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Author : Takashi Nakano
Publisher : Frontiers Media SA
ISBN 13 : 2832510574
Total Pages : 120 pages
Book Rating : 4.8/5 (325 download)
Download or read book The Development of Biomarkers in Psychiatry written by Takashi Nakano and published by Frontiers Media SA. This book was released on 2023-01-03 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Judith Pratt
Publisher : Springer
ISBN 13 : 3319996428
Total Pages : 437 pages
Book Rating : 4.3/5 (199 download)
Download or read book Biomarkers in Psychiatry written by Judith Pratt and published by Springer. This book was released on 2019-01-05 with total page 437 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume addresses one of the Holy Grails in Psychiatry, namely the evidence for and potential to adopt ‘Biomarkers’ for prevention, diagnosis, and treatment responses in mental health conditions. It meshes together state of the art research from international renowned pre-clinical and clinical scientists to illustrate how the fields of anxiety disorders, depression, psychotic disorders, and autism spectrum disorder have advanced in recent years.
Author : Yong-Ku Kim
Publisher : Springer Nature
ISBN 13 : 9813297212
Total Pages : 641 pages
Book Rating : 4.8/5 (132 download)
Download or read book Frontiers in Psychiatry written by Yong-Ku Kim and published by Springer Nature. This book was released on 2019-11-09 with total page 641 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews key recent advances and new frontiers within psychiatric research and clinical practice. These advances either represent or are enabling paradigm shifts in the discipline and are influencing how we observe, derive and test hypotheses, and intervene. Progress in information technology is allowing the collection of scattered, fragmented data and the discovery of hidden meanings from stored data, and the impacts on psychiatry are fully explored. Detailed attention is also paid to the applications of artificial intelligence, machine learning, and data science technology in psychiatry and to their role in the development of new hypotheses, which in turn promise to lead to new discoveries and treatments. Emerging research methods for precision medicine are discussed, as are a variety of novel theoretical frameworks for research, such as theoretical psychiatry, the developmental approach to the definition of psychopathology, and the theory of constructed emotion. The concluding section considers novel interventions and treatment avenues, including psychobiotics, the use of neuromodulation to augment cognitive control of emotion, and the role of the telomere-telomerase system in psychopharmacological interventions.
Author : Chris Turck
Publisher : Springer Science & Business Media
ISBN 13 : 0387792511
Total Pages : 536 pages
Book Rating : 4.3/5 (877 download)
Download or read book Biomarkers for Psychiatric Disorders written by Chris Turck and published by Springer Science & Business Media. This book was released on 2009-04-29 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomarkers hold immense promise for the early detection of disease. Unlike other disorders like diabetes and heart disease where a limited number of biological markers are at hand that allow the physician to come up with a reliable diagnosis, there are currently no such markers available for affective disorders. As in any other disease area a major goal is therefore the identification of early markers that can categorize subsets of subjects in a consistent manner. This will allow a more precise definition and categorization of affective disorders and in turn facilitate investigations of the pathogenesis of the diseases and enhance our ability for treatment. This edited volume will not only address the area of affective disorders but also other brain disorders that are neurological in nature, including Multiple Sclerosis and Alzheimer Disease.
Author : Bernhard Baune
Publisher : Academic Press
ISBN 13 : 0128131772
Total Pages : 604 pages
Book Rating : 4.1/5 (281 download)
Download or read book Personalized Psychiatry written by Bernhard Baune and published by Academic Press. This book was released on 2019-10-16 with total page 604 pages. Available in PDF, EPUB and Kindle. Book excerpt: Personalized Psychiatry presents the first book to explore this novel field of biological psychiatry that covers both basic science research and its translational applications. The book conceptualizes personalized psychiatry and provides state-of-the-art knowledge on biological and neuroscience methodologies, all while integrating clinical phenomenology relevant to personalized psychiatry and discussing important principles and potential models. It is essential reading for advanced students and neuroscience and psychiatry researchers who are investigating the prevention and treatment of mental disorders. Combines neurobiology with basic science methodologies in genomics, epigenomics and transcriptomics Demonstrates how the statistical modeling of interacting biological and clinical information could transform the future of psychiatry Addresses fundamental questions and requirements for personalized psychiatry from a basic research and translational perspective
Author : Matthew L. Baum
Publisher : Oxford University Press
ISBN 13 : 0190236264
Total Pages : 225 pages
Book Rating : 4.1/5 (92 download)
Download or read book The Neuroethics of Biomarkers written by Matthew L. Baum and published by Oxford University Press. This book was released on 2016 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroscientists are mining nucleic acids, fluids, and brain images for biomarkers of risk of brain disorders. This book brings clarity to several debates on the neuroethics of biomarkers by arguing for the abandonment of a categorical concept of disorder (sick vs. well) and the adoption of an explicitly probabilistic one.
Author : Yogesh Dwivedi
Publisher : CRC Press
ISBN 13 : 143983881X
Total Pages : 485 pages
Book Rating : 4.4/5 (398 download)
Download or read book The Neurobiological Basis of Suicide written by Yogesh Dwivedi and published by CRC Press. This book was released on 2012-06-25 with total page 485 pages. Available in PDF, EPUB and Kindle. Book excerpt: With recent studies using genetic, epigenetic, and other molecular and neurochemical approaches, a new era has begun in understanding pathophysiology of suicide. Emerging evidence suggests that neurobiological factors are not only critical in providing potential risk factors but also provide a promising approach to develop more effective treatment and prevention strategies. The Neurobiological Basis of Suicide discusses the most recent findings in suicide neurobiology. Psychological, psychosocial, and cultural factors are important in determining the risk factors for suicide; however, they offer weak prediction and can be of little clinical use. Interestingly, cognitive characteristics are different among depressed suicidal and depressed nonsuicidal subjects, and could be involved in the development of suicidal behavior. The characterization of the neurobiological basis of suicide is in delineating the risk factors associated with suicide. The Neurobiological Basis of Suicide focuses on how and why these neurobiological factors are crucial in the pathogenic mechanisms of suicidal behavior and how these findings can be transformed into potential therapeutic applications.
Author : Jorge Manzanares
Publisher : Frontiers Media SA
ISBN 13 : 2889713016
Total Pages : 205 pages
Book Rating : 4.8/5 (897 download)
Download or read book The Search for Biomarkers in Psychiatry written by Jorge Manzanares and published by Frontiers Media SA. This book was released on 2021-09-14 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Margareth Borges Coutinho Gallo
Publisher : Springer Nature
ISBN 13 : 3031590287
Total Pages : 259 pages
Book Rating : 4.0/5 (315 download)
Download or read book Seeking Molecular Biomarkers for Schizophrenia Using ROC Analysis written by Margareth Borges Coutinho Gallo and published by Springer Nature. This book was released on with total page 259 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Matthew Macaluso
Publisher : Springer Nature
ISBN 13 : 3031210549
Total Pages : 457 pages
Book Rating : 4.0/5 (312 download)
Download or read book Drug Development in Psychiatry written by Matthew Macaluso and published by Springer Nature. This book was released on 2023-03-16 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book reviews clinical trial methodology as it pertains to drug development in psychiatry. The reader will understand the process of drug development in psychiatry from discovery through marketing with the help of clinically relevant examples. The reader will appreciate the history of drug development in psychiatry dating back to the era of serendipitous discovery and culminating in an era of new and highly focused targets. Readers will understand how drug development in psychiatry has changed and adapted with the discovery of novel mechanism of action drugs. Novel drugs and disease targets have changed the way developers and regulatory agencies think about clinical trial methodology. The book elucidates how biomarkers, genetics and advances in neuroscience and neuroimaging have influenced drug development approaches, which will ultimately change the practice of psychiatry. The book will be broken down into the following sections: a. Prior to the 1960s - Drug discovery by chance observation b. The last 50 years – refined targeting of CNS drugs without the discovery of mechanistically new drugs c. The future – the discovery and development of mechanistically new drugs. The examination of new targets, genetics and biomarkers.
Author : Willem Bruin
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (142 download)
Download or read book Neuroimaging Biomarkers for Psychiatry written by Willem Bruin and published by . This book was released on 2024 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Diagnosis in psychiatry relies on the subjective assessment of symptoms, both reported by patients and observed by clinicians. This purely symptom-based classification has its limitations. Patients with the same diagnosis express different symptoms, and there is considerable overlap in symptoms across different mental disorders, leading to the possibility of over- or misdiagnosis. Moreover, these diagnoses tell us little about the individual patient, as treatment guidelines tend to follow a one-size-fits-all approach that may not be effective for every patient, resulting in delayed or ineffective treatment for some. To address these issues, there has been a shift towards more objective approaches to diagnosis and personalized treatment in psychiatry . An important means to this end is the search for objective biomarkers , which are measurable characteristics that indicate normal (neuro)biological processes or responses to therapeutic intervention. These biomarkers could help clinicians make more evidence-based decisions that are tailored to individual patients, potentially leading to more efficient and effective psychiatric care. The aim of this thesis was to investigate whether machine learning techniques could be used to find generalizable biomarkers for various psychiatric disorders. We used neuroimaging data to develop diagnostic biomarkers for OCD, (trans)diagnostic biomarkers for anxiety disorders in juveniles, and biomarkers predictive for ECT treatment outcome in patients with depression. This thesis showed that machine learning techniques can be applied to predict diagnosis and treatment outcome with variable success. Future studies should carefully consider sources of heterogeneity to facilitate the development of more accurate and clinically relevant biomarkers, ultimately improving psychiatric care."--
Author : Marek Kubicki
Publisher : Springer Nature
ISBN 13 : 3030352064
Total Pages : 432 pages
Book Rating : 4.0/5 (33 download)
Download or read book Neuroimaging in Schizophrenia written by Marek Kubicki and published by Springer Nature. This book was released on 2020-02-18 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive book explains the importance of imaging techniques in exploring and understanding the role of brain abnormalities in schizophrenia. The findings obtained using individual imaging modalities and their biological interpretation are reviewed in detail, and updates are provided on methodology, testable hypotheses, limitations, and new directions for research. The coverage also includes important recent applications of neuroimaging to schizophrenia, for example in relation to non-pharmacological interventions, brain development, genetics, and prediction of treatment response and outcome. Written by world renowned experts in the field, the book will be invaluable to all who wish to learn about the newest and most important developments in neuroimaging research in schizophrenia, how these developments relate to the last 30 years of research, and how they can be leveraged to bring us closer to a cure for this devastating disorder. Neuroimaging in Schizophrenia will assist clinicians in navigating what is an extremely complex field and will be a source of insight and stimulation for researchers.
Author : Cynthia H. Y. Fu
Publisher : CRC Press
ISBN 13 : 9781841842295
Total Pages : 288 pages
Book Rating : 4.8/5 (422 download)
Download or read book Neuroimaging in Psychiatry written by Cynthia H. Y. Fu and published by CRC Press. This book was released on 2003-09-26 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: New neuroimaging techniques are developing at a break neck pace-every academic journal contains glossy pictures of brain activity corresponding to a particular task emblazoned in glorious technicolor. Discoveries about brain function in psychiatric disorders have been made at an equally rapid rate. However, most books on the subject have been written from a technical point of view. An introductory, easy-to-read guide, Neuroimaging in Psychiatry provides an overview and the clinical relevance of the latest neuroimaging findings. With contributions from an international panel of experts, this book reviews current findings from neuroimaging in schizophrenia, obsessive-compulsive disorder, depression, eating disorders, psychopathy, aging, and drug addiction. Chapter authors explore innovative and imaginative uses of neuro imaging technology, implications for our understanding of these disorders, and their impact on clinical practice. The book gives you a general overview of the main techniques to help you successfully complete a neuroimaging project.
Author : Chris Turck
Publisher : Springer
ISBN 13 : 9780387570853
Total Pages : 538 pages
Book Rating : 4.5/5 (78 download)
Download or read book Biomarkers for Psychiatric Disorders written by Chris Turck and published by Springer. This book was released on 2010-11-16 with total page 538 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomarkers hold immense promise for the early detection of disease. Unlike other disorders like diabetes and heart disease where a limited number of biological markers are at hand that allow the physician to come up with a reliable diagnosis, there are currently no such markers available for affective disorders. As in any other disease area a major goal is therefore the identification of early markers that can categorize subsets of subjects in a consistent manner. This will allow a more precise definition and categorization of affective disorders and in turn facilitate investigations of the pathogenesis of the diseases and enhance our ability for treatment. This edited volume will not only address the area of affective disorders but also other brain disorders that are neurological in nature, including Multiple Sclerosis and Alzheimer Disease.
Author : Daniel Barron
Publisher :
ISBN 13 : 9781734420784
Total Pages : pages
Book Rating : 4.4/5 (27 download)
Download or read book Reading Our Minds written by Daniel Barron and published by . This book was released on 2021-05-11 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309178282
Total Pages : 128 pages
Book Rating : 4.3/5 (91 download)
Download or read book Neuroscience Biomarkers and Biosignatures written by Institute of Medicine and published by National Academies Press. This book was released on 2008-01-08 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomarkers, or biological markers, are quantitative measurements that offer researchers and clinicians valuable insight into diagnosis, treatment and prognosis for many disorders and diseases. A major goal in neuroscience medical research is establishing biomarkers for disorders of the nervous system. Given the promising potential and necessity for neuroscience biomarkers, the Institute of Medicine Forum on Neuroscience and Nervous System Disorders convened a public workshop and released the workshop summary entitled Neuroscience Biomarkers and Biosignatures: Converging Technologies, Emerging Partnerships. The workshop brought together experts from multiple areas to discuss the most promising and practical arenas in neuroscience in which biomarkers will have the greatest impact. The main objective of the workshop was to identify and discuss biomarker targets that are not currently being aggressively pursued but that could have the greatest near-term impact on the rate at which new treatments are brought forward for psychiatric and neurological disorders.
Author : Michael Berk
Publisher : Springer Nature
ISBN 13 : 303071229X
Total Pages : 438 pages
Book Rating : 4.0/5 (37 download)
Download or read book Immuno-Psychiatry written by Michael Berk and published by Springer Nature. This book was released on 2021-08-14 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a thorough and critical review of current knowledge on the role of immunology in major psychiatric disorders and its potential applications. The opening chapters offer general information on the immune influence of the brain to provide readers with a better understanding of the end of immune privilege. The book then examines possible underlying mechanisms leading to psychiatric disorders, from early infections to pro-inflammatory markers, stress, and immune genetic background, linking etiology and psychiatry. The third section describes each disorder (ie autism, schizophrenia, bipolar disorder, depression...) with an overview of underlying immune dysfunctions. Lastly, the authors discuss the innovative immune-therapies that may result from the discovery of immune system biomarkers and their associated mechanisms. A better understanding of the role of the immune system in psychiatric disorders makes it possible to identify stratification biomarkers, to explain underlying mechanisms, and to develop innovative, efficient, targeted treatment strategies and management. As such, the book is of value to clinicians, mental health professionals, mental health researchers, immunologists, industry practitioners, and various stakeholders in the mental health field.
