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Author : Louis M. Aledort
Publisher :
ISBN 13 :
Total Pages : 640 pages
Book Rating : 4.3/5 (91 download)
Download or read book The Circulating Platelet written by Louis M. Aledort and published by . This book was released on 1971 with total page 640 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Shirley A. Johnson
Publisher : Elsevier
ISBN 13 : 0323144322
Total Pages : 623 pages
Book Rating : 4.3/5 (231 download)
Download or read book The Circulating Platelet written by Shirley A. Johnson and published by Elsevier. This book was released on 2012-12-02 with total page 623 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Circulating Platelet focuses on the biochemistry and physiology of platelets. Composed of contributions of authors, the compilation starts with the discussions on the origin, discovery, production, and life span of blood platelets. The discussions continue with the morphology of platelets. Concerns include peripheral, sol-gel, and organelle zones and the membrane systems. The book also looks at the energy metabolism of thrombocytes and highlights the presence of glycoproteins in blood platelets. These include polysaccharides, glucosaminoglycans, and glycoproteins. The text also discusses the properties, functions, and the physiological value of thrombosthenin. The compilation further discusses platelet aggregation and functions of platelets. Concerns include collection and processing of platelets; preparation of homogenates; and the agents that influence platelet aggregation. The role of platelets in blood clots and fibrinolysis is emphasized. The selection ends with discussions on the immunological reactions of platelets; the clinical diseases related to blood platelets; and blood transfusion and preservation. The text is vital for researchers interested in studying blood platelets.
Author : Laurenz J. Wurzinger
Publisher : Springer
ISBN 13 :
Total Pages : 116 pages
Book Rating : 4.:/5 (89 download)
Download or read book Histophysiology of the Circulating Platelet written by Laurenz J. Wurzinger and published by Springer. This book was released on 1990-06-29 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt: 1. 1 Platelets in Hemostasis and Thrombosis: A Brief Overview For more than 100 years the dominant role of blood platelets in hemostasis and thrombosis has been well documented. Seven years before their identification as a distinct class of blood corpuscles by Bizzozero (1882), Zahn (1875), using intravital microscopic observations, described the growth of an arterial thrombus as the result of "continued apposition of colorless blood corpuscles along the direction of blood flow. " A hallmark still valid today was set by Eberth and Schimmel busch (1888), who clearly divided the formation of the hemostatic plug into the result of the "conglutination of preformed blood corpuscles," followed by the "plasmatic coagulation as the formation of fibrin from substances dissolved in blood," as two distinct processes taking place in the described order. In spite of technical shortcomings, by approaching the limits of the light microscopic techniques of their time, Eberth and Schimmel busch discovered a change in the morphology of the platelets, paralleled by a presumptive change in their functional state, which was a prerequisite for the formation of a platelet plug. Their meticulous description implicitly anticipated the modern terminology of the "smooth disk" as the resting form of the circulating platelet and the activated "spiny sphere" as a result of a change in shape following stimulation.
Author : Beth H. Shaz
Publisher : Newnes
ISBN 13 : 0123977886
Total Pages : 1015 pages
Book Rating : 4.1/5 (239 download)
Download or read book Transfusion Medicine and Hemostasis written by Beth H. Shaz and published by Newnes. This book was released on 2013-05-13 with total page 1015 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of Transfusion Medicine and Hemostasis continues to be the only "pocket-size" quick reference for pathology residents and transfusion medicine fellows. It covers all topics in blood banking, transfusion medicine, and clinical and laboratory based coagulation. Short, focused chapters, organized by multiple hierarchical headings, are supplemented with up to 10 suggested reading citations. This single reference covers essentially all the topics required to meet the goals and objectives of a major program in transfusion medicine and clinical coagulation. New chapters in the coagulation testing section reflect the development of new tests available and their incorporation into clinical practice. Coverage includes essential updates on the importance of new cellular therapies, peripheral blood and bone marrow hematopoietic progenitor cells, as well as cord blood banking and regenerative medicine. The authors also examine advances in the understanding of molecular testing and pathogen reduction in two separate quality control chapters (one for blood centers and one for hospitals). Updated content covers new coagulation tests, cellular therapies, and quality control issues Easy to use, with focused, well-defined chapters in a standardized format throughout Offers quick "cross-reference" lists at the end of each chapter Includes lists of common abbreviations and indexes that cross reference diagnostic, clinical and therapeutic commonalities
Author : John Martin
Publisher : Springer Science & Business Media
ISBN 13 : 1447117638
Total Pages : 276 pages
Book Rating : 4.4/5 (471 download)
Download or read book Platelet Heterogeneity written by John Martin and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: Battle is a practical and sometimes lasting way of solving man's problems. It relies on the strength of the combatants and ignores the truth of the dispute. Discussion face to face can dissolve attitudes which have incorrectly determined judgements. The most striking example of this that I know is a Battle in Ireland in the eleventh century, where the king of Leinster fought a Viking prince. The Icelanders had raided Ireland for several generations in search of women, which they lacked since most of the population of Iceland were men who had arrived there by rowing long-boats from Norway. The prince was leading such a raid for the first time. Standing in the prow of the leading boat he saw Irish cavalry galloping along the beach to meet them. As they approached the shore the Irish king rode out of the band to challenge single combat. The Icelander jumped into the surf to meet him. As they raised their swords each realized that the other's face was like his own. When the Irish king spoke the other recognized the language. It had been spoken in Iceland by his grandmother who had been captured and taken there from Ireland. Swords were dropped and replaced by drinking horns. It was soon established that they were cousins. The battle gave way to a life-time of close co-operation.
Author : Jonathan M. Gibbins
Publisher : Humana Press
ISBN 13 : 9781617373053
Total Pages : 504 pages
Book Rating : 4.3/5 (73 download)
Download or read book Platelets and Megakaryocytes written by Jonathan M. Gibbins and published by Humana Press. This book was released on 2010-11-10 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: 12 The average human body has on the order of 10 circulating platelets. They are crucial for hemostasis, and yet excessive platelet activation is a major cause of m- bidity and mortality in Western societies. It is therefore not surprising that platelets have become one of the most extensively investigated biological cell types. We are, however, far from understanding precisely how platelets become activated under physiological and pathophysiological conditions. In addition, there are large gaps in our knowledge of platelet production from their giant precursor cell, the megakar- cyte. Understanding megakaryocyte biology will be crucial for the development of platelet gene targeting. The aim of Platelets and Megakaryocytes is therefore to bring together established and recently developed techniques to provide a comprehensive guide to the study of both the platelet and the megakaryocyte. It consists of five s- tions split between two volumes. The more functional assays appear in Volume 1, whereas Volume 2 includes signaling techniques, postgenomic methods, and a n- ber of key perspectives chapters. Part I of Volume 1, Platelets and Megakaryocytes: Functional Assays, describes many well-established approaches to the study of platelet function, including aggregometry, secretion, arachidonic acid metabolism, procoagulant responses, pla- let adhesion under static or flow conditions, flow cytometry, and production of microparticles. Although one would ideally wish to perform experiments with human platelets, studies within the circulation using intravital microscopy require the use of animal models, which are described in Chapter 16, vol. 1.
Author : Robert Fitridge
Publisher : University of Adelaide Press
ISBN 13 : 1922064009
Total Pages : 589 pages
Book Rating : 4.9/5 (22 download)
Download or read book Mechanisms of Vascular Disease written by Robert Fitridge and published by University of Adelaide Press. This book was released on 2011 with total page 589 pages. Available in PDF, EPUB and Kindle. Book excerpt: New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.
Author : Jonathan M. Gibbins
Publisher : Springer Science & Business Media
ISBN 13 : 1592597823
Total Pages : 389 pages
Book Rating : 4.5/5 (925 download)
Download or read book Platelets and Megakaryocytes written by Jonathan M. Gibbins and published by Springer Science & Business Media. This book was released on 2008-02-04 with total page 389 pages. Available in PDF, EPUB and Kindle. Book excerpt: 12 The average human body has in the order of 10 circulating platelets. They are crucial for hemostasis, and yet excessive platelet activation is a major cause of m- bidity and mortality in western societies. It is therefore not surprising that platelets have become one of the most extensively investigated biological cell types. We are, however, far from understanding precisely how platelets become activated under physiological and pathophysiological conditions. In addition, there are large gaps in our knowledge of platelet production from their giant precursor cell, the megakar- cyte. Understanding megakaryocyte biology will be crucial for the development of platelet gene targeting. The aim of Platelets and Megakaryocytes is therefore to bring together established and recently developed techniques to provide a comprehensive guide to the study of both the platelet and the megakaryocyte. It consists of five s- tions split between two volumes. The more functional assays appear in Volume 1, whereas Volume 2 includes signaling techniques, postgenomic methods, and a n- ber of key perspectives chapters. Part I of Volume 1, Platelets and Megakaryocytes: Functional Assays, describes many well established approaches to the study of platelet function, including aggregometry, secretion, arachidonic acid metabolism, procoagulant responses, pla- let adhesion under static or flow conditions, flow cytometry, and production of microparticles. Although one would ideally wish to perform experiments with human platelets, studies within the circulation using intravital microscopy require the use of animal models, which are described in Chapter 16, vol. 1.
Author : Kenneth Merle Brinkhous
Publisher :
ISBN 13 :
Total Pages : 444 pages
Book Rating : 4.3/5 (91 download)
Download or read book The Platelet written by Kenneth Merle Brinkhous and published by . This book was released on 1971 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Steve W. Kerrigan
Publisher : BoD – Books on Demand
ISBN 13 : 9535122088
Total Pages : 250 pages
Book Rating : 4.5/5 (351 download)
Download or read book The Non-Thrombotic Role of Platelets in Health and Disease written by Steve W. Kerrigan and published by BoD – Books on Demand. This book was released on 2015-11-18 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: Platelets play a key role in thrombosis and haemostasis. However recent evidence clearly demonstrates that the functional role of platelets extends to many other processes in the body. With an internationally recognised list of contributing authors, The Non-Thrombotic Role of Platelets in Health and Disease, is a unique and definitive source of state-of-the-art knowledge about the additional role of platelets outside thrombosis and haemostasis. The intended audience for The Non-Thrombotic Role of Platelets in Health and Disease includes platelet biologists, microbiologists, immunologists, haematologists, oncologists, respiratory physicians, cardiologists, neurobiologists, tissue engineers, as well as students and fellows in these areas.
Author : Christoff Kessler
Publisher : Springer
ISBN 13 :
Total Pages : 132 pages
Book Rating : 4.3/5 (91 download)
Download or read book Platelets and Atherosclerosis written by Christoff Kessler and published by Springer. This book was released on 1991 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most patients with cerebrovascular diseases are treated with antiplatelet drugs. Basic thromosis research showed that platelets are an important factor in the pathogenesis of ar- therosclerosis and its complications, but other compounds as macrophages and vessel wall factors are also involved in this process. The aim of this volume is to connect labora- tory findings with clinical applications.
Author : Robert S. Hillman
Publisher : McGraw Hill Professional
ISBN 13 : 0071766537
Total Pages : 512 pages
Book Rating : 4.0/5 (717 download)
Download or read book Hematology in Clinical Practice, Fifth Edition written by Robert S. Hillman and published by McGraw Hill Professional. This book was released on 2010-10-22 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: The most practical and efficient guide to the diagnosis and management of blood disorders – now in full color 200 full-color illustrations! Hematology in Clinical Practice is a succinct, cutting-edge guide to the diagnosis and treatment of disorders of red blood cells, white blood cells, and hemostasis, and the use of blood components for transfusion. Each disease state is discussed in detail, incorporating the pathophysiology, clinical features, up-to-date laboratory testing, and current management strategies into a comprehensive and practical approach to hematologic disorders. Features: New full-color presentation includes over 200 superb illustrations and classic images of blood morphology, tissue pathology, and clinical findings New Case Histories introduce and continue through relevant chapters, highlighting critical clinical points for diagnosis and management New end-of-chapter Points to Remember encapsulate key clinical information New chapters include Anemia in the Elderly and expanded and updated coverage of Transplantation and treatment of hematologic malignancies Outstanding collection of tables, charts, and illustrations that translate basic science into valuable clinical context Strong focus on practical clinical management and supportive care Coverage of state-of-the-art drugs and chemotherapies and the latest advances in genetic testing and molecular pathways Conveniently organized into sections on Red Cells, White Cells, Hemostasis, and Transfusion Medicine
Author : Richard H. Aster
Publisher :
ISBN 13 :
Total Pages : 388 pages
Book Rating : 4.3/5 (91 download)
Download or read book Platelet Kinetics written by Richard H. Aster and published by . This book was released on 1971 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Paolo Gresele
Publisher : Springer
ISBN 13 : 3319474626
Total Pages : 1402 pages
Book Rating : 4.3/5 (194 download)
Download or read book Platelets in Thrombotic and Non-Thrombotic Disorders written by Paolo Gresele and published by Springer. This book was released on 2017-03-08 with total page 1402 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews current science and applications in fields including thrombosis and hemostasis, signal transduction, and non-thrombotic conditions such as inflammation, allergy and tumor metastasis. It is a detailed, up-to-date, highly referenced text for clinical scientists and physicians, including recent developments in this rapidly expanding field. More than a scientific resource, this is also an authoritative reference and guide to the diagnosis.
Author : Pedro A. de Alarcón
Publisher : Cambridge University Press
ISBN 13 : 1108488986
Total Pages : 501 pages
Book Rating : 4.1/5 (84 download)
Download or read book Neonatal Hematology written by Pedro A. de Alarcón and published by Cambridge University Press. This book was released on 2021-02-18 with total page 501 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential guide to the pathogenesis, diagnosis and management of hematologic problems in the neonate, covering erythrocyte disorders, leukocyte disorders, immunologic disorders and hemostatic disorders. Guidance is practical, including blood test interpretation, advice on transfusions and reference ranges for hematological values.
Author : Alex S. Evers
Publisher : Cambridge University Press
ISBN 13 : 1139497022
Total Pages : 2902 pages
Book Rating : 4.1/5 (394 download)
Download or read book Anesthetic Pharmacology written by Alex S. Evers and published by Cambridge University Press. This book was released on 2011-03-10 with total page 2902 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years our understanding of molecular mechanisms of drug action and interindividual variability in drug response has grown enormously. Meanwhile, the practice of anesthesiology has expanded to the preoperative environment and numerous locations outside the OR. Anesthetic Pharmacology: Basic Principles and Clinical Practice, 2nd edition, is an outstanding therapeutic resource in anesthesia and critical care: Section 1 introduces the principles of drug action, Section 2 presents the molecular, cellular and integrated physiology of the target organ/functional system and Section 3 reviews the pharmacology and toxicology of anesthetic drugs. The new Section 4, Therapeutics of Clinical Practice, provides integrated and comparative pharmacology and the practical application of drugs in daily clinical practice. Edited by three highly acclaimed academic anesthetic pharmacologists, with contributions from an international team of experts, and illustrated in full colour, this is a sophisticated, user-friendly resource for all practitioners providing care in the perioperative period.
Author : Alan D. Michelson
Publisher : Academic Press
ISBN 13 : 0123878373
Total Pages : 1399 pages
Book Rating : 4.1/5 (238 download)
Download or read book Platelets written by Alan D. Michelson and published by Academic Press. This book was released on 2013-01-09 with total page 1399 pages. Available in PDF, EPUB and Kindle. Book excerpt: Platelets - winner of a 2013 Highly Commended BMA Medical Book Award for Internal Medicine - is the definitive current source of state-of-the-art knowledge about platelets and covers the entire field of platelet biology, pathophysiology, and clinical medicine. Recently there has been a rapid expansion of knowledge in both basic biology and the clinical approach to platelet-related diseases including thrombosis and hemorrhage. Novel platelet function tests, drugs, blood bank storage methods, and gene therapies have been incorporated into patient care or are in development. This book draws all this information into a single, comprehensive and authoritative resource. Highly Commended BMA Medical Book Award 2013: Internal Medicine Comprehensive and definitive source of knowledge about platelets for clinicians, pathologists and scientists Integrates the entire field of platelet biology, pathophysiology, and clinical medicine Full color reference comprising 64 chapters, 1400 pages, and 16,000 references Contributions from 126 world leaders in their fields New chapters on topics such as the regulation of platelet life span, platelet microRNAs, GPVI and CLEC-2, monitoring of antiplatelet therapy, novel antiplatelet therapy, and making platelets ex vivo
