The Gene Ontology Handbook

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The Gene Ontology Handbook

Author : Christophe Dessimoz
Publisher :
ISBN 13 : 9781013267703
Total Pages : 298 pages
Book Rating : 4.2/5 (677 download)

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Book Synopsis The Gene Ontology Handbook by : Christophe Dessimoz

Download or read book The Gene Ontology Handbook written by Christophe Dessimoz and published by . This book was released on 2020-10-08 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a practical and self-contained overview of the Gene Ontology (GO), the leading project to organize biological knowledge on genes and their products across genomic resources. Written for biologists and bioinformaticians, it covers the state-of-the-art of how GO annotations are made, how they are evaluated, and what sort of analyses can and cannot be done with the GO. In the spirit of the Methods in Molecular Biology book series, there is an emphasis throughout the chapters on providing practical guidance and troubleshooting advice. Authoritative and accessible, The Gene Ontology Handbook serves non-experts as well as seasoned GO users as a thorough guide to this powerful knowledge system. This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors.

The Gene Ontology Handbook

Author : Christophe Dessimoz
Publisher :
ISBN 13 : 9781013267710
Total Pages : 298 pages
Book Rating : 4.2/5 (677 download)

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Book Synopsis The Gene Ontology Handbook by : Christophe Dessimoz

Gene Ontology: A Resource for Analysis and Interpretation of Biological Database

Author : Paige Hill
Publisher :
ISBN 13 : 9781647403805
Total Pages : 0 pages
Book Rating : 4.4/5 (38 download)

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Book Synopsis Gene Ontology: A Resource for Analysis and Interpretation of Biological Database by : Paige Hill

Download or read book Gene Ontology: A Resource for Analysis and Interpretation of Biological Database written by Paige Hill and published by . This book was released on 2023-09-26 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The gene ontology (GO) is a bioinformatics project which aims to merge the representation of gene and characteristics of gene product in all species. It is a thorough and updated compilation of biological information that is utilized as a resource for computational representation of the most recent scientific data available concerning coding as well as non-coding functions of genes. High-throughput biological datasets can be interpreted and analyzed using the GO resource. The goal of the GO analysis is to pinpoint the molecular functions, biological processes and cellular locations of the genes. It utilizes markup language in order to make the genetic data and curated attributes of gene products readable by machine, in a manner which is integrated across all species. This book provides comprehensive insights on gene ontology. It aims to shed light on some of the unexplored aspects of this subject. Those in search of information to further their knowledge will be greatly assisted by this book.

Biological Knowledge Discovery Handbook

Author : Mourad Elloumi
Publisher : John Wiley & Sons
ISBN 13 : 1118853725
Total Pages : 1192 pages
Book Rating : 4.1/5 (188 download)

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Book Synopsis Biological Knowledge Discovery Handbook by : Mourad Elloumi

Download or read book Biological Knowledge Discovery Handbook written by Mourad Elloumi and published by John Wiley & Sons. This book was released on 2015-02-04 with total page 1192 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first comprehensive overview of preprocessing, mining,and postprocessing of biological data Molecular biology is undergoing exponential growth in both thevolume and complexity of biological data—and knowledgediscovery offers the capacity to automate complex search and dataanalysis tasks. This book presents a vast overview of the mostrecent developments on techniques and approaches in the field ofbiological knowledge discovery and data mining (KDD)—providingin-depth fundamental and technical field information on the mostimportant topics encountered. Written by top experts, Biological Knowledge DiscoveryHandbook: Preprocessing, Mining, and Postprocessing of BiologicalData covers the three main phases of knowledge discovery (datapreprocessing, data processing—also known as datamining—and data postprocessing) and analyzes both verificationsystems and discovery systems. BIOLOGICAL DATA PREPROCESSING Part A: Biological Data Management Part B: Biological Data Modeling Part C: Biological Feature Extraction Part D Biological Feature Selection BIOLOGICAL DATA MINING Part E: Regression Analysis of Biological Data Part F Biological Data Clustering Part G: Biological Data Classification Part H: Association Rules Learning from Biological Data Part I: Text Mining and Application to Biological Data Part J: High-Performance Computing for Biological DataMining Combining sound theory with practical applications in molecularbiology, Biological Knowledge Discovery Handbook is idealfor courses in bioinformatics and biological KDD as well as forpractitioners and professional researchers in computer science,life science, and mathematics.

Regulation of Gene Expression by Small RNAs

Author : Rajesh K. Gaur
Publisher : CRC Press
ISBN 13 : 1420008706
Total Pages : 440 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Regulation of Gene Expression by Small RNAs by : Rajesh K. Gaur

Download or read book Regulation of Gene Expression by Small RNAs written by Rajesh K. Gaur and published by CRC Press. This book was released on 2009-04-27 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: New Findings Revolutionize Concepts of Gene FunctionEndogenous small RNAs have been found in various organisms, including humans, mice, flies, worms, fungi, and bacteria. Furthermore, it's been shown that microRNAs acting as cellular rheostats have the ability to modulate gene expression. In higher eukaryotes, microRNAs may regulate as much as 50 p

Handbook Of Metadata, Semantics And Ontologies

Author : Sicilia Miguel-angel
Publisher : World Scientific
ISBN 13 : 9814590355
Total Pages : 580 pages
Book Rating : 4.8/5 (145 download)

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Book Synopsis Handbook Of Metadata, Semantics And Ontologies by : Sicilia Miguel-angel

Download or read book Handbook Of Metadata, Semantics And Ontologies written by Sicilia Miguel-angel and published by World Scientific. This book was released on 2013-12-17 with total page 580 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metadata research has emerged as a discipline cross-cutting many domains, focused on the provision of distributed descriptions (often called annotations) to Web resources or applications. Such associated descriptions are supposed to serve as a foundation for advanced services in many application areas, including search and location, personalization, federation of repositories and automated delivery of information. Indeed, the Semantic Web is in itself a concrete technological framework for ontology-based metadata. For example, Web-based social networking requires metadata describing people and their interrelations, and large databases with biological information use complex and detailed metadata schemas for more precise and informed search strategies.There is a wide diversity in the languages and idioms used for providing meta-descriptions, from simple structured text in metadata schemas to formal annotations using ontologies, and the technologies for storing, sharing and exploiting meta-descriptions are also diverse and evolve rapidly. In addition, there is a proliferation of schemas and standards related to metadata, resulting in a complex and moving technological landscape — hence, the need for specialized knowledge and skills in this area.The Handbook of Metadata, Semantics and Ontologies is intended as an authoritative reference for students, practitioners and researchers, serving as a roadmap for the variety of metadata schemas and ontologies available in a number of key domain areas, including culture, biology, education, healthcare, engineering and library science.

Encyclopedia of Bioinformatics and Computational Biology

Author :
Publisher : Elsevier
ISBN 13 : 0128114320
Total Pages : 3421 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Encyclopedia of Bioinformatics and Computational Biology by :

Download or read book Encyclopedia of Bioinformatics and Computational Biology written by and published by Elsevier. This book was released on 2018-08-21 with total page 3421 pages. Available in PDF, EPUB and Kindle. Book excerpt: Encyclopedia of Bioinformatics and Computational Biology: ABC of Bioinformatics, Three Volume Set combines elements of computer science, information technology, mathematics, statistics and biotechnology, providing the methodology and in silico solutions to mine biological data and processes. The book covers Theory, Topics and Applications, with a special focus on Integrative –omics and Systems Biology. The theoretical, methodological underpinnings of BCB, including phylogeny are covered, as are more current areas of focus, such as translational bioinformatics, cheminformatics, and environmental informatics. Finally, Applications provide guidance for commonly asked questions. This major reference work spans basic and cutting-edge methodologies authored by leaders in the field, providing an invaluable resource for students, scientists, professionals in research institutes, and a broad swath of researchers in biotechnology and the biomedical and pharmaceutical industries. Brings together information from computer science, information technology, mathematics, statistics and biotechnology Written and reviewed by leading experts in the field, providing a unique and authoritative resource Focuses on the main theoretical and methodological concepts before expanding on specific topics and applications Includes interactive images, multimedia tools and crosslinking to further resources and databases

Applied Ontology

Author : Katherine Munn
Publisher : Walter de Gruyter
ISBN 13 : 3110324865
Total Pages : 342 pages
Book Rating : 4.1/5 (13 download)

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Book Synopsis Applied Ontology by : Katherine Munn

Download or read book Applied Ontology written by Katherine Munn and published by Walter de Gruyter. This book was released on 2013-05-02 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ontology is the philosophical discipline which aims to understand how things in the world are divided into categories and how these categories are related together. This is exactly what information scientists aim for in creating structured, automated representations, called ‘ontologies,’ for managing information in fields such as science, government, industry, and healthcare. Currently, these systems are designed in a variety of different ways, so they cannot share data with one another. They are often idiosyncratically structured, accessible only to those who created them, and unable to serve as inputs for automated reasoning. This volume shows, in a non-technical way and using examples from medicine and biology, how the rigorous application of theories and insights from philosophical ontology can improve the ontologies upon which information management depends.

The Handbook of Genetics & Society

Author : Paul Atkinson
Publisher : Routledge
ISBN 13 : 1134128770
Total Pages : 566 pages
Book Rating : 4.1/5 (341 download)

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Book Synopsis The Handbook of Genetics & Society by : Paul Atkinson

Download or read book The Handbook of Genetics & Society written by Paul Atkinson and published by Routledge. This book was released on 2009-07-02 with total page 566 pages. Available in PDF, EPUB and Kindle. Book excerpt: An authoritative Handbook which offers a discussion of the social, political, ethical and economic consequences and implications of the new bio-sciences. The Handbook takes an interdisciplinary approach providing a synoptic overview of contemporary international social science research on genetics, genomics and the new life sciences. It brings together leading scholars with expertise across a wide-ranging spectrum of research fields related to the production, use, commercialisation and regulation of genetics knowledge. The Handbook is structured into seven cross-cutting themes in contemporary social science research on genetics with introductions written by internationally renowned section editors who take an interdisciplinary approach to offer fresh insights on recent developments and issues in often controversial fields of study. The Handbook explores local and global issues and critically approaches a wide range of public and policy questions, providing an invaluable reference source to a wide variety of researchers, academics and policy makers.

The Semantic Web – ISWC 2005

Author : Yolanda Gil
Publisher : Springer Science & Business Media
ISBN 13 : 3540297545
Total Pages : 1095 pages
Book Rating : 4.5/5 (42 download)

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Book Synopsis The Semantic Web – ISWC 2005 by : Yolanda Gil

Download or read book The Semantic Web – ISWC 2005 written by Yolanda Gil and published by Springer Science & Business Media. This book was released on 2005-11-04 with total page 1095 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the 4th International Semantic Web Conference, ISWC 2005, held in Galway, Ireland, in November 2005. The 54 revised full academic papers and 17 revised industrial papers presented together with abstracts of 3 invited talks were carefully reviewed and selected from a total of 217 submitted papers to the academic track and 30 to the industrial track. The research papers address all current issues in the field of the semantic Web, ranging from theoretical aspects to various applications. The industrial track contains papers on applications in particular industrical sectors, new technology for building applications, and methodological and feasibility aspects of building industrical applications that incorporate semantic Web technology. Short descriptions of the top five winning applications submitted to the Semantic Web Challenge competition conclude the volume.

The Text Mining Handbook

Author : Ronen Feldman
Publisher : Cambridge University Press
ISBN 13 : 0521836573
Total Pages : 423 pages
Book Rating : 4.5/5 (218 download)

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Book Synopsis The Text Mining Handbook by : Ronen Feldman

Download or read book The Text Mining Handbook written by Ronen Feldman and published by Cambridge University Press. This book was released on 2007 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: Publisher description

Handbook on Ontologies

Author : Steffen Staab
Publisher : Springer Science & Business Media
ISBN 13 : 3540247505
Total Pages : 661 pages
Book Rating : 4.5/5 (42 download)

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Book Synopsis Handbook on Ontologies by : Steffen Staab

Download or read book Handbook on Ontologies written by Steffen Staab and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 661 pages. Available in PDF, EPUB and Kindle. Book excerpt: An ontology is a description (like a formal specification of a program) of concepts and relationships that can exist for an agent or a community of agents. The concept is important for the purpose of enabling knowledge sharing and reuse. The Handbook on Ontologies provides a comprehensive overview of the current status and future prospectives of the field of ontologies. The handbook demonstrates standards that have been created recently, it surveys methods that have been developed and it shows how to bring both into practice of ontology infrastructures and applications that are the best of their kind.

Handbook of Semantic Web Technologies

Author : John Domingue
Publisher : Springer Science & Business Media
ISBN 13 : 3540929126
Total Pages : 1077 pages
Book Rating : 4.5/5 (49 download)

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Book Synopsis Handbook of Semantic Web Technologies by : John Domingue

Download or read book Handbook of Semantic Web Technologies written by John Domingue and published by Springer Science & Business Media. This book was released on 2011-06-19 with total page 1077 pages. Available in PDF, EPUB and Kindle. Book excerpt: After years of mostly theoretical research, Semantic Web Technologies are now reaching out into application areas like bioinformatics, eCommerce, eGovernment, or Social Webs. Applications like genomic ontologies, semantic web services, automated catalogue alignment, ontology matching, or blogs and social networks are constantly increasing, often driven or at least backed up by companies like Google, Amazon, YouTube, Facebook, LinkedIn and others. The need to leverage the potential of combining information in a meaningful way in order to be able to benefit from the Web will create further demand for and interest in Semantic Web research. This movement, based on the growing maturity of related research results, necessitates a reliable reference source from which beginners to the field can draw a first basic knowledge of the main underlying technologies as well as state-of-the-art application areas. This handbook, put together by three leading authorities in the field, and supported by an advisory board of highly reputed researchers, fulfils exactly this need. It is the first dedicated reference work in this field, collecting contributions about both the technical foundations of the Semantic Web as well as their main usage in other scientific fields like life sciences, engineering, business, or education.

Handbook of Toxicogenomics

Author : Jürgen Borlak
Publisher : John Wiley & Sons
ISBN 13 : 3527604510
Total Pages : 705 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Handbook of Toxicogenomics by : Jürgen Borlak

Download or read book Handbook of Toxicogenomics written by Jürgen Borlak and published by John Wiley & Sons. This book was released on 2006-03-06 with total page 705 pages. Available in PDF, EPUB and Kindle. Book excerpt: Toxicogenomics is a new, dynamic and very promising field that can help optimize toxicity analyses and streamline research into active substances. It is of interest not only for basic research and development, but also from a legal and ethical perspective. Here, experts from all the fields mentioned will find solid information provided by an international team of experienced authors. With its approach as an interdisciplinary overview, it will prove particularly useful for all those needing to develop appropriate research strategies. The authors work for major research institutions, such as the Fraunhofer Institute of Toxicology and Experimental Medicine (Germany), the German Cancer Research Center, the National Institute of Environmental Health Science (USA), the National Institute of Health Science (Japan) or for companies like Affymetrix, Altana Pharma, Bayer, Boehringer Ingelheim, Bruker, Merck, Nimblegen, Novartis, and Syngenta. Coverage ranges from the technology platforms applied, including DNA arrays or proteomics, via the bioinformatics tools required, right up to applications of toxicogenomics presented in numerous case studies, while also including an overview of national programs and initiatives as well as regulatory perspectives. Walter Rosenthal, Director of the Research Institute for Molecular Pharmacology in Berlin, praises the book thus: "I would like to congratulate the publishers of this handbook, one that deals with a extremely hot topic. They have succeeded in gaining as authors leading representatives from this field. The Handbook impressively shows how modern genomic research is leading to rapid advances and new insights within toxicology."

Prediction of Protein Structures, Functions, and Interactions

Author : Janusz M. Bujnicki
Publisher : John Wiley & Sons
ISBN 13 : 9780470741900
Total Pages : 302 pages
Book Rating : 4.7/5 (419 download)

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Book Synopsis Prediction of Protein Structures, Functions, and Interactions by : Janusz M. Bujnicki

Download or read book Prediction of Protein Structures, Functions, and Interactions written by Janusz M. Bujnicki and published by John Wiley & Sons. This book was released on 2008-12-23 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: The growing flood of new experimental data generated by genome sequencing has provided an impetus for the development of automated methods for predicting the functions of proteins that have been deduced by sequence analysis and lack experimental characterization. Prediction of Protein Structures, Functions and Interactions presents a comprehensive overview of methods for prediction of protein structure or function, with the emphasis on their availability and possibilities for their combined use. Methods of modeling of individual proteins, prediction of their interactions, and docking of complexes are put in the context of predicting gene ontology (biological process, molecular function, and cellular component) and discussed in the light of their contribution to the emerging field of systems biology. Topics covered include: first steps of protein sequence analysis and structure prediction automated prediction of protein function from sequence template-based prediction of three-dimensional protein structures: fold-recognition and comparative modelling template-free prediction of three-dimensional protein structures quality assessment of protein models prediction of molecular interactions: from small ligands to large protein complexes macromolecular docking integrating prediction of structure, function, and interactions Prediction of Protein Structures, Functions and Interactions focuses on the methods that have performed well in CASPs, and which are constantly developed and maintained, and are freely available to academic researchers either as web servers or programs for local installation. It is an essential guide to the newest, best methods for prediction of protein structure and functions, for researchers and advanced students working in structural bioinformatics, protein chemistry, structural biology and drug discovery.

Principles of Data Integration

Author : AnHai Doan
Publisher : Elsevier
ISBN 13 : 0123914795
Total Pages : 522 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Principles of Data Integration by : AnHai Doan

Download or read book Principles of Data Integration written by AnHai Doan and published by Elsevier. This book was released on 2012-06-25 with total page 522 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Data Integration is the first comprehensive textbook of data integration, covering theoretical principles and implementation issues as well as current challenges raised by the semantic web and cloud computing. The book offers a range of data integration solutions enabling you to focus on what is most relevant to the problem at hand. Readers will also learn how to build their own algorithms and implement their own data integration application. Written by three of the most respected experts in the field, this book provides an extensive introduction to the theory and concepts underlying today's data integration techniques, with detailed, instruction for their application using concrete examples throughout to explain the concepts. This text is an ideal resource for database practitioners in industry, including data warehouse engineers, database system designers, data architects/enterprise architects, database researchers, statisticians, and data analysts; students in data analytics and knowledge discovery; and other data professionals working at the R&D and implementation levels. Offers a range of data integration solutions enabling you to focus on what is most relevant to the problem at hand Enables you to build your own algorithms and implement your own data integration applications

The Handbook of Medicinal Chemistry

Author : Simon E Ward
Publisher : Royal Society of Chemistry
ISBN 13 : 183916588X
Total Pages : 1051 pages
Book Rating : 4.8/5 (391 download)

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Book Synopsis The Handbook of Medicinal Chemistry by : Simon E Ward

Download or read book The Handbook of Medicinal Chemistry written by Simon E Ward and published by Royal Society of Chemistry. This book was released on 2023-02-03 with total page 1051 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely revised and updated, the 2nd edition of The Handbook of Medicinal Chemistry draws together contributions from authoritative practitioners to provide a comprehensive overview of the field as well as insight into the latest trends and research. An ideal companion for students in medicinal chemistry, drug discovery and drug development, while also communicating core principles, the book places the discipline within the context of the burgeoning platform of new modalities now available to drug discovery. The book also highlights the role chemistry has to play in wider target validation and translational technologies. This is a carefully curated compilation of writing from global experts using their broad experience of medicinal chemistry, project leadership and drug discovery and development from an industry, academic and charity perspective to provide unparalleled insight into the field.