The Function And Modulation Of Programmed Cell Death 4 Pdcd4 In Ovarian Cancer

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Translation and Its Regulation in Cancer Biology and Medicine

Author : Armen Parsyan
Publisher : Springer
ISBN 13 : 9401790787
Total Pages : 709 pages
Book Rating : 4.4/5 (17 download)

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Book Synopsis Translation and Its Regulation in Cancer Biology and Medicine by : Armen Parsyan

Download or read book Translation and Its Regulation in Cancer Biology and Medicine written by Armen Parsyan and published by Springer. This book was released on 2014-10-13 with total page 709 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, for the first time, comprehensively assembles and analyzes a large body of information on the role of the fundamental mechanism of the protein biosynthesis pathway, translation, in cancer biology. It systematically explores the function of the translation machinery and its regulation, including cell signaling, in the development, maintenance and progression of human cancer. The work presented here unveils the tremendous potential and applications of this vast and exciting branch of genetic, biochemical and molecular science in cancer medicine and drug development. Chapters contributed by experts in the field take the reader on a journey that starts with a dissection of the translation machinery and its regulation in norm and cancer. Later chapters characterize etiological and pathogenetic roles that translation plays in specific cancer types. Various aspects of diagnostic, prognostic and therapeutic significance of the translation machinery and its control in cancer are discussed. Readers will discover the importance of the process of translation and its regulatory mechanisms in physiology and cancer biology. The chapters and the numerous illustrations included here were contributed by expert scientists and clinicians from renowned academic and clinical establishments in Canada, the United States of America, the United Kingdom, Italy, France, Belgium, Spain, Germany and Australia. The book conveys information and knowledge that may interest a broad range of students and scholars ranging from basic scientists to clinicians and drug developers seeking to better understand the protein synthesis and its aberrations in cancer biology and cancer medicine.

Targeting the Microenvironment Niche in Hematologic Malignancies

Author : Cirino Botta
Publisher : Frontiers Media SA
ISBN 13 : 2889742679
Total Pages : 193 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Targeting the Microenvironment Niche in Hematologic Malignancies by : Cirino Botta

Download or read book Targeting the Microenvironment Niche in Hematologic Malignancies written by Cirino Botta and published by Frontiers Media SA. This book was released on 2022-02-02 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Genomic alteration landscapes of aging, metabolic disorders, and cancer: emerging overlaps and clinical importance

Author : Rajkumar S. Kalra
Publisher : Frontiers Media SA
ISBN 13 : 2832513832
Total Pages : 172 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Genomic alteration landscapes of aging, metabolic disorders, and cancer: emerging overlaps and clinical importance by : Rajkumar S. Kalra

Download or read book Genomic alteration landscapes of aging, metabolic disorders, and cancer: emerging overlaps and clinical importance written by Rajkumar S. Kalra and published by Frontiers Media SA. This book was released on 2023-02-07 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Human and Oncoviral Noncoding RNAs as Modulators of Cancer Aggressiveness and Disease Progression

Author : Deilson Elgui De Oliveira
Publisher : Frontiers Media SA
ISBN 13 : 2889665658
Total Pages : 185 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Human and Oncoviral Noncoding RNAs as Modulators of Cancer Aggressiveness and Disease Progression by : Deilson Elgui De Oliveira

Download or read book Human and Oncoviral Noncoding RNAs as Modulators of Cancer Aggressiveness and Disease Progression written by Deilson Elgui De Oliveira and published by Frontiers Media SA. This book was released on 2021-03-05 with total page 185 pages. Available in PDF, EPUB and Kindle. Book excerpt:

MicroRNAs in Cancer

Author : Cesar Lopez-Camarillo
Publisher : CRC Press
ISBN 13 : 1466576774
Total Pages : 426 pages
Book Rating : 4.4/5 (665 download)

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Book Synopsis MicroRNAs in Cancer by : Cesar Lopez-Camarillo

Download or read book MicroRNAs in Cancer written by Cesar Lopez-Camarillo and published by CRC Press. This book was released on 2013-02-22 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: MicroRNA (miRNA) biology is a cutting-edge topic in basic as well as biomedical research. This is a specialized book focusing on the current understanding of the role of miRNAs in the development, progression, invasion, and metastasis of diverse types of cancer. It also reviews their potential for applications in cancer diagnosis, prognosis, and th

From “Junk DNA” to Clinically Relevant Tools for Cancer Diagnosis, Staging, and Tailored Therapies: The Incredible Case of Non-Coding RNAs

Download From “Junk DNA” to Clinically Relevant Tools for Cancer Diagnosis, Staging, and Tailored Therapies: The Incredible Case of Non-Coding RNAs PDF Online Free

Author : Marilena V. Iorio
Publisher : Frontiers Media SA
ISBN 13 : 2889459659
Total Pages : 113 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis From “Junk DNA” to Clinically Relevant Tools for Cancer Diagnosis, Staging, and Tailored Therapies: The Incredible Case of Non-Coding RNAs by : Marilena V. Iorio

Download or read book From “Junk DNA” to Clinically Relevant Tools for Cancer Diagnosis, Staging, and Tailored Therapies: The Incredible Case of Non-Coding RNAs written by Marilena V. Iorio and published by Frontiers Media SA. This book was released on 2019-08-22 with total page 113 pages. Available in PDF, EPUB and Kindle. Book excerpt:

MicroRNAs in Medicine

Author : Charles H. Lawrie
Publisher : John Wiley & Sons
ISBN 13 : 1118300343
Total Pages : 702 pages
Book Rating : 4.1/5 (183 download)

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Book Synopsis MicroRNAs in Medicine by : Charles H. Lawrie

Download or read book MicroRNAs in Medicine written by Charles H. Lawrie and published by John Wiley & Sons. This book was released on 2013-10-30 with total page 702 pages. Available in PDF, EPUB and Kindle. Book excerpt: MicroRNAs in Medicine provides an access point into the current literature on microRNA for both scientists and clinicians, with an up-to-date look at what is happening in the emerging field of microRNAs and their relevance to medicine. Each chapter is a comprehensive review, with descriptions of the latest microRNA research written by international leaders in their field. Opening with an introduction to what microRNAs are and how they function, the book goes on to explore the role of microRNAs in normal physiological functions, infectious diseases, non-infectious diseases, cancer, circulating microRNAs as non-invasive biomarkers, and finally their potential as novel therapeutics. Including background information on the field as well as reviews of the latest research breakthroughs, MicroRNAs in Medicine is a one-stop source of information to satisfy the specialists and non-specialists alike, appealing to students, researchers, and clinicians interested in understanding the potential of microRNAs in medicine and research.

Hormonal Signaling in Biology and Medicine

Author : Gerald Litwack
Publisher : Academic Press
ISBN 13 : 0128138157
Total Pages : 740 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Hormonal Signaling in Biology and Medicine by : Gerald Litwack

Download or read book Hormonal Signaling in Biology and Medicine written by Gerald Litwack and published by Academic Press. This book was released on 2019-10-24 with total page 740 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hormonal Signaling in Biology and Medicine: Comprehensive Modern Endocrinology covers the endocrine secretions produced by every organ. This extensive collection of knowledge is organized by tissue, addressing how certain hormones are synthesized in multiple tissues, along with their structure, function and pathways, which are very applicable for researchers in drug design who need to focus on a specific step along the pathway. This is a must have reference for researchers in endocrinology and practicing endocrinologists, but it is also ideal for biochemists, pharmacologists, biologists and students. - Serves as a valuable desk reference for researchers - Provides information on the structure of a given hormone, its receptor(s), and the pathways that become activated - Includes extensive citations to the literature that will enable the reader to dig more deeply into the effects of a given hormone

Mechanisms of Carcinogenesis

Author : Elizabeth K. Weisburger
Publisher : Springer Science & Business Media
ISBN 13 : 9400925263
Total Pages : 210 pages
Book Rating : 4.4/5 (9 download)

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Book Synopsis Mechanisms of Carcinogenesis by : Elizabeth K. Weisburger

Download or read book Mechanisms of Carcinogenesis written by Elizabeth K. Weisburger and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: but also the possibility of intervention in specific stages. In Human behavior, including stress and other factors, plays an important role in neoplasia, although too little is known addition, variables which affect cancer development as well on the reasons for such development. Carcinogens, which as some endogenous factors can be better delineated help initiate the neoplastic process, may be either synthetic through such investigations. The topics of this volume encompass premalignant non or naturally-occurring. Cancer causation may be ascribed to invasive lesions, species-specific aspects of carcinogenicity, certain chemicals, physical agents, radioactive materials, viruses, parasites, the genetic make-up of the organism, and radiation, viruses, a quantum theory of carinogenesis, onco bacteria. Humans, eumetazoan animals and vascular plants genes, and selected environmental carcinogens. are susceptible to the first six groups of cancer causes, whe reas the last group, bacteria, seems to affect only vascular plants. Neoplastic development may begin with impairment ofJmdy defenses by a toxic material (carcinogen) which acts as an initiator, followed by promotion and progression to an overt neoplastic state. Investigation of these processes Series Editor Volume Editor allows not only a better insight into the mechanism of action Hans E. Kaiser Elizabeth K. Weisburger vii ACKNOWLEDGEMENT Inspiration and encouragement for this wide ranging project on cancer distribution and dissemination from a comparative biological and clinical point of view, was given by my late friend E. H. Krokowski.

Cancer Research

Author :
Publisher :
ISBN 13 :
Total Pages : 1268 pages
Book Rating : 4.E/5 ( download)

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Book Synopsis Cancer Research by :

Download or read book Cancer Research written by and published by . This book was released on 2005-12 with total page 1268 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Role of Nutraceuticals in Cancer Chemosensitization

Author :
Publisher : Academic Press
ISBN 13 : 0128123745
Total Pages : 400 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Role of Nutraceuticals in Cancer Chemosensitization by :

Download or read book Role of Nutraceuticals in Cancer Chemosensitization written by and published by Academic Press. This book was released on 2017-10-18 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Role of Nutraceuticals in Chemoresistance to Cancer, Volume Two, focuses on nutraceuticals, the compounds derived from natural sources, which are usually multi-targeted as a means to overcome chemoresistance. This book discusses the role of several compounds related to nutraceuticals and chemoresistance, such as curcumin, resveratrol, indole 3-carbinol, tocotrienols, ursolic acid, fisetin, celastrol, gambogic, butein, catechins and silymarin. It is a valuable resource for cancer researchers, oncologists and members of several areas of the biomedical field who are interested in understanding how to use nutraceuticals as a sensitizing agent for chemotherapy. - Brings updated information on natural compounds used as specific inhibitors of cell signaling pathways as reviewed by experts in the field - Presents experts analysis and summary of reported and novel findings and potential translational application in cancer patients - Describes molecular mechanisms with new and helpful approaches for the readers to use in their own investigations

Systems Biology of Cancer

Author : Sam Thiagalingam
Publisher : Cambridge University Press
ISBN 13 : 0521493390
Total Pages : 597 pages
Book Rating : 4.5/5 (214 download)

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Book Synopsis Systems Biology of Cancer by : Sam Thiagalingam

Download or read book Systems Biology of Cancer written by Sam Thiagalingam and published by Cambridge University Press. This book was released on 2015-04-09 with total page 597 pages. Available in PDF, EPUB and Kindle. Book excerpt: An overview of the current systems biology-based knowledge and the experimental approaches for deciphering the biological basis of cancer.

Index Medicus

Author :
Publisher :
ISBN 13 :
Total Pages : 1876 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Index Medicus by :

Download or read book Index Medicus written by and published by . This book was released on 2004 with total page 1876 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.

Multi-Drug Resistance in Cancer

Author : Jun Zhou
Publisher : Humana Press
ISBN 13 : 9781617796647
Total Pages : 492 pages
Book Rating : 4.7/5 (966 download)

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Book Synopsis Multi-Drug Resistance in Cancer by : Jun Zhou

Download or read book Multi-Drug Resistance in Cancer written by Jun Zhou and published by Humana Press. This book was released on 2012-08-09 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemotherapy is one of the major treatment options for cancer patients; however, the efficacy of chemotherapeutic management of cancer is severely limited by multidrug resistance, in that cancer cells become simultaneously resistant to many structurally and mechanistically unrelated drugs. In the past three decades, a number of mechanisms by which cancer cells acquire multidrug resistance have been discovered. In addition, the development of agents or strategies to overcome resistance has been the subject of intense study. This book contains comprehensive and up-to-date reviews of multidrug resistance mechanisms, from over-expression of ATP-binding cassette drug transporters such as P-glycoprotein, multidrug resistance-associated proteins, and breast cancer resistance p- tein to the drug ratio-dependent antagonism and the paradigm of cancer stem cells. The book also includes strategies to overcome multidrug resistance, from the development of compounds that inhibit drug transporter function to the modulation of transporter expression. In addition, this book contains techniques for the detection and imaging of drug transporters, methods for the investigation of drug resistance in animal models, and strategies to evaluate the efficacy of resistance reversal agents. The book intends to provide a state-of-the-art collection of reviews and methods for both basic and clinician investigators who are interested in cancer multidrug resistance mechanisms and reversal strategies. Tianjin, China Jun Zhou v Contents Preface. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . v Contributors. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ix 1 Multidrug Resistance in Cancer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 Bruce C. Baguley 2 Multidrug Resistance in Oncology and Beyond: From Imaging of Drug Efflux Pumps to Cellular Drug Targets . . . . . . . . . . . . . . . . . . . . . . . . . .

Wound Healing

Author : Kursad Turksen
Publisher : John Wiley & Sons
ISBN 13 : 1119282489
Total Pages : 320 pages
Book Rating : 4.1/5 (192 download)

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Book Synopsis Wound Healing by : Kursad Turksen

Download or read book Wound Healing written by Kursad Turksen and published by John Wiley & Sons. This book was released on 2018-02-21 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive resource on the recent developments of stem cell use in wound healing With contributions from experts in the field, Wound Healing offers a thorough review of the most recent findings on the use of stem cells to heal wounds. This important resource covers both the basic and translational aspects of the field. The contributors reveal the great progress that has been made in recent years and explore a wide range of topics from an overview of the stem cell process in wound repair to inflammation and cancer. They offer a better understanding of the identities of skin stem cells as well as the signals that govern their behavior that contributes to the development of improved therapies for scarring and poorly healing wounds. Comprehensive in scope, this authoritative resource covers a wealth of topics such as: an overview of stem cell regeneration and repair, wound healing and cutaneous wound healing, the role of bone marrow derived stems cells, inflammation in wound repair, role and function of inflammation in wound repair, and much more. This vital resource: Provides a comprehensive overview of stem cell use in wound healing, including both the basic and translational aspects of the field Covers recent developments and emerging subtopics within the field Offers an invaluable resource to clinical and basic researchers who are interested in wound healing, stem cells, and regenerative medicine Contains contributions from leading experts in the field of wound healing and care Wound Healing offers clinical researchers and academics a much-needed resource written by noted experts in the field that explores the role of stem cells in the repair and restoration of healing wounds.

Membrane Biogenesis

Author : Jos A.F. Op den Kamp
Publisher : Springer Science & Business Media
ISBN 13 : 3642731848
Total Pages : 474 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis Membrane Biogenesis by : Jos A.F. Op den Kamp

Download or read book Membrane Biogenesis written by Jos A.F. Op den Kamp and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many individual aspects of the dynamics and assembly of biological membranes have been studied in great detail. Cell biological approaches, advanced genetics, biophysics and biochemistry have greatly contributed to an increase in our knowledge in this field.lt is obvious however, that the three major membrane constituents - lipids, proteins and carbohydrates- are studied, in most cases separately and that a coherent overview of the various aspects of membrane biogenesis is not readily available. The NATO Advanced Study Institute on "New Perspectives in the Dynamics of Assembly of Biomembranes" intended to provide such an overview: it was set up to teach students and specialists the achievements obtained in the various research areas and to try and integrate the numerous aspects of membrane assembly into a coherent framework. The articles in here reflect this. Statting with detailed contributions on phospholipid structure, dynamics, organization and biogenesis, an up to date overview of the basic, lipidic backbone of biomembranes is given. Extensive progress is made in the research on membrane protein biosynthesis. In particular the post- and co-translational modification processes of proteins, the mechanisms of protein translocation and the sorting mechanisms which are necessary to direct proteins to their final, intra - or extracellular destination have been characterized in detail. Modern genetic approaches were indispensable in this research area: gene cloning, hybrid protein construction, site directed mutagenesis and sequencing techniques elucidated many functional aspects of specific nucleic acid and amino acid sequences.

Alcohol and Cancer

Author : Vasilis Vasiliou
Publisher : Springer
ISBN 13 : 3319987887
Total Pages : 274 pages
Book Rating : 4.3/5 (199 download)

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Book Synopsis Alcohol and Cancer by : Vasilis Vasiliou

Download or read book Alcohol and Cancer written by Vasilis Vasiliou and published by Springer. This book was released on 2018-10-26 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: Following the Third Alcohol and Cancer Conference, this volume compiles the most up-to-date research on the role of alcohol consumption in carcinogenesis, from epidemiology to pathology metabolism and stem cells. More specifically, it delves into the effects of alcohol consumption and thyroid cancer, CD133+ progenitor cells, carcinogenic iron accumulation, developmental morphogens, and cancer-inducing epigenetic changes. Alcohol and Cancer: Proceedings of the Third International Conference is a timely update to Biological Basis of Alcohol-Induced Cancer, which followed the Second Alcohol and Cancer Conference, compiling cutting-edge research from graduate students, young scientists, and researchers. It is ideal for graduate students and researchers in oncology, hepatology, epigenetics, and alcohol consumption.