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Author : Per Nylén
Publisher : Nordic Council of Ministers
ISBN 13 : 9789289305310
Total Pages : 188 pages
Book Rating : 4.3/5 (53 download)
Download or read book Test Method Development on Neurotoxicity written by Per Nylén and published by Nordic Council of Ministers. This book was released on 2000 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : OECD
Publisher : OECD Publishing
ISBN 13 : 9264067396
Total Pages : 26 pages
Book Rating : 4.2/5 (64 download)
Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 426: Developmental Neurotoxicity Study written by OECD and published by OECD Publishing. This book was released on 2007-10-15 with total page 26 pages. Available in PDF, EPUB and Kindle. Book excerpt: A developmental neurotoxicity study will provide information on the effects of repeated exposure to a substance during in utero and early postnatal development. The test substance is administered daily, generally orally, to mated females (rats are ...
Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309040477
Total Pages : 449 pages
Book Rating : 4.3/5 (9 download)
Download or read book Behavioral Measures of Neurotoxicity written by National Research Council and published by National Academies Press. This book was released on 1990-02-01 with total page 449 pages. Available in PDF, EPUB and Kindle. Book excerpt: Exposure to toxic chemicalsâ€"in the workplace and at homeâ€"is increasing every day. Human behavior can be affected by such exposure and can give important clues that a person or population is in danger. If we can understand the mechanisms of these changes, we can develop better ways of testing for toxic chemical exposure and, most important, better prevention programs. This volume explores the emerging field of neurobehavioral toxicology and the potential of behavior studies as a noninvasive and economical means for risk assessment and monitoring. Pioneers in this field explore its promise for detecting environmental toxins, protecting us from exposure, and treating those who are exposed.
Author : Lucio G. Costa
Publisher : Humana Press
ISBN 13 : 9781617791710
Total Pages : 415 pages
Book Rating : 4.7/5 (917 download)
Download or read book In Vitro Neurotoxicology written by Lucio G. Costa and published by Humana Press. This book was released on 2011-08-09 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, the need to develop acceptable alternatives to conventional animal testing for neurotoxicity and developmental neurotoxicity has been increasingly recognized, and much effort is being directed toward the development of alternative models, utilizing mostly mammalian cells in culture but also non-mammalian model systems. In Vitro Neurotoxicology: Methods and Protocols presents a series of cellular, biochemical, and molecular methodological protocols in the area of in vitro neurotoxicology, with an emphasis on mammalian cell culture systems. Opening with a section on methodologies for preparing several cellular systems of variable complexity, amenable for in vitro neurotoxicological studies, the thorough volume continues with coverage of methods to measure cellular death and major mechanisms, methods for assessing mechanisms of nervous system cell toxicity related to impairment of cell signaling, while a final section illustrates additional methods for assessing important nervous system processes such as cell proliferation, neuritogenesis, and synaptogenesis. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective subjects, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, In Vitro Neurotoxicology: Methods and Protocols serves researchers with an interest in assessing or characterizing the potential neurotoxicity of environmental contaminants, drugs, or other chemicals.
Author :
Publisher : DIANE Publishing
ISBN 13 : 1428921974
Total Pages : 362 pages
Book Rating : 4.4/5 (289 download)
Download or read book Neurotoxicity : identifying and controlling poisons of the nervous system : new developments in neuroscience. written by and published by DIANE Publishing. This book was released on with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Kimmo Louekari
Publisher : Nordic Council of Ministers
ISBN 13 : 9789291209088
Total Pages : 178 pages
Book Rating : 4.2/5 (9 download)
Download or read book Nordic Toxicological and Ecotoxicological Laboratories written by Kimmo Louekari and published by Nordic Council of Ministers. This book was released on 1996 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nordic Toxicological and Ecotoxicological Laboratories
Author : United States. Congress. House. Committee on Appropriations. Subcommittee on VA, HUD, and Independent Agencies
Publisher :
ISBN 13 :
Total Pages : 1414 pages
Book Rating : 4.F/5 ( download)
Download or read book Departments of Veterans Affairs and Housing and Urban Development, and Independent Agencies Appropriations for 1994 written by United States. Congress. House. Committee on Appropriations. Subcommittee on VA, HUD, and Independent Agencies and published by . This book was released on 1993 with total page 1414 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher : Elsevier
ISBN 13 : 0080468845
Total Pages : 6448 pages
Book Rating : 4.0/5 (84 download)
Download or read book Comprehensive Toxicology written by and published by Elsevier. This book was released on 2010-06-01 with total page 6448 pages. Available in PDF, EPUB and Kindle. Book excerpt: An explosive increase in the knowledge of the effects of chemical and physical agents on biological systems has led to an increased understanding of normal cellular functions and the consequences of their perturbations. The 14-volume Second Edition of Comprehensive Toxicology has been revised and updated to reflect new advances in toxicology research, including content by some of the leading researchers in the field. It remains the premier resource for toxicologists in academia, medicine, and corporations. Comprehensive Toxicology Second Edition provides a unique organ-systems structure that allows the user to explore the toxic effects of various substances on each human system, aiding in providing diagnoses and proving essential in situations where the toxic substance is unknown but its effects on a system are obvious. Comprehensive Toxicology Second Edition is the most complete and valuable toxicology work available to researchers today. Contents updated and revised to reflect developments in toxicology research Organized with a unique organ-system approach Features full color throughout Available electronically on sciencedirect.com, as well as in a limited-edition print version
Author : Eula Bingham
Publisher : John Wiley & Sons
ISBN 13 : 0470410817
Total Pages : 5872 pages
Book Rating : 4.4/5 (74 download)
Download or read book Patty's Toxicology, 6 Volume Set written by Eula Bingham and published by John Wiley & Sons. This book was released on 2012-07-31 with total page 5872 pages. Available in PDF, EPUB and Kindle. Book excerpt: Featuring the improved format used in the 5th edition, this updated set presents, in logical groupings, comprehensive toxicological data for industrial compounds, including CAS numbers, physical and chemical properties, exposure limits, and biological tolerance values for occupational exposures, making it essential for toxicologists and industrial hygienists. This edition has about 40% new authors who have brought a new and international perspective to interpreting industrial toxicology, and discusses new subjects such as nanotechnology, flavorings and the food industry, reactive chemical control to comprehensive chemical policy, metalworking fluids, and pharmaceuticals.
Author :
Publisher :
ISBN 13 :
Total Pages : 494 pages
Book Rating : 4.:/5 (334 download)
Download or read book Code of Federal Regulations written by and published by . This book was released on 1998 with total page 494 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 :
Total Pages : 628 pages
Book Rating : 4.F/5 ( download)
Download or read book The Code of Federal Regulations of the United States of America written by and published by . This book was released on 2001 with total page 628 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Code of Federal Regulations is the codification of the general and permanent rules published in the Federal Register by the executive departments and agencies of the Federal Government.
Author : Ramesh C Gupta
Publisher : Academic Press
ISBN 13 : 0323915604
Total Pages : 1558 pages
Book Rating : 4.3/5 (239 download)
Download or read book Reproductive and Developmental Toxicology written by Ramesh C Gupta and published by Academic Press. This book was released on 2022-02-11 with total page 1558 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reproductive and Developmental Toxicology, Third Edition is a comprehensive and authoritative resource, providing the latest literature on this complex subject by focusing on three core components - parent, placenta and fetus - and the continuous changes that occur in each. Enriched with relevant references describing every aspect of reproductive toxicology, this revised and updated resource addresses the totality of the subject, discussing a broad range of topics including nanoparticles and radiation, gases and solvents, smoking, alcohol and drugs of abuse, and metals, among others. In addition, it is the only resource to include reproductive and developmental toxicity in domestic animals, fish and wildlife With a special focus on placental toxicity, this book is the only available reference to connect the three key risk stages. Completely revised and updated to include the most recent developments in the field, this book is an essential resource for advanced students and researchers in toxicology, as well as biologists, pharmacologists and teratologists from academia, industry and regulatory agencies. Provides a complete, up-to-date, integrated source of information on the key risk stages during reproduction and development Offers diverse and unique in vitro and in vivo toxicity models for reproductive and developmental toxicity testing in a user-friendly format that assists in comparative analysis Includes new chapters on developments in systems toxicology and predictive modeling of male developmental toxicity, adverse outcome pathways in reproductive and developmental toxicology, ovarian and endometrial toxicity, developmental neurotoxicity of air pollution, and more
Author : Ronald D. Hood
Publisher : CRC Press
ISBN 13 : 9780849301353
Total Pages : 794 pages
Book Rating : 4.3/5 (13 download)
Download or read book Handbook of Developmental Toxicology written by Ronald D. Hood and published by CRC Press. This book was released on 1996-10-23 with total page 794 pages. Available in PDF, EPUB and Kindle. Book excerpt: Developmental toxicology, an increasingly important area, encompasses the study of toxicant effects on development, from conception through puberty. The Handbook of Developmental Toxicology provides useful insights gained from hands-on experience, as well as a theoretical foundation. In this convenient reference you will find information not previously gathered in one source-including comparative developmental milestones, historical data, and a glossary of terms used in developmental toxicity evaluation. This handbook is a practical guide for individuals who are responsible for testing chemical agents and for regulatory scientists who must evaluate studies, interpret data, and perform risk assessments. Packed with features, the Handbook of Developmental Toxicology is ideal for training students and technicians in developmental toxicology.
Author : OECD
Publisher : OECD Publishing
ISBN 13 : 9264070826
Total Pages : 14 pages
Book Rating : 4.2/5 (64 download)
Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 414: Prenatal Developmental Toxicity Study written by OECD and published by OECD Publishing. This book was released on 2018-06-27 with total page 14 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline for developmental toxicity testing is designed to provide general information concerning the effects of prenatal exposure on the pregnant test animal and on the developing organism. The test substance is normally administered to ...
Author : William Slikker, Jr.
Publisher : Academic Press
ISBN 13 : 0128093943
Total Pages : 616 pages
Book Rating : 4.1/5 (28 download)
Download or read book Handbook of Developmental Neurotoxicology written by William Slikker, Jr. and published by Academic Press. This book was released on 2018-01-04 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Developmental Neurotoxicology, Second Edition, provides a comprehensive view of the fundamental aspects of neurodevelopment, the pathways and agents that affect them, relevant clinical syndromes, and risk assessment procedures for developmental neurotoxicants. The editors and chapter authors are internationally recognized experts whose collaboration heralds a remarkable advance in the field, bridging developmental neuroscience with the principles of neurotoxicology. The book features eight new chapters with newly recruited authors, making it an essential text for students and professionals in toxicology, neurotoxicology, developmental biology, pharmacology, and neuroscience. Presents a comprehensive, up-to-date resource on developmental neurotoxicology with updated chapters from the first edition Contains new chapters that focus on subjects recent to the field Includes well-illustrated material, with diagrams, charts, and tables Contains compelling case studies and chapters written by world experts
Author : Amy J. Clippinger
Publisher : Frontiers Media SA
ISBN 13 : 2832508596
Total Pages : 139 pages
Book Rating : 4.8/5 (325 download)
Download or read book Chemical Testing Using New Approach Methodologies (NAMs) written by Amy J. Clippinger and published by Frontiers Media SA. This book was released on 2022-12-16 with total page 139 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Chantra Eskes
Publisher : Springer
ISBN 13 : 3319338269
Total Pages : 407 pages
Book Rating : 4.3/5 (193 download)
Download or read book Validation of Alternative Methods for Toxicity Testing written by Chantra Eskes and published by Springer. This book was released on 2016-09-26 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides information on best practices and new thinking regarding the validation of alternative methods for toxicity testing. It covers the validation of experimental and computational methods and integrated approaches to testing and assessment. Validation strategies are discussed for methods employing the latest technologies such as tissue-on-a-chip systems, stem cells and transcriptomics, and for methods derived from pathway-based concepts in toxicology. Validation of Alternative Methods for Toxicity Testing is divided into two sections, in the first, practical insights are given on the state-of-the-art and on approaches that have resulted in successfully validated and accepted alternative methods. The second section focuses on the evolution of validation principles and practice that are necessary to ensure fit-for-purpose validation that has the greatest impact on international regulatory acceptance of alternative methods. In this context validation needs to keep pace with the considerable scientific advancements being made in toxicology, the availability of sophisticated tools and techniques that can be applied in a variety of ways, and the increasing societal and regulatory demands for better safety assessment. This book will be a useful resource for scientists in the field of toxicology, both from industry and academia, developing new test methods, strategies or techniques, as well as Governmental and regulatory authorities interested in understanding the principles and practicalities of validation of alternative methods for toxicity testing.
