The Effect Of Hypoxic Metabolic Acidosis On Cardiac Output

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Hypoxia, Metabolic Acidosis, and the Circulation

Author : Allen I. Arieff
Publisher : Springer
ISBN 13 : 1461475422
Total Pages : 221 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Hypoxia, Metabolic Acidosis, and the Circulation by : Allen I. Arieff

Download or read book Hypoxia, Metabolic Acidosis, and the Circulation written by Allen I. Arieff and published by Springer. This book was released on 2013-05-27 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, there has been a wealth of new information on the physiological and biochemical consequences of hypoxia, or low blood levels of oxygen. This new volume discusses the implications of these new findings on the pathophysiology, development, and treatment of hypoxic metabolic acidosis. The volume is part of the Clinical Physiology series sponsored by the American Physiological Society, and is based on a FASEB symposium held in May 1988. Hypoxia was once thought to affect organs in a similar manner, but it is now known that each is affected differently. The author shows how hypoxia and metabolic acidosis affect the heart, lungs, blood vessels and other organs at the cellular level, the tissue level, and finally, at the level of the entire organ. The book then proceeds to a description of the situations in which hypoxic metabolic acidosis develops, such as during high altitude exposure, cardiac arrest, and lactic acidosis. The last few chapters give an overview of treatment. Traditional therapy has consisted largely of the intravenous administration of sodium bicarbonate. This method has come under increasing scrutiny however, and the range of problems associated with the use of sodium bicarbonate is examined fully. Newer alternative agents for managing hypoxic acidosis are reviewed as well. This up-to-date review of hypoxia and metabolic acidosis should be of interest to physiologists, internists, cardiologists, chest physicians, anesthesiologists, and intensive care specialists.

Regulation of Tissue Oxygenation, Second Edition

Author : Roland N. Pittman
Publisher : Biota Publishing
ISBN 13 : 1615047212
Total Pages : 117 pages
Book Rating : 4.6/5 (15 download)

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Book Synopsis Regulation of Tissue Oxygenation, Second Edition by : Roland N. Pittman

Download or read book Regulation of Tissue Oxygenation, Second Edition written by Roland N. Pittman and published by Biota Publishing. This book was released on 2016-08-18 with total page 117 pages. Available in PDF, EPUB and Kindle. Book excerpt: This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.

Regulation of Coronary Blood Flow

Author : Michitoshi Inoue
Publisher : Springer Science & Business Media
ISBN 13 : 4431683674
Total Pages : 330 pages
Book Rating : 4.4/5 (316 download)

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Book Synopsis Regulation of Coronary Blood Flow by : Michitoshi Inoue

Download or read book Regulation of Coronary Blood Flow written by Michitoshi Inoue and published by Springer Science & Business Media. This book was released on 2013-11-09 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research centering on blood flow in the heart continues to hold an important position, especially since a better understanding of the subject may help reduce the incidence of coronary arterial disease and heart attacks. This book summarizes recent advances in the field; it is the product of fruitful cooperation among international scientists who met in Japan in May, 1990 to discuss the regulation of coronary blood flow.

Oxford Textbook of Critical Care

Author : Webb
Publisher : Oxford University Press
ISBN 13 : 0198855435
Total Pages : 1961 pages
Book Rating : 4.1/5 (988 download)

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Book Synopsis Oxford Textbook of Critical Care by : Webb

Download or read book Oxford Textbook of Critical Care written by Webb and published by Oxford University Press. This book was released on 2020-01-10 with total page 1961 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in paperback, the second edition of the Oxford Textbook of Critical Care is a comprehensive multi-disciplinary text covering all aspects of adult intensive care management. Uniquely this text takes a problem-orientated approach providing a key resource for daily clinical issues in the intensive care unit. The text is organized into short topics allowing readers to rapidly access authoritative information on specific clinical problems. Each topic refers to basic physiological principles and provides up-to-date treatment advice supported by references to the most vital literature. Where international differences exist in clinical practice, authors cover alternative views. Key messages summarise each topic in order to aid quick review and decision making. Edited and written by an international group of recognized experts from many disciplines, the second edition of the Oxford Textbook of Critical Careprovides an up-to-date reference that is relevant for intensive care units and emergency departments globally. This volume is the definitive text for all health care providers, including physicians, nurses, respiratory therapists, and other allied health professionals who take care of critically ill patients.

The ESC Textbook of Intensive and Acute Cardiovascular Care

Author : Marco Tubaro
Publisher : Oxford University Press
ISBN 13 : 0192589199
Total Pages : 800 pages
Book Rating : 4.1/5 (925 download)

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Book Synopsis The ESC Textbook of Intensive and Acute Cardiovascular Care by : Marco Tubaro

Download or read book The ESC Textbook of Intensive and Acute Cardiovascular Care written by Marco Tubaro and published by Oxford University Press. This book was released on 2021-03-08 with total page 800 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ESC Textbook of Intensive and Acute Cardiovascular Care is the official textbook of the Acute Cardiovascular Care Association (ACVC) of the ESC. Cardiovascular diseases (CVDs) are a major cause of premature death worldwide and a cause of loss of disability-adjusted life years. For most types of CVD early diagnosis and intervention are independent drivers of patient outcome. Clinicians must be properly trained and centres appropriately equipped in order to deal with these critically ill cardiac patients. This new updated edition of the textbook continues to comprehensively approach all the different issues relating to intensive and acute cardiovascular care and addresses all those involved in intensive and acute cardiac care, not only cardiologists but also critical care specialists, emergency physicians and healthcare professionals. The chapters cover the various acute cardiovascular diseases that need high quality intensive treatment as well as organisational issues, cooperation among professionals, and interaction with other specialities in medicine. SECTION 1 focusses on the definition, structure, organisation and function of ICCU's, ethical issues and quality of care. SECTION 2 addresses the pre-hospital and immediate in-hospital (ED) emergency cardiac care. SECTIONS 3-5 discuss patient monitoring, diagnosis and specific procedures. Acute coronary syndromes (ACS), acute decompensated heart failure (ADHF), and serious arrhythmias form SECTIONS 6-8. The main other cardiovascular acute conditions are grouped in SECTION 9. Finally SECTION 10 is dedicated to the many concomitant acute non-cardiovascular conditions that contribute to the patients' case mix in ICCU. This edition includes new chapters such as low cardiac output states and cardiogenic shock, and pacemaker and ICDs: troubleshooting and chapters have been extensively revised. Purchasers of the print edition will also receive an access code to access the online version of the textbook which includes additional figures, tables, and videos to better to better illustrate diagnostic and therapeutic techniques and procedures in IACC. The third edition of the ESC Textbook of Intensive and Acute Cardiovascular Care will establish a common basis of knowledge and a uniform and improved quality of care across the field.

Metabolic Acidosis

Author : Donald E.Wesson
Publisher : Springer
ISBN 13 : 1493934635
Total Pages : 164 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Metabolic Acidosis by : Donald E.Wesson

Download or read book Metabolic Acidosis written by Donald E.Wesson and published by Springer. This book was released on 2016-04-08 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: This timely volume provides an overview to the causes, effects on systems and clinical approaches of metabolic acidosis. Beginning with a basic understanding of the physiology, pathophysiology and development of this disease, subsequent chapters cover the characteristics and context of the processes that can cause it and a thorough presentation of management strategies. Recommended treatments include those carried out by the health care provider as well as the individual patient, such as dietary management. Clinicians and healthcare professionals will find the tools needed to recognize, work up and manage patients with metabolic acidosis in this practical and concise resource.

Cardiovascular Regulation

Author : David Jordan
Publisher : Ashgate Publishing
ISBN 13 : 9781855780248
Total Pages : 159 pages
Book Rating : 4.7/5 (82 download)

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Book Synopsis Cardiovascular Regulation by : David Jordan

Download or read book Cardiovascular Regulation written by David Jordan and published by Ashgate Publishing. This book was released on 1995 with total page 159 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Studies in Physiology series provides a concise introduction to developments in complex areas of physiology for a wide audience. Published on behalf of the Physiology Society, Cardiovascular Regulation provides an up-to-date account of our current understanding of the control of the cardiovascular system that is not covered by existing textbooks. Both students and lecturers of cardiovascular and exercise physiology, medicine, dentistry and biomedical sciences will find this book informative and easy to read. Each chapter has numerous summary boxes. 'Essential reading' suggestions provide additional reading for undergraduates and the suggestions for 'Further reading' cover the subject to postgraduate level.

Pulmonary Gas Exchange

Author : G. Kim Prisk
Publisher : Biota Publishing
ISBN 13 : 1615044515
Total Pages : 88 pages
Book Rating : 4.6/5 (15 download)

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Book Synopsis Pulmonary Gas Exchange by : G. Kim Prisk

Download or read book Pulmonary Gas Exchange written by G. Kim Prisk and published by Biota Publishing. This book was released on 2013-08-01 with total page 88 pages. Available in PDF, EPUB and Kindle. Book excerpt: The lung receives the entire cardiac output from the right heart and must load oxygen onto and unload carbon dioxide from perfusing blood in the correct amounts to meet the metabolic needs of the body. It does so through the process of passive diffusion. Effective diffusion is accomplished by intricate parallel structures of airways and blood vessels designed to bring ventilation and perfusion together in an appropriate ratio in the same place and at the same time. Gas exchange is determined by the ventilation-perfusion ratio in each of the gas exchange units of the lung. In the normal lung ventilation and perfusion are well matched, and the ventilation-perfusion ratio is remarkably uniform among lung units, such that the partial pressure of oxygen in the blood leaving the pulmonary capillaries is less than 10 Torr lower than that in the alveolar space. In disease, the disruption to ventilation-perfusion matching and to diffusional transport may result in inefficient gas exchange and arterial hypoxemia. This volume covers the basics of pulmonary gas exchange, providing a central understanding of the processes involved, the interactions between the components upon which gas exchange depends, and basic equations of the process.

Clinical Aspects of O2 Transport and Tissue Oxygenation

Author : K. Reinhart
Publisher : Springer
ISBN 13 :
Total Pages : 532 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Clinical Aspects of O2 Transport and Tissue Oxygenation by : K. Reinhart

Download or read book Clinical Aspects of O2 Transport and Tissue Oxygenation written by K. Reinhart and published by Springer. This book was released on 1989-10-27 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt: All aspects of oxygen transport and tissue oxygenation that are relevant in clinical medicine are covered in this monograph. Experts from basic science as well as clinical research provide information that improves understanding of how to treat O2-transport disturbances in daily practice. Special interest is focussed on the question of supply dependency of O2-uptake and its role in multi-organ failure in the critically ill. Other topics are the clinical monitoring of O2-transport and O2-utilisation, oxygen toxicity, and the role of O2-radicals and the reperfusion syndrome in organ transplantation and cardiopulmonary resuscitation.

Handbook of CTG Interpretation

Author : Edwin Chandraharan
Publisher : Cambridge University Press
ISBN 13 : 1107485509
Total Pages : 257 pages
Book Rating : 4.1/5 (74 download)

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Book Synopsis Handbook of CTG Interpretation by : Edwin Chandraharan

Download or read book Handbook of CTG Interpretation written by Edwin Chandraharan and published by Cambridge University Press. This book was released on 2017-02-23 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practical manual promotes an evidence-based paradigm of fetal heart rate monitoring during labour, moving away from the traditional 'pattern-based' interpretation to physiology-based interpretation. Aimed at obstetricians and midwives, it is useful to all those involved in multiprofessional intrapartum care.

Respiratory Muscle Training

Author : Alison McConnell
Publisher : Elsevier Health Sciences
ISBN 13 : 0702054550
Total Pages : 403 pages
Book Rating : 4.7/5 (2 download)

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Book Synopsis Respiratory Muscle Training by : Alison McConnell

Download or read book Respiratory Muscle Training written by Alison McConnell and published by Elsevier Health Sciences. This book was released on 2013-04-18 with total page 403 pages. Available in PDF, EPUB and Kindle. Book excerpt: Respiratory Muscle Training: theory and practice is the world's first book to provide an "everything-you-need-to-know" guide to respiratory muscle training (RMT). Authored by an internationally-acclaimed expert, it is an evidence-based resource, built upon current scientific knowledge, as well as experience at the cutting-edge of respiratory training in a wide range of settings. The aim of the book is to give readers: 1) an introduction to respiratory physiology and exercise physiology, as well as training theory; 2) an understanding of how disease affects the respiratory muscles and the mechanics of breathing; 3) an insight into the disease-specific, evidence-based benefits of RMT; 4) advice on the application of RMT as a standalone treatment, and as part of a rehabilitation programme; and finally, 5) guidance on the application of functional training techniques to RMT. The book is divided into two parts – theory and practice. Part I provides readers with access to the theoretical building blocks that support practice. It explores the evidence base for RMT as well as the different methods of training respiratory muscles and their respective efficacy. Part II guides the reader through the practical implementation of the most widely validated form of RMT, namely inspiratory muscle resistance training. Finally, over 150 "Functional" RMT exercises are described, which incorporate a stability and/or postural challenge – and address specific movements that provoke dyspnoea. Respiratory Muscle Training: theory and practice is supported by a dedicated website (www.physiobreathe.com), which provides access to the latest information on RMT, as well as video clips of all exercises described in the book. Purchasers will also receive a three-month free trial of the Physiotec software platform (via www.physiotec.ca), which allows clinicians to create bespoke training programmes (including video clips) that can be printed or emailed to patients. - Introductory overviews of respiratory and exercise physiology, as well as training theory - Comprehensive, up-to-date review of respiratory muscle function, breathing mechanics and RMT - Analysis of the interaction between disease and respiratory mechanics, as well as their independent and combined influence upon exercise tolerance - Analysis of the rationale and application of RMT to over 20 clinical conditions, e.g., COPD, heart failure, obesity, mechanical ventilation - Evidence-based guidance on the implementation of inspiratory muscle resistance training - Over 150 functional exercises that incorporate a breathing challenge - www.physiobreathe.com - access up-to-date information, video clips of exercises and a three-month free trial of Physiotec's RMT exercise module (via www.physiotec.ca)

Core Topics in Airway Management

Author : Ian Calder
Publisher : Cambridge University Press
ISBN 13 : 9781139443043
Total Pages : 230 pages
Book Rating : 4.4/5 (43 download)

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Book Synopsis Core Topics in Airway Management by : Ian Calder

Download or read book Core Topics in Airway Management written by Ian Calder and published by Cambridge University Press. This book was released on 2005-01-06 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an easy-to-read introduction to this important topic that will be of value to a wide spectrum of healthcare professionals including anaesthetists, intensivists, ODPs, theatre and recovery nurses. Concise but comprehensive chapters from experts in the field cover everything from basic anatomy, physiology and applied physics, through the various methods of maintaining the airway under anaesthesia (supraglottic devices, tracheal intubation, tubes/cuffs, endobronchial and double-lumen tubes) to the problem airway (obstruction by infection, tumour or a foreign body, ENT and maxillo-facial surgery, aspiration, obstetrics, trauma, cervical spine disease, intensive care, the 'lost' airway, extubation and recovery), the paediatric airway, disinfection and cleaning of equipment and finally morbidity, mortality and medico-legal issues. 'Real' clinical scenarios, with patient management questions and model answers, are included throughout, to bring to life some of the key problems encountered in day-to-day practice and enhance the book's utility as a teaching and self-learning tool.

Data Interpretation in Anesthesia

Author : Tilak D. Raj
Publisher : Springer
ISBN 13 : 3319558625
Total Pages : 450 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Data Interpretation in Anesthesia by : Tilak D. Raj

Download or read book Data Interpretation in Anesthesia written by Tilak D. Raj and published by Springer. This book was released on 2017-09-09 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focusing on the interpretation of data commonly available to anesthesiologists, this book presents a data point, followed by discussion in a question and answer format. Covering EKG's, X-Rays, MRI's, graphs, paper recordings, blood gas results, laboratory results, patient case histories and more, Data Interpretation in Anesthesia provides an enhanced and stimulating learning format for residents in training and practitioners alike.

Applied Cardiovascular Physiology

Author : Michael Pinsky
Publisher : Springer Science & Business Media
ISBN 13 : 3642606962
Total Pages : 405 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis Applied Cardiovascular Physiology by : Michael Pinsky

Download or read book Applied Cardiovascular Physiology written by Michael Pinsky and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: A concise yet complete overview of the treatment of cardiovascular instability in the critically ill patient. The authors consider all aspects, ranging from basic physiology and pathophysiology to diagnostic tools and established and novel forms of therapy. The whole is rounded off with an integration of these principles into a series of clinically relevant scenarios.

Muir's Textbook of Pathology

Author : C. Simon Herrington
Publisher : CRC Press
ISBN 13 : 1444184989
Total Pages : 606 pages
Book Rating : 4.4/5 (441 download)

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Book Synopsis Muir's Textbook of Pathology by : C. Simon Herrington

Download or read book Muir's Textbook of Pathology written by C. Simon Herrington and published by CRC Press. This book was released on 2019-08-08 with total page 606 pages. Available in PDF, EPUB and Kindle. Book excerpt: Muir's Textbook of Pathology sets a standard in this subject by linking the scientific aspects that underlie pathological processes, relating these to specific organ systems and placing all in a context that the student of medicine or pathology can appreciate and understand. The clearly defined and easy-to-follow structure, enhanced by nume

Tissue Oxygen Utilization

Author : Guillermo Gutierrez
Publisher : Springer Science & Business Media
ISBN 13 : 3642841694
Total Pages : 381 pages
Book Rating : 4.6/5 (428 download)

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Book Synopsis Tissue Oxygen Utilization by : Guillermo Gutierrez

Download or read book Tissue Oxygen Utilization written by Guillermo Gutierrez and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 381 pages. Available in PDF, EPUB and Kindle. Book excerpt: Disturbances in peripheral O extraction can be produced in dogs treated with 2 endotoxin and thereby provide an opportunity to test theories for the origin of pathological O supply dependency or to try different treatment modalities. The 2 most serious deficiency in the current animal models is the inability to mimic the increased O demand that is observed in patients at 02 delivery rates in excess of 2 normal. A particular feature of this increased O demand is that it apparently does 2 not stimulate increased 02 extraction, although the limitation in O extraction has 2 not been explored in patients by lowering 02 supply, for obvious reasons. At least two possibilities to account for increased 02 demand could be investigated in animal models, however. The amount of 02 that is utilized in extramitochondrial pathways, which is normally on the order of 10%, may be greatly increased in ARDS and sepsis by O radical formation. There is presently no information 2 concerning how much 02 might be used in this way. Another strong possibility is that mitochondrial injury, perhaps as a result of 02 radical formation, uncouples oxidative phosphorylation. Some evidence presently in the literature supports this idea [19]. Indeed, the association of increased blood lactate levels with higher than expected 02 demands makes uncoupling a very attractive hypothesis that warrants further investigation in animal models using such agents as 2,4-dinitrophenol. References 1.

Perioperative Hemodynamic Monitoring and Goal Directed Therapy

Author : Maxime Cannesson
Publisher : Cambridge University Press
ISBN 13 : 1316061442
Total Pages : 301 pages
Book Rating : 4.3/5 (16 download)

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Book Synopsis Perioperative Hemodynamic Monitoring and Goal Directed Therapy by : Maxime Cannesson

Download or read book Perioperative Hemodynamic Monitoring and Goal Directed Therapy written by Maxime Cannesson and published by Cambridge University Press. This book was released on 2014-09-04 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique book provides clinicians and administrators with a comprehensive understanding of perioperative hemodynamic monitoring and goal directed therapy, emphasizing practical guidance for implementation at the bedside. Successful hemodynamic monitoring and goal directed therapy require a wide range of skills. This book will enable readers to: • Detail the rationale for using perioperative hemodynamic monitoring systems and for applying goal directed therapy protocols at the bedside • Understand the physiological concepts underlying perioperative goal directed therapy for hemodynamic management • Evaluate hemodynamic monitoring systems in clinical practice • Learn about new techniques for achieving goal directed therapy • Apply goal directed therapy protocols in the perioperative environment (including emergency departments, operating rooms and intensive care units) • Demonstrate clinical utility of GDT and hemodynamic optimization using case presentations. Illustrated with diagrams and case examples, this is an important resource for anesthesiologists, emergency physicians, intensivists and pneumonologists as well as nurses and administrative officers.