The Genealogy Of A Gene

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The Family Gene

Author : Joselin Linder
Publisher : HarperCollins
ISBN 13 : 0062378929
Total Pages : 245 pages
Book Rating : 4.0/5 (623 download)

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Book Synopsis The Family Gene by : Joselin Linder

Download or read book The Family Gene written by Joselin Linder and published by HarperCollins. This book was released on 2017-03-14 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: A riveting medical mystery about a young woman’s quest to uncover the truth about her likely fatal genetic disorder that opens a window onto the exploding field of genomic medicine When Joselin Linder was in her twenties her legs suddenly started to swell. After years of misdiagnoses, doctors discovered a deadly blockage in her liver. Struggling to find an explanation for her unusual condition, Joselin compared the medical chart of her father—who had died from a mysterious disease, ten years prior—with that of an uncle who had died under similarly strange circumstances. Delving further into the past, she discovered that her great-grandmother had displayed symptoms similar to hers before her death. Clearly, this was more than a fluke. Setting out to build a more complete picture of the illness that haunted her family, Joselin approached Dr. Christine Seidman, the head of a group of world-class genetic researchers at Harvard Medical School, for help. Dr. Seidman had been working on her family’s case for twenty years and had finally confirmed that fourteen of Joselin’s relatives carried something called a private mutation—meaning that they were the first known people to experience the baffling symptoms of a brand new genetic mutation. Here, Joselin tells the story of their gene: the lives it claimed and the future of genomic medicine with the potential to save those that remain. Digging into family records and medical history, conducting interviews with relatives and friends, and reflecting on her own experiences with the Harvard doctor, Joselin pieces together the lineage of this deadly gene to write a gripping and unforgettable exploration of family, history, and love. A compelling chronicle of survival and perseverance, The Family Gene is an important story of a young woman reckoning with her father’s death, her own mortality, and her ethical obligations to herself and those closest to her.

The Genealogy of a Gene

Author : Myles W. Jackson
Publisher : MIT Press
ISBN 13 : 0262028662
Total Pages : 349 pages
Book Rating : 4.2/5 (62 download)

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Book Synopsis The Genealogy of a Gene by : Myles W. Jackson

Download or read book The Genealogy of a Gene written by Myles W. Jackson and published by MIT Press. This book was released on 2015-02-20 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: The history of the CCR5 gene as a lens through which to view such issues as intellectual property, Big Pharma, personalized medicine, and race and genomics. In The Genealogy of a Gene, Myles Jackson uses the story of the CCR5 gene to investigate the interrelationships among science, technology, and society. Mapping the varied “genealogy” of CCR5—intellectual property, natural selection, Big and Small Pharma, human diversity studies, personalized medicine, ancestry studies, and race and genomics—Jackson links a myriad of diverse topics. The history of CCR5 from the 1990s to the present offers a vivid illustration of how intellectual property law has changed the conduct and content of scientific knowledge, and the social, political, and ethical implications of such a transformation. The CCR5 gene began as a small sequence of DNA, became a patented product of a corporation, and then, when it was found to be an AIDS virus co-receptor with a key role in the immune system, it became part of the biomedical research world—and a potential moneymaker for the pharmaceutical industry. When it was further discovered that a mutation of the gene found in certain populations conferred near-immunity to the AIDS virus, questions about race and genetics arose. Jackson describes these developments in the context of larger issues, including the rise of “biocapitalism,” the patentability of products of nature, the difference between U.S. and European patenting approaches, and the relevance of race and ethnicity to medical research.

Trace Your Roots with DNA

Author : Megan Smolenyak
Publisher : Rodale
ISBN 13 : 1594860068
Total Pages : 290 pages
Book Rating : 4.5/5 (948 download)

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Book Synopsis Trace Your Roots with DNA by : Megan Smolenyak

Download or read book Trace Your Roots with DNA written by Megan Smolenyak and published by Rodale. This book was released on 2004-10-27 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: Two leading genealogists explain how the latest techniques in genetic testing can help readers research their ancestry and family history, discussing what kind of information DNA testing can provide, how to interpret the results, what is and is not possible with genetic testing, and more. Original. 15,000 first printing.

The Genealogical Science

Author : Nadia Abu El-Haj
Publisher : University of Chicago Press
ISBN 13 : 0226201406
Total Pages : 323 pages
Book Rating : 4.2/5 (262 download)

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Book Synopsis The Genealogical Science by : Nadia Abu El-Haj

Download or read book The Genealogical Science written by Nadia Abu El-Haj and published by University of Chicago Press. This book was released on 2012-04-26 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume analyses the scientific work and social implications of the flourishing field of genetic history. The author examines genetic history's working assumptions about culture and nature, identity and biology, and the individual and the collective.

Genetic Genealogy

Author : Emily D. Aulicino
Publisher : Author House
ISBN 13 : 1491840897
Total Pages : 263 pages
Book Rating : 4.4/5 (918 download)

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Book Synopsis Genetic Genealogy by : Emily D. Aulicino

Download or read book Genetic Genealogy written by Emily D. Aulicino and published by Author House. This book was released on 2013-12-19 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt: Finally, in the rapidly evolving field of genetic genealogy an up-to-date resource is here! A Genetic Genealogy Handbook: The Basics and Beyond provides genealogists with the knowledge and confidence to use DNA testing for family research. The book guides genealogists in understanding various tests and determining what DNA segments came from which ancestor. The book explains how DNA testing helps when written records stop and discusses how testing proves or disprove oral family history. Learn which tests help adoptees; understand why you resemble your relatives and how testing can connect you with cousins you never knew. Discover how to encourage potential cousins to test and learn guidelines for becoming a project administrator, genetic genealogy speaker or facilitator for your genealogical societys DNA interest group. A Genetic Genealogy Handbook: The Basics and Beyond helps experienced and fledgling researchers become genetic genealogists able to use DNA testing to resolve genealogical roadblocks.

The Family Tree Guide to DNA Testing and Genetic Genealogy

Author : Blaine T. Bettinger
Publisher : Penguin
ISBN 13 : 1440300577
Total Pages : 274 pages
Book Rating : 4.4/5 (43 download)

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Book Synopsis The Family Tree Guide to DNA Testing and Genetic Genealogy by : Blaine T. Bettinger

Download or read book The Family Tree Guide to DNA Testing and Genetic Genealogy written by Blaine T. Bettinger and published by Penguin. This book was released on 2019-08-13 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: Unlock the family secrets in your DNA! Discover the answers to your family history mysteries using the most cutting edge tool available. This plain-English guide (newly updated and expanded to include th latest DNA developments) will teach you what DNA tests are available; the pros and cons of the major testing companies; and how to choose the right test to answer your specific genealogy questions. And once you've taken a DNA test, this guide will help you use your often-overwhelming results, with tips for understanding ethnicity estimates, navigating suggested cousin matches, and using third-party tools like GEDmatch to further analyze your data. The book features: · Colorful diagrams and expert definitions that explain key DNA terms and concepts such as haplogroups and DNA inheritance patterns · Detailed guides to each of the major kinds of DNA tests and tips for selecting the DNA test that can best help you solve your family mysteries, with case studies showing how each can be useful · Information about third-party tools you can use to more thoroughly analyze your test results once you've received them · Test comparison guides and research forms to help you select the most appropriate DNA test and organize your results · Insights into how adoptees and others who know little about their ancestry can benefit from DNA testing Whether you've just heard of DNA testing or you've tested at all three major companies, this guide will give you the tools you need to unpuzzle your DNA and discover what it can tell you about your family tree.

The Practical Guide to the Genetic Family History

Author : Robin L. Bennett
Publisher : John Wiley & Sons
ISBN 13 : 1118209818
Total Pages : 389 pages
Book Rating : 4.1/5 (182 download)

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Book Synopsis The Practical Guide to the Genetic Family History by : Robin L. Bennett

Download or read book The Practical Guide to the Genetic Family History written by Robin L. Bennett and published by John Wiley & Sons. This book was released on 2011-09-20 with total page 389 pages. Available in PDF, EPUB and Kindle. Book excerpt: HELPS YOU DEVELOP AND ASSESS PEDIGREES TO MAKE DIAGNOSES, EVALUATE RISK, AND COUNSEL PATIENTS The Second Edition of The Practical Guide to the Genetic Family History not only shows how to take a medical-family history and record a pedigree, but also explains why each bit of information gathered is important. It provides essential support in diagnosing conditions with a genetic component. Moreover, it aids in recommending genetic testing, referring patients for genetic counseling, determining patterns of inheritance, calculating risk of disease, making decisions for medical management and surveillance, and informing and educating patients. Based on the author's twenty-five years as a genetic counselor, the book also helps readers deal with the psychological, social, cultural, and ethical problems that arise in gathering a medical-family history and sharing findings with patients. Featuring a new Foreword by Arno Motulsky, widely recognized as the founder of medical genetics, and completely updated to reflect the most recent findings in genetic medicine, this Second Edition presents the latest information and methods for preparing and assessing a pedigree, including: Value and utility of a thorough medical-family history Directed questions to ask when developing a medical-family history for specific disease conditions Use of pedigrees to identify individuals with an increased susceptibility to cancer Verification of family medical information Special considerations when adoptions or gamete donors are involved Ethical issues that may arise in recording a pedigree Throughout the book, clinical examples based on hypothetical families illustrate key concepts, helping readers understand how real issues present themselves and how they can be resolved. This book will enable all healthcare providers, including physicians, nurses, medical social workers, and physician assistants, as well as genetic counselors, to take full advantage of the pedigree as a primary tool for making a genetic risk assessment and providing counseling for patients and their families.

The Invisible History of the Human Race

Author : Christine Kenneally
Publisher : ReadHowYouWant.com
ISBN 13 : 1458798704
Total Pages : 391 pages
Book Rating : 4.4/5 (587 download)

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Book Synopsis The Invisible History of the Human Race by : Christine Kenneally

Download or read book The Invisible History of the Human Race written by Christine Kenneally and published by ReadHowYouWant.com. This book was released on 2015-01-29 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: A New York Times Notable Book of 2014 We are doomed to repeat history if we fail to learn from it, but how are we affected by the forces that are invisible to us? What role does Neanderthal DNA play in our genetic makeup? How did the theory of eugenics embraced by Nazi Germany first develop? How is trust passed down in Africa, and silence inherited in Tasmania? How are private companies like Ancestry.com uncovering, preserving and potentially editing the past? In The Invisible History of the Human Race, Christine Kenneally reveals that, remarkably, it is not only our biological history that is coded in our DNA, but also our social history. She breaks down myths of determinism and draws on cutting - edge research to explore how both historical artefacts and our DNA tell us where we have come from and where we may be going.

The Stranger in My Genes

Author : Bill Griffeth
Publisher : New England Historic Genealogical Society
ISBN 13 : 088082350X
Total Pages : 198 pages
Book Rating : 4.8/5 (88 download)

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Book Synopsis The Stranger in My Genes by : Bill Griffeth

Download or read book The Stranger in My Genes written by Bill Griffeth and published by New England Historic Genealogical Society. This book was released on 2016-09-06 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bill Griffeth, longtime genealogy buff, takes a DNA test that has an unexpected outcome: "If the results were correct, it meant that the family tree I had spent years documenting was not my own." Bill undertakes a quest to solve the mystery of his origins, which shakes his sense of identity. As he takes us on his journey, we learn about choices made by his ancestors, parents, and others - and we see Bill measure and weigh his own difficult choices as he confronts the past.

NextGen Genealogy

Author : David R. Dowell Ph.D.
Publisher : Bloomsbury Publishing USA
ISBN 13 :
Total Pages : 276 pages
Book Rating : 4.2/5 (161 download)

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Book Synopsis NextGen Genealogy by : David R. Dowell Ph.D.

Download or read book NextGen Genealogy written by David R. Dowell Ph.D. and published by Bloomsbury Publishing USA. This book was released on 2014-11-25 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: DNA testing can serve as a powerful tool that unlocks the hidden information within our bodies for family history research. This book explains how genetic genealogy works and answers the questions of genealogists and individuals seeking information on their family trees. Now that DNA testing for genealogical purposes has existed for nearly a decade and a half—and been refined and improved during that time—it has established its value among family history researchers. It is now becoming accepted as another tool in the kit of well-rounded genealogists. This book covers this fast-growing application of genetics, empowering genealogists to apply this information to further their research. It will also enable general readers to understand how genetic information can be applied to verify or refute documentary research—and to break down frustrating walls that block the discovery of ancestors. The book describes the three major categories of DNA testing for family history research: Y-chromosome tests for investigating paternal (surname) lines, mitochondrial tests for investigating maternal (umbilical) lines, and autosomal tests for exploring close relationships. Expert genealogist David Dowell provides guidance on deciding which test to take and identifying which members of your family should be tested to answer your most important genealogical questions. Readers will also learn how to interpret the results of tests and methods for further analysis to get additional value from them.

DNA and Genealogy

Author : Colleen Fitzpatrick
Publisher : Mitchell Beazley
ISBN 13 :
Total Pages : 192 pages
Book Rating : 4.:/5 (89 download)

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Book Synopsis DNA and Genealogy by : Colleen Fitzpatrick

Download or read book DNA and Genealogy written by Colleen Fitzpatrick and published by Mitchell Beazley. This book was released on 2005 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The genetic trail an ancestor leaves behind is every bit as important as his paper trail. Though Y-chromosome and mitochondrial DNA testing, the modern genealogist has a powerful new tool for researching his roots" -- back cover.

DNA USA: A Genetic Portrait of America

Author : Bryan Sykes
Publisher : W. W. Norton & Company
ISBN 13 : 0871404761
Total Pages : 384 pages
Book Rating : 4.8/5 (714 download)

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Book Synopsis DNA USA: A Genetic Portrait of America by : Bryan Sykes

Download or read book DNA USA: A Genetic Portrait of America written by Bryan Sykes and published by W. W. Norton & Company. This book was released on 2012-05-14 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Crisscrossing the continent, a renowned geneticist provides a groundbreaking examination of America through its DNA. The best-selling author of The Seven Daughters of Eve now turns his sights on the United States, one of the most genetically variegated countries in the world. From the blue-blooded pockets of old-WASP New England to the vast tribal lands of the Navajo, Bryan Sykes takes us on a historical genetic tour, interviewing genealogists, geneticists, anthropologists, and everyday Americans with compelling ancestral stories. His findings suggest: • Of Americans whose ancestors came as slaves, virtually all have some European DNA. • Racial intermixing appears least common among descendants of early New England colonists. • There is clear evidence of Jewish genes among descendants of southwestern Spanish Catholics. • Among white Americans, evidence of African DNA is most common in the South. • European genes appeared among Native Americans as early as ten thousand years ago. An unprecedented look into America's genetic mosaic and how we perceive race, DNA USA challenges the very notion of what we think it means to be American.

DNA

Author : Jim Ollhoff
Publisher : ABDO
ISBN 13 : 9781616134624
Total Pages : 40 pages
Book Rating : 4.1/5 (346 download)

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Book Synopsis DNA by : Jim Ollhoff

Download or read book DNA written by Jim Ollhoff and published by ABDO. This book was released on 2011 with total page 40 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interest in family history is at its highest. Young people want to know where they came from, as well as the people who built their family and their country. Genetic Genealogy is an exciting new field that can help in tracing lineage and finding a haplogroup to see where a person's ancestors traveled. DNA: Window to the Past explains all about genetic genealogy, what is DNA, why it is important, and how it can be useful in learning more about a person's heritage. Readers explore their own and other people's pasts, creating an understanding of the opportunities and challenges that built this nation. ABDO & Daughters is an imprint of ABDO Publishing Company.

The Cooking Gene

Author : Michael W. Twitty
Publisher : HarperCollins
ISBN 13 : 0062876570
Total Pages : 504 pages
Book Rating : 4.0/5 (628 download)

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Book Synopsis The Cooking Gene by : Michael W. Twitty

Download or read book The Cooking Gene written by Michael W. Twitty and published by HarperCollins. This book was released on 2018-07-31 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: 2018 James Beard Foundation Book of the Year | 2018 James Beard Foundation Book Award Winner inWriting | Nominee for the 2018 Hurston/Wright Legacy Award in Nonfiction | #75 on The Root100 2018 A renowned culinary historian offers a fresh perspective on our most divisive cultural issue, race, in this illuminating memoir of Southern cuisine and food culture that traces his ancestry—both black and white—through food, from Africa to America and slavery to freedom. Southern food is integral to the American culinary tradition, yet the question of who "owns" it is one of the most provocative touch points in our ongoing struggles over race. In this unique memoir, culinary historian Michael W. Twitty takes readers to the white-hot center of this fight, tracing the roots of his own family and the charged politics surrounding the origins of soul food, barbecue, and all Southern cuisine. From the tobacco and rice farms of colonial times to plantation kitchens and backbreaking cotton fields, Twitty tells his family story through the foods that enabled his ancestors’ survival across three centuries. He sifts through stories, recipes, genetic tests, and historical documents, and travels from Civil War battlefields in Virginia to synagogues in Alabama to Black-owned organic farms in Georgia. As he takes us through his ancestral culinary history, Twitty suggests that healing may come from embracing the discomfort of the Southern past. Along the way, he reveals a truth that is more than skin deep—the power that food has to bring the kin of the enslaved and their former slaveholders to the table, where they can discover the real America together. Illustrations by Stephen Crotts

Genealogical Genetic Structure

Author : C. Cannings
Publisher : Cambridge University Press
ISBN 13 : 9780521239462
Total Pages : 172 pages
Book Rating : 4.2/5 (394 download)

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Book Synopsis Genealogical Genetic Structure by : C. Cannings

Download or read book Genealogical Genetic Structure written by C. Cannings and published by Cambridge University Press. This book was released on 1981-11-26 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although the long-term processes of evolution are selection and mutation, the infrastructure of a population is a no less important force in determining the distributions of genetic characteristics observable within populations. In small populations, and in particular in human populations, complex patterns of genealogical relationship between individuals can be an important factor in the maintenance of genetic variability. The aim of this book is to develop the quantitative theory of the interrelationship between the genealogical and the genetic structures of a population. Aspects of other structural features, such as migration patterns, are also discussed, but are not central to the development. There are three major aspects; each comprises two chapters of the text. First, genealogical relationships are characterized in a way which can illuminate their genetic consequences. Second, the evolutionary aspects of genealogical structure are developed. Finally, the last two chapters present methods of characterizing the complete structure of a genealogy, and of computing relevant parameters of genealogical structure; these topics are of relevance to genetic epidemiology as well as to population genetics.

The Genes in Your Genealogy --

Author : Sherilyn Bell
Publisher :
ISBN 13 : 9781894018845
Total Pages : 176 pages
Book Rating : 4.0/5 (188 download)

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Book Synopsis The Genes in Your Genealogy -- by : Sherilyn Bell

Download or read book The Genes in Your Genealogy -- written by Sherilyn Bell and published by . This book was released on 2001 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Gene Genealogies, Variation and Evolution: A primer in coalescent theory

Author : Jotun Hein
Publisher : Oxford University Press, USA
ISBN 13 : 9780191546150
Total Pages : 298 pages
Book Rating : 4.5/5 (461 download)

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Book Synopsis Gene Genealogies, Variation and Evolution: A primer in coalescent theory by : Jotun Hein

Download or read book Gene Genealogies, Variation and Evolution: A primer in coalescent theory written by Jotun Hein and published by Oxford University Press, USA. This book was released on 2004-12-09 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: Authored by leading experts, this seminal text presents a straightforward and elementary account of coalescent theory, which is a central concept in the study of genetic sequence variation observed in a population. Rich in examples and illustrations it is ideal for a graduate course in statistics, population, molecular and medical genetics, bioscience and medicine, and for students studying the evolution of human population and disease. It is also an invaluable reference for bioscientists and statisticians in the pharmaceutical industry and academia - ;Coalescent theory is a central concept in the study of genetic sequence variation that probabilistically describes the genealogy relating the sampled sequences. In this text, besides fulfilling the glaring need for such a book, the authors present this theory in a straightforward and elementary manner and describe the statistical and computational methods used in modelling and analyzing genetic sequence variation. Rich in examples and illustrations the book covers basic concepts, complications arising from geographical structure and recombination before considering aspects of statistical inference based on these models. The book ends with chapters on Gene Mapping, which combines sequence variation data with phenotypic data (such as disease) to define areas of the genome where genes are responsible for the trait, and Human Evolution, a research area that is experiencing a renaissance due to the enormous amounts of data produced in molecular studies. Authored by leading experts, this seminal text presents a straightforward and elementary account of coalescent theory, which is a central concept in the study of genetic sequence variation observed in a population. It is highly suitable for a graduate course in statistics, population, molecular and medical genetics, bioscience and medicine and students studying the evolution of human population and disease, and will be an invaluable reference for bioscientists and statisticians in the pharmaceutical industry and academia - ;an excellent and timely book that should appeal to a variety of people in genetics and applied mathematics. - Professor Montgomery Slatkin (Berkeley);the authors are outstanding experts in the field, and the book is topical and timely. - Professor David Balding (Imperial College);Hein, Schierup and Wiuf have written the first general book on the coalescent. It is an engaging combination of clear mathematical derivation and real data examples. - Professor Joe Felsenstein (University of Washington)