The Effects Of Hypergravity And Microgravity On Biomedical Experiments

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The Effects of Hypergravity and Microgravity on Biomedical Experiments

Author : Thais Russomano
Publisher : Springer Nature
ISBN 13 : 3031016246
Total Pages : 70 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis The Effects of Hypergravity and Microgravity on Biomedical Experiments by : Thais Russomano

Download or read book The Effects of Hypergravity and Microgravity on Biomedical Experiments written by Thais Russomano and published by Springer Nature. This book was released on 2022-05-31 with total page 70 pages. Available in PDF, EPUB and Kindle. Book excerpt: Take one elephant and one man to the top of a tower and simultaneously drop. Which will hit the ground first? You are a pilot of a jet fighter performing a high-speed loop. Will you pass out during the maneuver? How can you simulate being an astronaut with your feet still firmly placed on planet Earth? In the aerospace environment, human, animal, and plant physiology differs significantly from that on Earth, and this book provides reasons for some of these changes. The challenges encountered by pilots in their missions can have implications on the health and safety of not only themselves but others. Knowing the effects of hypergravity on the human body during high-speed flight led to the development of human centrifuges. We also need to better understand the physiological responses of living organisms in space. It is therefore necessary to simulate weightlessness through the use of specially adapted equipment, such as clinostats, tilt tables, and body suspension devices. Each of these ideas, and more, is addressed in this review of the physical concepts related to space flights, microgravity, and hypergravity simulations. Basic theories, such as Newton’s law and Einstein’s principle are explained, followed by a look at the biomedical effects of experiments performed in space life sciences institutes, universities, and space agencies. Table of Contents: General Concepts in Physics - Definition of Physical Terms / The Effects of Hypergravity on Biomedical Experiments / The Effects of Microgravity on Biomedical Experiments / References

The Effects of Hypergravity and Microgravity on Biomedical Experiments

Author : Thais Russomano
Publisher : Morgan & Claypool Publishers
ISBN 13 : 1598295780
Total Pages : 77 pages
Book Rating : 4.5/5 (982 download)

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Book Synopsis The Effects of Hypergravity and Microgravity on Biomedical Experiments by : Thais Russomano

Download or read book The Effects of Hypergravity and Microgravity on Biomedical Experiments written by Thais Russomano and published by Morgan & Claypool Publishers. This book was released on 2008 with total page 77 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the aerospace environment, human, animal, and plant physiology differs significantly from that on Earth. This book provides a review of the physical concepts related to space flights, microgravity, and hypergravity simulations. Basic theories, such as Einstein's principle are explained, followed by a look at the biomedical effects of experiments performed in space life sciences institutes, universities, and space agencies.

The Effects Of Hypergravity And Microgravity On Biomedical Experiments

Author : Thais Russomano
Publisher :
ISBN 13 : 9781598295801
Total Pages : 70 pages
Book Rating : 4.2/5 (958 download)

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Book Synopsis The Effects Of Hypergravity And Microgravity On Biomedical Experiments by : Thais Russomano

Download or read book The Effects Of Hypergravity And Microgravity On Biomedical Experiments written by Thais Russomano and published by . This book was released on 2008 with total page 70 pages. Available in PDF, EPUB and Kindle. Book excerpt: Take one elephant and one man to the top of a tower and simultaneously drop. Which will hit the ground first? You are a pilot of a jet fighter performing a high-speed loop. Will you pass out during the maneuver? How can you simulate being an astronaut with your feet still firmly placed on planet Earth? In the aerospace environment, human, animal, and plant physiology differs significantly from that on Earth, and this book provides reasons for some of these changes. The challenges encountered by pilots in their missions can have implications on the health and safety of not only themselves but others. Knowing the effects of hypergravity on the human body during high-speed flight led to the development of human centrifuges. We also need to better understand the physiological responses of living organisms in space. It is therefore necessary to simulate weightlessness through the use of specially adapted equipment, such as clinostats, tilt tables, and body suspension devices. Each of these ideas, and more, is addressed in this review of the physical concepts related to space flights, microgravity, and hypergravity simulations. Basic theories, such as Newton's law and Einstein's principle are explained, followed by a look at the biomedical effects of experiments performed in space life sciences institutes, universities, and space agencies.

Biological and Medical Research in Space

Author : David Moore
Publisher : Springer Science & Business Media
ISBN 13 : 3642610994
Total Pages : 582 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis Biological and Medical Research in Space by : David Moore

Download or read book Biological and Medical Research in Space written by David Moore and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 582 pages. Available in PDF, EPUB and Kindle. Book excerpt: Life Science studies in space were initially driven by the need to explore how man could survive spaceflight conditions; the effects of being launched un der high accelerations, exposed to weightlessness and radiation for different periods of time, and returned to Earth in safety. In order to substantiate the detailed knowledge of potentially adverse effects, many model experiments were launched using organisms which ranged from bacteria, plants, inverte brates, rodents and primates through to man. Although no immediate life threatening effects were found, these experiments can be considered today as the precursors to life science research in space. Many unexplained effects on these life forms were attributed to the condition of weightlessness. Most of them were poorly recorded, poorly published, or left simply with anecdotal information. Only with the advent of Skylab, and later Spacelab, did the idea emerge, and indeed the infrastructure permit, weightlessness to be considered as an ex tended tool for research into some fundamental mechanisms or processes as sociated with the effect of gravity on organisms at all levels. The initial hy pothesis to extrapolate from hypergravity through 1 x g to near 0 x g effects could no longer be retained, since many of the experiment results were seen to contradict the models or theories in the current textbooks of biology and physiology. The past decade has been dedicated primarily to exploratory research.

Recapturing a Future for Space Exploration

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309163846
Total Pages : 464 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Recapturing a Future for Space Exploration by : National Research Council

Download or read book Recapturing a Future for Space Exploration written by National Research Council and published by National Academies Press. This book was released on 2012-01-30 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: More than four decades have passed since a human first set foot on the Moon. Great strides have been made in our understanding of what is required to support an enduring human presence in space, as evidenced by progressively more advanced orbiting human outposts, culminating in the current International Space Station (ISS). However, of the more than 500 humans who have so far ventured into space, most have gone only as far as near-Earth orbit, and none have traveled beyond the orbit of the Moon. Achieving humans' further progress into the solar system had proved far more difficult than imagined in the heady days of the Apollo missions, but the potential rewards remain substantial. During its more than 50-year history, NASA's success in human space exploration has depended on the agency's ability to effectively address a wide range of biomedical, engineering, physical science, and related obstacles-an achievement made possible by NASA's strong and productive commitments to life and physical sciences research for human space exploration, and by its use of human space exploration infrastructures for scientific discovery. The Committee for the Decadal Survey of Biological and Physical Sciences acknowledges the many achievements of NASA, which are all the more remarkable given budgetary challenges and changing directions within the agency. In the past decade, however, a consequence of those challenges has been a life and physical sciences research program that was dramatically reduced in both scale and scope, with the result that the agency is poorly positioned to take full advantage of the scientific opportunities offered by the now fully equipped and staffed ISS laboratory, or to effectively pursue the scientific research needed to support the development of advanced human exploration capabilities. Although its review has left it deeply concerned about the current state of NASA's life and physical sciences research, the Committee for the Decadal Survey on Biological and Physical Sciences in Space is nevertheless convinced that a focused science and engineering program can achieve successes that will bring the space community, the U.S. public, and policymakers to an understanding that we are ready for the next significant phase of human space exploration. The goal of this report is to lay out steps and develop a forward-looking portfolio of research that will provide the basis for recapturing the excitement and value of human spaceflight-thereby enabling the U.S. space program to deliver on new exploration initiatives that serve the nation, excite the public, and place the United States again at the forefront of space exploration for the global good.

Human Factors in Transportation

Author : Gesa Praetorius, Charlott Sellberg and Riccardo Patriarca
Publisher : AHFE International
ISBN 13 : 1958651710
Total Pages : 770 pages
Book Rating : 4.9/5 (586 download)

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Book Synopsis Human Factors in Transportation by : Gesa Praetorius, Charlott Sellberg and Riccardo Patriarca

Download or read book Human Factors in Transportation written by Gesa Praetorius, Charlott Sellberg and Riccardo Patriarca and published by AHFE International. This book was released on 2023-07-19 with total page 770 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of the 14th International Conference on Applied Human Factors and Ergonomics (AHFE 2023), July 20–24, 2023, San Francisco, USA

Introductory Medical Imaging

Author : Anil Bharath
Publisher : Springer Nature
ISBN 13 : 3031016319
Total Pages : 172 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Introductory Medical Imaging by : Anil Bharath

Download or read book Introductory Medical Imaging written by Anil Bharath and published by Springer Nature. This book was released on 2022-05-31 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an introduction to the principles of several of the more widely used methods in medical imaging. Intended for engineering students, it provides a final-year undergraduate- or graduate-level introduction to several imaging modalities, including MRI, ultrasound, and X-Ray CT. The emphasis of the text is on mathematical models for imaging and image reconstruction physics. Emphasis is also given to sources of imaging artefacts. Such topics are usually not addressed across the different imaging modalities in one book, and this is a notable strength of the treatment given here. Table of Contents: Introduction / Diagnostic X-Ray Imaging / X-Ray CT / Ultrasonics / Pulse-Echo Ultrasonic Imaging / Doppler Velocimetry / An Introduction to MRI

Models of Horizontal Eye Movements

Author : Alireza Ghahari
Publisher : Morgan & Claypool Publishers
ISBN 13 : 1627056599
Total Pages : 124 pages
Book Rating : 4.6/5 (27 download)

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Book Synopsis Models of Horizontal Eye Movements by : Alireza Ghahari

Download or read book Models of Horizontal Eye Movements written by Alireza Ghahari and published by Morgan & Claypool Publishers. This book was released on 2015-02-01 with total page 124 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are five different types of eye movements: saccades, smooth pursuit, vestibular ocular eye movements, optokinetic eye movements, and vergence eye movements. The purpose of this book series is focused primarily on mathematical models of the horizontal saccadic eye movement system and the smooth pursuit system, rather than on how visual information is processed. In Part 1, early models of saccades and smooth pursuit are presented. A number of oculomotor plant models are described here beginning with the Westheimer model published in 1954, and up through our 1995 model involving a 4th order oculomotor plant model. In Part 2, a 2009 version of a state-of-the-art model is presented for horizontal saccades that is 3rd-order and linear, and controlled by a physiologically based time-optimal neural network. Part 3 describes a model of the saccade system, focusing on the neural network. It presents a neural network model of biophysical neurons in the midbrain for controlling oculomotor muscles during horizontal human saccades. In this book, a multiscale model of the saccade system is presented, focusing on a multiscale neural network and muscle fiber model. Chapter 1 presents a comprehensive model for the control of horizontal saccades using a muscle fiber model for the lateral and medial rectus muscles. The importance of this model is that each muscle fiber has a separate neural input. This model is robust and accounts for the neural activity for both large and small saccades. The muscle fiber model consists of serial sequences of muscle fibers in parallel with other serial sequences of muscle fibers. Each muscle fiber is described by a parallel combination of a linear length tension element, viscous element, and active-state tension generator. Chapter 2 presents a biophysically realistic neural network model in the midbrain to drive a muscle fiber oculomotor plant during horizontal monkey saccades. Neural circuitry, including omnipause neuron, premotor excitatory and inhibitory burst neurons, long lead burst neuron, tonic neuron, interneuron, abducens nucleus, and oculomotor nucleus, is developed to examine saccade dynamics. The time-optimal control mechanism demonstrates how the neural commands are encoded in the downstream saccadic pathway by realization of agonist and antagonist controller models. Consequently, each agonist muscle fiber is stimulated by an agonist neuron, while an antagonist muscle fiber is unstimulated by a pause and step from the antagonist neuron. It is concluded that the neural network is constrained by a minimum duration of the agonist pulse, and that the most dominant factor in determining the saccade magnitude is the number of active neurons for the small saccades. For the large saccades, however, the duration of agonist burst firing significantly affects the control of saccades. The proposed saccadic circuitry establishes a complete model of saccade generation since it not only includes the neural circuits at both the premotor and motor stages of the saccade generator, but it also uses a time-optimal controller to yield the desired saccade magnitude.

Emerging Trends in Immunomodulatory Nanomaterials Toward Cancer Therapy

Author : Anubhab Mukherjee
Publisher : Springer Nature
ISBN 13 : 3031016696
Total Pages : 84 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Emerging Trends in Immunomodulatory Nanomaterials Toward Cancer Therapy by : Anubhab Mukherjee

Download or read book Emerging Trends in Immunomodulatory Nanomaterials Toward Cancer Therapy written by Anubhab Mukherjee and published by Springer Nature. This book was released on 2022-05-31 with total page 84 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recently, immunomodulatory nanomaterials have gained immense attention due to their involvement in the modulation of the body’s immune response to cancer therapy. This book highlights various immunomodulatory nanomaterials (including organic, polymer, inorganic, liposomes, viral, and protein nanoparticles) and their role in cancer therapy. Additionally, the mechanism of immunomodulation is reviewed in detail. Finally, the challenges of these therapies and their future outlook are discussed. We believe this book will be helpful to a broad community including students, researchers, educators, and industrialists.

Models of Horizontal Eye Movements, Part I

Author : John Enderle
Publisher : Springer Nature
ISBN 13 : 3031016424
Total Pages : 151 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Models of Horizontal Eye Movements, Part I by : John Enderle

Download or read book Models of Horizontal Eye Movements, Part I written by John Enderle and published by Springer Nature. This book was released on 2022-06-01 with total page 151 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are five different types of eye movements: saccades, smooth pursuit, vestibular ocular eye movements, optokinetic eye movements, and vergence eye movements. The purpose of this book is focused primarily on mathematical models of the horizontal saccadic eye movement system and the smooth pursuit system, rather than on how visual information is processed. A saccade is a fast eye movement used to acquire a target by placing the image of the target on the fovea. Smooth pursuit is a slow eye movement used to track a target as it moves by keeping the target on the fovea. The vestibular ocular movement is used to keep the eyes on a target during brief head movements. The optokinetic eye movement is a combination of saccadic and slow eye movements that keeps a full-field image stable on the retina during sustained head rotation. Each of these movements is a conjugate eye movement, that is, movements of both eyes together driven by a common neural source. A vergence movement is a non-conjugate eye movement allowing the eyes to track targets as they come closer or farther away. In this book, early models of saccades and smooth pursuit are presented. The smooth pursuit system allows tracking of a slow moving target to maintain its position on the fovea. Models of the smooth pursuit have been developed using systems control theory, all involving a negative feedback control system that includes a time delay, controller and plant in the forward loop, with unity feedback. The oculomotor plant and saccade generator are the basic elements of the saccadic system. The oculomotor plant consists of three muscle pairs and the eyeball. A number of oculomotor plant models are described here beginning with the Westheimer model published in 1954, and up through our 1995 model involving a 4$^{th}$ order oculomotor plant model. The work presented here is not an exhaustive coverage of the field, but focused on the interests of the author. In Part II, a state-of-art model of the saccade system is presented, including a neural network that controls the system. Table of Contents: Introduction / Smooth Pursuit Models / Early Models of the Horizontal Saccadic Eye Movement System / Velocity and Acceleration Estimation / 1995 Linear Homeomorphic Saccadic Eye Movement Model

Computerized Analysis of Mammographic Images for Detection and Characterization of Breast Cancer

Author : Arianna Mencattini
Publisher : Springer Nature
ISBN 13 : 3031016645
Total Pages : 166 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Computerized Analysis of Mammographic Images for Detection and Characterization of Breast Cancer by : Arianna Mencattini

Download or read book Computerized Analysis of Mammographic Images for Detection and Characterization of Breast Cancer written by Arianna Mencattini and published by Springer Nature. This book was released on 2022-05-31 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: The identification and interpretation of the signs of breast cancer in mammographic images from screening programs can be very difficult due to the subtle and diversified appearance of breast disease. This book presents new image processing and pattern recognition techniques for computer-aided detection and diagnosis of breast cancer in its various forms. The main goals are: (1) the identification of bilateral asymmetry as an early sign of breast disease which is not detectable by other existing approaches; and (2) the detection and classification of masses and regions of architectural distortion, as benign lesions or malignant tumors, in a unified framework that does not require accurate extraction of the contours of the lesions. The innovative aspects of the work include the design and validation of landmarking algorithms, automatic Tabár masking procedures, and various feature descriptors for quantification of similarity and for contour independent classification of mammographic lesions. Characterization of breast tissue patterns is achieved by means of multidirectional Gabor filters. For the classification tasks, pattern recognition strategies, including Fisher linear discriminant analysis, Bayesian classifiers, support vector machines, and neural networks are applied using automatic selection of features and cross-validation techniques. Computer-aided detection of bilateral asymmetry resulted in accuracy up to 0.94, with sensitivity and specificity of 1 and 0.88, respectively. Computer-aided diagnosis of automatically detected lesions provided sensitivity of detection of malignant tumors in the range of [0.70, 0.81] at a range of falsely detected tumors of [0.82, 3.47] per image. The techniques presented in this work are effective in detecting and characterizing various mammographic signs of breast disease.

Medical Equipment Maintenance

Author : Binseng Wang
Publisher : Springer Nature
ISBN 13 : 3031016556
Total Pages : 76 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Medical Equipment Maintenance by : Binseng Wang

Download or read book Medical Equipment Maintenance written by Binseng Wang and published by Springer Nature. This book was released on 2022-05-31 with total page 76 pages. Available in PDF, EPUB and Kindle. Book excerpt: In addition to being essential for safe and effective patient care, medical equipment also has significant impact on the income and, thus, vitality of healthcare organizations. For this reason, its maintenance and management requires careful supervision by healthcare administrators, many of whom may not have the technical background to understand all of the relevant factors. This book presents the basic elements of medical equipment maintenance and management required of healthcare leaders responsible for managing or overseeing this function. It will enable these individuals to understand their professional responsibilities, as well as what they should expect from their supervised staff and how to measure and benchmark staff performance against equivalent performance levels at similar organizations. The book opens with a foundational summary of the laws, regulations, codes, and standards that are applicable to the maintenance and management of medical equipment in healthcare organizations. Next, the core functions of the team responsible for maintenance and management are described in sufficient detail for managers and overseers. Then the methods and measures for determining the effectiveness and efficiency of equipment maintenance and management are presented to allow performance management and benchmarking comparisons. The challenges and opportunities of managing healthcare organizations of different sizes, acuity levels, and geographical locations are discussed. Extensive bibliographic sources and material for further study are provided to assist students and healthcare leaders interested in acquiring more detailed knowledge. Table of Contents: Introduction / Regulatory Framework / Core Functions of Medical Equipment Maintenance and Management / CE Department Management / Performance Management / Discussion and Conclusions

Chronobioengineering

Author : Donald McEachron
Publisher : Springer Nature
ISBN 13 : 303101653X
Total Pages : 264 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Chronobioengineering by : Donald McEachron

Download or read book Chronobioengineering written by Donald McEachron and published by Springer Nature. This book was released on 2022-06-01 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book represents the first in a two-volume set on biological rhythms. This volume focuses on supporting the claim that biological rhythms are universal and essential characteristics of living organisms, critical for proper functioning of any living system. The author begins by examining the potential reasons for the evolution of biological rhythms: (1) the need for complex, goal-oriented devices to control the timing of their activities; (2) the inherent tendency of feedback control systems to oscillate; and (3) the existence of stable and powerful geophysical cycles to which all organisms must adapt. To investigate the second reason, the author enlists the help of biomedical engineering students to develop mathematical models of various biological systems. One such model involves a typical endocrine feedback system. By adjusting various model parameters, it was found that creating a oscillation in any component of the model generated a rhythmic cascade that made the entire system oscillate. This same approach was used to show how daily light/dark cycles could cascade rhythmic patterns throughout ecosystems and within organisms. Following up on these results, the author discusses how the twin requirements of internal synchronization (precise temporal order necessary for the proper functioning of organisms as complex, goal-oriented devices) and external synchronization (aligning organisms' behavior and physiology with geophysical cycles) supported the evolution of biological clocks. The author then investigates the clock systems that evolved using both conceptual and mathematical models, with the assistance of Dr. Bahrad Sokhansanj, who contributes a chapter on mathematical formulations and models of rhythmic phenomena. With the ubiquity of biological rhythms established, the author suggests a new classification system: the F4LM approach (Function; Frequency; waveForm; Flexibility; Level of biological system expressing rhythms; and Mode of rhythm generation) to investigate biological rhythms. This approach is first used on the more familiar cardiac cycle and then on neural rhythms as exemplified and measured by the electroencephalogram. During the process of investigating neural cycles, the author finds yet another reason for the evolution of biological rhythms: physical constraints, such as those imposed upon long distance neural signaling. In addition, a common theme emerges of a select number of autorhythmic biological oscillators imposing coherent rhythmicity on a larger network or system. During the course of the volume, the author uses a variety of observations, models, experimental results, and arguments to support the original claim of the importance and universality of biological rhythms. In Volume 2, the author will move from the establishment of the critical nature of biological rhythms to how these phenomena may be used to improve human health, well-being, and productivity. In a sense, Volume 1 focuses on the chronobio aspect of chronobioengineering while Volume 2 investigates methods of translating this knowledge into applications, the engineering aspect of chronobioengineering. Table of Contents: Time and Time Again / Walking on Air: An Empirical Proof-of-Concept / Clock Tech, Part 1 / Clock Tech II From External to Internal Timers / Clock Tech III Rise of the CircaRhythms / The Circle Game: Mathematics, Models, and Rhythms / The Power of Circular Reasoning

Models of Horizontal Eye Movements, Part II

Author : John Enderle
Publisher : Springer Nature
ISBN 13 : 3031016432
Total Pages : 148 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Models of Horizontal Eye Movements, Part II by : John Enderle

Download or read book Models of Horizontal Eye Movements, Part II written by John Enderle and published by Springer Nature. This book was released on 2022-06-01 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are five different types of eye movements: saccades, smooth pursuit, vestibular ocular eye movements, optokinetic eye movements, and vergence eye movements. The purpose of this book is focused primarily on mathematical models of the horizontal saccadic eye movement system and the smooth pursuit system, rather than on how visual information is processed. A saccade is a fast eye movement used to acquire a target by placing the image of the target on the fovea. Smooth pursuit is a slow eye movement used to track a target as it moves by keeping the target on the fovea. The vestibular ocular movement is used to keep the eyes on a target during brief head movements. The optokinetic eye movement is a combination of saccadic and slow eye movements that keeps a full-field image stable on the retina during sustained head rotation. Each of these movements is a conjugate eye movement, that is, movements of both eyes together driven by a common neural source. A vergence movement is a non-conjugate eye movement allowing the eyes to track targets as they come closer or farther away. In this book, a 2009 version of a state-of-the-art model is presented for horizontal saccades that is 3rd-order and linear, and controlled by a physiologically based time-optimal neural network. The oculomotor plant and saccade generator are the basic elements of the saccadic system. The control of saccades is initiated by the superior colliculus and terminated by the cerebellar fastigial nucleus, and involves a complex neural circuit in the mid brain. This book is the second part of a book series on models of horizontal eye movements. Table of Contents: 2009 Linear Homeomorphic Saccadic Eye Movement Model and Post-Saccade Behavior: Dynamic and Glissadic Overshoot / Neural Network for the Saccade Controller

Understanding Atrial Fibrillation

Author : Luca Mainardi
Publisher : Springer Nature
ISBN 13 : 3031016327
Total Pages : 122 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Understanding Atrial Fibrillation by : Luca Mainardi

Download or read book Understanding Atrial Fibrillation written by Luca Mainardi and published by Springer Nature. This book was released on 2022-05-31 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book presents recent advances in signal processing techniques for modeling, analysis, and understanding of the heart's electrical activity during atrial fibrillation. This arrhythmia is the most commonly encountered in clinical practice and its complex and metamorphic nature represents a challenging problem for clinicians, engineers, and scientists. Research on atrial fibrillation has stimulated the development of a wide range of signal processing tools to better understand the mechanisms ruling its initiation, maintenance, and termination. This book provides undergraduate and graduate students, as well as researchers and practicing engineers, with an overview of techniques, including time domain techniques for atrial wave extraction, time-frequency analysis for exploring wave dynamics, and nonlinear techniques to characterize the ventricular response and the organization of atrial activity. The book includes an introductory chapter about atrial fibrillation and its mechanisms, treatment, and management. The successive chapters are dedicated to the analysis of atrial signals recorded on the body surface and to the quantification of ventricular response. The rest of the book explores techniques to characterize endo- and epicardial recordings and to model atrial conduction. Under the appearance of being a monothematic book on atrial fibrillation, the reader will not only recognize common problems of biomedical signal processing but also discover that analysis of atrial fibrillation is a unique challenge for developing and testing novel signal processing tools. Table of Contents: Analysis of Ventricular Response During Atrial Fibrillation / Organization Measures of Atrial Activity During Fibrillation / Modeling Atrial Fibrillation: From Myocardial Cells to ECG / Algorithms for Atrial Tachyarrythmia Detection for Long-Term Monitoring with Implantable Devices

Phonocardiography Signal Processing

Author : Abbas K. Abbas
Publisher : Springer Nature
ISBN 13 : 3031016378
Total Pages : 194 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Phonocardiography Signal Processing by : Abbas K. Abbas

Download or read book Phonocardiography Signal Processing written by Abbas K. Abbas and published by Springer Nature. This book was released on 2022-05-31 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: The auscultation method is an important diagnostic indicator for hemodynamic anomalies. Heart sound classification and analysis play an important role in the auscultative diagnosis. The term phonocardiography refers to the tracing technique of heart sounds and the recording of cardiac acoustics vibration by means of a microphone-transducer. Therefore, understanding the nature and source of this signal is important to give us a tendency for developing a competent tool for further analysis and processing, in order to enhance and optimize cardiac clinical diagnostic approach. This book gives the reader an inclusive view of the main aspects in phonocardiography signal processing. Table of Contents: Introduction to Phonocardiography Signal Processing / Phonocardiography Acoustics Measurement / PCG Signal Processing Framework / Phonocardiography Wavelets Analysis / Phonocardiography Spectral Analysis / PCG Pattern Classification / Special Application of Phonocardiography / Phonocardiography Acoustic Imaging and Mapping

Computer-Aided Detection of Architectural Distortion in Prior Mammograms of Interval Cancer

Author : Shantanu Banik
Publisher : Springer Nature
ISBN 13 : 3031016564
Total Pages : 176 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Computer-Aided Detection of Architectural Distortion in Prior Mammograms of Interval Cancer by : Shantanu Banik

Download or read book Computer-Aided Detection of Architectural Distortion in Prior Mammograms of Interval Cancer written by Shantanu Banik and published by Springer Nature. This book was released on 2022-05-31 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt: Architectural distortion is an important and early sign of breast cancer, but because of its subtlety, it is a common cause of false-negative findings on screening mammograms. Screening mammograms obtained prior to the detection of cancer could contain subtle signs of early stages of breast cancer, in particular, architectural distortion. This book presents image processing and pattern recognition techniques to detect architectural distortion in prior mammograms of interval-cancer cases. The methods are based upon Gabor filters, phase portrait analysis, procedures for the analysis of the angular spread of power, fractal analysis, Laws' texture energy measures derived from geometrically transformed regions of interest (ROIs), and Haralick's texture features. With Gabor filters and phase-portrait analysis, 4,224 ROIs were automatically obtained from 106 prior mammograms of 56 interval-cancer cases, including 301 true-positive ROIs related to architectural distortion, and from 52 mammograms of 13 normal cases. For each ROI, the fractal dimension, the entropy of the angular spread of power, 10 Laws' texture energy measures, and Haralick's 14 texture features were computed. The areas under the receiver operating characteristic (ROC) curves obtained using the features selected by stepwise logistic regression and the leave-one-image-out method are 0.77 with the Bayesian classifier, 0.76 with Fisher linear discriminant analysis, and 0.79 with a neural network classifier. Free-response ROC analysis indicated sensitivities of 0.80 and 0.90 at 5.7 and 8.8 false positives (FPs) per image, respectively, with the Bayesian classifier and the leave-one-image-out method. The present study has demonstrated the ability to detect early signs of breast cancer 15 months ahead of the time of clinical diagnosis, on the average, for interval-cancer cases, with a sensitivity of 0.8 at 5.7 FP/image. The presented computer-aided detection techniques, dedicated to accurate detection and localization of architectural distortion, could lead to efficient detection of early and subtle signs of breast cancer at pre-mass-formation stages. Table of Contents: Introduction / Detection of Early Signs of Breast Cancer / Detection and Analysis of Oriented Patterns / Detection of Potential Sites of Architectural Distortion / Experimental Set Up and Datasets / Feature Selection and Pattern Classification / Analysis of Oriented Patterns Related to Architectural Distortion / Detection of Architectural Distortion in Prior Mammograms / Concluding Remarks