The Chemistry and Biology of Nitroxyl (HNO)

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Publisher : Elsevier
ISBN 13 : 0128011645
Total Pages : 425 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis The Chemistry and Biology of Nitroxyl (HNO) by : Fabio Doctorovich

Download or read book The Chemistry and Biology of Nitroxyl (HNO) written by Fabio Doctorovich and published by Elsevier. This book was released on 2016-09-01 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Chemistry and Biology of Nitroxyl (HNO) provides first-of-its-kind coverage of the intriguing biologically active molecule called nitroxyl, or azanone per IUPAC nomenclature, which has been traditionally elusive due to its intrinsically high reactivity. This useful resource provides the scientific basis to understand the chemistry, biology, and technical aspects needed to deal with HNO. Building on two decades of nitric oxide and nitroxyl research, the editors and authors have created an indispensable guide for investigators across a wide variety of areas of chemistry (inorganic, organic, organometallic, biochemistry, physical, and analytical); biology (molecular, cellular, physiological, and enzymology); pharmacy; and medicine. This book begins by exploring the unique molecule's structure and reactivity, including important reactions with small molecules, thiols, porphyrins, and key proteins, before discussing chemical and biological sources of nitroxyl. Advanced chapters discuss methods for both trapping and detecting nitroxyl by spectroscopy, electrochemistry, and fluorescent inorganic cellular probing. Expanding on the compound's foundational chemistry, this book then explores its molecular physiology to offer insight into its biological implications, pharmacological effects, and practical issues. - Presents the first book on HNO (nitroxyl or azanone), an increasingly important molecule in biochemistry and pharmaceutical research - Provides a valuable coverage of HNO's chemical structure and significant reactions, including practical guidance on working with this highly reactive molecule - Contains high quality content from recognized experts in both industry and academia

Dissertation Abstracts International

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Publisher :
ISBN 13 :
Total Pages : 800 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Dissertation Abstracts International by :

Download or read book Dissertation Abstracts International written by and published by . This book was released on 2008 with total page 800 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Methods in Nitric Oxide Research

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Publisher :
ISBN 13 :
Total Pages : 746 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis Methods in Nitric Oxide Research by : Martin Feelisch

Download or read book Methods in Nitric Oxide Research written by Martin Feelisch and published by . This book was released on 1996-06-04 with total page 746 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook describes methods for the measurement and investigation of nitric oxide. The topics discussed include the metabolism of substrates and cofactors, the detection of nitrogen oxides, the detection of nitrogen oxide synthase activity, and the detection of adducts and reaction products.

In Vivo EPR (ESR)

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Publisher : Springer Science & Business Media
ISBN 13 : 1461500613
Total Pages : 670 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis In Vivo EPR (ESR) by : Lawrence J. Berliner

Download or read book In Vivo EPR (ESR) written by Lawrence J. Berliner and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 670 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Vivo EPR (ESR) is a textbook on this relatively new subject in biomedical electron spin resonance. While a few chapters have appeared in special topics volumes in this series, this book covers the principles and theory, instrumentation as well as the latest applications at the time of its writing. The authors are world-renowned experts and pioneers in their fields. This book is divided into two major sections dealing with theory and instrumentation, and aspects of biochemistry, in vitro and in vivo applications. A significant amount of detail is devoted to clinical applications and the problems and pitfalls encountered in in vivo spectroscopy and imaging. Key Features: -History of In Vivo EPR, -Principles of Imaging-Theory and Instrumentation, -Time-domain Radio Frequency EPR Imaging, -The Measurement of Oxygen In Vivo Using In Vivo EPR Techniques, -Potential Medical (Clinical) Applications of EPR, -Combining NMR and EPR/ESR for In Vivo Experiments.

Measuring Oxidants and Oxidative Stress in Biological Systems

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Publisher : Springer Nature
ISBN 13 : 303047318X
Total Pages : 237 pages
Book Rating : 4.0/5 (34 download)

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Book Synopsis Measuring Oxidants and Oxidative Stress in Biological Systems by : Lawrence J. Berliner

Download or read book Measuring Oxidants and Oxidative Stress in Biological Systems written by Lawrence J. Berliner and published by Springer Nature. This book was released on 2020-08-08 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the methods of analysis and determination of oxidants and oxidative stress in biological systems. Reviews and protocols on select methods of analysis of ROS, RNS, oxygen, redox status, and oxidative stress in biological systems are described in detail. It is an essential resource for both novices and experts in the field of oxidant and oxidative stress biology.

Metal Nitrosyls

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Publisher : Oxford University Press, USA
ISBN 13 : 9780195067934
Total Pages : 369 pages
Book Rating : 4.0/5 (679 download)

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Book Synopsis Metal Nitrosyls by : George B. Richter-Addo

Download or read book Metal Nitrosyls written by George B. Richter-Addo and published by Oxford University Press, USA. This book was released on 1992 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers all aspects of metal-nitric oxide chemistry. Topics range from descriptions of the metal-NO bond to their chemical reactions and environmental significance. Treated in detail are coordination and organometallic nitrosyl complexes, interactions of nitric oxide with surfaces, metal nitrosyl clusters and the biosynthesis, biotransformation, and bioinorganic chemistry of nitric oxide. The book includes an examination of all known classes of reactions of metal nitrosyls. The roles of nitric and nitrous oxides in environmental chemistry are outlined in the closing chapter. This book will be of interest to students and researchers in the fields of inorganic, organometallic, and bioinorganic chemistry.

Nitrosation Reactions and the Chemistry of Nitric Oxide

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Author :
Publisher : Elsevier
ISBN 13 : 0080473601
Total Pages : 281 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Nitrosation Reactions and the Chemistry of Nitric Oxide by : D.L.H. Williams

Download or read book Nitrosation Reactions and the Chemistry of Nitric Oxide written by D.L.H. Williams and published by Elsevier. This book was released on 2004-12-16 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since 1988, there has been much literature published on the chemistry of nitric oxide, particularly in the field of S-nitrosation and the chemistry of S-nitroso compounds. Written by a chemist for the chemistry community, this book provides an update of the chemistry of nitrosation reactions, dealing with both the synthetic and mechanistic aspects of these reactions. It also looks at the chemistry of nitric oxide in relation to the amazing biological properties of this simple diatomic molecule, which were unknown until around 1990.* Provides an update on previously published literature on nitric oxide chemistry* Contains chapters on reagents for nitrosation, nitrosation at nitrogen, aliphatic and aromatic carbon, oxygen, sulfur and metal centres* Looks at hot research topics such as synthesis, properties and reactions of s-nitrosothiols

Nitric Oxide

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Author :
Publisher : Academic Press
ISBN 13 : 0128043199
Total Pages : 436 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Nitric Oxide by : Louis J. Ignarro

Download or read book Nitric Oxide written by Louis J. Ignarro and published by Academic Press. This book was released on 2017-07-24 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nitric Oxide: Biology and Pathobiology, Third Edition, provides information on nitric oxide, a signaling molecule of key importance for the cardiovascular system that regulates blood pressure and blood flow to different organs. With recent links to the role of nitric oxide in the expression of healthy benefits of controlled diet and aerobic exercise, and the reactions of nitric oxide that can impact cell signaling, this book provides a comprehensive resource during a time when increased research attention is being paid across the fields of pharmacology, biochemistry, cell and molecular biology, chemistry, immunology, neurobiology, immunology, nutrition sciences, drug development and the clinical management of both acute and chronic diseases. - Includes perspectives from Jack Lancaster on the discovery of EDRF and nitric oxide - Provides detailed coverage of the new gaseous signaling agents - Features expanded coverage on the principles of biology, including nitric oxide synthases, nitrite and nitrate biology and pathobiology, and signaling mechanisms - Incorporates expanded pathobiology coverage, including nitric oxide and cardiovascular function, obesity, diabetes, and erectile function/dysfunction

Peroxynitrite Detection in Biological Media

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Publisher : Royal Society of Chemistry
ISBN 13 : 1782620850
Total Pages : 250 pages
Book Rating : 4.7/5 (826 download)

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Book Synopsis Peroxynitrite Detection in Biological Media by : Sabine Szunerits

Download or read book Peroxynitrite Detection in Biological Media written by Sabine Szunerits and published by Royal Society of Chemistry. This book was released on 2015-10-21 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: Peroxynitrite detection and quantification provides critical information in understanding its biological implications. It will be welcomed by the community particularly medicinal and analytical chemists, developers of sensors and probes and analytical equipment manufacturers.

Aromatic C-nitroso Compounds

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Publisher : Springer Science & Business Media
ISBN 13 : 9400763379
Total Pages : 168 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Aromatic C-nitroso Compounds by : Hrvoj Vančik

Download or read book Aromatic C-nitroso Compounds written by Hrvoj Vančik and published by Springer Science & Business Media. This book was released on 2013-03-12 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is designed to collect and review the research covering main directions in investigations of aromatic nitroso compounds in last decades, and to present both, the academic aspects of this chemistry, as well as the open field of its applicability. The book is divided in five chapters. The basic structural properties of the nitroso aromatic molecules are described in the first chapter. The second chapter is an overview of the methods of preparations of aromatic nitroso and polynitroso compounds, including classical synthetic methods and some new preparative approaches. The third part deals with the physico-chemical properties of nitroso aromates and azodioxides, its structure, crystallography, quantum chemical calculations, spectroscopy, typical reactions, and especially it is focused on the dimerizations in the solid-state. In the fourth chapter is represented organometallic chemistry of nitroso aromatic molecules and its applications in catalysis. The last part of the book deals with the behavior of this class of compounds in the biological systems, reactions with biomolecules and the use in toxicology.

Handbook of Antioxidants

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Publisher : CRC Press
ISBN 13 : 0824745108
Total Pages : 732 pages
Book Rating : 4.8/5 (247 download)

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Book Synopsis Handbook of Antioxidants by : Lester Packer

Download or read book Handbook of Antioxidants written by Lester Packer and published by CRC Press. This book was released on 2001-10-26 with total page 732 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contains new and expanded material on antioxidants in beverages and herbal products, nitric oxide and selenium, and the effect of vitamin C on cardiovascular disease and of lipoic acid on aging, hyperglycemia, and insulin resistance! Offering over 4200 contemporary references-2000 more than the previous edition-the Second Edition of the Handbook of Antioxidants is an up-to-the-minute source for nutritionists and dietitians, cell biologists and biochemists, cardiologists, oncologists, dermatologists, and medical students in these disciplines.

Advanced Concepts in Fluorescence Sensing

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Publisher : Springer Science & Business Media
ISBN 13 : 0387233350
Total Pages : 333 pages
Book Rating : 4.3/5 (872 download)

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Book Synopsis Advanced Concepts in Fluorescence Sensing by : Chris D. Geddes

Download or read book Advanced Concepts in Fluorescence Sensing written by Chris D. Geddes and published by Springer Science & Business Media. This book was released on 2007-05-24 with total page 333 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last decade, fluorescence has become the dominant tool in biotechnology and medical imaging. These exciting advances have been underpinned by the advances in time-resolved techniques and instrumentation, probe design, chemical / biochemical sensing, coupled with our furthered knowledge in biology. Complementary volumes 9 and 10, Advanced Concepts of Fluorescence Sensing: Small Molecule Sensing and Advanced Concepts of Fluorescence Sensing: Macromolecular Sensing, aim to summarize the current state of the art in fluorescent sensing. For this reason, Drs. Geddes and Lakowicz have invited chapters, encompassing a broad range of fluorescence sensing techniques. Some chapters deal with small molecule sensors, such as for anions, cations, and CO2, while others summarize recent advances in protein-based and macromolecular sensors. The Editors have, however, not included DNA or RNA based sensing in this volume, as this were reviewed in Volume 7 and is to be the subject of a more detailed volume in the near future.

Free Radicals, Nitric Oxide, and Inflammation

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Author :
Publisher : IOS Press
ISBN 13 : 9781586032432
Total Pages : 268 pages
Book Rating : 4.0/5 (324 download)

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Book Synopsis Free Radicals, Nitric Oxide, and Inflammation by : Tomris Özben

Download or read book Free Radicals, Nitric Oxide, and Inflammation written by Tomris Özben and published by IOS Press. This book was released on 2003 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Journal

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Publisher :
ISBN 13 :
Total Pages : 1042 pages
Book Rating : 4.:/5 (334 download)

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Book Synopsis Journal by : American Chemical Society

Download or read book Journal written by American Chemical Society and published by . This book was released on 2004 with total page 1042 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Metal Transporters

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Publisher : Academic Press
ISBN 13 : 0123943906
Total Pages : 478 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Metal Transporters by : Jose M. Arguello

Download or read book Metal Transporters written by Jose M. Arguello and published by Academic Press. This book was released on 2012-10-25 with total page 478 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of Current Topics in Membranes focuses on metal transmembrane transporters and pumps, a recently discovered family of membrane proteins with many important roles in the physiology of living organisms. The book summarizes the most recent advances in the field of metal ion transport and provides a broad overview of the major classes of transporters involved in homeostasis of heavy metals. Various families of the transporters and metal specificities are discussed with the focus on the structural and mechanistic aspects of their function and regulation. The reader will access information obtained through a variety of approaches ranging from X-ray crystallography to cell biology and bioinformatics, which have been applied to transporters identified in diverse biological systems, such as pathogenic bacteria, plants, humans and others. Field is cutting-edge and a lot of the information is new to research community Wide breadth of topic coverage Contributors of high renown and expertise

Radicals for Life

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Publisher : Elsevier
ISBN 13 : 0080489591
Total Pages : 444 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Radicals for Life by : Ernst van Faassen

Download or read book Radicals for Life written by Ernst van Faassen and published by Elsevier. This book was released on 2011-10-13 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radicals for Life: the Various Forms of Nitric Oxide provides an up-to-date overview of the role of nitrosocompounds and nitrosyl-iron complexes in physiology. Nitrosocompounds can be considered as stabilised forms of nitric oxide, one of the most important regulatory molecules in physiology today. Many nitrosocompounds share some of the physiological functions of nitric oxide, and may be formed inside living organisms. This is the first book to be published that is dedicated to the role of such nitrosocompounds in physiology, with particular emphasis on the nitrosocompounds that are endogenously formed in higher organisms and humans. Points of discussion include: physical and chemical properties of the compounds, the main chemical pathways in vivo, as well as the physiological effects that have been recognised to date. Each of the nineteen chapters is written by distinguished specialists in the field, well known for their original and important contributions to the subject. Also included are results from a wide range of studies in vitro, in cell cultures, animal models and human volunteers. Examples of alternative forms of nitric oxide, with special emphasis on their protective role against widespread human diseases like atherosclerosis, Alzheimer's disease, diabetes, sexual dysfunction, and renal insufficiency to stroke and ischemia are also included. - First monograph to consider and provide an overview of endogenous nitrosocompounds and nitrosyl-iron complexes - Extensive bibliographic references, written by specialists of human physiology - Providing high scientific quality with a focus on implications for human diseases

Bio-Assays for Oxidative Stress Status

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Publisher : Elsevier
ISBN 13 : 0080929923
Total Pages : 297 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Bio-Assays for Oxidative Stress Status by : W.A. Pryor

Download or read book Bio-Assays for Oxidative Stress Status written by W.A. Pryor and published by Elsevier. This book was released on 2012-12-02 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work contains over thirty chapters by leading researchers in the field of oxidative biology, originally presented as articles in an extended Forum in the highly-cited journal, Free Radical Biology & Medicine. The papers in this Forum (or Symposium-in-print) spanned seven issues of the journal, over many months. This is the first time that all of these expert contributions are presented in one place.Reliable methods for measuring OSS in organisms are essential. These would, amongst other things, offer applications as early warning signals for cancer and heart disease - eventually giving a range of measurable oxidation products best related to any given disease state.Additional observations relevant to OSS include: how much do measures of OSS vary in a group of humans? Does OSS decrease as a result of life-change factors and does it increase with age? With disease? With stress? Can a non-invasive, reliable, reputable measure of OSS be identified?This informative book provides the reader with the latest status of studies into OSS, currently used examples of BOSS, and answers to at least some of the questions posed above.