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The Effects Of Moderate And High Intensity Exercise On Vascular Endothelial Function In Normal Weight And Obese Adults
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Book Synopsis The Effects of Moderate- and High- Intensity Exercise on Vascular Endothelial Function in Normal Weight and Obese Adults by : Rachel Hallmark
Download or read book The Effects of Moderate- and High- Intensity Exercise on Vascular Endothelial Function in Normal Weight and Obese Adults written by Rachel Hallmark and published by . This book was released on 2008 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Effects of High-fat Diet and Exercise on Vascular Endothelial Function by :
Download or read book The Effects of High-fat Diet and Exercise on Vascular Endothelial Function written by and published by . This book was released on 2008 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Comparison of High-intensity Interval Exercise Vs. Continuous Moderate Exercise on C1Q/TNF-related Protein-9 Expression and Flow-mediated Vasodilation in Obese Individuals by : Brandon G. Fico
Download or read book The Comparison of High-intensity Interval Exercise Vs. Continuous Moderate Exercise on C1Q/TNF-related Protein-9 Expression and Flow-mediated Vasodilation in Obese Individuals written by Brandon G. Fico and published by . This book was released on 2017 with total page 50 pages. Available in PDF, EPUB and Kindle. Book excerpt: The primary purpose of this study was to investigate the effect of acute high-intensity interval exercise (HIIE) vs. continuous moderate-intensity exercise (CME) on serum CTRP9 and brachial FMD responses in obese and normal-weight subjects. Sixteen participants (9 obese and 7 normal-weight) completed HIIE and CME in a randomized fashion. Our results showed a significant time effect for CTRP9 immediately following acute HIIE and CME in both groups. Furthermore, both significant treatment by time and group by time interactions for FMD were observed following both exercise protocols, with greater CME-induced FMD response in obese subjects than normal-weight subjects. Additionally, a positive correlation in percent change (baseline to peak) between CTRP9 and FMD was observed following acute CME. These findings support acute CME for improvement of endothelial function in obesity. Furthermore, the novel results from this study provide a foundation for additional examination of the mechanisms of exercise-mediated CTRP9 on endothelial function.
Book Synopsis Endothelium and Cardiovascular Diseases by : Protasio L. Da Luz
Download or read book Endothelium and Cardiovascular Diseases written by Protasio L. Da Luz and published by Academic Press. This book was released on 2018-02-03 with total page 760 pages. Available in PDF, EPUB and Kindle. Book excerpt: Endothelium and Cardiovascular Diseases: Vascular Biology and Clinical Syndromes provides an in-depth examination of the role of endothelium and endothelial dysfunction in normal vascular function, and in a broad spectrum of clinical syndromes, from atherosclerosis, to cognitive disturbances and eclampsia. The endothelium is a major participant in the pathophysiology of diseases, such as atherosclerosis, diabetes and hypertension, and these entities are responsible for the largest part of cardiovascular mortality and morbidly. Over the last decade major new discoveries and concepts involving the endothelium have come to light. This important reference collects this data in an easy to reference resource. Written by known experts, and covering all aspects of endothelial function in health and disease, this reference represents an assembly of recent knowledge that is essential to both basic investigators and clinicians. Provides a complete overview of endothelial function in health and diseases, along with an assessment of new information Includes coverage of groundbreaking areas, including the artificial LDL particle, the development of a new anti-erectile dysfunction agent, a vaccine for atherosclerosis, coronary calcification associated with red wine, and the interplay of endoplasmic reticulum/oxidative stress Explores the genetic features of endothelium and the interaction between basic knowledge and clinical syndromes
Book Synopsis Exercise and Diabetes by : Sheri R. Colberg
Download or read book Exercise and Diabetes written by Sheri R. Colberg and published by American Diabetes Association. This book was released on 2013-05-30 with total page 554 pages. Available in PDF, EPUB and Kindle. Book excerpt: Physical movement has a positive effect on physical fitness, morbidity, and mortality in individuals with diabetes. Although exercise has long been considered a cornerstone of diabetes management, many health care providers fail to prescribe it. In addition, many fitness professionals may be unaware of the complexities of including physical activity in the management of diabetes. Giving patients or clients a full exercise prescription that take other chronic conditions commonly accompanying diabetes into account may be too time-consuming for or beyond the expertise of many health care and fitness professionals. The purpose of this book is to cover the recommended types and quantities of physical activities that can and should be undertaken by all individuals with any type of diabetes, along with precautions related to medication use and diabetes-related health complications. Medications used to control diabetes should augment lifestyle improvements like increased daily physical activity rather than replace them. Up until now, professional books with exercise information and prescriptions were not timely or interactive enough to easily provide busy professionals with access to the latest recommendations for each unique patient. However, simply instructing patients to “exercise more” is frequently not motivating or informative enough to get them regularly or safely active. This book is changing all that with its up-to-date and easy-to-prescribe exercise and physical activity recommendations and relevant case studies. Read and learn to quickly prescribe effective and appropriate exercise to everyone.
Book Synopsis Effects of Eight Weeks of High-intensity Interval Training on Blood Glucose Control, Endothelial Function, and Visceral Fat in Obese Adults by : Brandon J. Sawyer
Download or read book Effects of Eight Weeks of High-intensity Interval Training on Blood Glucose Control, Endothelial Function, and Visceral Fat in Obese Adults written by Brandon J. Sawyer and published by . This book was released on 2013 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiovascular disease (CVD) is the number one cause of death in the United States and type 2 diabetes (T2D) and obesity lead to cardiovascular disease. Obese adults are more susceptible to CVD compared to their non-obese counterparts. Exercise training leads to large reductions in the risk of CVD and T2D. Recent evidence suggests high-intensity interval training (HIT) may yield similar or superior benefits in a shorter amount of time compared to traditional continuous exercise training. The purpose of this study was to compare the effects of HIT to continuous (CONT) exercise training for the improvement of endothelial function, glucose control, and visceral adipose tissue. Seventeen obese men (N=9) and women (N=8) were randomized to eight weeks of either HIT (N=9, age=34 years, BMI=37.6 kg/m2) or CONT (N=8, age=34 years, BMI=34.6 kg/m2) exercise 3 days/week for 8 weeks. Endothelial function was assessed via flow-mediated dilation (FMD), glucose control was assessed via continuous glucose monitoring (CGM), and visceral adipose tissue and body composition was measured with an iDXA. Incremental exercise testing was performed at baseline, 4 weeks, and 8 weeks. There were no changes in weight, fat mass, or visceral adipose tissue measured by the iDXA, but there was a significant reduction in body fat that did not differ by group (46±6.3 to 45.4±6.6%, P=0.025). HIT led to a significantly greater improvement in FMD compared to CONT exercise (HIT: 5.1 to 9.0%; CONT: 5.0 to 2.6%, P=0.006). Average 24-hour glucose was not improved over the whole group and there were no group x time interactions for CGM data (HIT: 103.9 to 98.2 mg/dl; CONT: 99.9 to 100.2 mg/dl, P>0.05). When statistical analysis included only the subjects who started with an average glucose at baseline> 100 mg/dl, there was a significant improvement in glucose control overall, but no group x time interaction (107.8 to 94.2 mg/dl, P=0.027). Eight weeks of HIT led to superior improvements in endothelial function and similar improvements in glucose control in obese subjects at risk for T2D and CVD. HIT was shown to have comparable or superior health benefits in this obese sample with a 36% lower total exercise time commitment.
Book Synopsis High-Intensity Exercise in Hypoxia - Beneficial Aspects and Potential Drawbacks by : Olivier Girard
Download or read book High-Intensity Exercise in Hypoxia - Beneficial Aspects and Potential Drawbacks written by Olivier Girard and published by Frontiers Media SA. This book was released on 2018-01-25 with total page 169 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past, ‘traditional’ moderate-intensity continuous training (60-75% peak heart rate) was the type of physical activity most frequently recommended for both athletes and clinical populations (cf. American College of Sports Medicine guidelines). However, growing evidence indicates that high-intensity interval training (80-100% peak heart rate) could actually be associated with larger cardiorespiratory fitness and metabolic function benefits and, thereby, physical performance gains for athletes. Similarly, recent data in obese and hypertensive individuals indicate that various mechanisms – further improvement in endothelial function, reductions in sympathetic neural activity, or in arterial stiffness – might be involved in the larger cardiovascular protective effects associated with training at high exercise intensities. Concerning hypoxic training, similar trends have been observed from ‘traditional’ prolonged altitude sojourns (‘Live High Train High’ or ‘Live High Train Low’), which result in increased hemoglobin mass and blood carrying capacity. Recent innovative ‘Live Low Train High’ methods (‘Resistance Training in Hypoxia’ or ‘Repeated Sprint Training in Hypoxia’) have resulted in peripheral adaptations, such as hypertrophy or delay in muscle fatigue. Other interventions inducing peripheral hypoxia, such as vascular occlusion during endurance/resistance training or remote ischemic preconditioning (i.e. succession of ischemia/reperfusion episodes), have been proposed as methods for improving subsequent exercise performance or altitude tolerance (e.g. reduced severity of acute-mountain sickness symptoms). Postulated mechanisms behind these metabolic, neuro-humoral, hemodynamics, and systemic adaptations include stimulation of nitric oxide synthase, increase in anti-oxidant enzymes, and down-regulation of pro-inflammatory cytokines, although the amount of evidence is not yet significant enough. Improved O2 delivery/utilization conferred by hypoxic training interventions might also be effective in preventing and treating cardiovascular diseases, as well as contributing to improve exercise tolerance and health status of patients. For example, in obese subjects, combining exercise with hypoxic exposure enhances the negative energy balance, which further reduces weight and improves cardio-metabolic health. In hypertensive patients, the larger lowering of blood pressure through the endothelial nitric oxide synthase pathway and the associated compensatory vasodilation is taken to reflect the superiority of exercising in hypoxia compared to normoxia. A hypoxic stimulus, in addition to exercise at high vs. moderate intensity, has the potential to further ameliorate various aspects of the vascular function, as observed in healthy populations. This may have clinical implications for the reduction of cardiovascular risks. Key open questions are therefore of interest for patients suffering from chronic vascular or cellular hypoxia (e.g. work-rest or ischemia/reperfusion intermittent pattern; exercise intensity; hypoxic severity and exposure duration; type of hypoxia (normobaric vs. hypobaric); health risks; magnitude and maintenance of the benefits). Outside any potential beneficial effects of exercising in O2-deprived environments, there may also be long-term adverse consequences of chronic intermittent severe hypoxia. Sleep apnea syndrome, for instance, leads to oxidative stress and the production of reactive oxygen species, and ultimately systemic inflammation. Postulated pathophysiological changes associated with intermittent hypoxic exposure include alteration in baroreflex activity, increase in pulmonary arterial pressure and hematocrit, changes in heart structure and function, and an alteration in endothelial-dependent vasodilation in cerebral and muscular arteries. There is a need to explore the combination of exercising in hypoxia and association of hypertension, developmental defects, neuro-pathological and neuro-cognitive deficits, enhanced susceptibility to oxidative injury, and possibly increased myocardial and cerebral infarction in individuals sensitive to hypoxic stress. The aim of this Research Topic is to shed more light on the transcriptional, vascular, hemodynamics, neuro-humoral, and systemic consequences of training at high intensities under various hypoxic conditions.
Book Synopsis Effects of Aerobic Exercise Training on Arterial Stiffness and Autonomic Function in Obese Adults At-risk of Cardiovascular Disease and Type 2 Diabetes by : Joshua McGee
Download or read book Effects of Aerobic Exercise Training on Arterial Stiffness and Autonomic Function in Obese Adults At-risk of Cardiovascular Disease and Type 2 Diabetes written by Joshua McGee and published by . This book was released on 2020 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: Obesity is a major risk factor for cardiovascular disease (CVD), CVD mortality, and type 2 diabetes. Arterial stiffness and autonomic dysfunction are independent predictors of CVD and type 2 diabetes. Moreover, African Americans (AA) have a disproportionate prevalence of elevated arterial stiffness compared to Caucasians. Obese individuals have a greater prevalence of diminished autonomic nervous system activity compared to lean individuals. Despite evidence of aerobic exercise training benefiting arterial stiffness and autonomic dysfunction in the general population, optimal intensity and volume for AAs and obese individuals remain unclear. The purpose of this dissertation was to determine whether high-intensity aerobic exercise training improved arterial stiffness and aortic compliance to a greater degree than moderate intensity in obese AAs (study 1), if clinically significant weight loss from a combined hypocaloric diet and aerobic exercise intervention increases heart rate variability (HRV) in obese adults and to evaluate the impact of aerobic exercise volume on HRV during weight maintenance (study 2). Arterial stiffness or aortic compliance did not improve in response to 24 weeks of moderate- or high-intensity, supervised aerobic exercise training at a volume consistent with public health guidelines. However, both groups significantly increased cardiorespiratory fitness compared to the control group. In addition, we observed an inverse relationship between changes in cardiorespiratory fitness and aortic compliance. The results from this study suggest AAs may require greater volumes of weekly aerobic exercise than recommended for the general population to improve arterial stiffness. The 10-week, combined intervention improved major HRV indices of parasympathetic activity. The changes in parasympathetic activity were inversely associated with fasting insulin concentrations. Both groups retained all HRV benefits over the 18-week maintenance phase. The results from this study suggest weight loss via energy restriction and exercise alter autonomic function, leading to improved sympathovagal balance in obese adults, also exercise volumes consistent with physical activity guidelines maintains improvements in autonomic function from weight loss. Collectively, the results of this dissertation provide valuable public health insight for health professionals prescribing aerobic exercise to improve predictors of CVD and type 2 diabetes, specifically arterial stiffness, aortic compliance, and autonomic dysfunction in at-risk, obese adults.
Book Synopsis Effects of Exercise on Hypertension by : Linda S. Pescatello
Download or read book Effects of Exercise on Hypertension written by Linda S. Pescatello and published by Springer. This book was released on 2015-07-08 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the first primer on the effects of exercise on human hypertension, Effects of Exercise on Hypertension: From Cells to Physiological Systems provides the state-of-the-art effects of exercise on the many possible mechanisms underlying essential hypertension in humans. The book contains chapters by distinguished experts on the effects of exercise on physiological systems known to be involved in hypertension development and maintenance as well as less well known aspects of hypertension such as 24-hour ambulatory blood pressure profile and oxidative stress. An emerging area, the effects of resistance exercise training on blood pressure is also covered. A unique aspect of the book is that it covers the effects of exercise mimetics on vascular cell adaptations in order to begin to elucidate some of the cellular mechanisms that may underlie blood pressure reductions with exercise training. Lastly, the book will end with a chapter on the interactive effects of genes and exercise on blood pressure. Chapters are grouped by physiological system or mechanism. The text begins with two overview chapters; one on the general effects of aerobic exercise training and the second on the general effects of resistance exercise training on blood pressure. Each chapter begins with a bulleted list of key points. Effects of Exercise on Hypertension: From Cells to Physiological Systems will be of great value to professional individuals in cardiovascular medicine, the cardiovascular sciences, allied health care professionals, and medical and graduate students in the cardiovascular sciences and medicine.
Book Synopsis Effects of a Fat-sugar Supplemented Diet, with and Without Exercise Training, on Endothelial Function, Blood Pressure, and Markers of Cardiovascular Risk by : Laurie Black
Download or read book Effects of a Fat-sugar Supplemented Diet, with and Without Exercise Training, on Endothelial Function, Blood Pressure, and Markers of Cardiovascular Risk written by Laurie Black and published by . This book was released on 2013 with total page 147 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Western Pattern diet has been characterized by having greater than 50 percent consumption coming from fat and sugar. This macronutrient allocation has been shown to have deleterious effects on endothelial function and metabolic markers of cardiovascular disease. Exercise has been shown to improve vascular reactivity and metabolic markers related to cardiovascular health. The objective of the study was to determine if exercise training can prevent the anticipated deleterious effects of a fat-sugar supplemented diet on endothelial function and blood markers of cardiovascular risk in young men. Twenty-one, healthy college-aged males were randomly assigned to either the doughnut + exercise or doughnut only groups. Both groups were fed 2 doughnuts per day, 6 days per week, for three weeks, while maintain their current diet. The exercise group completed 4 exercise training sessions per week consisting of 2 high intensity interval training bouts (up to 95% VO2peak) on a cycle ergometer and two moderate intensity, steady-state bouts (at 75% VO2peak) on a treadmill. Changes in body weight and composition, markers of endothelial function, oxidative stress, serum lipids, and blood glucose were measured in each group. As expected, cardiovascular fitness increased significantly in the doughnut-supplemented + exercise group as compared to the doughnut-supplemented (p=0.005). Significant increases in body weight (p=0.036), fat mass (p=0.013), and body fat percentage (p=0.014) were seen in the doughnut only group as compared to the doughnut + exercise group. The doughnut + exercise group showed significant improvements in fasting serum triglycerides (p=0.036), plasma insulin (p=0.039) and insulin sensitivity (HOMA; p=0.05) as compared to the doughnut only group. The doughnut + exercise group saw a significant improvement in nitric oxide availability whereas the doughnut only group experienced a significant decline (p=0.014). There were no significant changes in other markers. Despite the addition of a fat/sugar supplement of ~11,600 kcal over three weeks, 4 exercise sessions per week were sufficient to prevent a gain in body weight and fat mass, and also improve some measures of cardiometabolic risk. These results suggest that exercise may be necessary to prevent some adverse health outcomes associated with transient periods of excessive energy consumption.
Book Synopsis The Ketogenic Diet by : John Mark Freeman
Download or read book The Ketogenic Diet written by John Mark Freeman and published by Demos Medical Publishing. This book was released on 2000 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: This completely revised and updated third edition includes: new data from clinical studies and laboratory research that has expanded our knowledge about many aspects of the ketogenic diet; a clearer understanding of the best approaches to helping children and their families cope with the limitations and restrictions of the diet based on experience with hundreds of new patients; feedback and dialog from many sources, including neurologists, dietitians, and parents; new and improved menus, including some developed by professional chefs whose children were on the diet; and revised instructions for calculating and managing the diet on a day-to-day basis that reflect the needs of modern dietitians."--BOOK JACKET.
Book Synopsis Prevention and Management of Cardiovascular and Metabolic Disease by : Peter Kokkinos
Download or read book Prevention and Management of Cardiovascular and Metabolic Disease written by Peter Kokkinos and published by John Wiley & Sons. This book was released on 2023-04-24 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: Prevention and Management of Cardiovascular and Metabolic Disease Provides accurate and well-documented information on the impact of diet and physical activity in the prevention and management of cardiovascular and metabolic diseases and healthy aging. This authoritative textbook examines the independent and combined impact of diet and physical activity in the prevention and management of cardiovascular and metabolic diseases, with special emphasis on the elderly populations. In this book the authors: Provide the latest data on the association between a suboptimal diet and physical inactivity and chronic disease. Examine the role of epigenetics on longevity. Discuss the fundamentals of healthy aging. Highlight the role of well-known dietary patterns such as the Mediterranean diet and the Nordic diet in favorable health outcomes, including cardiovascular, metabolic health, and healthy aging. Discuss the health outcomes of physical activity and healthy aging. Present the most recent evidence-based data on the independent and synergistic impact of diet and exercise on disease prevention and management including, heart disease, diabetes mellitus, hypertension, dyslipidemia, kidney failure, cancer and other conditions. Prevention and Management of Cardiovascular and Metabolic Disease: Diet, Physical Activity and Healthy Aging is an excellent textbook for upper-level undergraduate and graduate students in medical and health-related disciplines and for health professionals, including dietitians and nutritionists, exercise physiologists, athletic trainers, nurses, physicians, geriatricians, and other health professionals with a special focus in older adults. This book is also a highly useful reference for health professionals interested in introducing diet and physical activity as an intervention for healthy aging as well as the prevention and management of cardiovascular and other metabolic diseases that are prevalent in aging populations.
Book Synopsis THE EFFECTS OF AGE ON ENDOTHELIAL RESPONSE TO HIGH INTENSITY INTERVAL TRAINING by : Gabe Gonzalez- Contreras
Download or read book THE EFFECTS OF AGE ON ENDOTHELIAL RESPONSE TO HIGH INTENSITY INTERVAL TRAINING written by Gabe Gonzalez- Contreras and published by . This book was released on 2023 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Purpose: The world population is growing exponentially older. The age-related loss of muscle mass and strength, termed sarcopenia, leads to loss of function and independence, disability, and increased mortality. Declining endothelial function during aging may increase dysfunction in muscle. Exercise may partly rescue muscle vascular function. High intensity interval training (HIIT) is a form of exercise that involves short bursts of intense exercise alternated with low intensity recovery periods. The main purpose of this study was to investigate the impact of age on endothelial response to HIIT. We also sought to determine the impact of HIIT on capillarization in both adult and older adult mice. Homogenized gastrocnemius C57BL/6 mice samples were used. The study randomly assigned C57BL/6 mice to a 13-week program of HIIT, with an additional sedentary control group. Randomized mice were adult ages (aged 6 months to 10 months) or older adult ages (aged 22 months to 26 months). Due to complications incurred during the SARS-CoV-2 epidemic, 28-months old mice served as the sedentary control group (28m). The functional ability of each mouse was measured pre- and post-training using our comprehensive functional assessment battery (CFAB) composite scoring system, consisting of five validated tests. Sarcopenia was measured through analyses of body composition (EchoMRI) and post-training muscle wet mass. Western immunoblots were performed using gastrocnemius homogenates to determine expression of vascular endothelial growth factor (VEGF), a potent angiogenic promoter, and immunohistochemistry was performed to determine the capillary to fiber ratio. We observed no statistically significant differences in VEGF expression with either age or exercise status compared to controls two days after the final training session, comparing means with a 1-Way ANOVA. However, due to large individual sample variation limiting power in the ANOVA, we used independent samples t-test, finding older mice had significantly less baseline VEGF expression, VEGF in older mice HIIT group tended to be elevated compared to controls, and HIIT restored VEGF levels to baseline levels of young adult mice. Immunohistochemistry results showed no statistical difference in capillarization between groups (HIIT, CON) in the older adult mice, albeit with a low n=3 per group. Results from the present study suggest that a HIIT training mode may not lead to chronically elevated VEGF levels within muscle in adults but may do so in older adults. This suggests that incorporating HIIT may enhance endothelial health in older adults. Future work is needed to determine if VEGF increased transiently after acute exercise bouts, and whether age plays a role in this response.
Book Synopsis Fitness Measures and Health Outcomes in Youth by : Institute of Medicine
Download or read book Fitness Measures and Health Outcomes in Youth written by Institute of Medicine and published by National Academies Press. This book was released on 2012-12-10 with total page 229 pages. Available in PDF, EPUB and Kindle. Book excerpt: Physical fitness affects our ability to function and be active. At poor levels, it is associated with such health outcomes as diabetes and cardiovascular disease. Physical fitness testing in American youth was established on a large scale in the 1950s with an early focus on performance-related fitness that gradually gave way to an emphasis on health-related fitness. Using appropriately selected measures to collected fitness data in youth will advance our understanding of how fitness among youth translates into better health. In Fitness Measures and Health Outcomes in Youth, the IOM assesses the relationship between youth fitness test items and health outcomes, recommends the best fitness test items, provides guidance for interpreting fitness scores, and provides an agenda for needed research. The report concludes that selected cardiorespiratory endurance, musculoskeletal fitness, and body composition measures should be in fitness surveys and in schools. Collecting fitness data nationally and in schools helps with setting and achieving fitness goals and priorities for public health at an individual and national level.
Book Synopsis The Effect of High-intensity Interval Exercise on Postprandial Endothelial Function in Youth by : Justin Ross Ryder
Download or read book The Effect of High-intensity Interval Exercise on Postprandial Endothelial Function in Youth written by Justin Ross Ryder and published by . This book was released on 2014 with total page 151 pages. Available in PDF, EPUB and Kindle. Book excerpt: In adults, consuming a high-fat meal can induce endothelial dysfunction while exercise may mitigate postprandial endothelial dysfunction. Whether exercise is protective against postprandial endothelial dysfunction in obese youth is unknown. The purpose of this study was to determine if high-intensity interval exercise (HIIE) performed the evening prior to a high-fat meal protects against postprandial endothelial dysfunction in obese adolescent males. Fourteen obese adolescent males (BMI%tile=98.5±0.6; 14.3±1.0yrs) completed the study. After initial screening, participants arrived, fasted at 9:00 in the morning where brachial artery flow-mediated dilation (FMD) was measured using duplex ultrasound after 20min of supine rest (7.0±3.0%) and completed a maximal exercise test on a cycle ergometer (VO2peak=2.6±0.5 L/min). Participants were randomized and completed 2 conditions: a morning high-fat meal challenge with evening prior HIIE (EX+M) or a morning high-fat meal challenge without prior exercise (MO). The EX+M condition included a single HIIE session on a cycle ergometer (8 X 2min at ≥90%HRmax, with 2min active recovery between bouts, 42min total) which was performed at 17:00 the evening prior to the meal challenge. In both conditions, a mixed-meal was tailored to participants body weight consisting of 0.7g of fat/kg of body weight consumed (889±95kcal; 65% Fat, 30% CHO). FMD was measured at fasting (>10hrs) and subsequently measured at 2hr and 4hr after high-fat meal consumption. Exercise did not improve fasting FMD (7.5±3.0 vs. 7.4±2.8%, P=0.927; EX+M and MO, respectively). Despite consuming a high-fat meal, FMD was not reduced at 2hr (8.4±3.4 vs. 7.6±3.9%; EX+M and MO, respectively) or 4hr (8.8±3.9 vs. 8.6±4.0%; EX+M and MO, respectively) in either condition and no differences were observed between condition (p(condition*time)=0.928). These observations remained after adjusting for baseline artery diameter and shear rate. We observed that HIIE, the evening prior, had no effect on fasting or postprandial endothelial function when compared with a meal only condition. Future research should examine whether exercise training may be able to improve postprandial endothelial function rather than a single acute bout in obese youth.
Book Synopsis Dissertation Abstracts International by :
Download or read book Dissertation Abstracts International written by and published by . This book was released on 2009-10 with total page 594 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Effects of Short-term High-intensity Interval, Moderate-intensity Continuous and Resistance Training on Cardiovascular Health in Older Adults by : Myles O'Brien
Download or read book The Effects of Short-term High-intensity Interval, Moderate-intensity Continuous and Resistance Training on Cardiovascular Health in Older Adults written by Myles O'Brien and published by . This book was released on 2018 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aging is associated with a decline in peripheral vascular endothelial function [i.e., flow-mediated dilation (FMD)] and cardiovagal baroreflex sensitivity (BRS), which are both critical to cardiovascular health. Accumulating evidence in younger adults suggest that high-intensity interval training (HIIT) provides superior benefits to cardiovascular health than moderate-intensity continuous training (MICT) and whole-body resistance training (RT). We tested whether 6-weeks of HIIT (n=6) improves upper- and lower-limb FMD and BRS more than MICT (n=9) and RT (n=8) in older adults (OA). FMD was assessed via high-resolution ultrasound. Cardiovagal BRS was assessed using Portapres® derived beat-by-beat systolic blood pressures and electrocardiogram-derived cardiac intervals via the 'spontaneous baroreflex sequence' method. Short-term HIIT and MICT elicited similar increases in BRS, brachial and popliteal FMD, whereas no changes were observed following RT. These results indicate that short-term aerobic training augments vascular health and blood pressure regulation more than RT in OA.
