The Application of Novel Positron Emission Tomography (PET) Radioligands as Imaging Biomarkers of Neurochemical Changes in the Brain

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ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (13 download)

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Book Synopsis The Application of Novel Positron Emission Tomography (PET) Radioligands as Imaging Biomarkers of Neurochemical Changes in the Brain by : Ivonne Suridjan

Download or read book The Application of Novel Positron Emission Tomography (PET) Radioligands as Imaging Biomarkers of Neurochemical Changes in the Brain written by Ivonne Suridjan and published by . This book was released on 2014 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Quantitative Functional Brain Imaging with Positron Emission Tomography

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Publisher : Elsevier
ISBN 13 : 0080540112
Total Pages : 535 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Quantitative Functional Brain Imaging with Positron Emission Tomography by : Richard E. Carson

Download or read book Quantitative Functional Brain Imaging with Positron Emission Tomography written by Richard E. Carson and published by Elsevier. This book was released on 1998-09-08 with total page 535 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the latest scientific developments in the field of positron emission tomography (PET) dealing with data acquisition, image processing, applications, statistical analysis, tracer development, parameter estimation, and kinetic modeling. It covers improved methodology and the application of existing techniques to new areas. The text also describes new approaches in scanner design and image processing, and the latest techniques for modeling and statistical analyses. This volume will be a useful reference for the active brain PET scientist, as well as a valuable introduction for students and researchers who wish to take advantage of the capabilities of PET to study the normal and diseased brain. Authored by international authorities in PET Provides the latest up-to-date techniques and applications Covers all fundamental disciplines of PET in one volume A comprehensive resource for students, clinicians, and new PET researchers

Brain Imaging Using PET

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Publisher : Gulf Professional Publishing
ISBN 13 : 9780126366518
Total Pages : 356 pages
Book Rating : 4.3/5 (665 download)

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Book Synopsis Brain Imaging Using PET by : Michio Senda

Download or read book Brain Imaging Using PET written by Michio Senda and published by Gulf Professional Publishing. This book was released on 2002 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discusses PET technique and instrumentation, as well as developments in a range of fields such as kinetics, enzyme/neurotransmitter transport, language acquisition, and neuropathology. This title offers an analysis of brain imaging and techniques, from the foundations to the practical applications of the modern techniques used in PET.

Brain Imaging in Behavioral Neuroscience

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Publisher : Springer Science & Business Media
ISBN 13 : 3642287115
Total Pages : 395 pages
Book Rating : 4.6/5 (422 download)

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Book Synopsis Brain Imaging in Behavioral Neuroscience by : Cameron S. Carter

Download or read book Brain Imaging in Behavioral Neuroscience written by Cameron S. Carter and published by Springer Science & Business Media. This book was released on 2011-11-04 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume highlights the remarkable new developments in brain imaging, including those that apply magnetic resonance imaging (MRI) and Positron Emission Tomography (PET), that allow us to non invasively study the living human brain in health and in disease. These technological advances have allowed us to obtain new and powerful insights into the structure and function of the healthy brain as it develops across the life cycle, as well as the molecular make up of brain systems and circuits as they develop and change with age. New brain imaging technologies have also given us new insights into the causes of many common brain disorders, including ADHD, schizophrenia, depression and Alzheimer’s disease, which collectively affect a large segment of the population. These new insights have major implications for understanding and treating these brain disorders, and are providing clinicians with the first ever set of biomarkers that can be used to guide diagnosis and monitor treatment effects. The advances in brain imaging over the last 20 years, summarized in this volume, represent a major advance in modern biomedical sciences.

Hybrid PET/MR Neuroimaging

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Publisher : Springer Nature
ISBN 13 : 3030823679
Total Pages : 848 pages
Book Rating : 4.0/5 (38 download)

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Book Synopsis Hybrid PET/MR Neuroimaging by : Ana M. Franceschi

Download or read book Hybrid PET/MR Neuroimaging written by Ana M. Franceschi and published by Springer Nature. This book was released on 2021-11-30 with total page 848 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book serves as a reference and comprehensive guide for PET/MR neuroimaging. The field of PET/MR is rapidly evolving, however, there is no standard resource summarizing the vast information and its potential applications. This book will guide neurological molecular imaging applications in both clinical practice and the research setting. Experts from multiple disciplines, including radiologists, researchers, and physicists, have collaborated to bring their knowledge and expertise together. Sections begin by covering general considerations, including public health and economic implications, the physics of PET/MR systems, an overview of hot lab and cyclotron, and radiotracers used in neurologic PET/MRI. There is then coverage of each major disease/systemic category, including dementia and neurodegenerative disease, epilepsy localization, brain tumors, inflammatory and infectious CNS disorders, head and neck imaging, as well as vascular hybrid imaging. Together, we have created a thorough, concise and up-to-date textbook in a unique, user-friendly format. This is an ideal guide for neuroradiologists, nuclear medicine specialists, medical physicists, clinical trainees and researchers.

Physiological Imaging of the Brain with PET

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Publisher : Academic Press
ISBN 13 :
Total Pages : 452 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Physiological Imaging of the Brain with PET by : Albert Gjedde

Download or read book Physiological Imaging of the Brain with PET written by Albert Gjedde and published by Academic Press. This book was released on 2001 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: Physiological Imaging of the Brain with PET provides the latest techniques and applications for PET as a tool to study the physiology of the brain, and is sponsored by the International Society of Cerebral Blood Flow and Metabolism. It covers all of the fundamental disciplines of PET in one volume. Written by international experts in brain imaging, it is a useful reference for the active brain PET scientist, and a valuable introduction to students, clinicians, and researchers who wish to take advantage of the capabilities of this technique to study the normal and diseased brain. Key Features * Provides the latest techniques and applications of positron emission tomography (PET) * Covers all fundamental disciplines of PET in one volume * Serves as a comprehensive resource for students, clinicians and new researchers

Investigation of Novel Positron Emission Tomography Radioligands for in Vivo Characterization of Alzheimer's Disease Pathophysiology

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (112 download)

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Book Synopsis Investigation of Novel Positron Emission Tomography Radioligands for in Vivo Characterization of Alzheimer's Disease Pathophysiology by : Tobey J. Betthauser

Download or read book Investigation of Novel Positron Emission Tomography Radioligands for in Vivo Characterization of Alzheimer's Disease Pathophysiology written by Tobey J. Betthauser and published by . This book was released on 2018 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Positron emission tomography (PET) has become an integral component of neurodegenerative disease research. The rapid implementation of novel PET radiopharmaceuticals into clinical research necessitates detailed characterization and optimization of the radiopharmaceutical production process, PET imaging protocol, and image processing and analysis methodology. This work details the optimization and automated production of PET radioligands [18F]THK-5351 and [18F]MK-6240, investigates methodological considerations for image processing and quantification of [18F]THK-5317, [18F]THK-5351, and [18F]MK-6240, and evaluates the application of these PET radiopharmaceuticals for human imaging neurofibrillary tangles (NFTs, a hallmark proteinopathy of Alzheimer's disease) in the context of clinical neurodegenerative disease research. In addition, dosimetric considerations and longitudinal, multi-tracer image processing and analysis pipelines are explored. Individual steps of the radiochemical synthesis, purification and formulation processes were examined and translated to automated production routines, which produce radiopharmaceuticals characterized and suitable for human research use. As part of this process, a novel purification and formulation device was designed, manufactured, and tested. PET radioligands [18F]THK-5317, [18F]THK-5351 and [18F]MK-6240 were investigated in human subjects ranging from cognitively stable controls to persons clinically diagnosed with probable AD dementia. Pharmacokinetic properties, radiotracer binding, and quantification methods and imaging protocols were explored individually for each radiotracer. Comparisons were made between radiotracers using optimized PET acquisition, processing and analysis methods. The remaining chapters investigate practical considerations for longitudinal PET studies including internal dosimetry, semi-automated processing and analysis of multimodal, multi-tracer PET and MRI neuroimaging data, and the effects of attenuation correction on longitudinal PET binding estimates. The results of this work provide a framework that facilitates large-scale, multi-tracer, multi-modal imaging investigation of the pathophysiological processes occurring in the Alzheimer's disease continuum within a longitudinal paradigm.

Imaging of the Human Brain in Health and Disease

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Publisher : Elsevier
ISBN 13 : 012418684X
Total Pages : 534 pages
Book Rating : 4.1/5 (241 download)

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Book Synopsis Imaging of the Human Brain in Health and Disease by : Philip Seeman

Download or read book Imaging of the Human Brain in Health and Disease written by Philip Seeman and published by Elsevier. This book was released on 2013-11-15 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain imaging technology remains at the forefront of advances in both our understanding of the brain and our ability to diagnose and treat brain disease and disorders. Imaging of the Human Brain in Health and Disease examines the localization of neurotransmitter receptors in the nervous system of normal, healthy humans and compares that with humans who are suffering from various neurologic diseases. Opening chapters introduce the basic science of imaging neurotransmitters, including sigma, acetylcholine, opioid, and dopamine receptors. Imaging the healthy and diseased brain includes brain imaging of anger, pain, autism, the release of dopamine, the impact of cannabinoids, and Alzheimer's disease. This book is a valuable companion to a wide range of scholars, students, and researchers in neuroscience, clinical neurology, and psychiatry, and provides a detailed introduction to the application of advanced imaging to the treatment of brain disorders and disease. A focused introduction to imaging healthy and diseased brains Focuses on the primary neurotransmitter release Includes sigma, acetylcholine, opioid, and dopamine receptors Presents the imaging of healthy and diseased brains via anger, pain, autism, and Alzheimer's disease

Positron Emission Tomography of the Brain

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Publisher :
ISBN 13 : 9789172226081
Total Pages : 39 pages
Book Rating : 4.2/5 (26 download)

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Book Synopsis Positron Emission Tomography of the Brain by : Jan-Eric Litton

Download or read book Positron Emission Tomography of the Brain written by Jan-Eric Litton and published by . This book was released on 1983 with total page 39 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Novel Imaging Techniques in Neurodegenerative and Movement Disorders, An Issue of PET Clinics

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Publisher : Elsevier Health Sciences
ISBN 13 : 032322735X
Total Pages : 110 pages
Book Rating : 4.3/5 (232 download)

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Book Synopsis Novel Imaging Techniques in Neurodegenerative and Movement Disorders, An Issue of PET Clinics by : Rathan Subramaniam

Download or read book Novel Imaging Techniques in Neurodegenerative and Movement Disorders, An Issue of PET Clinics written by Rathan Subramaniam and published by Elsevier Health Sciences. This book was released on 2013-10-15 with total page 110 pages. Available in PDF, EPUB and Kindle. Book excerpt: Edited by leaders of the field, Rathan Subramaniam from Johns Hopkins and Jorge Barrio from UCLA, this issue of PET Clinics focuses on the evolving role of novel imaging techniques in negenerative and movement disorders common in the aged population.

Neuroimaging in Psychiatry

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Publisher : CRC Press
ISBN 13 : 9781841842295
Total Pages : 288 pages
Book Rating : 4.8/5 (422 download)

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Book Synopsis Neuroimaging in Psychiatry by : Cynthia H. Y. Fu

Download or read book Neuroimaging in Psychiatry written by Cynthia H. Y. Fu and published by CRC Press. This book was released on 2003-09-26 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: New neuroimaging techniques are developing at a break neck pace-every academic journal contains glossy pictures of brain activity corresponding to a particular task emblazoned in glorious technicolor. Discoveries about brain function in psychiatric disorders have been made at an equally rapid rate. However, most books on the subject have been written from a technical point of view. An introductory, easy-to-read guide, Neuroimaging in Psychiatry provides an overview and the clinical relevance of the latest neuroimaging findings. With contributions from an international panel of experts, this book reviews current findings from neuroimaging in schizophrenia, obsessive-compulsive disorder, depression, eating disorders, psychopathy, aging, and drug addiction. Chapter authors explore innovative and imaginative uses of neuro imaging technology, implications for our understanding of these disorders, and their impact on clinical practice. The book gives you a general overview of the main techniques to help you successfully complete a neuroimaging project.

Brain Disorders in Critical Illness

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Publisher : Cambridge University Press
ISBN 13 : 1107434424
Total Pages : 457 pages
Book Rating : 4.1/5 (74 download)

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Book Synopsis Brain Disorders in Critical Illness by : Robert D. Stevens

Download or read book Brain Disorders in Critical Illness written by Robert D. Stevens and published by Cambridge University Press. This book was released on 2013-09-19 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain dysfunction is a major clinical problem in intensive care, with potentially debilitating long-term consequences for post-ICU patients of any age. The resulting extended length of stay in the ICU and post-discharge cognitive dysfunction are now recognized as major healthcare burdens. This comprehensive clinical text provides intensivists and neurologists with a practical review of the pathophysiology of brain dysfunction and a thorough account of the diagnostic and therapeutic options available. Initial sections review the epidemiology, outcomes, relevant behavioral neurology and biological mechanisms of brain dysfunction. Subsequent sections evaluate the available diagnostic options and preventative and therapeutic interventions, with a final section on clinical encephalopathy syndromes encountered in the ICU. Each chapter is rich in illustrations, with an executive summary and a helpful glossary of terms. Brain Disorders in Critical Illness is a seminal reference for all physicians and neuroscientists interested in the care and outcome of severely ill patients.

Late-Life Mood Disorders

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Publisher : Oxford University Press
ISBN 13 : 0199796815
Total Pages : 795 pages
Book Rating : 4.1/5 (997 download)

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Book Synopsis Late-Life Mood Disorders by : Helen Lavretsky

Download or read book Late-Life Mood Disorders written by Helen Lavretsky and published by Oxford University Press. This book was released on 2013-04-04 with total page 795 pages. Available in PDF, EPUB and Kindle. Book excerpt: Late-life Mood Disorders provides a comprehensive review of the current research advances in neurobiology and psychosocial origins of geriatric mood disorders. The review of the latest developments and "gold standards" of care is provided by an international group of leading experts.

Basic Science of PET Imaging

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Publisher : Springer
ISBN 13 : 3319400703
Total Pages : 621 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Basic Science of PET Imaging by : Magdy M. Khalil

Download or read book Basic Science of PET Imaging written by Magdy M. Khalil and published by Springer. This book was released on 2016-11-07 with total page 621 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a wide-ranging and up-to-date overview of the basic science underlying PET and its preclinical and clinical applications in modern medicine. In addition, it provides the reader with a sound understanding of the scientific principles and use of PET in routine practice and biomedical imaging research. The opening sections address the fundamental physics, radiation safety, CT scanning dosimetry, and dosimetry of PET radiotracers, chemistry and regulation of PET radiopharmaceuticals, with information on labeling strategies, tracer quality control, and regulation of radiopharmaceutical production in Europe and the United States. PET physics and instrumentation are then discussed, covering the basic principles of PET and PET scanning systems, hybrid PET/CT and PET/MR imaging, system calibration, acceptance testing, and quality control. Subsequent sections focus on image reconstruction, processing, and quantitation in PET and hybrid PET and on imaging artifacts and correction techniques, with particular attention to partial volume correction and motion artifacts. The book closes by examining clinical applications of PET and hybrid PET and their physiological and/or molecular basis in conjunction with technical foundations in the disciplines of oncology, cardiology and neurology, PET in pediatric malignancy and its role in radiotherapy treatment planning. Basic Science of PET Imaging will meet the needs of nuclear medicine practitioners, other radiology specialists, and trainees in these fields.

Neuroimaging of Sleep and Sleep Disorders

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Publisher : Cambridge University Press
ISBN 13 : 1107018633
Total Pages : 445 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Neuroimaging of Sleep and Sleep Disorders by : Eric Nofzinger

Download or read book Neuroimaging of Sleep and Sleep Disorders written by Eric Nofzinger and published by Cambridge University Press. This book was released on 2013-03-07 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt: An up-to-date, superbly illustrated practical guide to the effective use of neuroimaging in the patient with sleep disorders. The only book to date to provide comprehensive coverage of this topic. A must for all healthcare workers interested in understanding the causes, consequences and treatment of sleep disorders.

Neurobiology of Mental Illness

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Publisher : Oxford University Press
ISBN 13 : 9780199857548
Total Pages : 1504 pages
Book Rating : 4.8/5 (575 download)

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Book Synopsis Neurobiology of Mental Illness by : Dennis S. Charney

Download or read book Neurobiology of Mental Illness written by Dennis S. Charney and published by Oxford University Press. This book was released on 2011-05-20 with total page 1504 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a new edition of the first comprehensive text to show how the advances in molecular and cellular biology and in the basic neurosciences have brought the revolution in molecular medicine to the field of psychiatry. The book begins with a review of basic neuroscience and methods for studying neurobiology in human patients then proceeds to discussions of all major psychiatric syndromes with respect to knowledge of their etiology, pathophysiology, and treatment. Emphasis is placed on synthesizing information across numerous levels of analysis, including molecular biology and genetics, cellular physiology, neuroanatomy, neuropharmacology, and behavior, and in translating information from the basic laboratory to the clinical laboratory and finally to clinical treatment. Editors Dennis Charney and Eric Nestle, along with their six section editors and over 150 contributors, have revised and updated all 80 chapters from the previous edition and have added new chapters on topics relating to, for example, genetics, experimental therapeutics, and late-life mood disorders. Both a textbook and a reference book, Neurobiology of Mental Illness is intended for psychiatrists, neuroscientists, and upper level students.

Mood Disorders

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Publisher : Cambridge University Press
ISBN 13 : 110842712X
Total Pages : 295 pages
Book Rating : 4.1/5 (84 download)

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Book Synopsis Mood Disorders by : Sudhakar Selvaraj

Download or read book Mood Disorders written by Sudhakar Selvaraj and published by Cambridge University Press. This book was released on 2021-01-07 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offering up-to-date information on brain imaging in mood disorders, this book is an invaluable resource for mental health professionals.