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Author :
Publisher :
ISBN 13 :
Total Pages : 154 pages
Book Rating : 4.:/5 (327 download)
Download or read book The Analysis of Cannabinoids in Biological Fluids written by and published by . This book was released on 1982 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (826 download)
Download or read book The Analysis of Cannabinoids in Biological Fluids written by and published by . This book was released on 1982 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : National Institute on Drug Abuse. Division of Research
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (122 download)
Download or read book Analysis of cannabinoids in biological fluids written by National Institute on Drug Abuse. Division of Research and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : JC. Garriott
Publisher :
ISBN 13 :
Total Pages : 1 pages
Book Rating : 4.:/5 (125 download)
Download or read book A Review of The Analysis of Cannabinoids in Biological Fluids written by JC. Garriott and published by . This book was released on 1985 with total page 1 pages. Available in PDF, EPUB and Kindle. Book excerpt: NIDA Research Monograph 42 is a presentation of their second technical review on development of cannabinoid assays for detection in biological specimens, held in January 1980. In the introduction, the editor discusses the potential utility and significance of use of cannabinoid assays in humans. Whereas determination of past use of Cannabis is now a routine capability (if proper methods are used) he explains why determination of a state of intoxication is much more difficult. The analysis of whole blood and possibly breath or saliva are discussed as potential determinants of intoxication.
Author : B. L. Law
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (535 download)
Download or read book Radioammunoassay Methods for the Forensic Analysis of Cannabinoids in Biological Fluids written by B. L. Law and published by . This book was released on 1983 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Gabriel G. Nahas
Publisher : Elsevier
ISBN 13 : 1483158047
Total Pages : 798 pages
Book Rating : 4.4/5 (831 download)
Download or read book Marihuana Biological Effects written by Gabriel G. Nahas and published by Elsevier. This book was released on 2013-10-22 with total page 798 pages. Available in PDF, EPUB and Kindle. Book excerpt: Marihuana Biological Effects: Analysis, Metabolism, Cellular Responses, Reproduction and Brain contains the proceedings of the Satellite Symposium of the 7th International Congress of Pharmacology held at Paris on July 22-23, 1978. Organized into four parts, this book begins with a discussion on the quantification of cannabinoids and their metabolites in the body fluids and tissues. Part II describes the cannabinoids and cellular metabolism. Parts III and IV explain the effects of cannabis on reproduction and brain.
Author : Joe A. Vinson
Publisher :
ISBN 13 :
Total Pages : 266 pages
Book Rating : 4.3/5 (91 download)
Download or read book Cannabinoid Analysis in Physiological Fluids written by Joe A. Vinson and published by . This book was released on 1979 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher : Elsevier
ISBN 13 : 0444643427
Total Pages : 518 pages
Book Rating : 4.4/5 (446 download)
Download or read book Analysis of Cannabis written by and published by Elsevier. This book was released on 2020-08-27 with total page 518 pages. Available in PDF, EPUB and Kindle. Book excerpt: Analysis of Cannabis, Volume 91, contains a wide variety of information on the analysis of cannabis and hemp, including cannabinoids, terpenes, volatile solvents and metals. Specific chapters in this new release include the Comprehensive Analytical Testing of Cannabis and Hemp, Machine Learning Methods for Inferring Chemotype Profiles in Cannabis Sativa, Recent Analytical Methodologies and Strategic Pharmacological Applications of Cannabinoids, Analysis of Cannabinoids in Plants, Marijuana Products and Biological Tissues, LC-based (UV and MS) Analysis of Cannabinoids, Testing Cannabis Samples for Heavy Metal Contamination using Microwave Assisted Digestion and ICP-MS Techniques, Applications of GC-MS Techniques for Cannabis Analysis, and much more. Contains diverse, state-of-the-art methodologies for the analyses of cannabinoids and terpenes in a variety of matrices Analyzes different cannabis and hemp-based products Provides the expertise of leading contributors from an international board of authors
Author :
Publisher :
ISBN 13 :
Total Pages : 168 pages
Book Rating : 4.M/5 ( download)
Download or read book NIDA Research Monograph written by and published by . This book was released on 1976 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Stig Agurell
Publisher : Academic Press
ISBN 13 : 0323141986
Total Pages : 933 pages
Book Rating : 4.3/5 (231 download)
Download or read book The Cannabinoids: Chemical, Pharmacologic, and Therapeutic Aspects written by Stig Agurell and published by Academic Press. This book was released on 2012-12-02 with total page 933 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Cannabinoids: Chemical, Pharmacologic, and Therapeutic Aspects provides a comprehensive discussion of the various aspects of cannabis and its constituents. The book is organized into six sections. Section I covers the clinical aspects of cannabis including the health aspects, impact on memory function, and the characteristics and treatment of marijuana abusers. Section II on chemical aspects includes studies on the chemistry and structure-activity relationships of cannabinoids; smoking characteristics of marijuana cigarettes; and developments in cannabinoid analyses of body fluids. Section III on metabolic and pharmacokinetic aspects includes studies on the metabolism, disposition, and pharmacokinetics of delta-9-tetrahydrocannabinol (THC) in men and women; single dose kinetics of cannabidiol in man; and distribution and disposition of THC in different tissues of the rat. Section IV on reproductive aspects include studies on the effects of chronic administration of THC on the early embryonic development of mice; effects of cannabinoids on spermatogenesis in mice; and possible mechanism for the cellular effects of marijuana on male reproductive function. Section V on neuropharmacologic aspects includes studies on the discriminative stimulus properties of THC and the effects of cannabinoids on neurotransmitter receptors in the brain. Section VI on therapeutic aspects includes studies such as the possible anxiolytic effects of cannabidiol; tetrahydrocannabinol effects on extrapyramidal motor behaviors in Parkinson's disease; and the use of cannabinoids in glaucoma.
Author :
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (641 download)
Download or read book Cannabinoid Analysis in Physiological Fluids written by and published by . This book was released on 1979 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Chelsea Elyse Fort
Publisher :
ISBN 13 :
Total Pages : 156 pages
Book Rating : 4.:/5 (932 download)
Download or read book Stability of Synthetic Cannabinoids in Biological Specimens written by Chelsea Elyse Fort and published by . This book was released on 2014 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Synthetic cannabinoids, known as "spice" or "K2" among others, create an ever-changing challenge for the forensic chemist or toxicologist. The spectrum of compounds is constantly growing and evolving. Understanding the stability and degradation timelines for these under-characterized substances will be valuable for forensic chemists across the globe as they endeavor to manage their case loads. The focus of this study was to determine the stability of four specific synthetic cannabinoids, XLR-11, UR-144, AB-Pinaca, and AB-Fubinaca. The study used human blood spiked with the compounds of interest to mimic real forensic laboratory samples submitted for synthetic cannabinoid analysis. These whole blood samples were stored under three different temperature conditions, room or ambient temperature (22°C), refrigerator temperature (4°C), and freezer conditions (-20°C). Scheduled testing on days 0, 3, 7, 14, 21, 28, 35, 42, 56, 70, and 84 were spanned the study's nearly three month duration, monitoring stability and degradation of the analytes spiked into whole blood samples. Whole blood samples were then extracted using a forward alkaline extraction at pH 10.2 and analyzed using a liquid chromatograph tandem mass spectrometer (LC-MS/MS). Results showed that AB-Fubinaca, AB-Pinaca, and UR-144 were relatively stable, while XLR-11 significantly degraded at ambient and refrigerated conditions. Frozen storage conditions were the only tested parameter able to preserve and stabilize all four compounds over the three month period. Therefore, it should be suggested that forensic blood evidence suspected of containing synthetic cannabinoid compounds should be stored in frozen conditions."--Abstract.
Author : Paul J. Bryant
Publisher :
ISBN 13 :
Total Pages : 38 pages
Book Rating : 4.3/5 (91 download)
Download or read book The Development of Technology for Detection of Marijuana Intoxication by Analysis of Body Fluids. Final Report written by Paul J. Bryant and published by . This book was released on 1975 with total page 38 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Mahmoud A. ElSohly
Publisher : Springer Science & Business Media
ISBN 13 : 1592599478
Total Pages : 323 pages
Book Rating : 4.5/5 (925 download)
Download or read book Marijuana and the Cannabinoids written by Mahmoud A. ElSohly and published by Springer Science & Business Media. This book was released on 2007-11-15 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although primarily used today as one of the most prevalent illicit leisure drugs, the use of Cannabis sativa L., commonly referred to as marijuana, for medicinal purposes has been reported for more than 5000 years. Marijuana use has been shown to create numerous health problems, and, consequently, the expanding use beyond medical purposes into recreational use (abuse) resulted in control of the drug through international treaties. Much research has been carried out over the past few decades following the identification of the chemical structure of THC in 1964. The purpose of Marijuana and the Cannabinoids is to present in a single volume the comprehensive knowledge and experience of renowned researchers and scientists. Each chapter is written independently by an expert in his/her field of endeavor, ranging from the botany, the constituents, the chemistry and pharmacokinetics, the effects and consequences of illicit use on the human body, to the therapeutic potential of the cannabinoids.
Author : Joseph A. Vinson
Publisher :
ISBN 13 : 9780608030876
Total Pages : 251 pages
Book Rating : 4.0/5 (38 download)
Download or read book Cannabinoid Analysis in Physiological Fluids written by Joseph A. Vinson and published by . This book was released on 1979-01-01 with total page 251 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Kevin D. Carrera
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.3/5 (776 download)
Download or read book Method Optimization for the Determination of Cannabinoids in Blood by Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS) written by Kevin D. Carrera and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Delta-9-tetrahydrocannabinol (THC) continues to be one of the most popular drugs in the USA. Along with THC, other cannabinoids such as cannabidiol (CBD), are on the rise due to an increase in medicinal usage as well as the passage of different legislations removing these products from their current schedule I status. Thus, an urgency exists to develop robust and sensitive analytical methods to determine cannabinoids, especially THC, CBD and metabolites, in biological samples. The purpose of this study was to investigate different analytical procedures to determine the best method to identify and quantify CBD, THC and their metabolites in whole blood by liquid chromatography tandem mass spectrometry (LC-MS/MS). In LC-MS/MS, we found that most cannabinoids worked better in electrospray (ESI) under negative mode except THC, which showed higher intensity under positive mode. Regarding extraction procedures, we optimized four different methods including liquid-liquid extraction (LLE), supported-liquid extraction (SLE), solid phase extraction (SPE) and QuEChERS. The optimal LLE employed hexane:ethyl acetate (70:30) as extraction solvent; the optimal SLE eluted the samples with dichloromethane and hexane; and the optimal SPE procedure employed mixed mode cation exchange cartridges. The procedure that yielded the best process efficiency was LLE (28.5-121.2%), and the poorest was QuEChERS (7.3-27.5%). Although the evaluated methods showed different matrix effect, extraction efficiency and process efficiency, all of them were able to achieve low limits of quantification (LOQs) between 0.5 and 5 ng/mL. Compared to currently published literature, the present methods were more sensitive in identifying THC-COOH and CBD metabolites in blood with LOQs of 0.5 ng/mL.
Author : Barry Levine
Publisher : Amer. Assoc. for Clinical Chemistry
ISBN 13 : 9781890883874
Total Pages : 406 pages
Book Rating : 4.8/5 (838 download)
Download or read book Principles of Forensic Toxicology written by Barry Levine and published by Amer. Assoc. for Clinical Chemistry. This book was released on 2003 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt:
