Temporal Aspects In The Testing Of Chemicals For Endocrine Disrupting Effects In Relation To Human Health And The Environment

Download Temporal Aspects In The Testing Of Chemicals For Endocrine Disrupting Effects In Relation To Human Health And The Environment full books in PDF, epub, and Kindle. Read online Temporal Aspects In The Testing Of Chemicals For Endocrine Disrupting Effects In Relation To Human Health And The Environment ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!

Hormonally Active Agents in the Environment

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309064198
Total Pages : 453 pages
Book Rating : 4.3/5 (9 download)

DOWNLOAD NOW!

Book Synopsis Hormonally Active Agents in the Environment by : National Research Council

Download or read book Hormonally Active Agents in the Environment written by National Research Council and published by National Academies Press. This book was released on 2000-02-03 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: Some investigators have hypothesized that estrogens and other hormonally active agents found in the environment might be involved in breast cancer increases and sperm count declines in humans as well as deformities and reproductive problems seen in wildlife. This book looks in detail at the science behind the ominous prospect of "estrogen mimics" threatening health and well-being, from the level of ecosystems and populations to individual people and animals. The committee identifies research needs and offers specific recommendations to decision-makers. This authoritative volume: Critically evaluates the literature on hormonally active agents in the environment and identifies known and suspected toxicologic mechanisms and effects of fish, wildlife, and humans. Examines whether and how exposure to hormonally active agents occursâ€"in diet, in pharmaceuticals, from industrial releases into the environmentâ€"and why the debate centers on estrogens. Identifies significant uncertainties, limitations of knowledge, and weaknesses in the scientific literature. The book presents a wealth of information and investigates a wide range of examples across the spectrum of life that might be related to these agents.

Endocrine Disruption and Human Health

Author : Philippa D. Darbre
Publisher : Academic Press
ISBN 13 : 0128011203
Total Pages : 390 pages
Book Rating : 4.1/5 (28 download)

DOWNLOAD NOW!

Book Synopsis Endocrine Disruption and Human Health by : Philippa D. Darbre

Download or read book Endocrine Disruption and Human Health written by Philippa D. Darbre and published by Academic Press. This book was released on 2015-03-21 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: Endocrine Disruption and Human Health starts with an overview of what endocrine disruptors are, the issues surrounding them, and the source of these chemicals in the ecosystem. This is followed by an overview of the mechanisms of action and assay systems. The third section includes chapters written by specialists on different aspects of concern for the effects of endocrine disruption on human health. Finally, the authors consider the risk assessment of endocrine disruptors and the pertinent regulation developed by the EU, the US FDA, as well as REACH and NGOs. The book has been written for researchers and research clinicians interested in learning about the actions of endocrine disruptors and current evidence justifying concerns for human health but is useful for those approaching the subject for the first time, graduate students, and advanced undergraduate students. - Provides readers with access to a range of information from the basic mechanisms and assays to cutting-edge research investigating concerns for human health - Presents a comprehensive, translational look at all aspects of endocrine disruption and its effects on human health - Offers guidance on the risk assessment of endocrine disruptors and current relevant regulatory considerations

Physiology of the Cladocera

Author : Nikolai N. Smirnov
Publisher : Academic Press
ISBN 13 : 0128052813
Total Pages : 420 pages
Book Rating : 4.1/5 (28 download)

DOWNLOAD NOW!

Book Synopsis Physiology of the Cladocera by : Nikolai N. Smirnov

Download or read book Physiology of the Cladocera written by Nikolai N. Smirnov and published by Academic Press. This book was released on 2017-06-01 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Physiology of the Cladocera, Second Edition, is a much-needed summary of foundational information on these increasingly important model organisms. This unique and valuable review is based on the world's literature, including Russian research not previously widely available, and offers systematically arranged data on the physiology of Cladocera, assisting with explanation of their life and distribution. It features the addition of new sections and a vast amount of new information, such as the latest data on feeding, nutrition, pathological physiology, chemical composition, neurosecretion, and behavior, as well as hormonal regulation, antioxidants, and the biochemical background of effects of natural and anthropogenic factors. Additional expertly updated contributions in genetics and cytology, and a new chapter in embryology, round out the physiological chapters, and provide comprehensive insight into the state of knowledge of Cladocera and their underlying mechanisms. Cladocera crustaceans have become globally studied for many purposes, including genetic, molecular, ecological, environmental, water quality, systematics, and evolutionary biology research. Since the genome of Daphnia was sequenced and published, that system has gained much wider exposure, also leading to a rapidly growing awareness of the importance of understanding physiological processes as they relate to evolutionary and ecological genomics as well as ecogenomic toxicology. However, the physiological background on Cladocera has been fragmentary (including on the other 700 known species besides Daphnia), despite the extensive literature on species identification and morphology. This work addresses this issue by collecting and synthesizing from the literature the state of knowledge of cladoceran physiology, including discussion on both adequately and inadequately investigated fields, and thus directions of future research. - Summarizes fundamental information obtained in recent years, including on steroids, antioxidants, hormones, nanoparticles, and impact of wastewater of pharmaceutical industries - Provides the foundational information needed for scientists and practitioners from a variety of fields, including conservation and evolutionary biology, genomics, ecology, ecotoxicology, comparative physiology, limnology, zoology–carcinology, and water quality assessment - Features coverage of both Daphniids and representatives of other families, with attention drawn to little-studied aspects of their physiology, especially of those living in the litt oral zone - Includes guidance to the literature on cladoceran physiology in four languages - Discusses advantages and shortcomings of Cladocera as experimental animals and indicators of water quality

Application of Systematic Review Methods in an Overall Strategy for Evaluating Low-Dose Toxicity from Endocrine Active Chemicals

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309458625
Total Pages : 423 pages
Book Rating : 4.3/5 (94 download)

DOWNLOAD NOW!

Book Synopsis Application of Systematic Review Methods in an Overall Strategy for Evaluating Low-Dose Toxicity from Endocrine Active Chemicals by : National Academies of Sciences, Engineering, and Medicine

Download or read book Application of Systematic Review Methods in an Overall Strategy for Evaluating Low-Dose Toxicity from Endocrine Active Chemicals written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-08-14 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: To safeguard public health, the US Environmental Protection Agency (EPA) must keep abreast of new scientific information and emerging technologies so that it can apply them to regulatory decision-making. For decades the agency has dealt with questions about what animal-testing data to use to make predictions about human health hazards, how to perform dose-response extrapolations, how to identify and protect susceptible subpopulations, and how to address uncertainties. As alternatives to traditional toxicity testing have emerged, the agency has been faced with additional questions about how to incorporate data from such tests into its chemical assessments and whether such tests can replace some traditional testing methods. Endocrine active chemicals (EACs) have raised concerns that traditional toxicity-testing protocols might be inadequate to identify all potential hazards to human health because they have the ability to modulate normal hormone function, and small alterations in hormone concentrations, particularly during sensitive life stages, can have lasting and significant effects. To address concerns about potential human health effects from EACs at low doses, this report develops a strategy to evaluate the evidence for such low-dose effects.

Toxicological Profile for Lead

Author :
Publisher :
ISBN 13 :
Total Pages : 584 pages
Book Rating : 4.3/5 (91 download)

DOWNLOAD NOW!

Book Synopsis Toxicological Profile for Lead by :

Download or read book Toxicological Profile for Lead written by and published by . This book was released on 2007 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Waste Incineration and Public Health

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 030906371X
Total Pages : 336 pages
Book Rating : 4.3/5 (9 download)

DOWNLOAD NOW!

Book Synopsis Waste Incineration and Public Health by : National Research Council

Download or read book Waste Incineration and Public Health written by National Research Council and published by National Academies Press. This book was released on 2000-10-21 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Incineration has been used widely for waste disposal, including household, hazardous, and medical wasteâ€"but there is increasing public concern over the benefits of combusting the waste versus the health risk from pollutants emitted during combustion. Waste Incineration and Public Health informs the emerging debate with the most up-to-date information available on incineration, pollution, and human healthâ€"along with expert conclusions and recommendations for further research and improvement of such areas as risk communication. The committee provides details on: Processes involved in incineration and how contaminants are released. Environmental dynamics of contaminants and routes of human exposure. Tools and approaches for assessing possible human health effects. Scientific concerns pertinent to future regulatory actions. The book also examines some of the social, psychological, and economic factors that affect the communities where incineration takes place and addresses the problem of uncertainty and variation in predicting the health effects of incineration processes.

Endocrine-Disrupting Chemicals

Author : Andrea C. Gore
Publisher : Springer Science & Business Media
ISBN 13 : 159745107X
Total Pages : 361 pages
Book Rating : 4.5/5 (974 download)

DOWNLOAD NOW!

Book Synopsis Endocrine-Disrupting Chemicals by : Andrea C. Gore

Download or read book Endocrine-Disrupting Chemicals written by Andrea C. Gore and published by Springer Science & Business Media. This book was released on 2007-06-08 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides comprehensive coverage of the three most important themes in the field of Endocrine Disrupting Chemicals (EDC) research: the basic biology of EDCs, particularly their effects on reproductive systems; EDC effects on humans and wildlife, including biomedical considerations; and potential interventions and practical advice for dealing with the problem of EDCs.

Environmental Epigenetics

Author : L. Joseph Su
Publisher : Springer
ISBN 13 : 1447166787
Total Pages : 327 pages
Book Rating : 4.4/5 (471 download)

DOWNLOAD NOW!

Book Synopsis Environmental Epigenetics by : L. Joseph Su

Download or read book Environmental Epigenetics written by L. Joseph Su and published by Springer. This book was released on 2015-05-18 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines the toxicological and health implications of environmental epigenetics and provides knowledge through an interdisciplinary approach. Included in this volume are chapters outlining various environmental risk factors such as phthalates and dietary components, life states such as pregnancy and ageing, hormonal and metabolic considerations and specific disease risks such as cancer cardiovascular diseases and other non-communicable diseases. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses.

Environmental Neurotoxicology

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309045312
Total Pages : 167 pages
Book Rating : 4.3/5 (9 download)

DOWNLOAD NOW!

Book Synopsis Environmental Neurotoxicology by : National Research Council

Download or read book Environmental Neurotoxicology written by National Research Council and published by National Academies Press. This book was released on 1992-02-01 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientists agree that exposure to toxic agents in the environment can cause neurological and psychiatric illnesses ranging from headaches and depression to syndromes resembling parkinsonism. It can even result in death at high exposure levels. The emergence of subclinical neurotoxicity-the concept that long-term impairments can escape clinical detection-makes the need for risk assessment even more critical. This volume paves the way toward definitive solutions, presenting the current consensus on risk assessment and environmental toxicants and offering specific recommendations. The book covers: The biologic basis of neurotoxicity. Progress in the application of biologic markers. Reviews of a wide range of in vitro and in vivo testing techniques. The use of surveillance and epidemiology to identify neurotoxic hazards that escape premarket screening. Research needs. This volume will be an important resource for policymakers, health specialists, researchers, and students.

Marine Anthropogenic Litter

Author : Melanie Bergmann
Publisher : Springer
ISBN 13 : 3319165100
Total Pages : 456 pages
Book Rating : 4.3/5 (191 download)

DOWNLOAD NOW!

Book Synopsis Marine Anthropogenic Litter by : Melanie Bergmann

Download or read book Marine Anthropogenic Litter written by Melanie Bergmann and published by Springer. This book was released on 2015-06-01 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes how man-made litter, primarily plastic, has spread into the remotest parts of the oceans and covers all aspects of this pollution problem from the impacts on wildlife and human health to socio-economic and political issues. Marine litter is a prime threat to marine wildlife, habitats and food webs worldwide. The book illustrates how advanced technologies from deep-sea research, microbiology and mathematic modelling as well as classic beach litter counts by volunteers contributed to the broad awareness of marine litter as a problem of global significance. The authors summarise more than five decades of marine litter research, which receives growing attention after the recent discovery of great oceanic garbage patches and the ubiquity of microscopic plastic particles in marine organisms and habitats. In 16 chapters, authors from all over the world have created a universal view on the diverse field of marine litter pollution, the biological impacts, dedicated research activities, and the various national and international legislative efforts to combat this environmental problem. They recommend future research directions necessary for a comprehensive understanding of this environmental issue and the development of efficient management strategies. This book addresses scientists, and it provides a solid knowledge base for policy makers, NGOs, and the broader public.

Polychlorinated Biphenyls

Author : Obaid Faroon
Publisher : WHO
ISBN 13 :
Total Pages : 68 pages
Book Rating : 4.3/5 (243 download)

DOWNLOAD NOW!

Book Synopsis Polychlorinated Biphenyls by : Obaid Faroon

Download or read book Polychlorinated Biphenyls written by Obaid Faroon and published by WHO. This book was released on 2003 with total page 68 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polychlorinated Biphenyls (PCBs) are synthetic chlorinated hydrocarbon compounds, produced commercially since 1929 for use in a variety of products including plastics and adhesives, surface coatings, inks, flame retardants, pesticides and paints. PCBs are environmentally persistent, and accumulate in the food chain. They are designated by the Stockholm Convention on Persistent Organic Pollutants as persistent pollutants, and many countries have severely restricted or banned the production of PCBs. This report evaluates the effects of PCBs on human health, caused due to exposure by inhaling contaminated air or ingesting contaminated food and water.

Water Quality for Ecosystem and Human Health

Author : Geneviève M. Carr
Publisher : UNEP/Earthprint
ISBN 13 : 9789295039513
Total Pages : 132 pages
Book Rating : 4.0/5 (395 download)

DOWNLOAD NOW!

Book Synopsis Water Quality for Ecosystem and Human Health by : Geneviève M. Carr

Download or read book Water Quality for Ecosystem and Human Health written by Geneviève M. Carr and published by UNEP/Earthprint. This book was released on 2008 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt: This document is intended to provide an overview of the major components of surface and ground water quality and how these relate to ecosystem and human health. Local, regional and global assessments of water quality monitoring data are used to illustrate key features of aquatic environments, and to demonstrate how human activities on the landscape can influence water quality in both positive and negative ways. Clear and concise background knowledge on water quality can serve to support other water assessments.

Toxicological Profile for Toluene

Author :
Publisher :
ISBN 13 :
Total Pages : 366 pages
Book Rating : 4.:/5 (318 download)

DOWNLOAD NOW!

Book Synopsis Toxicological Profile for Toluene by :

Download or read book Toxicological Profile for Toluene written by and published by . This book was released on 2000 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Contemporary Endocrinology

Author : Sidney H. Ingbar
Publisher : Springer Science & Business Media
ISBN 13 : 1475748574
Total Pages : 409 pages
Book Rating : 4.4/5 (757 download)

DOWNLOAD NOW!

Book Synopsis Contemporary Endocrinology by : Sidney H. Ingbar

Download or read book Contemporary Endocrinology written by Sidney H. Ingbar and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt: Those who are familiar with the two volumes of The Year in Endocrinology may, at first glance, fail to recognize their relationship to the present volume, Contemporary Endocrinology. The name is different and the cover design different, but nonetheless the admonition against judging a book by its cover is very well taken in this instance. In fact, Contemporary Endocrinology is not only the direct linear descendant of The Year in Endocrinology, it is a purposeful clone thereof-the topics are unchanged, the talented group of authors is unchanged, and most importantly, both the objective of the work and the manner in which that objective is approached are unchanged. The objective is, of course, to assist the reader in maintaining currency with respect to important developments, both basic and clinical, in the major areas of endocrinology. We are all much too familiar, unfortunately, with the difficulty of maintaining currency these days. Our approach to dealing with the informational inflation that we are suffering is similar to that used by economists in dealing with monetary inflation, that is, to increase interest. This we have attempted to do by providing for the reader an easy-to-read group of essays in which advances in individual areas of endocrinology are re viewed broadly, synthesized, and placed into perspective by a group of authors who are authorities in their individual fields. They serve, not as guest artists, but as members of a stable Editorial Board that provides continuity by contributing to successive volumes.

Toxicological Profile for Chlordane

Author :
Publisher :
ISBN 13 :
Total Pages : 286 pages
Book Rating : 4.:/5 (321 download)

DOWNLOAD NOW!

Book Synopsis Toxicological Profile for Chlordane by :

Download or read book Toxicological Profile for Chlordane written by and published by . This book was released on 1994 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Progress Toward Transforming the Integrated Risk Information System (IRIS) Program

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309474949
Total Pages : 130 pages
Book Rating : 4.3/5 (94 download)

DOWNLOAD NOW!

Book Synopsis Progress Toward Transforming the Integrated Risk Information System (IRIS) Program by : National Academies of Sciences, Engineering, and Medicine

Download or read book Progress Toward Transforming the Integrated Risk Information System (IRIS) Program written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2018-04-11 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past several years, the US Environmental Protection Agency (EPA) has been transforming the procedures of its Integrated Risk Information System (IRIS), a program that produces hazard and doseâ€'response assessments of environmental chemicals and derives toxicity values that can be used to estimate risks posed by exposures to them. The transformation was initiated after suggestions for program reforms were provided in a 2011 report from the National Academies of Sciences, Engineering, and Medicine that reviewed a draft IRIS assessment of formaldehyde. In 2014, the National Academies released a report that reviewed the IRIS program and evaluated the changes implemented in it since the 2011 report. Since 2014, new leadership of EPA's National Center for Environmental Assessment (NCEA) and IRIS program has instituted even more substantive changes in the IRIS program in response to the recommendations in the 2014 report. Progress Toward Transforming the Integrated Risk Information System Program: A 2018 Evaluation reviews the EPA's progress toward addressing the past recommendations from the National Academies.

Green Toxicology

Author : Alexandra Maertens
Publisher : Royal Society of Chemistry
ISBN 13 : 1839164409
Total Pages : 225 pages
Book Rating : 4.8/5 (391 download)

DOWNLOAD NOW!

Book Synopsis Green Toxicology by : Alexandra Maertens

Download or read book Green Toxicology written by Alexandra Maertens and published by Royal Society of Chemistry. This book was released on 2022-02-01 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: Green toxicology is an integral part of green chemistry. One of the key goals of green chemistry is to design less toxic chemicals. Therefore, an understanding of toxicology and hazard assessment is important for any chemist working in green chemistry, but toxicology is rarely part of most chemists' education. As a consequence, chemists lack the toxicological lens necessary to view chemicals in order to design safer substitutions. This book seeks to fill that gap and demonstrate how a basic understanding of toxicology, as well as the tools of in silico and in vitro toxicology, can be an integral part of green chemistry. R&D chemists, product stewards, and toxicologists who work in the field of sustainability, can all benefit from integrating green toxicology principles into their work. Topics include in silico tools for hazard assessment, toxicity testing, and lifecycle considerations, this book aims to act as a bridge between green toxicologists and green chemists.