The Gene Ontology Handbook

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The Gene Ontology Handbook

Author : Christophe Dessimoz
Publisher :
ISBN 13 : 9781013267710
Total Pages : 298 pages
Book Rating : 4.2/5 (677 download)

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Book Synopsis The Gene Ontology Handbook by : Christophe Dessimoz

Download or read book The Gene Ontology Handbook written by Christophe Dessimoz and published by . This book was released on 2020-10-08 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a practical and self-contained overview of the Gene Ontology (GO), the leading project to organize biological knowledge on genes and their products across genomic resources. Written for biologists and bioinformaticians, it covers the state-of-the-art of how GO annotations are made, how they are evaluated, and what sort of analyses can and cannot be done with the GO. In the spirit of the Methods in Molecular Biology book series, there is an emphasis throughout the chapters on providing practical guidance and troubleshooting advice. Authoritative and accessible, The Gene Ontology Handbook serves non-experts as well as seasoned GO users as a thorough guide to this powerful knowledge system. This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors.

The Gene Ontology Handbook

Author : Christophe Dessimoz
Publisher : Humana
ISBN 13 : 9781493981267
Total Pages : 305 pages
Book Rating : 4.9/5 (812 download)

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Book Synopsis The Gene Ontology Handbook by : Christophe Dessimoz

Download or read book The Gene Ontology Handbook written by Christophe Dessimoz and published by Humana. This book was released on 2018-06-23 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is open access under a CC BY 4.0 license. This book provides a practical and self-contained overview of the Gene Ontology (GO), the leading project to organize biological knowledge on genes and their products across genomic resources. Written for biologists and bioinformaticians, it covers the state-of-the-art of how GO annotations are made, how they are evaluated, and what sort of analyses can and cannot be done with the GO. In the spirit of the Methods in Molecular Biology book series, there is an emphasis throughout the chapters on providing practical guidance and troubleshooting advice. Authoritative and accessible, The Gene Ontology Handbook serves non-experts as well as seasoned GO users as a thorough guide to this powerful knowledge system.

Handbook Of Metadata, Semantics And Ontologies

Author : Miguel-angel Sicilia
Publisher : World Scientific
ISBN 13 : 9814590355
Total Pages : 579 pages
Book Rating : 4.8/5 (145 download)

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Book Synopsis Handbook Of Metadata, Semantics And Ontologies by : Miguel-angel Sicilia

Download or read book Handbook Of Metadata, Semantics And Ontologies written by Miguel-angel Sicilia and published by World Scientific. This book was released on 2013-12-17 with total page 579 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metadata research has emerged as a discipline cross-cutting many domains, focused on the provision of distributed descriptions (often called annotations) to Web resources or applications. Such associated descriptions are supposed to serve as a foundation for advanced services in many application areas, including search and location, personalization, federation of repositories and automated delivery of information. Indeed, the Semantic Web is in itself a concrete technological framework for ontology-based metadata. For example, Web-based social networking requires metadata describing people and their interrelations, and large databases with biological information use complex and detailed metadata schemas for more precise and informed search strategies.There is a wide diversity in the languages and idioms used for providing meta-descriptions, from simple structured text in metadata schemas to formal annotations using ontologies, and the technologies for storing, sharing and exploiting meta-descriptions are also diverse and evolve rapidly. In addition, there is a proliferation of schemas and standards related to metadata, resulting in a complex and moving technological landscape — hence, the need for specialized knowledge and skills in this area.The Handbook of Metadata, Semantics and Ontologies is intended as an authoritative reference for students, practitioners and researchers, serving as a roadmap for the variety of metadata schemas and ontologies available in a number of key domain areas, including culture, biology, education, healthcare, engineering and library science.

Regulation of Gene Expression by Small RNAs

Author : Rajesh K. Gaur
Publisher : CRC Press
ISBN 13 : 1420008706
Total Pages : 460 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Regulation of Gene Expression by Small RNAs by : Rajesh K. Gaur

Download or read book Regulation of Gene Expression by Small RNAs written by Rajesh K. Gaur and published by CRC Press. This book was released on 2009-04-27 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: New Findings Revolutionize Concepts of Gene FunctionEndogenous small RNAs have been found in various organisms, including humans, mice, flies, worms, fungi, and bacteria. Furthermore, it's been shown that microRNAs acting as cellular rheostats have the ability to modulate gene expression. In higher eukaryotes, microRNAs may regulate as much as 50 p

Biological Knowledge Discovery Handbook

Author : Mourad Elloumi
Publisher : John Wiley & Sons
ISBN 13 : 1118617118
Total Pages : 1192 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Biological Knowledge Discovery Handbook by : Mourad Elloumi

Download or read book Biological Knowledge Discovery Handbook written by Mourad Elloumi and published by John Wiley & Sons. This book was released on 2013-12-24 with total page 1192 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first comprehensive overview of preprocessing, mining,and postprocessing of biological data Molecular biology is undergoing exponential growth in both thevolume and complexity of biological data—and knowledgediscovery offers the capacity to automate complex search and dataanalysis tasks. This book presents a vast overview of the mostrecent developments on techniques and approaches in the field ofbiological knowledge discovery and data mining (KDD)—providingin-depth fundamental and technical field information on the mostimportant topics encountered. Written by top experts, Biological Knowledge DiscoveryHandbook: Preprocessing, Mining, and Postprocessing of BiologicalData covers the three main phases of knowledge discovery (datapreprocessing, data processing—also known as datamining—and data postprocessing) and analyzes both verificationsystems and discovery systems. BIOLOGICAL DATA PREPROCESSING Part A: Biological Data Management Part B: Biological Data Modeling Part C: Biological Feature Extraction Part D Biological Feature Selection BIOLOGICAL DATA MINING Part E: Regression Analysis of Biological Data Part F Biological Data Clustering Part G: Biological Data Classification Part H: Association Rules Learning from Biological Data Part I: Text Mining and Application to Biological Data Part J: High-Performance Computing for Biological DataMining Combining sound theory with practical applications in molecularbiology, Biological Knowledge Discovery Handbook is idealfor courses in bioinformatics and biological KDD as well as forpractitioners and professional researchers in computer science,life science, and mathematics.

Applied Ontology

Author : Katherine Munn
Publisher : Walter de Gruyter
ISBN 13 : 3110324865
Total Pages : 342 pages
Book Rating : 4.1/5 (13 download)

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Book Synopsis Applied Ontology by : Katherine Munn

Download or read book Applied Ontology written by Katherine Munn and published by Walter de Gruyter. This book was released on 2013-05-02 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ontology is the philosophical discipline which aims to understand how things in the world are divided into categories and how these categories are related together. This is exactly what information scientists aim for in creating structured, automated representations, called ‘ontologies,’ for managing information in fields such as science, government, industry, and healthcare. Currently, these systems are designed in a variety of different ways, so they cannot share data with one another. They are often idiosyncratically structured, accessible only to those who created them, and unable to serve as inputs for automated reasoning. This volume shows, in a non-technical way and using examples from medicine and biology, how the rigorous application of theories and insights from philosophical ontology can improve the ontologies upon which information management depends.

Encyclopedia of Bioinformatics and Computational Biology

Author :
Publisher : Elsevier
ISBN 13 : 0128114320
Total Pages : 3421 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Encyclopedia of Bioinformatics and Computational Biology by :

Download or read book Encyclopedia of Bioinformatics and Computational Biology written by and published by Elsevier. This book was released on 2018-08-21 with total page 3421 pages. Available in PDF, EPUB and Kindle. Book excerpt: Encyclopedia of Bioinformatics and Computational Biology: ABC of Bioinformatics, Three Volume Set combines elements of computer science, information technology, mathematics, statistics and biotechnology, providing the methodology and in silico solutions to mine biological data and processes. The book covers Theory, Topics and Applications, with a special focus on Integrative –omics and Systems Biology. The theoretical, methodological underpinnings of BCB, including phylogeny are covered, as are more current areas of focus, such as translational bioinformatics, cheminformatics, and environmental informatics. Finally, Applications provide guidance for commonly asked questions. This major reference work spans basic and cutting-edge methodologies authored by leaders in the field, providing an invaluable resource for students, scientists, professionals in research institutes, and a broad swath of researchers in biotechnology and the biomedical and pharmaceutical industries. Brings together information from computer science, information technology, mathematics, statistics and biotechnology Written and reviewed by leading experts in the field, providing a unique and authoritative resource Focuses on the main theoretical and methodological concepts before expanding on specific topics and applications Includes interactive images, multimedia tools and crosslinking to further resources and databases

Handbook of Statistical Genetics

Author : David J. Balding
Publisher : John Wiley & Sons
ISBN 13 : 9780470997628
Total Pages : 1616 pages
Book Rating : 4.9/5 (976 download)

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Book Synopsis Handbook of Statistical Genetics by : David J. Balding

Download or read book Handbook of Statistical Genetics written by David J. Balding and published by John Wiley & Sons. This book was released on 2008-06-10 with total page 1616 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook for Statistical Genetics is widely regarded as the reference work in the field. However, the field has developed considerably over the past three years. In particular the modeling of genetic networks has advanced considerably via the evolution of microarray analysis. As a consequence the 3rd edition of the handbook contains a much expanded section on Network Modeling, including 5 new chapters covering metabolic networks, graphical modeling and inference and simulation of pedigrees and genealogies. Other chapters new to the 3rd edition include Human Population Genetics, Genome-wide Association Studies, Family-based Association Studies, Pharmacogenetics, Epigenetics, Ethic and Insurance. As with the second Edition, the Handbook includes a glossary of terms, acronyms and abbreviations, and features extensive cross-referencing between the chapters, tying the different areas together. With heavy use of up-to-date examples, real-life case studies and references to web-based resources, this continues to be must-have reference in a vital area of research. Edited by the leading international authorities in the field. David Balding - Department of Epidemiology & Public Health, Imperial College An advisor for our Probability & Statistics series, Professor Balding is also a previous Wiley author, having written Weight-of-Evidence for Forensic DNA Profiles, as well as having edited the two previous editions of HSG. With over 20 years teaching experience, he’s also had dozens of articles published in numerous international journals. Martin Bishop – Head of the Bioinformatics Division at the HGMP Resource Centre As well as the first two editions of HSG, Dr Bishop has edited a number of introductory books on the application of informatics to molecular biology and genetics. He is the Associate Editor of the journal Bioinformatics and Managing Editor of Briefings in Bioinformatics. Chris Cannings – Division of Genomic Medicine, University of Sheffield With over 40 years teaching in the area, Professor Cannings has published over 100 papers and is on the editorial board of many related journals. Co-editor of the two previous editions of HSG, he also authored a book on this topic.

Handbook of Research on Advancements of Swarm Intelligence Algorithms for Solving Real-World Problems

Author : Cheng, Shi
Publisher : IGI Global
ISBN 13 : 1799832244
Total Pages : 482 pages
Book Rating : 4.7/5 (998 download)

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Book Synopsis Handbook of Research on Advancements of Swarm Intelligence Algorithms for Solving Real-World Problems by : Cheng, Shi

Download or read book Handbook of Research on Advancements of Swarm Intelligence Algorithms for Solving Real-World Problems written by Cheng, Shi and published by IGI Global. This book was released on 2020-04-24 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of optimization algorithms has seen an emergence in various professional fields due to its ability to process data and information in an efficient and productive manner. Combining computational intelligence with these algorithms has created a trending subject of research on how much more beneficial intelligent-inspired algorithms can be within companies and organizations. As modern theories and applications are continually being developed in this area, professionals are in need of current research on how intelligent algorithms are advancing in the real world. TheHandbook of Research on Advancements of Swarm Intelligence Algorithms for Solving Real-World Problems is a pivotal reference source that provides vital research on the development of swarm intelligence algorithms and their implementation into current issues. While highlighting topics such as multi-agent systems, bio-inspired computing, and evolutionary programming, this publication explores various concepts and theories of swarm intelligence and outlines future directions of development. This book is ideally designed for IT specialists, researchers, academicians, engineers, developers, practitioners, and students seeking current research on the real-world applications of intelligent algorithms.

Ontology-Based Information Retrieval for Healthcare Systems

Author : Vishal Jain
Publisher : John Wiley & Sons
ISBN 13 : 1119641381
Total Pages : 384 pages
Book Rating : 4.1/5 (196 download)

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Book Synopsis Ontology-Based Information Retrieval for Healthcare Systems by : Vishal Jain

Download or read book Ontology-Based Information Retrieval for Healthcare Systems written by Vishal Jain and published by John Wiley & Sons. This book was released on 2020-07-29 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the advancements of semantic web, ontology has become the crucial mechanism for representing concepts in various domains. For research and dispersal of customized healthcare services, a major challenge is to efficiently retrieve and analyze individual patient data from a large volume of heterogeneous data over a long time span. This requirement demands effective ontology-based information retrieval approaches for clinical information systems so that the pertinent information can be mined from large amount of distributed data. This unique and groundbreaking book highlights the key advances in ontology-based information retrieval techniques being applied in the healthcare domain and covers the following areas: Semantic data integration in e-health care systems Keyword-based medical information retrieval Ontology-based query retrieval support for e-health implementation Ontologies as a database management system technology for medical information retrieval Information integration using contextual knowledge and ontology merging Collaborative ontology-based information indexing and retrieval in health informatics An ontology-based text mining framework for vulnerability assessment in health and social care An ontology-based multi-agent system for matchmaking patient healthcare monitoring A multi-agent system for querying heterogeneous data sources with ontologies for reducing cost of customized healthcare systems A methodology for ontology based multi agent systems development Ontology based systems for clinical systems: validity, ethics and regulation

An Introduction to Ontology Engineering

Author : C. Maria Keet
Publisher :
ISBN 13 : 9781848902954
Total Pages : 344 pages
Book Rating : 4.9/5 (29 download)

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Book Synopsis An Introduction to Ontology Engineering by : C. Maria Keet

Download or read book An Introduction to Ontology Engineering written by C. Maria Keet and published by . This book was released on 2018-11-07 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: An Introduction to Ontology Engineering introduces the student to a comprehensive overview of ontology engineering, and offers hands-on experience that illustrate the theory. The topics covered include: logic foundations for ontologies with languages and automated reasoning, developing good ontologies with methods and methodologies, the top-down approach with foundational ontologies, and the bottomup approach to extract content from legacy material, and a selection of advanced topics that includes Ontology-Based Data Access, the interaction between ontologies and natural languages, and advanced modelling with fuzzy and temporal ontologies. Each chapter contains review questions and exercises, and descriptions of two group assignments are provided as well. The textbook is aimed at advanced undergraduate/postgraduate level in computer science and could fi t a semester course in ontology engineering or a 2-week intensive course. Domain experts and philosophers may fi nd a subset of the chapters of interest, or work through the chapters in a different order. Maria Keet is an Associate Professor with the Department of Computer Science, University of Cape Town, South Africa. She received her PhD in Computer Science in 2008 at the KRDB Research Centre, Free University of Bozen-Bolzano, Italy. Her research focus is on knowledge engineering with ontologies and Ontology, and their interaction with natural language and conceptual data modelling, which has resulted in over 100 peer-reviewed publications. She has developed and taught multiple courses on ontology engineering and related courses at various universities since 2009.

Handbook of Statistical Genomics

Author : David J. Balding
Publisher : John Wiley & Sons
ISBN 13 : 1119429250
Total Pages : 1740 pages
Book Rating : 4.1/5 (194 download)

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Book Synopsis Handbook of Statistical Genomics by : David J. Balding

Download or read book Handbook of Statistical Genomics written by David J. Balding and published by John Wiley & Sons. This book was released on 2019-07-09 with total page 1740 pages. Available in PDF, EPUB and Kindle. Book excerpt: A timely update of a highly popular handbook on statistical genomics This new, two-volume edition of a classic text provides a thorough introduction to statistical genomics, a vital resource for advanced graduate students, early-career researchers and new entrants to the field. It introduces new and updated information on developments that have occurred since the 3rd edition. Widely regarded as the reference work in the field, it features new chapters focusing on statistical aspects of data generated by new sequencing technologies, including sequence-based functional assays. It expands on previous coverage of the many processes between genotype and phenotype, including gene expression and epigenetics, as well as metabolomics. It also examines population genetics and evolutionary models and inference, with new chapters on the multi-species coalescent, admixture and ancient DNA, as well as genetic association studies including causal analyses and variant interpretation. The Handbook of Statistical Genomics focuses on explaining the main ideas, analysis methods and algorithms, citing key recent and historic literature for further details and references. It also includes a glossary of terms, acronyms and abbreviations, and features extensive cross-referencing between chapters, tying the different areas together. With heavy use of up-to-date examples and references to web-based resources, this continues to be a must-have reference in a vital area of research. Provides much-needed, timely coverage of new developments in this expanding area of study Numerous, brand new chapters, for example covering bacterial genomics, microbiome and metagenomics Detailed coverage of application areas, with chapters on plant breeding, conservation and forensic genetics Extensive coverage of human genetic epidemiology, including ethical aspects Edited by one of the leading experts in the field along with rising stars as his co-editors Chapter authors are world-renowned experts in the field, and newly emerging leaders. The Handbook of Statistical Genomics is an excellent introductory text for advanced graduate students and early-career researchers involved in statistical genetics.

Mass Spectrometry Handbook

Author : Mike S. Lee
Publisher : John Wiley & Sons
ISBN 13 : 1118180720
Total Pages : 1362 pages
Book Rating : 4.1/5 (181 download)

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Book Synopsis Mass Spectrometry Handbook by : Mike S. Lee

Download or read book Mass Spectrometry Handbook written by Mike S. Lee and published by John Wiley & Sons. This book was released on 2012-04-16 with total page 1362 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to its enormous sensitivity and ease of use, mass spectrometry has grown into the analytical tool of choice in most industries and areas of research. This unique reference provides an extensive library of methods used in mass spectrometry, covering applications of mass spectrometry in fields as diverse as drug discovery, environmental science, forensic science, clinical analysis, polymers, oil composition, doping, cellular research, semiconductor, ceramics, metals and alloys, and homeland security. The book provides the reader with a protocol for the technique described (including sampling methods) and explains why to use a particular method and not others. Essential for MS specialists working in industrial, environmental, and clinical fields.

The Text Mining Handbook

Author : Ronen Feldman
Publisher : Cambridge University Press
ISBN 13 : 0521836573
Total Pages : 423 pages
Book Rating : 4.5/5 (218 download)

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Book Synopsis The Text Mining Handbook by : Ronen Feldman

Download or read book The Text Mining Handbook written by Ronen Feldman and published by Cambridge University Press. This book was released on 2007 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: Publisher description

The Cambridge Handbook of Linguistic Anthropology

Author : N. J. Enfield
Publisher : Cambridge University Press
ISBN 13 : 1139992325
Total Pages : 910 pages
Book Rating : 4.1/5 (399 download)

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Book Synopsis The Cambridge Handbook of Linguistic Anthropology by : N. J. Enfield

Download or read book The Cambridge Handbook of Linguistic Anthropology written by N. J. Enfield and published by Cambridge University Press. This book was released on 2014-09-11 with total page 910 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of linguistic anthropology looks at human uniqueness and diversity through the lens of language, our species' special combination of art and instinct. Human language both shapes, and is shaped by, our minds, societies, and cultural worlds. This state-of-the-field survey covers a wide range of topics, approaches and theories, such as the nature and function of language systems, the relationship between language and social interaction, and the place of language in the social life of communities. Promoting a broad vision of the subject, spanning a range of disciplines from linguistics to biology, from psychology to sociology and philosophy, this authoritative handbook is an essential reference guide for students and researchers working on language and culture across the social sciences.

Handbook on Ontologies

Author : Steffen Staab
Publisher : Springer Science & Business Media
ISBN 13 : 3540247505
Total Pages : 661 pages
Book Rating : 4.5/5 (42 download)

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Book Synopsis Handbook on Ontologies by : Steffen Staab

Download or read book Handbook on Ontologies written by Steffen Staab and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 661 pages. Available in PDF, EPUB and Kindle. Book excerpt: An ontology is a description (like a formal specification of a program) of concepts and relationships that can exist for an agent or a community of agents. The concept is important for the purpose of enabling knowledge sharing and reuse. The Handbook on Ontologies provides a comprehensive overview of the current status and future prospectives of the field of ontologies. The handbook demonstrates standards that have been created recently, it surveys methods that have been developed and it shows how to bring both into practice of ontology infrastructures and applications that are the best of their kind.

The Oncogenomics Handbook

Author : William J. LaRochelle
Publisher : Springer Science & Business Media
ISBN 13 : 1592598935
Total Pages : 745 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis The Oncogenomics Handbook by : William J. LaRochelle

Download or read book The Oncogenomics Handbook written by William J. LaRochelle and published by Springer Science & Business Media. This book was released on 2007-11-09 with total page 745 pages. Available in PDF, EPUB and Kindle. Book excerpt: An integrated overview of cancer drug discovery and development from the bench to the clinic, showing with broad strokes and representative examples the drug development process as a network of linked components leading from the discovered target to the ultimate therapeutic product. Following a systems biology approach, the authors explain genomic databases and how to discover oncological targets from them, how then to advance from the gene and transcript to the level of protein biochemistry, how next to move from the chemical realm to that of the living cell and, ultimately, pursue animal modeling and clinical development. Emerging cancer therapeutics including Ritux an, Erbitux, Gleevec Herceptin, Avastin, ABX-EGF, Velcade, Kepivance, Iressa, Tarceva, and Zevalin are addressed. Highlights include cancer genomics, pharmacogenomics, transcriptomics, gene expression analysis, proteomic and enzymatic cancer profiling technologies, and cellular and animal approaches to cancer target validation.