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The Chemical Biology Of Sulfur
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Book Synopsis The Chemical Biology of Sulfur by : Christopher T Walsh
Download or read book The Chemical Biology of Sulfur written by Christopher T Walsh and published by Royal Society of Chemistry. This book was released on 2020-06-17 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume aims to provide an in-depth view of the complete biochemistry of sulfur with an emphasis on aspects not covered elsewhere. Given its role in the formation of proteins and presence in the amino acids methionine and cysteine, sulfur is essential to life. Current literature on the biochemistry of sulfur is vast and widely dispersed, as such this volume is intended as a single-source for everything concerning sulfur biochemistry from metabolic roles of inorganic sulfur, to thiol and thioether chemical biology, to the university of cysteine chemistry in proteomes. Authored by a renowned biochemist and experienced writer and educator, this book is ideal for students and researchers in biochemistry, biology and the life sciences with an interest in sulfur and its role in life.
Book Synopsis Biological Interactions Of Sulfur Compounds by : Stephen C. Mitchell
Download or read book Biological Interactions Of Sulfur Compounds written by Stephen C. Mitchell and published by CRC Press. This book was released on 2003-09-02 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text focuses on the biological interactions of sulphur compounds which arise specifically from the presence of the sulphur atom within the molecule. The book opens with introductory chapters on the chemistry and biology of sulphur, before tackling the field by introducing compounds which share a common chemical combination. In general, following a description of the uses and impact upon the biological field, specific chemical group characteristics are discussed together with the biological activity and structure-activity relationships where known. The toxicity of such compounds, their consequences in biochemical and clinical terms, and their mechanisms of biological interaction are then addressed.
Book Synopsis Biochemistry of Sulfur by : Ryan J. Huxtable
Download or read book Biochemistry of Sulfur written by Ryan J. Huxtable and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: There can be few elements with a biochemistry as coherent as that of sulfur. This important element is crucial to myriad aspects of metabo lism, catalysis, and structure. The plurality of functions in which sulfur is involved derives squarely from the numerous oxidation states in which it may exist, some having great stability, some being capable of ready redox interconversions, and yet others having great instability. As a result, the flux of sulfur from the geosphere through the various kingdoms of life leaves few biochemical processes unaffected. Although there are large gaps in the fabric of our basic knowledge of sulfur biochemistry, it is sufficiently framed to allow a unified and organized story, a story which many of the best-known names in bio chemistry have helped to write. It has been both a task and a privilege to try and summarize this story, one that is enormous, complex, fast moving, still developing and, above all, exciting. I suppose that no mo nographer of such a vast subject could be satisfied with his efforts. It is unfortunately probable that in attempting this task I have made as many errors as a Stilton cheese has blue streaks, and as many omissions as a Swiss cheese has holes. Perfection is not to be achieved in a monograph. Inasmuch as I have succeeded, the credit belongs to those whose efforts gave us the knowledge we have. Where I have failed, the fault is only mine.
Book Synopsis Organic Sulfur Chemistry by : Shigeru Oae
Download or read book Organic Sulfur Chemistry written by Shigeru Oae and published by CRC Press. This book was released on 1992-06-15 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: his volume provides an organic chemical perspective on the biochemistry of sulfur compounds. The authors have applied the principles of various biochemical processes to a general theory of the biochemical phenomena of sulfur compounds. These processes include metabolisms of inorganic sulfur compounds and metalloenzymes, mechanisms of thiolesterase actions, functions of disulfides in proteins, and biochemical redox reactions. Organic Sulfur Chemistry: Biochemical Aspects is an ideal reference for students and researchers in both biochemistry and organic chemistry.
Book Synopsis Hydrogen Sulfide by : Michael D. Pluth
Download or read book Hydrogen Sulfide written by Michael D. Pluth and published by John Wiley & Sons. This book was released on 2022-09-21 with total page 596 pages. Available in PDF, EPUB and Kindle. Book excerpt: HYDROGEN SULFIDE Covers H2S interactions, methods of detection and delivery in biological environments, and a wide range of applications Research on hydrogen sulfide (H2S) spans diverse disciplines including chemistry, biology, and physiology. In recent years, new materials and approaches have been developed to deliver H2S and related reactive sulfur species in various clinical contexts. Although many biological pathways involving H2S are complex, all are governed by fundamental chemical interactions between reactive sulfur species and other molecular entities. Hydrogen Sulfide: Chemical Biology Basics, Detection Methods, Therapeutic Applications, and Case Studies provides the foundation required for understanding the fundamental chemical biology of H2S while highlighting the compound’s therapeutic potential and medicinal applications. This book covers key aspects of H2S chemical biology, including the fundamental chemistry of reactive sulfur species; the measurement, detection, and delivery of H2S in biological environments; and the therapeutic and medicinal uses of exogenous H2S delivery in various pharmacologically relevant systems. Throughout the text, editor Michael Pluth and chapter contributors discuss the opportunities and future of the multidisciplinary field. Provides approaches for delivering H2S with relevance to biological and therapeutic applications Describes complex interactions of H2S with bioinorganic complexes and reactive sulfur, nitrogen, and oxygen species Summarizes advances in available tools to detect, measure, and modulate H2S levels in biological environments, such as real-time methods for H2S fluorescence imaging in live cell and animal systems Helps readers understand known systems and make connections to new and undiscovered pathways and mechanisms of action Includes in-depth case studies of different systems in which H2S plays an important role Hydrogen Sulfide: Chemical Biology Basics, Detection Methods, Therapeutic Applications, and Case Studies is an important source of current knowledge for researchers, academics, graduate students, and industrial scientists in the fields of redox biology, hydrogen sulfide research, and medicinal chemistry of small biological molecules.
Book Synopsis Sulfur-Centered Reactive Intermediates in Chemistry and Biology by : C. Chatgilialoglu
Download or read book Sulfur-Centered Reactive Intermediates in Chemistry and Biology written by C. Chatgilialoglu and published by Springer Science & Business Media. This book was released on 2013-03-08 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: A wonderfully successful NATO Advanced Study Institute on "Sulfur-Centered Reactive Intermediates in Chemistry and Biology" was held 18-30 June, 1989, at the Hotel Villa del Mare in Maratea, Italy. Despite the beautiful setting with mountains behind us and over looking the clear blue Mediterranean Sea under a cloudless sky (and with a private beach available), the lectures were extremely well attended. While some credit can go to the seriousness of the students, more must go to the calibre of speakers and the high quality of C. Chatgilialoglu, and Co-Director, Professor K. -D. their presentations. The Director, Dr. Asmus, are to be congratulated for putting together such an outstanding scientific program. Dr. Chatgilialoglu is also to be commended for arranging an equally stimulating social pro gram which included bus, train and boat trips to many local sites of interest. It was particularly fitting that a meeting on the chemistry and biochemistry of sulfur should be held in Italy since Italian chemists have made major contributions to our under standing of the organic chemistry of sulfur, including the chemistry of its reactive inter mediates. The early Italian interest in sulfur chemistry arose from the fact that Italy, or more specifically, Sicily, was a major world producer of sulfur prior to the development and exploitation of the Frasch process in Texas and Louisiana.
Book Synopsis Reactive Sulfur Species in Biology and Medicine by : John P Toscano
Download or read book Reactive Sulfur Species in Biology and Medicine written by John P Toscano and published by Mdpi AG. This book was released on 2023-10-24 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hydrogen sulfide (H2S) is a naturally occurring signaling molecule produced in vivo and plays a pivotal role in regulating a wide array of physiological processes. Additionally, emerging findings have illuminated that many of the biological effects initially attributed to H2S may actually stem from other reactive sulfur species (RSS), including hydropersulfides (RSSH) and various higher-order polysulfur species (RSSnH, RSSnR, and HSnH, where n > 1). These studies have underscored the contributions of these species to essential cellular processes, such as the efficient scavenging of reactive oxygen species and electrophiles, and their influence on mitochondrial function. Nonetheless, the chemistry of RSS remains challenging due to their inherently reactive nature, and their precise measurement within biological systems continues to pose a formidable challenge. This compilation of reprints focuses on recent advancements in the field of H2S/RSS chemical biology. It encompasses original research studies and comprehensive reviews, all geared towards exploring the therapeutic potential of H2S/RSS donors in the treatment of various conditions, including cancer, neurological disorders, and cardiovascular disease. Furthermore, it delves into the molecular mechanisms and physiological roles played by RSS along with the development of methodologies for quantifying and measuring the distribution of RSS within biological systems.
Book Synopsis Iron-Sulfur Clusters in Chemistry and Biology by : Tracey Rouault
Download or read book Iron-Sulfur Clusters in Chemistry and Biology written by Tracey Rouault and published by Walter de Gruyter GmbH & Co KG. This book was released on 2014-08-20 with total page 672 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume on iron-sulfur proteins includes chapters that describe the initial discovery of iron-sulfur proteins in the 1960s to elucidation of the roles of iron sulfur clusters as prosthetic groups of enzymes, such as the citric acid cycle enzyme, aconitase, and numerous other proteins, ranging from nitrogenase to DNA repair proteins. The capacity of iron sulfur clusters to accept and delocalize single electrons is explained by basic chemical principles, which illustrate why iron sulfur proteins are uniquely suitable for electron transport and other activities. Techniques used for detection and stabilization of iron-sulfur clusters, including EPR and Mossbauer spectroscopies, are discussed because they are important for characterizing unrecognized and elusive iron sulfur proteins. Recent insights into how nitrogenase works have arisen from multiple advances, described here, including studies of high-resolution crystal structures. Numerous chapters discuss how microbes, plants, and animals synthesize these complex prosthetic groups, and why it is important to understand the chemistry and biogenesis of iron sulfur proteins. In addition to their vital importance in mitochondrial respiration, numerous iron sulfur proteins are important in maintenance of DNA integrity. Multiple rare human diseases with different clinical presentations are caused by mutations of genes in the iron sulfur cluster biogenesis pathway. Understanding iron sulfur proteins is important for understanding a rapidly expanding group of metabolic pathways important in all kingdoms of life, and for understanding processes ranging from nitrogen fixation to human disease.
Download or read book Sulfur Chemistry written by Xuefeng Jiang and published by Springer Nature. This book was released on 2019-08-28 with total page 475 pages. Available in PDF, EPUB and Kindle. Book excerpt: The series Topics in Current Chemistry Collections presents critical reviews from the journal Topics in Current Chemistry organized in topical volumes. The scope of coverage is all areas of chemical science including the interfaces with related disciplines such as biology, medicine and materials science. The goal of each thematic volume is to give the non-specialist reader, whether in academia or industry, a comprehensive insight into an area where new research is emerging which is of interest to a larger scientific audience. Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years are presented using selected examples to illustrate the principles discussed. The coverage is not intended to be an exhaustive summary of the field or include large quantities of data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Contributions also offer an outlook on potential future developments in the field.
Book Synopsis Natural Sulfur Compounds by : Doriano Cavallini
Download or read book Natural Sulfur Compounds written by Doriano Cavallini and published by Springer. This book was released on 1980-05 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: The third International Meeting on "Low Molecular Weight Sulfur Containing Natural Products,"sponsored by the International Union of Pure and Applied Chemistry, was held in the historical building of the Accademia Nazionale dei Lincei, Rome, Italy, June 18-21, 1979. The symposium was held in order to exchange knowledge in the intriguing and complex field of sulfur biochemistry. This theme brought together scientists from many speciali zed areas from organic and physical chemistry to biology and medicine. The interdisciplinary nature of the meeting gave to the participants the opportunity to discuss pro blems of common interest approached from different scienti fic standpoints. This volume contains 47 contributions presented at the meeting which mainly deal with new structural and metabolic aspects of sulfur biochemistry. An important aspect of such a scientific meeting is the rapid publication of the proceedings. Through the cooperation of the authors in providing "camera ready" copies of their manuscripts, the good efforts of the Orga nizing Committee, and the Plenum Press Publishing Co., it has been possible to publish this book within a few months of the meeting.
Book Synopsis Sulfur-based Reactive Species in Chemistry and Biology by :
Download or read book Sulfur-based Reactive Species in Chemistry and Biology written by and published by . This book was released on 2014 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Organic Sulfur Chemistry by : Shigeru Oae
Download or read book Organic Sulfur Chemistry written by Shigeru Oae and published by CRC Press. This book was released on 2018-05-04 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains fundamental knowledge regarding the structure and mechanisms of organic sulfur chemistry. Topics include sulfur bondings, effects of sulfur groups, stereochemistry around sulfur, substitution, ligand coupling within s-sulfurane, oxidation, reduction and rearrangement. References in this work total over 2,300. Anyone with an interest in organic sulfur chemistry will find this book to be fascinating reading.
Book Synopsis Metabolism of Sulfur Compounds by : David Greenberg
Download or read book Metabolism of Sulfur Compounds written by David Greenberg and published by Elsevier. This book was released on 2012-12-02 with total page 637 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metabolic Pathways, Third Edition: Volume VII: Metabolism of Sulfur Compounds deals with various aspects of the metabolism and biosynthesis of sulfur compounds such as coenzyme A, biotin, thiamine, and lipoic acid. The biochemistry of glutathione and the sulfur cycle is also discussed, together with sulfate activation and transfer; oxidative metabolism of cysteine and cystine in animal tissues; and enzyme defects in sulfur amino acid metabolism in humans. This volume is comprised of 15 chapters and begins with a discussion on the pathways of biosynthesis and dissimilation of coenzyme A, as well as the metabolic fate of exogenous coenzyme A in animals. The reader is then introduced to the chemistry, biosynthesis, metabolism, biological role, and biodegradation of biotin; the biosynthesis and function of thiamine; and the biosynthesis, dissimilation, and metabolic role of lipoic acid. Other sulfur compounds considered in this text are glutathione, cysteine and cystine, riboflavin, thiosulfate sulfurtransferase, mercaptopyruvate sulfurtransferase, and methionine. The final chapter is devoted to human diseases associated with enzyme defects in sulfur amino acid metabolism. This book will be a useful resource for biologists and biochemists.
Book Synopsis Natural Sulfur Compounds by : Doriano Cavallini
Download or read book Natural Sulfur Compounds written by Doriano Cavallini and published by . This book was released on 1980-05-01 with total page 572 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Characterization, Properties and Applications by : Tracey Rouault
Download or read book Characterization, Properties and Applications written by Tracey Rouault and published by Walter de Gruyter GmbH & Co KG. This book was released on 2017-08-21 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume on iron-sulfur proteins includes chapters that describe the initial discovery of iron-sulfur proteins in the 1960s to elucidation of the roles of iron sulfur clusters as prosthetic groups of enzymes, such as the citric acid cycle enzyme, aconitase, and numerous other proteins, ranging from nitrogenase to DNA repair proteins. The capacity of iron sulfur clusters to accept and delocalize single electrons is explained by basic chemical principles, which illustrate why iron sulfur proteins are uniquely suitable for electron transport and other activities. Techniques used for detection and stabilization of iron-sulfur clusters, including EPR and Mossbauer spectroscopies, are discussed because they are important for characterizing unrecognized and elusive iron sulfur proteins. Recent insights into how nitrogenase works have arisen from multiple advances, described here, including studies of high-resolution crystal structures.
Book Synopsis Sulphur in Biology by : Katherine Elliott
Download or read book Sulphur in Biology written by Katherine Elliott and published by John Wiley & Sons. This book was released on 2009-09-16 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.
Book Synopsis The Chemistry of Organic Sulfur Compounds by : Norman Kharasch
Download or read book The Chemistry of Organic Sulfur Compounds written by Norman Kharasch and published by Elsevier. This book was released on 2013-10-22 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Chemistry of Organic Sulfur Compounds deals with the chemistry of organic sulfur compounds such as thiocyanates, 1-alkynyl thioethers, thiols, and olefins. Topics covered range from the mechanisms of Raney nickel desulfuration to olefin sulfide chemistry, desulfonylation reactions, and alkaline decomposition of aliphatic disulfides. The reaction of cyanide with cystine and cystine peptides is also discussed. This volume is comprised of 15 chapters and begins with an introduction to electron correlation and bond properties in some selected sulfur compounds including thionyl and sulfuryl fluoride. The following chapters explore the mechanisms of Raney nickel desulfuration; isomerization of organic thiocyanates; polyfluoroalkyl derivatives of sulfur; anionic oxidation of thiols and co-oxidation of thiols with olefins; and the chemistry of the 1,2-sithiole ring. Thiohydantoins, thiophosgene, and the alkaline decomposition of aliphatic disulfides are also considered. The final chapter is devoted to oxidation of disulfides, with special reference to cystine. This book will be a useful resource for organic chemists.
