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Author : William F. Fleet (III)
Publisher :
ISBN 13 :
Total Pages : 102 pages
Book Rating : 4.:/5 (948 download)
Download or read book The Chemistry of Reduced Copper Complexes of Bis(thiosemicarbazones) written by William F. Fleet (III) and published by . This book was released on 1981 with total page 102 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Kazuo Nakamoto
Publisher : John Wiley & Sons
ISBN 13 :
Total Pages : 384 pages
Book Rating : 4.3/5 (91 download)
Download or read book Infrared Spectra of Inorganic and Coordination Compounds written by Kazuo Nakamoto and published by John Wiley & Sons. This book was released on 1970 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Marina A. Zenkova
Publisher : Springer Science & Business Media
ISBN 13 : 9783540201120
Total Pages : 330 pages
Book Rating : 4.2/5 (11 download)
Download or read book Artificial Nucleases written by Marina A. Zenkova and published by Springer Science & Business Media. This book was released on 2004-01-07 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: The development of agents capable of cleaving RNA and DNA has attracted considerable attention from researchers in the last few years, because of the immediate and very important applications they can find in the emerging fields of biotechnology and pharmacology. There are essentially two classes of these agents - nucleases that occur naturally inside cells and synthetically produced artificial nucleases. The first class includes protein enzyme nucle ases and catalytic RNA structured ribozymes that perform cleavage of the phosphodiester bonds in nucleic acids according to a hydrolytic pathway in the course of different biochemical processes in the cell. A different pathway is used by some antibiotics which cleave DNA via redox-based mechanisms resulting in oxidative damage of nucleotide units and breakage of the DNA backbone. The above molecules are indispensable tools for manipulating nucleic acids and processing RNA; DNA-cleaving antibiotics and cytotoxic ribonucleases have demonstrated utility as chemotherapeutic agents. The second class, artificial nucleases, are rationally designed to imitate the active centers of natural enzymes by simple structures possessing minimal sets of the most important characteristics that are essential for catalysis. A dif ferent approach, in vitro selection, was also used to create artificial RNA and DNA enzymes capable of cleaving RNA. Being less efficient and specific as compared to the natural enzymes, the primitive mimics are smaller and robust and can function in a broad range of conditions.
Author : Jacqueline Krejci
Publisher :
ISBN 13 :
Total Pages : 186 pages
Book Rating : 4.:/5 (277 download)
Download or read book Heterocyclic Thiosemicarbazones and Their Copper (II) Complexes written by Jacqueline Krejci and published by . This book was released on 1992 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Mark O. Seidlitz
Publisher :
ISBN 13 :
Total Pages : 96 pages
Book Rating : 4.:/5 (23 download)
Download or read book The Chemistry of Copper (II) Complexes written by Mark O. Seidlitz and published by . This book was released on 1990 with total page 96 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Shahid Ul-Islam
Publisher : John Wiley & Sons
ISBN 13 : 1119640423
Total Pages : 432 pages
Book Rating : 4.1/5 (196 download)
Download or read book Advances in Metallodrugs written by Shahid Ul-Islam and published by John Wiley & Sons. This book was released on 2020-07-08 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is organized into 12 important chapters that focus on the progress made by metal-based drugs as anticancer, antibacterial, antiviral, anti-inflammatory, and anti-neurodegenerative agents, as well as highlights the application areas of newly discovered metallodrugs. It can prove beneficial for researchers, investigators and scientists whose work involves inorganic and coordination chemistry, medical science, pharmacy, biotechnology and biomedical engineering.
Author :
Publisher : ScholarlyEditions
ISBN 13 : 1481692275
Total Pages : 40 pages
Book Rating : 4.4/5 (816 download)
Download or read book Semicarbazones—Advances in Research and Application: 2013 Edition written by and published by ScholarlyEditions. This book was released on 2013-06-21 with total page 40 pages. Available in PDF, EPUB and Kindle. Book excerpt: Semicarbazones—Advances in Research and Application: 2013 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about ZZZAdditional Research in a concise format. The editors have built Semicarbazones—Advances in Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about ZZZAdditional Research in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Semicarbazones—Advances in Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Author : Tim Storr
Publisher : John Wiley & Sons
ISBN 13 : 1118697898
Total Pages : 650 pages
Book Rating : 4.1/5 (186 download)
Download or read book Ligand Design in Medicinal Inorganic Chemistry written by Tim Storr and published by John Wiley & Sons. This book was released on 2014-06-12 with total page 650 pages. Available in PDF, EPUB and Kindle. Book excerpt: Increasing the potency of therapeutic compounds, while limiting side-effects, is a common goal in medicinal chemistry. Ligands that effectively bind metal ions and also include specific features to enhance targeting, reporting, and overall efficacy are driving innovation in areas of disease diagnosis and therapy. Ligand Design in Medicinal Inorganic Chemistry presents the state-of-the-art in ligand design for medicinal inorganic chemistry applications. Each individual chapter describes and explores the application of compounds that either target a disease site, or are activated by a disease-specific biological process. Ligand design is discussed in the following areas: Platinum, Ruthenium, and Gold-containing anticancer agents Emissive metal-based optical probes Metal-based antimalarial agents Metal overload disorders Modulation of metal-protein interactions in neurodegenerative diseases Photoactivatable metal complexes and their use in biology and medicine Radiodiagnostic agents and Magnetic Resonance Imaging (MRI) agents Carbohydrate-containing ligands and Schiff-base ligands in Medicinal Inorganic Chemistry Metalloprotein inhibitors Ligand Design in Medicinal Inorganic Chemistry provides graduate students, industrial chemists and academic researchers with a launching pad for new research in medicinal chemistry.
Author : Nicholas P Farrell
Publisher : Royal Society of Chemistry
ISBN 13 : 1847552242
Total Pages : 174 pages
Book Rating : 4.8/5 (475 download)
Download or read book Uses of Inorganic Chemistry in Medicine written by Nicholas P Farrell and published by Royal Society of Chemistry. This book was released on 2007-10-31 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metal-based drugs are a commercially important sector of the pharmaceutical business, yet most bioinorganic textbooks lack the space to cover comprehensively the subject of metals in medicine. Uses of Inorganic Chemistry in Medicine approaches an understanding of the topic in a didactic and systematic manner. The field of inorganic chemistry in medicine may usefully be divided into two main categories - drugs which target metal ions in some form, whether free or protein-bound, and secondly, metal-based drugs where the central metal ion is usually the key feature of the mechanism of action. This latter category can further be subdivided into pharmacodynamic and chemotherapeutic applications, as well as those of imaging. The book summarises the chemical and biological studies on clinically used agents of lithium, gold and platinum, as well as highlighting the research on prospective new drugs, including those based on vanadium and manganese. The coverage allows a clear distinction between pharmacodynamic and therapeutic properties of metal-based drugs and focuses not only on those clinical agents in current use, but also on new drugs and uses. This book serves to fill an important niche, bridging bioinorganic and medicinal chemistry and will undoubtedly be of use to senior undergraduates and postgraduates, as well as being an invaluable asset for teachers and researchers in the discipline.
Author : Jalila Simaan
Publisher : World Scientific
ISBN 13 : 9811269505
Total Pages : 273 pages
Book Rating : 4.8/5 (112 download)
Download or read book Copper Bioinorganic Chemistry: From Health To Bioinspired Catalysis written by Jalila Simaan and published by World Scientific. This book was released on 2023-07-26 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioinorganic chemistry is an interdisciplinary research field which centers on metals in biology. Over the past few decades, advances in chemistry, biology as well as in spectroscopic methods have shed light on the role of copper in human pathologies and allowed the growing discovery of copper-containing biological systems. Following this trend, much effort is being constantly chanelled towards understanding these fundamental biological processes or enzymes. In addition, chemists are developing molecules to target copper or copper enzymes as therapeutic tools. On the other hand, inspired by the function of biological systems, small molecular weight complexes inspired by the active site of copper enzymes are being prepared and studied. These bioinspired complexes can function both as mechanistic tools and as functional catalysts for oxidative transformations.The seven chapters in this book, contributed by internationally recognized authors cover recent developments on these aspects illustrated by interdisciplinary fields from biology, chemistry, spectroscopy to bioinspired catalysis. It contains aspects ranging from human health issues (copper homeostasis in bacteria and the development of molecules as anticancer or antibacterial agents) to bioinspired catalysis.
Author : Indian Chemical Society
Publisher :
ISBN 13 :
Total Pages : 628 pages
Book Rating : 4.:/5 ( download)
Download or read book Journal of the Indian Chemical Society written by Indian Chemical Society and published by . This book was released on 2007 with total page 628 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Angela Casini
Publisher : Royal Society of Chemistry
ISBN 13 : 1788017676
Total Pages : 370 pages
Book Rating : 4.7/5 (88 download)
Download or read book Metal-based Anticancer Agents written by Angela Casini and published by Royal Society of Chemistry. This book was released on 2019-04-05 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metal-based anticancer drugs are among the most successful therapeutic agents, as evidenced by the frequent prescription of selected platinum and arsenic compounds to patients. Metal-based Anticancer Agents covers the interdisciplinary world of inorganic drug discovery and development by introducing the most prominent compound classes based on different transition metals, discussing emerging concepts and enabling methods, as well as presenting key pre-clinical and clinical aspects. Recent progress on the unique features of next-generation targeted metal-based anticancer agents, including supramolecular coordination complexes used for both therapy and drug delivery, promise a bright future beyond the benefits of pure cytotoxic activity. With contributions from global leaders in the field, this book will serve as a useful reference to established researchers as well as a practical guide to those new to metallodrugs, and postgraduate students of medicinal chemistry and metallobiology.
Author : Rudi van Eldik
Publisher : Elsevier
ISBN 13 : 0080462170
Total Pages : 299 pages
Book Rating : 4.0/5 (84 download)
Download or read book Advances in Inorganic Chemistry written by Rudi van Eldik and published by Elsevier. This book was released on 2006-01-18 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Inorganic Chemistry Volume 58 focuses on homogeneous biomimetic oxidation catalysis. Contributions by leading experts in the field cover important advances in inorganic and bioinorganic chemistry. Contributions include diversity-based approaches to selective biomimetic oxidation catalysis; the selective conversion of hydrocarbons with H2O2 using biomimetic non-heme iron and manganese oxidation catalysis; DNA oxidation by copper and manganese complexes; influences of the ligand in copper-dioxygen complex-formation and substrate oxidations; biomimetic oxidations by dinuclear and trinuclear copper complexes. In the final contribution the authors focus on green oxidation of alcohols using biomimetic copper complexes and enzymes as catalysts. Volume 58 provides another welcomed addition to the widely acclaimed series, Advances in Inorganic Chemistry. * Includes new information on the important advances in inorganic and bioinorganic chemistry * Each chapter is fully referenced * Contains comprehensive reviews written by leading experts in the field
Author : Kenneth Kam-Wing Lo
Publisher : Academic Press
ISBN 13 : 012803887X
Total Pages : 408 pages
Book Rating : 4.1/5 (28 download)
Download or read book Inorganic and Organometallic Transition Metal Complexes with Biological Molecules and Living Cells written by Kenneth Kam-Wing Lo and published by Academic Press. This book was released on 2016-12-30 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inorganic and Organometallic Transition Metal Complexes with Biological Molecules and Living Cells provides a complete overview of this important research area that is perfect for both newcomers and expert researchers in the field. Through concise chapters written and edited by esteemed experts, this book brings together a comprehensive treatment of the area previously only available through scattered, lengthy review articles in the literature. Advanced topics of research are covered, with particular focus on recent advances in the biological applications of transition metal complexes, including inorganic medicine, enzyme inhibitors, antiparasital agents, and biological imaging reagents. Geared toward researchers and students who seek an introductory overview of the field, as well as researchers working in advanced areas Focuses on the interactions of inorganic and organometallic transition metal complexes with biological molecules and live cells Foscuses on the fundamentals and their potential therapeutic and diagnostic applications Covers recent biological applications of transition metal complexes, such as anticancer drugs, enzyme inhibitors, bioconjugation agents, chemical biology tools, and bioimaging reagents
Author : Philippe Collery
Publisher : John Libbey Eurotext
ISBN 13 : 9782742002948
Total Pages : 852 pages
Book Rating : 4.0/5 (29 download)
Download or read book Metal Ions in Biology and Medicine written by Philippe Collery and published by John Libbey Eurotext. This book was released on 2000 with total page 852 pages. Available in PDF, EPUB and Kindle. Book excerpt: The objective of the 6th ISMIBM is to foster exchange of opinions between professionals and specialists working on analysis, research and applications of metal ions, trace elements and minerals in biological, biochemical, medical sciences, toxicology and environmental health. The scientific program, composed of plenary and concurrent sessions, and poster presentations is designed to promote intensive and productive dialogue among experts in these fields. A special program with short courses and mini-symposia have also been organised, featuring specialised areas including toxicology, analysis, pathology, remediation strategies, and environmental medicine. Original contributions (oral and/or poster presentations) are invited on the following themes: Metals and Environmental Health; Molecular Toxicology of Metals; Carcinogenicity of Metals; Speciation of Metals and Other Elements; Uses of Metals in Clinical Applications; Metals and Disease: Environmental and Toxicologic Pathology; Epidemiology and Occupational Health; Metals and Aging; Metals and Homeostasis; Effects of Low and High Nutritional Trace Element Status; Metals and Hormone Actions; Metals and Enzyme Activity; Metals and Chelation Therapy; Health Effects of Arsenic; Risk Assessment of Trace Element Status and Health; Advanced Methods for the Analysis of Trace Elements and Metal Ions.
Author : Marco Malavolta
Publisher : Springer
ISBN 13 : 3030037428
Total Pages : 332 pages
Book Rating : 4.0/5 (3 download)
Download or read book Trace Elements and Minerals in Health and Longevity written by Marco Malavolta and published by Springer. This book was released on 2018-11-13 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the role of trace elements in health and longevity, pursuing a biogerontological approach. It offers essential information on the impact of trace elements on molecular and physiological processes of aging, and on their impact on health in connection with aging. The major topics covered in its 11 chapters, each dedicated to a specific trace element or mineral, are: a) Role of the element in species longevity, b) Recommended intake for longevity in animal species and in the elderly, c) Deficiency and age-related disease, d) Excess/toxicity and age-related disease, and e) Interactions with drugs prescribed in the elderly. Clinical, animal and other laboratory models of interest in aging are included, which enable a more in-depth analysis to be made. The respective chapters are a mixture of overviews and more in-depth reviews in which the mechanisms of aging are described from the point of view of their specific interactions with trace elements and minerals.
Author :
Publisher :
ISBN 13 :
Total Pages : 928 pages
Book Rating : 4.2/5 (17 download)
Download or read book Australian Journal of Chemistry written by and published by . This book was released on 1982 with total page 928 pages. Available in PDF, EPUB and Kindle. Book excerpt:
