain—a search spanning more than thirty years and three continents. The story moves from genes to pain-signaling neurons that scream when they should be silent to people with a rare genetic disorder who feel they are on fire. Waxman explains that if pain-signaling neurons are injured by trauma or disease, they can become hyperactive and send pain signals to the brain even without external stimulus. Studying the hyperactive mutant pain gene in man on fire syndrome has pointed the way to molecules that produce pain more broadly within the general population, in the rest of us. Waxman's account of the many steps that led to discovery of the pain gene tells the story behind the science, of how science happens.

Chronic Postsurgical Pain

Download Chronic Postsurgical Pain PDF Online Free

Author : Gérard Mick
Publisher : Springer Science & Business Media
ISBN 13 : 3319043226
Total Pages : 175 pages
Book Rating : 4.3/5 (19 download)

Book Synopsis Chronic Postsurgical Pain by : Gérard Mick

Download or read book Chronic Postsurgical Pain written by Gérard Mick and published by Springer Science & Business Media. This book was released on 2014-02-20 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt: Primum non nocere... The fact that a surgical procedure can leave any kind of pain casts a shadow over this tenet, which is seen as the basis of medical practice and anchor of its principle ethic... It is all the more surprising in that medicine has only paid attention to this paradoxical chronic pain situation for the past few years. Clarifying the knowledge acquired in this field has become all the more urgent for any care-giver today confronted by a legitimate request from patients: Why and how can a surgical procedure, which is supposed to bring relief, leave behind an unacceptable sequela? This is the approach which the contributors to this new subject of major clinical interest invite you to follow as you work your way through this book.

Translational Pain Research

Download Translational Pain Research PDF Online Free

Author : Lawrence Kruger
Publisher : CRC Press
ISBN 13 : 1439812101
Total Pages : 458 pages
Book Rating : 4.4/5 (398 download)

Book Synopsis Translational Pain Research by : Lawrence Kruger

Download or read book Translational Pain Research written by Lawrence Kruger and published by CRC Press. This book was released on 2009-11-24 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the Most Rapidly Advancing Fields in Modern Neuroscience The success of molecular biology and the new tools derived from molecular genetics have revolutionized pain research and its translation to therapeutic effectiveness. Bringing together recent advances in modern neuroscience regarding genetic studies in mice and humans and the practical

TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades

Download TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades PDF Online Free

Author : Wolfgang B. Liedtke, MD, PH.D.
Publisher : CRC Press
ISBN 13 : 1420005847
Total Pages : 502 pages
Book Rating : 4.4/5 (2 download)

Book Synopsis TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades by : Wolfgang B. Liedtke, MD, PH.D.

Download or read book TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades written by Wolfgang B. Liedtke, MD, PH.D. and published by CRC Press. This book was released on 2006-09-29 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the first TRP ion channel was discovered in Drosophila melanogaster in 1989, the progress made in this area of signaling research has yielded findings that offer the potential to dramatically impact human health and wellness. Involved in gateway activity for all five of our senses, TRP channels have been shown to respond to a wide range of st

Pain Management and the Opioid Epidemic

Download Pain Management and the Opioid Epidemic PDF Online Free

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309459575
Total Pages : 483 pages
Book Rating : 4.3/5 (94 download)

Book Synopsis Pain Management and the Opioid Epidemic by : National Academies of Sciences, Engineering, and Medicine

Download or read book Pain Management and the Opioid Epidemic written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-09-28 with total page 483 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.

Pain Genetics

Download Pain Genetics PDF Online Free

Author : Inna Belfer
Publisher : John Wiley & Sons
ISBN 13 : 9781118398845
Total Pages : 0 pages
Book Rating : 4.3/5 (988 download)

Book Synopsis Pain Genetics by : Inna Belfer

Download or read book Pain Genetics written by Inna Belfer and published by John Wiley & Sons. This book was released on 2014-02-03 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pain Genetics: Basic to Translational Science is a timely synthesis of the key areas of research informing our understanding of the genetic basis of pain. The book opens with foundational information on basic genetic mechanisms underlying pain perception and progresses recently discovered complex concepts facing the field. The coverage is wide-ranging and will serves as an excellent entry point into understating the genetics of pain as well as providing a single resource for established researchers looking for a better understanding of the diverse strands of research going on in the area. With contributors painstakingly selected to provide a broad range of perspectives and research, Pain Genetics will be a valuable resource for geneticists, neuroscientists, and biomedical professionals alike.

Functional Pain Syndromes

Download Functional Pain Syndromes PDF Online Free

Author : Emeran A. Mayer
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1496332008
Total Pages : 643 pages
Book Rating : 4.4/5 (963 download)

Book Synopsis Functional Pain Syndromes by : Emeran A. Mayer

Download or read book Functional Pain Syndromes written by Emeran A. Mayer and published by Lippincott Williams & Wilkins. This book was released on 2015-06-01 with total page 643 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores the connection of functional pain syndromes (e.g., irritable bowel syndrome and fibromyalgia) with anxiety, depression, chronic fatigue syndrome, and posttraumatic stress disorder. The authors address possible common pathophysiologies and review a range of treatment options, from antidepressants to cognitive-behavioral therapy. Who should buy this book? Whether you are a general practitioner, specialist, or scientist, this book is essential reading. It sheds new light on the complex links between various painful syndromes and disorders.

Relieving Pain in America

Download Relieving Pain in America PDF Online Free

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 030921484X
Total Pages : 383 pages
Book Rating : 4.3/5 (92 download)

Book Synopsis Relieving Pain in America by : Institute of Medicine

Download or read book Relieving Pain in America written by Institute of Medicine and published by National Academies Press. This book was released on 2011-10-26 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic pain costs the nation up to $635 billion each year in medical treatment and lost productivity. The 2010 Patient Protection and Affordable Care Act required the Department of Health and Human Services (HHS) to enlist the Institute of Medicine (IOM) in examining pain as a public health problem. In this report, the IOM offers a blueprint for action in transforming prevention, care, education, and research, with the goal of providing relief for people with pain in America. To reach the vast multitude of people with various types of pain, the nation must adopt a population-level prevention and management strategy. The IOM recommends that HHS develop a comprehensive plan with specific goals, actions, and timeframes. Better data are needed to help shape efforts, especially on the groups of people currently underdiagnosed and undertreated, and the IOM encourages federal and state agencies and private organizations to accelerate the collection of data on pain incidence, prevalence, and treatments. Because pain varies from patient to patient, healthcare providers should increasingly aim at tailoring pain care to each person's experience, and self-management of pain should be promoted. In addition, because there are major gaps in knowledge about pain across health care and society alike, the IOM recommends that federal agencies and other stakeholders redesign education programs to bridge these gaps. Pain is a major driver for visits to physicians, a major reason for taking medications, a major cause of disability, and a key factor in quality of life and productivity. Given the burden of pain in human lives, dollars, and social consequences, relieving pain should be a national priority.

An Introduction to Pain and its relation to Nervous System Disorders

Download An Introduction to Pain and its relation to Nervous System Disorders PDF Online Free

Author : Anna A. Battaglia
Publisher : John Wiley & Sons
ISBN 13 : 1118455975
Total Pages : 453 pages
Book Rating : 4.1/5 (184 download)

Book Synopsis An Introduction to Pain and its relation to Nervous System Disorders by : Anna A. Battaglia

Download or read book An Introduction to Pain and its relation to Nervous System Disorders written by Anna A. Battaglia and published by John Wiley & Sons. This book was released on 2016-05-02 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction to Pain and its relation to Nervous System Disorders provides an accessible overview of the latest developments in the science underpinning pain research, including, but not limited to, the physiological, pathological and psychological aspects. This unique book fills a gap in current literature by focussing on the intricate relationship between pain and human nervous system disorders such as Autism, Alzheimer Disease, Parkinson’s Disease, Depression and Multiple Sclerosis. This fully illustrated, colour handbook will help non-experts, including advanced undergraduate and new postgraduate students, become familiar with the current, wide-ranging areas of research that cover every aspect of the field from chronic and inflammatory pain to neuropathic pain and biopsychosocial models of pain, functional imaging and genetics. Contributions from leading experts in neuroscience and psychiatry provide both factual information and critical points of view on their approach and the theoretical framework behind their choices. An appreciation of the strengths and weaknesses of brain imaging technology applied to pain research in humans provides the tools required to understand current cutting edge literature on the topic. Chapters covering placebo effects in analgesia and the psychology of pain give a thorough overview of cognitive, psychological and social influences on pain perception. Sections exploring pain in the lifecycle and in relation to nervous system disorders take particular relevance from a clinical point of view. Furthermore, an intellectually stimulating chapter analysing the co-morbidity of pain and depression provides a philosophical angle rarely presented in related handbooks. The references to external research databases and relevant websites aim to prompt readers to become critical and independent thinkers, and motivate them to carry out further reading on these topics. Introduction to Pain and its relation to Nervous System Disorders is essential reading for advanced undergraduate and postgraduate students in neuroscience, medical and biomedical sciences, as well as for clinical and medical healthcare professionals involved in pain management.

Genomics of Pain and Co-Morbid Symptoms

Download Genomics of Pain and Co-Morbid Symptoms PDF Online Free

Author : Susan G. Dorsey
Publisher : Springer Nature
ISBN 13 : 3030216578
Total Pages : 254 pages
Book Rating : 4.0/5 (32 download)

Book Synopsis Genomics of Pain and Co-Morbid Symptoms by : Susan G. Dorsey

Download or read book Genomics of Pain and Co-Morbid Symptoms written by Susan G. Dorsey and published by Springer Nature. This book was released on 2020-06-15 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an overview of the field of pain genomics and the genomics of related, or co-occuring, symptoms, the current state-of-the-science, and challenges that remain. It brings differing views in the field together and provides examples of translational science from using cellular and rodent models to human clinical trials. This book's structure leads the reader through the physiology of pain and genomics into how pain is studied, mechanisms of acute and chronic pain, various protocols that are used throughout the field along with the pros/cons of the current methods used, and project into the future of pain genomics. This work is intended for classroom teaching, for nurses, for novice researchers in symptom science and pain research as well as students and postdoctoral fellows.

Acute Pain Management

Download Acute Pain Management PDF Online Free

Author : Raymond S. Sinatra
Publisher : Cambridge University Press
ISBN 13 : 0521874912
Total Pages : 729 pages
Book Rating : 4.5/5 (218 download)

Book Synopsis Acute Pain Management by : Raymond S. Sinatra

Download or read book Acute Pain Management written by Raymond S. Sinatra and published by Cambridge University Press. This book was released on 2009-04-27 with total page 729 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook provides an overview of pain management useful to specialists as well as non-specialists, surgeons, and nursing staff.

Chronic Pain Epidemiology

Download Chronic Pain Epidemiology PDF Online Free

Author : Peter Croft
Publisher : Oxford University Press, USA
ISBN 13 : 0199235767
Total Pages : 377 pages
Book Rating : 4.1/5 (992 download)

Book Synopsis Chronic Pain Epidemiology by : Peter Croft

Download or read book Chronic Pain Epidemiology written by Peter Croft and published by Oxford University Press, USA. This book was released on 2010-09-30 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an invaluable framework and basis for thinking about chronic pain and the potential for its prevention in public health terms.

The Oxford Handbook of the Neurobiology of Pain

Download The Oxford Handbook of the Neurobiology of Pain PDF Online Free

Author : John N. Wood
Publisher :
ISBN 13 : 0190860502
Total Pages : 939 pages
Book Rating : 4.1/5 (98 download)

Book Synopsis The Oxford Handbook of the Neurobiology of Pain by : John N. Wood

Download or read book The Oxford Handbook of the Neurobiology of Pain written by John N. Wood and published by . This book was released on 2020 with total page 939 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook is currently in development, with individual articles publishing online in advance of print publication. At this time, we cannot add information about unpublished articles in this handbook, however the table of contents will continue to grow as additional articles pass through the review process and are added to the site. Please note that the online publication date for this handbook is the date that the first article in the title was published online.

Epigenetics of Chronic Pain

Download Epigenetics of Chronic Pain PDF Online Free

Author :
Publisher : Academic Press
ISBN 13 : 0128140712
Total Pages : 250 pages
Book Rating : 4.1/5 (281 download)

Book Synopsis Epigenetics of Chronic Pain by :

Download or read book Epigenetics of Chronic Pain written by and published by Academic Press. This book was released on 2018-10-29 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epigenetics of Chronic Pain, Volume Nine, presents comprehensive information on the role of epigenetics in chronic pain sensitivity, providing a detailed, but accessible, view of the field from basic principles, to clinical application. Leading international researchers discuss essential mechanisms of chronic pain epigenetics, including the molecular processes of chromatin remodeling, histone modifications, and the microRNAs and noncoding RNAs involved in regulating genes tied to pain sensitivity. The influence of epigenetics in inflammatory, neuropathic, visceral and other pain models is examined, with data derived from epigenetic studies on peripheral and central mechanisms of pain sensitivity in animal models and clinical cases studies. The studies and case examples cited highlight therapeutic pathways of significance and next steps for researchers to develop epigenetic-based treatments for chronic pain. In recent years, epigenetic regulation of gene expression has been shown to play a central role in managing human pain sensitivity. Findings show that expression of many genes critical to increases or decreases in pain sensitivity are indeed regulated by DNA methylation and its enzymes, histone-involved chromatin remodeling, and noncoding RNAs, mainly microRNAs. - Compiles all known information on epigenetic regulation of chronic pain in one volume - Covers the basic functionality of epigenetic mechanisms involved in pain management, applications of recent research in understanding different types of chronic pain, and pathways for developing therapeutics - Leading international researchers from across academia, clinical settings, and the pharmaceutical industry discuss epigenetics in inflammatory, neuropathic, visceral, and other pain models in-depth - Enables clinicians, researchers, and pharmacologists to better understand and treat chronic pain

The Politics of Pain Medicine

Download The Politics of Pain Medicine PDF Online Free

Author : S. Scott Graham
Publisher : University of Chicago Press
ISBN 13 : 022626405X
Total Pages : 253 pages
Book Rating : 4.2/5 (262 download)

Book Synopsis The Politics of Pain Medicine by : S. Scott Graham

Download or read book The Politics of Pain Medicine written by S. Scott Graham and published by University of Chicago Press. This book was released on 2015-11-17 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: The author explores the changing rhetoric of pain medicine and how this rhetoric ultimately shapes the health-care community's understanding of what pain medicine is, how the medicine should be practiced and regulated, and how practitioner-patient relationships are best managed. -- Dust jacket.

Temporomandibular Disorders and Related Pain Conditions

Download Temporomandibular Disorders and Related Pain Conditions PDF Online Free

Author : Barry J. Sessle
Publisher : Progress in Pain Research and
ISBN 13 :
Total Pages : 520 pages
Book Rating : 4.3/5 (91 download)

Book Synopsis Temporomandibular Disorders and Related Pain Conditions by : Barry J. Sessle

Download or read book Temporomandibular Disorders and Related Pain Conditions written by Barry J. Sessle and published by Progress in Pain Research and. This book was released on 1995 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: