The Biology And Clinical Applications Of Interleukin 2

Download The Biology And Clinical Applications Of Interleukin 2 full books in PDF, epub, and Kindle. Read online The Biology And Clinical Applications Of Interleukin 2 ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!

The Biology and Clinical Applications of Interleukin-2

Author : Robert C. Rees
Publisher : IRL Press
ISBN 13 :
Total Pages : 208 pages
Book Rating : 4.3/5 (91 download)

DOWNLOAD NOW!

Book Synopsis The Biology and Clinical Applications of Interleukin-2 by : Robert C. Rees

Download or read book The Biology and Clinical Applications of Interleukin-2 written by Robert C. Rees and published by IRL Press. This book was released on 1990 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: The molecular structure of interleukin-2 (IL-2) and that of its receptor subunits provide a basis for understanding lymphocyte activation by IL-2 and the generation of effector cells capable of mediating cytotoxicity towards tumors. This book provides an up-to-date account of IL-2, its effect on lymphocyte function, and clinical applications. Internationally know experts review the molecular aspects of cell signalling, giving insight on the in vivo pathways of activation likely to be important in determining clinical responses. They also examine the use of cytokines, particularly IL-2, in the treatment of cancer, and describe the results of recent clinical trials using IL-2, as well as of adoptive cell therapy. Providing a clear account of recent progress, the book also reviews the problems involved in attempting to improve the therapeutic benefit of IL-2, along with the importance of mechanisms which subverse IL-2 responses. This is the most up-to-date account of molecular research and clinical trials in this area, and will be of great benefit to students and researchers in immunology, pharmacology, biochemistry, and oncology who are interested in this vitally important topic.

The role of interleukin-2 in the treatment of cancer patients

Author : J. Wagstaff
Publisher : Springer Science & Business Media
ISBN 13 : 9401117535
Total Pages : 195 pages
Book Rating : 4.4/5 (11 download)

DOWNLOAD NOW!

Book Synopsis The role of interleukin-2 in the treatment of cancer patients by : J. Wagstaff

Download or read book The role of interleukin-2 in the treatment of cancer patients written by J. Wagstaff and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recombinant human interleukin-2 became available for clinical use in the mid 1980s. Recent years have seen an enormous amount of clinical research with this cytokine and interleukin-2 has now been registered for use in a number of European countries for the treatment of metastatic renal cell carcinoma. This book is designed to provide the clinical oncologist wishing to use interleukin-2 with a basic background concerning the biology of the agent, a discussion concerning practical aspects, of its clinical use including management of toxicity and an overview of the clinical results together with a description of how this internesting cytokine might be developed in the future.

Clinical Applications of Cytokines

Author : Joost J. Oppenheim
Publisher : Oxford University Press, USA
ISBN 13 : 9780195071290
Total Pages : 406 pages
Book Rating : 4.0/5 (712 download)

DOWNLOAD NOW!

Book Synopsis Clinical Applications of Cytokines by : Joost J. Oppenheim

Download or read book Clinical Applications of Cytokines written by Joost J. Oppenheim and published by Oxford University Press, USA. This book was released on 1993 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: The driving force for research on cytokines has always been their clinical promise. Their biological properties suggested a key role in hematopoiesis, immunity, tumor genesis, hemostasis, vascularization, repair of connective tissues and integration of the immune system with the neuroendocrine system. Animal studies have shown that cytokines could be used as effective biotherapeutics with easily manageable and reversible toxicities. Clinical trials have confirmed these findings, culminating in the licensing of a number of the cytokines such as interferon alpha, interferon gamma, interleukin 2, erythropoietin, granulocyte colony stimulating factor, and granulocyte-macrophage colony stimulating factor. Many other cytokines are in clinical trials. This is the first comprehensive volume on the cytokines written primarily from a medical perspective. After presenting background information about the structure, production, assays and systemic effects of cytokines and their receptors, it is organized around diseases and organ systems. Infectious diseases, autoimmunity, immunodeficiency states, defective hematopoiesis, allergies, injury repair, cancer, vascular and skin diseases, and neurological disorders are all covered. This work reviews the role that cytokines play in the pathogenesis, diagnosis and therapy of each disease. The authors assess both the current state of the art and the potential for future applications.

Interleukin-2 and Killer Cells in Cancer

Author : Eva Lotzova
Publisher : CRC Press
ISBN 13 : 1351082248
Total Pages : 381 pages
Book Rating : 4.3/5 (51 download)

DOWNLOAD NOW!

Book Synopsis Interleukin-2 and Killer Cells in Cancer by : Eva Lotzova

Download or read book Interleukin-2 and Killer Cells in Cancer written by Eva Lotzova and published by CRC Press. This book was released on 2018-02-01 with total page 381 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first-and only-publication available which provides the most recent information in this particular field of biomedicine. Interleukin-2 (IL-2) and IL-2 activated killer cells have been shown to have a potential in the treatment of a variety of human malignant diseases. This work comprehensively summarizes basic aspects of IL-2 as well as its clinical application, therefore making all these aspects easily accessible to the readers. Because of the clinical significance of this molecule in the treatment of cancer, the basic and clinical investigations in the IL-2 field are rapidly expanding, together with the interest of the scientific and medical community. This book is an excellent educational and teaching tool for scientists, clinicians, and students. Those who already have expertise in research in the IL-2 area will find this reference indispensible.

Interleukin-2

Author : Jonathan Waxman
Publisher : Wiley-Blackwell
ISBN 13 : 9780632030422
Total Pages : 256 pages
Book Rating : 4.0/5 (34 download)

DOWNLOAD NOW!

Book Synopsis Interleukin-2 by : Jonathan Waxman

Download or read book Interleukin-2 written by Jonathan Waxman and published by Wiley-Blackwell. This book was released on 1992-11-16 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interleukin-2 "supercharges" the immune system by promoting the growth of activated T-lymphocytes and augmenting their cell-killing activities. It, therefore, has a role in cancer and infection and has been licensed for use in the former. The book will focus on the areas of molecular biology, immunoregulation and the generation of specific or non-specific cytotoxic effector cells and their role in tumour immunotherapy. Dr Balkwill is one of the UK's leading experts in cytokine research and Dr Waxman is an experienced oncologist working with cytokines in a clinical setting. The book will therefore be balanced between a scientific and a clinical angle

Therapeutic Applications of Interleukin-2

Author : Michael Atkins
Publisher : CRC Press
ISBN 13 : 9780824788094
Total Pages : 520 pages
Book Rating : 4.7/5 (88 download)

DOWNLOAD NOW!

Book Synopsis Therapeutic Applications of Interleukin-2 by : Michael Atkins

Download or read book Therapeutic Applications of Interleukin-2 written by Michael Atkins and published by CRC Press. This book was released on 1993-03-08 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering everything from basic science to disease-specific clinical trials, current applications and future directions, this book discusses the novel biological response modifier interleukin-2. This immunoactive therapy is designed for use in the treatment of metastatic renal cancer and, possibly, melanoma and other malignancies. Examining the value and toxic manifestations of different treatment regimens, this text: describes the biochemistry of the IL-2 receptor, the activation of natural killer cells and the lymphokine-activated killer (LAK) cell phenomenon; explicates tumour-infiltrating lymphocytes and the effect of IL-2 on in vitro assays of immune function; emphasizes high-dose IL-2 therapy in renal cell carcinoma and malignant melanoma; reviews in detail IL-2 treatment of other solid tumours and haematologic malignancies; illustrates the use of lower dose regimens, regional administration and combinations of IL-2 with other therapies; elucidates toxicities associated with IL-2, their pathogenesis and clinical management; and highlights future developments, including gene therapy and the co-administration of cytokine antagonists to reduce toxicity.

Interleukin-2 and Killer Cells in Cancer

Author : Eva Lotzova
Publisher : CRC Press
ISBN 13 : 9780849353888
Total Pages : 384 pages
Book Rating : 4.3/5 (538 download)

DOWNLOAD NOW!

Book Synopsis Interleukin-2 and Killer Cells in Cancer by : Eva Lotzova

Download or read book Interleukin-2 and Killer Cells in Cancer written by Eva Lotzova and published by CRC Press. This book was released on 1989-12-21 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first-and only-publication available which provides the most recent information in this particular field of biomedicine. Interleukin-2 (IL-2) and IL-2 activated killer cells have been shown to have a potential in the treatment of a variety of human malignant diseases. This work comprehensively summarizes basic aspects of IL-2 as well as its clinical application, therefore making all these aspects easily accessible to the readers. Because of the clinical significance of this molecule in the treatment of cancer, the basic and clinical investigations in the IL-2 field are rapidly expanding, together with the interest of the scientific and medical community. This book is an excellent educational and teaching tool for scientists, clinicians, and students. Those who already have expertise in research in the IL-2 area will find this reference indispensible.

Cytokine Knockouts

Author : Scott K. Durum
Publisher : Springer Science & Business Media
ISBN 13 : 1475727534
Total Pages : 498 pages
Book Rating : 4.4/5 (757 download)

DOWNLOAD NOW!

Book Synopsis Cytokine Knockouts by : Scott K. Durum

Download or read book Cytokine Knockouts written by Scott K. Durum and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: My personal history in the field of cytokines had an initial period of several years during which my student and then colleague, Werner Muller, tried in vain to attract me to them. My interest always vanished when I was confronted with complex data pointing to func tional redundancy of cytokines in cell culture systems. When gene targeting in the mouse germline became possible, this frustration came to an end. We and others immediately embarked on analyzing the in vivo function of cytokines and the problem of functional redundancy with this powerful new approach. The early cytokine gene knockouts performed by colleagues in Wiirzburg (IL-2) and by ourselves (IL-4 and IL-l 0) seemed to give clear answers and at the same time led to surprises: Each of these cytokines apparently had its own special and irreplaceable function, and this function could be quite distinct from what had been anticipated from functional experiments in vitro. Al though the latter finding is of course a wonderful incentive for fur ther research, the former is pleasing in a general sense since it highlights the value of each of those one hundred thousand genes or so in our genome, cherished by evolution to become respectable mem bers of the community. Even in the present era of "genomics" there will be no way around the careful functional analysis of each gene by itself.

Encyclopedia of Inflammatory Diseases

Author :
Publisher : Birkhäuser
ISBN 13 : 9783764385309
Total Pages : 0 pages
Book Rating : 4.3/5 (853 download)

DOWNLOAD NOW!

Book Synopsis Encyclopedia of Inflammatory Diseases by :

Download or read book Encyclopedia of Inflammatory Diseases written by and published by Birkhäuser. This book was released on 2016-09-15 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inflammation has become one of the most exciting and rewarding areas of medical research. Recent years have seen a revolution in our understanding of how blood and tissue cells interact and of the intracellular mechanisms controlling their activation. This has revealed the underlying inflammatory pathology of many diseases and provided multiple new targets for anti-inflammatory and immunomodulatory therapy. The Encyclopedia of Inflammatory Diseases will cover the following areas: Inflammatory Processes and Cells Inflammatory Diseases Mediators of Inflammation Pharmacology of Inflammation Since inflammatory diseases and their therapy cover a broad range of scientific and medical fields, the encyclopedia will be co-edited by four international experts, a clinician and three researchers from the disciplines of immunology, biochemistry, and pharmacology, in this way providing students, basic and clinical scientists and practitioners in academia, hospitals and industry with valuable interlinked information. This living project will serve as a reliable and comprehensive data pool for everybody working in inflammation research. Owing to its dynamic nature, it will grow with time and future editions, becoming an indispensible source of information for academia, clinical practitioners and industry.

Innovative Medicine

Author : Kazuwa Nakao
Publisher : Springer
ISBN 13 : 4431556516
Total Pages : 330 pages
Book Rating : 4.4/5 (315 download)

DOWNLOAD NOW!

Book Synopsis Innovative Medicine by : Kazuwa Nakao

Download or read book Innovative Medicine written by Kazuwa Nakao and published by Springer. This book was released on 2015-10-13 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is devoted to innovative medicine, comprising the proceedings of the Uehara Memorial Foundation Symposium 2014. It remains extremely rare for the findings of basic research to be developed into clinical applications, and it takes a long time for the process to be achieved. The task of advancing the development of basic research into clinical reality lies with translational science, yet the field seems to struggle to find a way to move forward. To create innovative medical technology, many steps need to be taken: development and analysis of optimal animal models of human diseases, elucidation of genomic and epidemiological data, and establishment of “proof of concept”. There is also considerable demand for progress in drug research, new surgical procedures, and new clinical devices and equipment. While the original research target may be rare diseases, it is also important to apply those findings more broadly to common diseases. The book covers a wide range of topics and is organized into three complementary parts. The first part is basic research for innovative medicine, the second is translational research for innovative medicine, and the third is new technology for innovative medicine. This book helps to understand innovative medicine and to make progress in its realization.

Research and Clinical Applications of Targeting Gastric Neoplasms

Author : Brendan Jenkins
Publisher : Elsevier
ISBN 13 : 0323855636
Total Pages : 370 pages
Book Rating : 4.3/5 (238 download)

DOWNLOAD NOW!

Book Synopsis Research and Clinical Applications of Targeting Gastric Neoplasms by : Brendan Jenkins

Download or read book Research and Clinical Applications of Targeting Gastric Neoplasms written by Brendan Jenkins and published by Elsevier. This book was released on 2021-07-23 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research and Clinical Applications of Targeting Gastric Neoplasms provides a comprehensive overview of gastrointestinal cancers, covering preclinical research and clinical findings related to risk factors, current treatment regimens (including immunotherapy), screening/detection methods, etiology of disease, precision medicine and future perspectives. Gastrointestinal cancers rank among the most lethal and common worldwide, and as such, there is intense research into their diverse causes and treatment options. This reference provides a consolidation of the research, making it a perfect resource for basic science and clinical researchers as well as oncologists who work in gastroenterology and GI tract cancer fields. Provides comprehensive coverage of preclinical research and the clinical aspects of gastric cancer Presents future perspectives from leading researchers in the field who provide the potential for furthering research topics Combines the expertise of researchers in GI tracts, cancer, immunity, immunology, infectious disease and microbiology for an interdisciplinary approach

Vitamin D

Author : Michael F. Holick
Publisher : Springer Science & Business Media
ISBN 13 : 1475728611
Total Pages : 456 pages
Book Rating : 4.4/5 (757 download)

DOWNLOAD NOW!

Book Synopsis Vitamin D by : Michael F. Holick

Download or read book Vitamin D written by Michael F. Holick and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Nutrition and Health series of books has as an overriding mission to provide health professionals with texts that are considered essential because each includes: a synthesis of the state of the science; timely, in-depth reviews by the leading researchers in their respective fields; extensive, up-to-date fully annotated reference lists; a detailed index; relevant tables and figures; identification of paradigm shifts and the consequences; of information between chapters, but targeted, inter-chapter refer virtually no overlap rals, suggestions of areas for future research; and balanced, data-driven answers to patient questions that are based on the totality of evidence rather than the findings of any single study. The series volumes are not the outcome of a symposium. Rather, each editor has the potential to examine a chosen area with a broad perspective, both in subject matter as well as in the choice of chapter authors. The international perspective, especially with regard to public health initiatives, is emphasized where appropriate. The editors, whose training is both research and practice oriented, have the opportunity to develop a primary objective for their book, define the scope and focus, and then invite the leading authori ties from around the world to be part of their initiative. The authors are encouraged to provide an overview of the field, discuss their own research, and relate the research de findings to potential human health consequences.

Cumulated Index Medicus

Author :
Publisher :
ISBN 13 :
Total Pages : 1516 pages
Book Rating : 4.3/5 (243 download)

DOWNLOAD NOW!

Book Synopsis Cumulated Index Medicus by :

Download or read book Cumulated Index Medicus written by and published by . This book was released on 1994 with total page 1516 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Interleukins

Author : Payam Behzadi
Publisher : BoD – Books on Demand
ISBN 13 : 1839690984
Total Pages : 146 pages
Book Rating : 4.8/5 (396 download)

DOWNLOAD NOW!

Book Synopsis Interleukins by : Payam Behzadi

Download or read book Interleukins written by Payam Behzadi and published by BoD – Books on Demand. This book was released on 2021-07-14 with total page 146 pages. Available in PDF, EPUB and Kindle. Book excerpt: The immune system recruits a wide range of molecule groups and categories, each of which has its own function, property, and structure. Among these, interleukins play a pivotal role in supporting the immune and non-immune systems of the human body. Interleukins as effective cytokines participate in different conditions such as homeostasis, infectious diseases, autoimmune diseases, and cancers. This unique property of interleukins makes them invaluable biomarkers that can be used as important biosensors. This book is divided into three sections: “Interleukins’ Classification and Evolutionary Features”, “Autoimmune Diseases and Low Immune System”, and “Cancer and Injuries”. Chapters examine the role of various interleukins in conditions such as leukemia, rheumatoid arthritis, and allergic and autoimmune diseases.

Acute Phase Proteins Molecular Biology, Biochemistry, and Clinical Applications

Author : Andrzej Mackiewicz
Publisher : CRC Press
ISBN 13 : 1000141977
Total Pages : 706 pages
Book Rating : 4.0/5 (1 download)

DOWNLOAD NOW!

Book Synopsis Acute Phase Proteins Molecular Biology, Biochemistry, and Clinical Applications by : Andrzej Mackiewicz

Download or read book Acute Phase Proteins Molecular Biology, Biochemistry, and Clinical Applications written by Andrzej Mackiewicz and published by CRC Press. This book was released on 2020-07-24 with total page 706 pages. Available in PDF, EPUB and Kindle. Book excerpt: Acute Phase Proteins covers all major aspects of acute phase proteins (APP) starting with molecular mechanisms regulating their synthesis and ending with their functional significance. The book features 36 chapters addressing such topics as acute phase response and the APP; major APP and their structure and functions; regulation of APP synthesis, the cytokines and hormones implicated in these processes, and molecular mechanisms involved; signal transduction of cytokines in hepatocytes and posttranscriptional processes; and quantitative and qualitative evaluation of APP in clinical practice. The book will be an important reference for immunologists, molecular biologists, cellular biologists, biochemists, and clinical chemists.

Cytokines in Animal Health and Disease

Author : Michael J. Myers
Publisher : CRC Press
ISBN 13 : 1000148432
Total Pages : 486 pages
Book Rating : 4.0/5 (1 download)

DOWNLOAD NOW!

Book Synopsis Cytokines in Animal Health and Disease by : Michael J. Myers

Download or read book Cytokines in Animal Health and Disease written by Michael J. Myers and published by CRC Press. This book was released on 2020-08-26 with total page 486 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work offers comprehensive, up-to-date coverage of cytokine biology in veterinary and agricultural species, describing the role of cytokines in physiological and pathological processes. It addresses recent advances and new information on the function of cytokines in reproduction, detoxification of xenobiotics, growth modulation and other areas, and discusses the approaches to and pitfalls of studying cytokines in animals.

Nanoscience in Dermatology

Author : Michael R. Hamblin
Publisher : Academic Press
ISBN 13 : 0128029455
Total Pages : 402 pages
Book Rating : 4.1/5 (28 download)

DOWNLOAD NOW!

Book Synopsis Nanoscience in Dermatology by : Michael R. Hamblin

Download or read book Nanoscience in Dermatology written by Michael R. Hamblin and published by Academic Press. This book was released on 2016-08-13 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanoscience in Dermatology covers one of the two fastest growing areas within dermatological science, nanoscience and nanotechnology in dermatology. Recently, great progress has been made in the research and development of nanotechnologies and nanomaterials related to various applications in medicine and, in general, the life sciences. There is increasing enthusiasm for nanotechnology applications in dermatology (drug delivery, diagnostics, therapeutics, imaging, sensors, etc.) for understanding skin biology, improving early detection and treatment of skin diseases, and in the design and optimization of cosmetics. Light sensitive nanoparticles have recently been explored, opening a new era for the combined applications of light with nanotechnology, also called photonanodermatology. However, concerns have been raised regarding the adverse effects of intentional and unintentional nanoparticle exposure and their toxicity. Written by experts working in these exciting fields, this book extensively covers nanotechnology applications, together with the fundamentals and toxicity aspects. It not only addresses current applications of nanotechnology, but also discusses future trends of these ever-growing and rapidly changing fields, providing scientists and dermatologists with a clear understanding of the advantages and challenges of nanotechnology in skin medicine. Provides knowledge of current and future applications of nanoscience and nanotechnology in dermatology Outlines the fundamentals, methods, toxicity aspects, and other relevant aspects for nanotechnology based applications in dermatology Coherently structured book written by experts working in the fields covered