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The Effects Of Drugs Upon Synaptic Transmission In The Isolated Spinal Cord Of The Frog
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Book Synopsis Somatosensory System by : Ainsley Iggo
Download or read book Somatosensory System written by Ainsley Iggo and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 861 pages. Available in PDF, EPUB and Kindle. Book excerpt: The waterproof sensory sheet covering the mammalian body has a rich afferent innervation which provides an abundance of complex information for use by the central nervous system often in conjunction with information from receptors in the joints. This book is an attempt to provide a systematic account of the way in which this somatosensory system works. The properties of the peripheral receptors have been debated in scientific terms for about a century and the resolu tion of the conflict in favour of the existence of 'specific' receptors for mechanical, thermal and noxious stimuli is reported and discussed in the opening chapters of the book. An awareness of this specificity has forced a re-consideration of the ways in which the central nervous system de-codes the information which is showered upon it. Advances in knowledge of the fine structure of the central nervous system have raised functional questions about the operation and organisation of the sensory systems in the spinal cord and brain. Fresh insight into the morphological complexity of the dorsal horn and higher levels of the nervous system gives the physiologist a clearer idea of the units with which he works. Progress has been made in understanding the function of sensory relay nuclei in general and indivi dual tracts in particular and is fully decomented.
Download or read book Cumulated Index Medicus written by and published by . This book was released on 1985 with total page 1094 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Psychopharmacology Abstracts written by and published by . This book was released on 1981 with total page 562 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Handbook of the Spinal Cord: Pharmacology by : Robert A. Davidoff
Download or read book Handbook of the Spinal Cord: Pharmacology written by Robert A. Davidoff and published by . This book was released on 1983 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Pharmacology of Ganglionic Transmission by : D.A. Kharkevich
Download or read book Pharmacology of Ganglionic Transmission written by D.A. Kharkevich and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: D.A. KHARKEVICH The history of the study of ganglionic substances begins with the paper of LANGLEY and DICKINSON (1889), who established the ability of nicotine to block the neurones in the superior cervical ganglion. This was a considerable discovery as the authors ascertained that impulses were transmitted from pre- to postganglionic neurones in the autonomic ganglia. Simultaneously they indicated the possibility of pharmaco logical influence upon interneuronal transmission in autonomic ganglia. The idea of ganglionic receptors specifically sensitive to nicotine followed logically. Later, LANGLEY (1905, 1906) considered the problem of receptors with respect to neuro-effector synapses. It is remarkable that he was one of the first to put forward the theory of chemical mediation of excitation (" ... the nervous impulse should not pass from nerve to muscle by an electric discharge, but by the secretion of a special substance at the end of the nerve": LANGLEY, 1906, p. 183). In addition, LANGLEY JOHN N. LANGLEY (1852-1926) D.A. KHARKEVICH 2 and his collaborators managed to define the topography of autonomic ganglia more precisely by means of nicotine. It should be mentioned that it was he who introduced the terms "autonomic nervous system" and "parasympathetic nervous system".
Book Synopsis Indexes to the Epilepsy Accessions of the Epilepsy Information System by : J. Kiffin Penry
Download or read book Indexes to the Epilepsy Accessions of the Epilepsy Information System written by J. Kiffin Penry and published by . This book was released on 1978 with total page 1366 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Epilepsy Bibliography 1950-1975 by : J. Kiffin Penry
Download or read book Epilepsy Bibliography 1950-1975 written by J. Kiffin Penry and published by . This book was released on 1976 with total page 1876 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Antiepileptic Drugs by : Hans-Hasso Frey
Download or read book Antiepileptic Drugs written by Hans-Hasso Frey and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 871 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epileptic disorders need treatment for many years or even for life, and this makes a thorough understanding of the pharmacokinetics and possible hazards and side effects of the drugs used in treatment mandatory. During recent decades our knowledge in this field has considerably increased, not least as a result of the development of specific and sensitive methods for the determination of anti epileptic agents in biological material. The clinical pharmacology of this group of drugs has been studied extensively and can today be regarded as well established. This does not necessarily mean that drug treatment of epilepsy is without problems. For example, it has recently been shown that one of the newer anti epileptic drugs, greeted with great enthusiasm by clinicians, may in rare instances induce serious damage to the liver and the pancreas, and seems even to have a certain teratogenic potential. Clinical problems should be understood as a challenge to the experimental pharmacologist, who should try to find explanations for the clinical hazards, and, if possible, show new ways in which better drugs might be developed. In recent years interest has focused on the importance of the inhibitory transmitter 'l'-aminobutyric acid (GABA) in the pathophysiology of epilepsy, and there have been a series of attempts to find useful antiepileptic drugs among substances interfering with GABA metabolism in the CNS.
Download or read book Research Awards Index written by and published by . This book was released on 1985 with total page 1436 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Theses and Dissertations Accepted for the Degrees of M. Phil. and Ph.D. by : University of London
Download or read book Theses and Dissertations Accepted for the Degrees of M. Phil. and Ph.D. written by University of London and published by . This book was released on 1976 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Neurotransmitters written by P. Simon and published by Elsevier. This book was released on 2013-10-22 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Pharmacology and Therapeutics, Volume 2: Neurotransmitters contains the proceedings of the 7th International Congress of Pharmacology held in Paris, France, in 1978. The papers explore advances in the understanding of neurotransmitters, their pharmacology, and their therapeutic applications. Topics covered range from the functions of GABA to the interdependence of neurotransmitter systems in the central nervous system (CNS). This volume is comprised of 24 chapters and opens with a discussion on the role of GABA systems in Huntington's disease and schizophrenia. The reader is then introduced to the stereospecific actions of GABA analogues; interactions between serotonin and noradrenalin containing neurons; immunofluorescent staining of serotonin in the CNS; and plasticity of transmitter functions in sympathetic neurons developing in cell culture. The following chapters explore the molecular mechanisms underlying the modulation of catecholamine release from the adrenal medulla; pre-and postsynaptic regulation of catecholamine neurotransmitters; the role of GABA-ergic component in the mechanism of action of neurotropic drugs; and pre-and postsynaptic action of GABA in the mammalian spinal cord. This book will be of interest to practitioners in biosciences, pharmacology, physiology, and medicine.
Book Synopsis PROGRESS IN NONMAMMALIAN BRAIN RESEARCH by : Nistico
Download or read book PROGRESS IN NONMAMMALIAN BRAIN RESEARCH written by Nistico and published by Springer. This book was released on 1983-05-25 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Psychotropic Agents written by and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 796 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second volume continues the description of the psychotropic agents and discusses anxiolytics, gerontopsychopharmacological agents, and psychomotor stimulants. Of these groups of substances, most of this volume has been devoted to anxiolytics as the authors have endeavored to convey as complete a picture as possible. The editors are of the opinion that particular attention should be given to anxiolytics with regard to their range of administration as this is the most frequently prescribed group of psychotropic drugs. In contrast to neuroleptics and thymoleptics, anxiolytics are a class of psychotropic drugs whose therapeutic effect can be recognized in animal experiments to some extent. This, together with the analysis of the biochemical mechanisms of their actions, permits a better understanding of material processes in the brain accompanying the emotions: anxiety and tension. For the first time in the history of the Handbook the editors have devoted a whole chapter to gerontopsychopharmacological agents. In doing so they are also aware of the risk they are taking, at least from a pharmacological point of view, as gerontopsychopharmacological agents are an insufficiently defined and extremely heterogeneous group of substances. The only denominator the various subgroups of these agents have in common is that they are given in cases of dysfunctions, disorders, and diseases of the brain occurring mainly in the elderly.
Download or read book Psychopharmacology Abstracts written by and published by . This book was released on 1982 with total page 868 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :National Institutes of Health (U.S.). Division of Research Grants Publisher : ISBN 13 : Total Pages :1212 pages Book Rating :4.3/5 (91 download)
Book Synopsis Research Grants Index by : National Institutes of Health (U.S.). Division of Research Grants
Download or read book Research Grants Index written by National Institutes of Health (U.S.). Division of Research Grants and published by . This book was released on 1975 with total page 1212 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Psychopharmacology Bulletin written by and published by . This book was released on 1986 with total page 1188 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Frog Neurobiology written by R. Llinas and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 1056 pages. Available in PDF, EPUB and Kindle. Book excerpt: In review, the amount of information available on the morphological and func tional properties of the frog nervous system is very extensive indeed and in certain areas is the only available source of information in vertebrates. Further more, much of the now classical knowledge in neurobiology was originally ob tained and elaborated in depth in this vertebrate. To cite only a few examples, studies of nerve conduction, neuromuscular transmission, neuronal integration, sense organs, development, and locomotion have been developed with great detail in the frog and in conjunction provide the most complete holistic descrip tion of any nervous system. Added to the above considerations, the ease with which these animals may be maintained (both as adults and during development) and the advantage of their lower cost as compared with other vertebrate forms make the frog one of the most important laboratory animals in neurobiology. With these thoughts in mind, we decided to compile this volume. Our goal in doing so was to assemble as much as possible of the information available on frog neurobiology and to have the different topics covered by authorities in each of the fields represented. To keep the handbook restricted to one volume, we found it necessary to omit the large field of amphibian muscle neurobiology, which has already been summarized in various other publications.
