The Art of Theoretical Biology

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Publisher : Springer Nature
ISBN 13 : 3030334716
Total Pages : 152 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis The Art of Theoretical Biology by : Franziska Matthäus

Download or read book The Art of Theoretical Biology written by Franziska Matthäus and published by Springer Nature. This book was released on 2020-04-16 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt: This beautifully crafted book collects images, which were created during the process of research in all fields of theoretical biology. Data analysis, numerical treatment of a model, or simulation results yield stunning images, which represent pieces of art just by themselves. The approach of the book is to present for each piece of visualization a lucid synopsis of the scientific background as well as an outline of the artistic vision.

Quantitative Biology

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Publisher : MIT Press
ISBN 13 : 0262038080
Total Pages : 729 pages
Book Rating : 4.2/5 (62 download)

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Book Synopsis Quantitative Biology by : Brian Munsky

Download or read book Quantitative Biology written by Brian Munsky and published by MIT Press. This book was released on 2018-08-21 with total page 729 pages. Available in PDF, EPUB and Kindle. Book excerpt: An introduction to the quantitative modeling of biological processes, presenting modeling approaches, methodology, practical algorithms, software tools, and examples of current research. The quantitative modeling of biological processes promises to expand biological research from a science of observation and discovery to one of rigorous prediction and quantitative analysis. The rapidly growing field of quantitative biology seeks to use biology's emerging technological and computational capabilities to model biological processes. This textbook offers an introduction to the theory, methods, and tools of quantitative biology. The book first introduces the foundations of biological modeling, focusing on some of the most widely used formalisms. It then presents essential methodology for model-guided analyses of biological data, covering such methods as network reconstruction, uncertainty quantification, and experimental design; practical algorithms and software packages for modeling biological systems; and specific examples of current quantitative biology research and related specialized methods. Most chapters offer problems, progressing from simple to complex, that test the reader's mastery of such key techniques as deterministic and stochastic simulations and data analysis. Many chapters include snippets of code that can be used to recreate analyses and generate figures related to the text. Examples are presented in the three popular computing languages: Matlab, R, and Python. A variety of online resources supplement the the text. The editors are long-time organizers of the Annual q-bio Summer School, which was founded in 2007. Through the school, the editors have helped to train more than 400 visiting students in Los Alamos, NM, Santa Fe, NM, San Diego, CA, Albuquerque, NM, and Fort Collins, CO. This book is inspired by the school's curricula, and most of the contributors have participated in the school as students, lecturers, or both. Contributors John H. Abel, Roberto Bertolusso, Daniela Besozzi, Michael L. Blinov, Clive G. Bowsher, Fiona A. Chandra, Paolo Cazzaniga, Bryan C. Daniels, Bernie J. Daigle, Jr., Maciej Dobrzynski, Jonathan P. Doye, Brian Drawert, Sean Fancer, Gareth W. Fearnley, Dirk Fey, Zachary Fox, Ramon Grima, Andreas Hellander, Stefan Hellander, David Hofmann, Damian Hernandez, William S. Hlavacek, Jianjun Huang, Tomasz Jetka, Dongya Jia, Mohit Kumar Jolly, Boris N. Kholodenko, Markek Kimmel, Michał Komorowski, Ganhui Lan, Heeseob Lee, Herbert Levine, Leslie M Loew, Jason G. Lomnitz, Ard A. Louis, Grant Lythe, Carmen Molina-París, Ion I. Moraru, Andrew Mugler, Brian Munsky, Joe Natale, Ilya Nemenman, Karol Nienałtowski, Marco S. Nobile, Maria Nowicka, Sarah Olson, Alan S. Perelson, Linda R. Petzold, Sreenivasan Ponnambalam, Arya Pourzanjani, Ruy M. Ribeiro, William Raymond, William Raymond, Herbert M. Sauro, Michael A. Savageau, Abhyudai Singh, James C. Schaff, Boris M. Slepchenko, Thomas R. Sokolowski, Petr Šulc, Andrea Tangherloni, Pieter Rein ten Wolde, Philipp Thomas, Karen Tkach Tuzman, Lev S. Tsimring, Dan Vasilescu, Margaritis Voliotis, Lisa Weber

The Role of Theory in Advancing 21st-Century Biology

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Publisher : National Academies Press
ISBN 13 : 030913417X
Total Pages : 208 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Role of Theory in Advancing 21st-Century Biology by : National Research Council

Download or read book The Role of Theory in Advancing 21st-Century Biology written by National Research Council and published by National Academies Press. This book was released on 2008-01-22 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although its importance is not always recognized, theory is an integral part of all biological research. Biologists' theoretical and conceptual frameworks inform every step of their research, affecting what experiments they do, what techniques and technologies they develop and use, and how they interpret their data. By examining how theory can help biologists answer questions like "What are the engineering principles of life?" or "How do cells really work?" the report shows how theory synthesizes biological knowledge from the molecular level to the level of whole ecosystems. The book concludes that theory is already an inextricable thread running throughout the practice of biology; but that explicitly giving theory equal status with other components of biological research could help catalyze transformative research that will lead to creative, dynamic, and innovative advances in our understanding of life.

An Introduction to Systems Biology

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Publisher : CRC Press
ISBN 13 : 142001143X
Total Pages : 320 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis An Introduction to Systems Biology by : Uri Alon

Download or read book An Introduction to Systems Biology written by Uri Alon and published by CRC Press. This book was released on 2006-07-07 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thorough and accessible, this book presents the design principles of biological systems, and highlights the recurring circuit elements that make up biological networks. It provides a simple mathematical framework which can be used to understand and even design biological circuits. The textavoids specialist terms, focusing instead on several well-studied biological systems that concisely demonstrate key principles. An Introduction to Systems Biology: Design Principles of Biological Circuits builds a solid foundation for the intuitive understanding of general principles. It encourages the reader to ask why a system is designed in a particular way and then proceeds to answer with simplified models.

The Life Organic

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Publisher : University of Pittsburgh Press
ISBN 13 : 082298198X
Total Pages : 328 pages
Book Rating : 4.8/5 (229 download)

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Book Synopsis The Life Organic by : Erik L. Peterson

Download or read book The Life Organic written by Erik L. Peterson and published by University of Pittsburgh Press. This book was released on 2017-02-10 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: As scientists debated the nature of life in the nineteenth century, two theories predominated: vitalism, which suggested that living things contained a “vital spark,” and mechanism, the idea that animals and humans differed from nonliving things only in their degree of complexity. Erik Peterson tells the forgotten story of the pursuit of a “third way’ in biology, known by many names, including “the organic philosophy,” which gave rise to C. H. Waddington’s work in the subfield of epigenetics: an alternative to standard genetics and evolutionary biology that captured the attention of notable scientists from Francis Crick to Stephen Jay Gould. The Life Organic chronicles the influential biologists, mathematicians, philosophers, and biochemists from both sides of the Atlantic who formed Joseph Needham’s Theoretical Biology Club, defined and refined “third way” thinking through the 1930s, and laid the groundwork for some of the most cutting-edge achievements in biology today. By tracing the persistence of organicism into the twenty-first century, this book also raises significant questions about how we should model the development of the discipline of biology going forward.

Theoretical Biology

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Publisher :
ISBN 13 : 9780801845192
Total Pages : 0 pages
Book Rating : 4.8/5 (451 download)

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Book Synopsis Theoretical Biology by : Brian C. Goodwin

Download or read book Theoretical Biology written by Brian C. Goodwin and published by . This book was released on 1992 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: How does complexity of development, structure, and function of organisms emerge from the relative simplicity of biochemistry and genetics? In Theoretical Biology, Brian Goodwin and Peter Saunders bring together a distinguished group of contributors to provide a broad-based yet coherent inquiry into biological processes. In the spirit of C. H. Waddington's Towards a Theoretical Biology, the authors seek to establish the generative principles that apply throughout the field of biology to give a unifying logical structure to diverse empirical phenomena. Major topics include self-organization in complex systems; order and adaptability in genetic networks; development and evolution; and the relevance of physics and mathematics to biology.

The Routledge Companion to Biology in Art and Architecture

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Publisher : Routledge
ISBN 13 : 1317419502
Total Pages : 761 pages
Book Rating : 4.3/5 (174 download)

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Book Synopsis The Routledge Companion to Biology in Art and Architecture by : Charissa Terranova

Download or read book The Routledge Companion to Biology in Art and Architecture written by Charissa Terranova and published by Routledge. This book was released on 2016-08-12 with total page 761 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Routledge Companion to Biology in Art and Architecture collects thirty essays from a transdisciplinary array of experts on biology in art and architecture. The book presents a diversity of hybrid art-and-science thinking, revealing how science and culture are interwoven. The book situates bioart and bioarchitecture within an expanded field of biology in art, architecture, and design. It proposes an emergent field of biocreativity and outlines its historical and theoretical foundations from the perspective of artists, architects, designers, scientists, historians, and theoreticians. Includes over 150 black and white images.

Theoretical Biology

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Publisher :
ISBN 13 :
Total Pages : 400 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis Theoretical Biology by : Jakob von Uexküll

Download or read book Theoretical Biology written by Jakob von Uexküll and published by . This book was released on 1926 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Levels of Organization in the Biological Sciences

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Publisher : MIT Press
ISBN 13 : 0262362252
Total Pages : 337 pages
Book Rating : 4.2/5 (623 download)

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Book Synopsis Levels of Organization in the Biological Sciences by : Daniel S. Brooks

Download or read book Levels of Organization in the Biological Sciences written by Daniel S. Brooks and published by MIT Press. This book was released on 2021-08-24 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific philosophers examine the nature and significance of levels of organization, a core structural principle in the biological sciences. This volume examines the idea of levels of organization as a distinct object of investigation, considering its merits as a core organizational principle for the scientific image of the natural world. It approaches levels of organization--roughly, the idea that the natural world is segregated into part-whole relationships of increasing spatiotemporal scale and complexity--in terms of its roles in scientific reasoning as a dynamic, open-ended idea capable of performing multiple overlapping functions in distinct empirical settings. The contributors--scientific philosophers with longstanding ties to the biological sciences--discuss topics including the philosophical and scientific contexts for an inquiry into levels; whether the concept can actually deliver on its organizational promises; the role of levels in the development and evolution of complex systems; conditional independence and downward causation; and the extension of the concept into the sociocultural realm. Taken together, the contributions embrace the diverse usages of the term as aspects of the big picture of levels of organization. Contributors Jan Baedke, Robert W. Batterman, Daniel S. Brooks, James DiFrisco, Markus I. Eronen, Carl Gillett, Sara Green, James Griesemer, Alan C. Love, Angela Potochnik, Thomas Reydon, Ilya Tëmkin, Jon Umerez, William C. Wimsatt, James Woodward

Origination of Organismal Form

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Publisher : MIT Press
ISBN 13 : 9780262134194
Total Pages : 354 pages
Book Rating : 4.1/5 (341 download)

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Book Synopsis Origination of Organismal Form by : Gerd B. Muller

Download or read book Origination of Organismal Form written by Gerd B. Muller and published by MIT Press. This book was released on 2003-01-03 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: A more comprehensive version of evolutionary theory that focuses as much on the origin of biological form as on its diversification. The field of evolutionary biology arose from the desire to understand the origin and diversity of biological forms. In recent years, however, evolutionary genetics, with its focus on the modification and inheritance of presumed genetic programs, has all but overwhelmed other aspects of evolutionary biology. This has led to the neglect of the study of the generative origins of biological form. Drawing on work from developmental biology, paleontology, developmental and population genetics, cancer research, physics, and theoretical biology, this book explores the multiple factors responsible for the origination of biological form. It examines the essential problems of morphological evolution—why, for example, the basic body plans of nearly all metazoans arose within a relatively short time span, why similar morphological design motifs appear in phylogenetically independent lineages, and how new structural elements are added to the body plan of a given phylogenetic lineage. It also examines discordances between genetic and phenotypic change, the physical determinants of morphogenesis, and the role of epigenetic processes in evolution. The book discusses these and other topics within the framework of evolutionary developmental biology, a new research agenda that concerns the interaction of development and evolution in the generation of biological form. By placing epigenetic processes, rather than gene sequence and gene expression changes, at the center of morphological origination, this book points the way to a more comprehensive theory of evolution.

Theoretical Morphology

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Publisher : Columbia University Press
ISBN 13 : 9780231106160
Total Pages : 332 pages
Book Rating : 4.1/5 (61 download)

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Book Synopsis Theoretical Morphology by : George R. McGhee

Download or read book Theoretical Morphology written by George R. McGhee and published by Columbia University Press. This book was released on 1999 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: McGhee describes the steps involved in defining the geometric parameters (theoretical morphospaces) for an organic form in order to generate a spectrum of other possible forms that have never actually appeared. The book also addresses the simulation of actual processes of morphogenesis, with the goal of attaining a more nuanced comprehension of how evolutionary processes work. The book covers theoretical morphospaces, including those for univalved, bivalved, discrete, and branching growth systems.

A Biologist's Guide to Mathematical Modeling in Ecology and Evolution

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Publisher : Princeton University Press
ISBN 13 : 1400840910
Total Pages : 745 pages
Book Rating : 4.4/5 (8 download)

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Book Synopsis A Biologist's Guide to Mathematical Modeling in Ecology and Evolution by : Sarah P. Otto

Download or read book A Biologist's Guide to Mathematical Modeling in Ecology and Evolution written by Sarah P. Otto and published by Princeton University Press. This book was released on 2011-09-19 with total page 745 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thirty years ago, biologists could get by with a rudimentary grasp of mathematics and modeling. Not so today. In seeking to answer fundamental questions about how biological systems function and change over time, the modern biologist is as likely to rely on sophisticated mathematical and computer-based models as traditional fieldwork. In this book, Sarah Otto and Troy Day provide biology students with the tools necessary to both interpret models and to build their own. The book starts at an elementary level of mathematical modeling, assuming that the reader has had high school mathematics and first-year calculus. Otto and Day then gradually build in depth and complexity, from classic models in ecology and evolution to more intricate class-structured and probabilistic models. The authors provide primers with instructive exercises to introduce readers to the more advanced subjects of linear algebra and probability theory. Through examples, they describe how models have been used to understand such topics as the spread of HIV, chaos, the age structure of a country, speciation, and extinction. Ecologists and evolutionary biologists today need enough mathematical training to be able to assess the power and limits of biological models and to develop theories and models themselves. This innovative book will be an indispensable guide to the world of mathematical models for the next generation of biologists. A how-to guide for developing new mathematical models in biology Provides step-by-step recipes for constructing and analyzing models Interesting biological applications Explores classical models in ecology and evolution Questions at the end of every chapter Primers cover important mathematical topics Exercises with answers Appendixes summarize useful rules Labs and advanced material available

Multicellularity

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Publisher : MIT Press
ISBN 13 : 0262333759
Total Pages : 329 pages
Book Rating : 4.2/5 (623 download)

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Book Synopsis Multicellularity by : Karl J. Niklas

Download or read book Multicellularity written by Karl J. Niklas and published by MIT Press. This book was released on 2016-02-19 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scholars consider the origins and consequences of the evolution of multicellularity, addressing a range of organisms, experimental protocols, theoretical concepts, and philosophical issues. The evolution of multicellularity raises questions regarding genomic and developmental commonalities and discordances, selective advantages and disadvantages, physical determinants of development, and the origins of morphological novelties. It also represents a change in the definition of individuality, because a new organism emerges from interactions among single cells. This volume considers these and other questions, with contributions that explore the origins and consequences of the evolution of multicellularity, addressing a range of topics, organisms, and experimental protocols. Each section focuses on selected topics or particular lineages that present a significant insight or challenge. The contributors consider the fossil record of the paleontological circumstances in which animal multicellularity evolved; cooptation, recurrent patterns, modularity, and plausible pathways for multicellular evolution in plants; theoretical approaches to the amoebozoa and fungi (cellular slime molds having long provided a robust model system for exploring the evolution of multicellularity), plants, and animals; genomic toolkits of metazoan multicellularity; and philosophical aspects of the meaning of individuality in light of multicellular evolution. Contributors Maja Adamska, Argyris Arnellos, Juan A. Arias, Eugenio Azpeitia, Mariana Benítez, Adriano Bonforti, John Tyler Bonner, Peter L. Conlin, A. Keith Dunker, Salva Duran-Nebreda, Ana E. Escalante, Valeria Hernández-Hernández, Kunihiko Kaneko, Andrew H. Knoll, Stephan G. König, Daniel J. G. Lahr, Ottoline Leyser, Alan C. Love, Raul Montañez, Emilio Mora van Cauwelaert, Alvaro Moreno, Vidyanand Nanjundiah, Aurora M. Nedelcu, Stuart A. Newman, Karl J. Niklas, William C. Ratcliff, Iñaki Ruiz-Trillo, Ricard Solé

Evolutionary Causation

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Publisher : MIT Press
ISBN 13 : 0262039923
Total Pages : 361 pages
Book Rating : 4.2/5 (62 download)

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Book Synopsis Evolutionary Causation by : Tobias Uller

Download or read book Evolutionary Causation written by Tobias Uller and published by MIT Press. This book was released on 2019-09-03 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive treatment of the concept of causation in evolutionary biology that makes clear its central role in both historical and contemporary debates. Most scientific explanations are causal. This is certainly the case in evolutionary biology, which seeks to explain the diversity of life and the adaptive fit between organisms and their surroundings. The nature of causation in evolutionary biology, however, is contentious. How causation is understood shapes the structure of evolutionary theory, and historical and contemporary debates in evolutionary biology have revolved around the nature of causation. Despite its centrality, and differing views on the subject, the major conceptual issues regarding the nature of causation in evolutionary biology are rarely addressed. This volume fills the gap, bringing together biologists and philosophers to offer a comprehensive, interdisciplinary treatment of evolutionary causation. Contributors first address biological motivations for rethinking evolutionary causation, considering the ways in which development, extra-genetic inheritance, and niche construction challenge notions of cause and process in evolution, and describing how alternative representations of evolutionary causation can shed light on a range of evolutionary problems. Contributors then analyze evolutionary causation from a philosophical perspective, considering such topics as causal entanglement, the commingling of organism and environment, and the relationship between causation and information. Contributors John A. Baker, Lynn Chiu, David I. Dayan, Renée A. Duckworth, Marcus W Feldman, Susan A. Foster, Melissa A. Graham, Heikki Helanterä, Kevin N. Laland, Armin P. Moczek, John Odling-Smee, Jun Otsuka, Massimo Pigliucci, Arnaud Pocheville, Arlin Stoltzfus, Karola Stotz, Sonia E. Sultan, Christoph Thies, Tobias Uller, Denis M. Walsh, Richard A. Watson

Routledge Handbook of Art, Science, and Technology Studies

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Publisher : Routledge
ISBN 13 : 0429792832
Total Pages : 952 pages
Book Rating : 4.4/5 (297 download)

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Book Synopsis Routledge Handbook of Art, Science, and Technology Studies by : Hannah Star Rogers

Download or read book Routledge Handbook of Art, Science, and Technology Studies written by Hannah Star Rogers and published by Routledge. This book was released on 2021-12-22 with total page 952 pages. Available in PDF, EPUB and Kindle. Book excerpt: Art and science work is experiencing a dramatic rise coincident with burgeoning Science and Technology Studies (STS) interest in this area. Science has played the role of muse for the arts, inspiring imaginative reconfigurations of scientific themes and exploring their cultural resonance. Conversely, the arts are often deployed in the service of science communication, illustration, and popularization. STS scholars have sought to resist the instrumentalization of the arts by the sciences, emphasizing studies of theories and practices across disciplines and the distinctive and complementary contributions of each. The manifestation of this commonality of creative and epistemic practices is the emergence of Art, Science, and Technology Studies (ASTS) as the interdisciplinary exploration of art–science. This handbook defines the modes, practices, crucial literature, and research interests of this emerging field. It explores the questions, methodologies, and theoretical implications of scholarship and practice that arise at the intersection of art and STS. Further, ASTS demonstrates how the arts are intervening in STS. Drawing on methods and concepts derived from STS and allied fields including visual studies, performance studies, design studies, science communication, and aesthetics and the knowledge of practicing artists and curators, ASTS is predicated on the capacity to see both art and science as constructions of human knowledge- making. Accordingly, it posits a new analytical vernacular, enabling new ways of seeing, understanding, and thinking critically about the world. This handbook provides scholars and practitioners already familiar with the themes and tensions of art–science with a means of connecting across disciplines. It proposes organizing principles for thinking about art–science across the sciences, social sciences, humanities, and arts. Encounters with art and science become meaningful in relation to practices and materials manifest as perceptual habits, background knowledge, and cultural norms. As the chapters in this handbook demonstrate, a variety of STS tools can be brought to bear on art–science so that systematic research can be conducted on this unique set of knowledge-making practices.

Convergent Evolution

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Publisher : MIT Press
ISBN 13 : 0262539098
Total Pages : 335 pages
Book Rating : 4.2/5 (625 download)

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Book Synopsis Convergent Evolution by : George R. McGhee, Jr.

Download or read book Convergent Evolution written by George R. McGhee, Jr. and published by MIT Press. This book was released on 2011-11-04 with total page 335 pages. Available in PDF, EPUB and Kindle. Book excerpt: An analysis of convergent evolution from molecules to ecosystems, demonstrating the limited number of evolutionary pathways available to life. Charles Darwin famously concluded On the Origin of Species with a vision of “endless forms most beautiful” continually evolving. More than 150 years later many evolutionary biologists see not endless forms but the same, or very similar, forms evolving repeatedly in many independent species lineages. A porpoise's fishlike fins, for example, are not inherited from fish ancestors but are independently derived convergent traits. In this book, George McGhee describes the ubiquity of the phenomenon of convergent evolution and connects it directly to the concept of evolutionary constraint—the idea that the number of evolutionary pathways available to life are not endless, but quite limited. Convergent evolution occurs on all levels, from tiny organic molecules to entire ecosystems of species. McGhee demonstrates its ubiquity in animals, both herbivore and carnivore; in plants; in ecosystems; in molecules, including DNA, proteins, and enzymes; and even in minds, describing problem-solving behavior and group behavior as the products of convergence. For each species example, he provides an abbreviated list of the major nodes in its phylogenetic classification, allowing the reader to see the evolutionary relationship of a group of species that have independently evolved a similar trait by convergent evolution. McGhee analyzes the role of functional and developmental constraints in producing convergent evolution, and considers the scientific and philosophical implications of convergent evolution for the predictability of the evolutionary process.

The Major Transitions in Evolution Revisited

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Publisher : MIT Press
ISBN 13 : 0262294532
Total Pages : 330 pages
Book Rating : 4.2/5 (622 download)

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Book Synopsis The Major Transitions in Evolution Revisited by : Brett Calcott

Download or read book The Major Transitions in Evolution Revisited written by Brett Calcott and published by MIT Press. This book was released on 2011-04-22 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drawing on recent advances in evolutionary biology, prominent scholars return to the question posed in a pathbreaking book: how evolution itself evolved. In 1995, John Maynard Smith and Eörs Szathmáry published their influential book The Major Transitions in Evolution. The "transitions" that Maynard Smith and Szathmáry chose to describe all constituted major changes in the kinds of organisms that existed but, most important, these events also transformed the evolutionary process itself. The evolution of new levels of biological organization, such as chromosomes, cells, multicelled organisms, and complex social groups radically changed the kinds of individuals natural selection could act upon. Many of these events also produced revolutionary changes in the process of inheritance, by expanding the range and fidelity of transmission, establishing new inheritance channels, and developing more open-ended sources of variation. Maynard Smith and Szathmáry had planned a major revision of their work, but the death of Maynard Smith in 2004 prevented this. In this volume, prominent scholars (including Szathmáry himself) reconsider and extend the earlier book's themes in light of recent developments in evolutionary biology. The contributors discuss different frameworks for understanding macroevolution, prokaryote evolution (the study of which has been aided by developments in molecular biology), and the complex evolution of multicellularity.