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Technical Report On Toxicology And Carcinogenesis Studies Of Bromochloroacetic Acid Cas No 5589 96 8 In F344 N Rats And B6c3f1 Mice Drinking Water Studies
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Book Synopsis Technical Report on Toxicology and Carcinogenesis Studies of Bromochloroacetic Acid (CAS No. 5589-96-8) in F344/N Rats and B6C3F1 Mice (Drinking Water Studies) by : R. L. Melnick
Download or read book Technical Report on Toxicology and Carcinogenesis Studies of Bromochloroacetic Acid (CAS No. 5589-96-8) in F344/N Rats and B6C3F1 Mice (Drinking Water Studies) written by R. L. Melnick and published by DIANE Publishing. This book was released on 2009-09 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bromochloroacetic acid is a water disinfection by-product. Bromochloroacetic acid was nominated for toxicity and carcinogenicity studies in rats and mice because of widespread human exposure and because a related dihaloacetate, dichloroacetate, was found to be carcinogenic to the liver of rats and mice. Drinking water was selected as the route of exposure to mimic human exposure to this chemical. Male and female F344/N rats and B6C3F1 mice were exposed to bromochloroacetic acid (greater than 95% pure) in drinking water for 2 weeks, 3 months, or 2 years. Genetic toxicology studies were conducted in ¿Salmonella typhimurium,¿ ¿Escherichia coli,¿ and peripheral blood erythrocytes of exposed mice. Illustrations.
Book Synopsis NTP Technical Report on the Toxicology and Carcinogenesis Studies of Bromochloroacetic Acid (CAS No. 5589-96-8) in F344/N Rats and B6C3F1 Mice by : Ronald L. Melnick
Download or read book NTP Technical Report on the Toxicology and Carcinogenesis Studies of Bromochloroacetic Acid (CAS No. 5589-96-8) in F344/N Rats and B6C3F1 Mice written by Ronald L. Melnick and published by . This book was released on 2009 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Ministère de la guerre. 4e direction. Administration. Bureau des hôpitaux et des invalides. Programme d'un concours pour l'admission aux emplois de médecin stagiaire à l'école impériale d'application de médecine et de pharmacie militaire de Paris by :
Download or read book Ministère de la guerre. 4e direction. Administration. Bureau des hôpitaux et des invalides. Programme d'un concours pour l'admission aux emplois de médecin stagiaire à l'école impériale d'application de médecine et de pharmacie militaire de Paris written by and published by . This book was released on 1856 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Environmental Toxicants by : Morton Lippmann
Download or read book Environmental Toxicants written by Morton Lippmann and published by John Wiley & Sons. This book was released on 2009-03-26 with total page 1189 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides the most current information and research available for performing risk assessments on exposed individuals and populations, giving guidance to public health authorities, primary care physicians, and industrial managers Reviews current knowledge on human exposure to selected chemical agents and physical factors in the ambient environment Updates and revises the previous edition, in light of current scientific literature and its significance to public health concerns Includes new chapters on: airline cabin exposures, arsenic, endocrine disruptors, and nanoparticles
Book Synopsis Disinfection By-Products and Human Health by : Steve E. Hrudey
Download or read book Disinfection By-Products and Human Health written by Steve E. Hrudey and published by IWA Publishing. This book was released on 2012-04-30 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: Disinfection By-Products and Human Health is based on contributions from speakers who participated in May 2011 workshops on Disinfection By-Products (DBPs) and Human Health at Ozwater 11 in Adelaide, Australia or at an AWA sponsored workshop at the Curtin Water Quality Research Centre, Perth, Australia. The contributions are prepared to facilitate communication with practitioners, rather than researchers, making use of overview illustrations rather than dense text or data tables. Each chapter concludes with up to 5 key findings that are take-home messages for practitioners. Disinfection By-Products and Human Health is aimed specifically at drinking water professionals (engineers, chemists and public health professionals) working on the front lines of drinking water issues where they must encounter actual day-to-day issues of risk management concerning DBPs in relation to all the other regulatory and water quality issues they must manage. Although a topic this complex is certainly not amenable to simplistic explanations, this book aims to provide drinking water professionals with a pragmatic assessment of the current evidence and emerging issues concerning DBPs and public health. Disinfection By-Products and Human Health is an essential, practical and accessible guide for drinking water professionals, engineers, chemists and public health professionals. Editors: Steve E. Hrudey, Professor Emeritus, Analytical & Environmental Toxicology, University of Alberta, Canada, Jeffrey W.A. Charrois, Director and Associate Professor, Curtin Water Quality Research Centre, Curtin University of Technology, Australia, Steve Hrudey is professor emeritus in analytical and environmental toxicology in the University of Alberta's Faculty of Medicine & Dentistry. He spent 13 years as a cabinet-appointed member of the Alberta Environmental Appeals Board, the last four as chair, and was the first non-lawyer to hold this position. During this period, he served on 36 public hearing panels, 19 as chair of the panel. In addition he has testified before senate committees in Canada and the Legislative Council in Western Australia. Hrudey has served on a number of high-profile expert panels, including the Research Advisory Panel to the Walkerton Inquiry (2000-2002), the Expert Panel on Safe Drinking Water for First Nations (2006), the Technical Advisory Committee to the B.C. Minister of Health on turbidity and microbial risk in drinking water (2007-2008, as chair), the Expert Advisory Panel on Water Quality for Washington, D.C., to the U.S. Army Corps of Engineers (2009-2011) and chair of the Royal Society of Canada Expert Panel on Environmental and Health Impacts of Canada's Oil Sands Industry (2009-2010). He has also co-authored or edited nine books, including the widely acclaimed book inspired by the Walkerton tragedy: Safe Drinking Water - Lessons from Recent Outbreaks in Affluent Nations (IWA Publishing, 2004). He has written 26 book chapters, 19 expert panel reports, 163 refereed journal articles, 15 science discussions, six media op-eds and 73 conference proceeding papers. Hrudey is the 2012 winner of the American Water Works Association A.P. Black Research Award for contributions to water science and water supply. This book is sponsored by Australian Water Association (AWA)
Book Synopsis NTP Technical Report on the Toxicology Studies of Bromodichloroacetic Acid (CASRN 71133-14-7) in F344/N Rats and B6C3F1/N Mice and Toxicology and Carcinogenesis Studies of Bromodichloroacetic Acid in F344/NTac Rats and B6C3F1/N Mice (Drinking Water Studies) by :
Download or read book NTP Technical Report on the Toxicology Studies of Bromodichloroacetic Acid (CASRN 71133-14-7) in F344/N Rats and B6C3F1/N Mice and Toxicology and Carcinogenesis Studies of Bromodichloroacetic Acid in F344/NTac Rats and B6C3F1/N Mice (Drinking Water Studies) written by and published by . This book was released on 2015 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: TWO-WEEK STUDY IN F344/N RATS: Groups of five male and five female rats were exposed to 0, 62.5, 125, 250, 500, or 1,000\smg bromodichloroacetic acid/L drinking water for 16\sdays (equivalent to average daily doses of approximately 7, 15, 31, 56, or 131\smg bromodichloroacetic acid/kg body weight to males and 8, 15, 30, 58, or 113\smg/kg to females). All rats survived to the end of the study. Mean body weights of exposed groups of male and female rats were similar to those of the controls. Water consumption by exposed and control groups was similar. No organ weight differences were attributed to exposure to bromodichloroacetic acid. No gross or histologic lesions related to bromodichloroacetic acid exposure were observed. CONCLUSIONS: Under the conditions of these 2-year studies, there was clear evidence of carcinogenic activity (see Explanation of Levels of Evidence of Carcinogenic Activity; see summary of the peer review panel comments and the public discussion on this Technical Report in Appendix P) of bromodichloroacetic acid in male F344/NTac rats based on increased incidences of malignant mesothelioma and the combined incidences of epithelial tumors of the skin. Occurrences of subcutaneous fibromas were also related to exposure to bromodichloroacetic acid. Occurrences of glioma or oligodendroglioma (combined) of the brain, squamous cell papilloma and squamous cell carcinoma of the oral cavity (oral mucosa or tongue), adenoma of the large intestine, and fibroadenoma of the mammary gland may have been related to exposure to bromodichloroacetic acid. There was clear evidence of carcinogenic activity of bromodichloroacetic acid in female F344/NTac rats based on increased incidences of fibroadenoma and carcinoma of the mammary gland. The occurrences of glioma or oligodendroglioma (combined) of the brain may have been related to bromodichloroacetic acid exposure. There was clear evidence of carcinogenic activity of bromodichloroacetic acid in male B6C3F1/N mice based on increased incidences of hepatocellular carcinoma and hepatoblastoma and increased incidences of adenoma or carcinoma (combined) of the Harderian gland. There was clear evidence of carcinogenic activity of bromodichloroacetic acid in female B6C3F1/N mice based on increased incidences of hepatocellular adenoma, hepatocellular carcinoma, and hepatoblastoma. Exposure to bromodichloroacetic acid for 2\syears resulted in increased incidences of nonneoplastic lesions in the bone marrow and liver of male and female rats, spleen of female rats, liver of male and female mice, and testis and epididymis of male mice. Synonyms: 2-Bromo-2,2-dichloroacetic acid; bromodichloroethanoic acid.
Book Synopsis NTP Technical Report on the Toxicology and Carcinogenesis Studies of Bromodichloromethane (CAS No. 75-27-4) in Male F344/N Rats and Female B6C3F1 Mice by : National Toxicology Program (U.S.)
Download or read book NTP Technical Report on the Toxicology and Carcinogenesis Studies of Bromodichloromethane (CAS No. 75-27-4) in Male F344/N Rats and Female B6C3F1 Mice written by National Toxicology Program (U.S.) and published by . This book was released on 2006 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis NTP Technical Report on the Toxicology and Carcinogenesis Studies of 2,3-dibromo-1-propanol (CAS No. 96-13-9) in F344/N Rats and B6C3F1 Mice (dermal Studies) by :
Download or read book NTP Technical Report on the Toxicology and Carcinogenesis Studies of 2,3-dibromo-1-propanol (CAS No. 96-13-9) in F344/N Rats and B6C3F1 Mice (dermal Studies) written by and published by . This book was released on 1993 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis NTP Technical Report on the Toxicology and Carcinogenesis Studies of 1-chloro-2-propanol (technical Grade) (CAS No. 127-00-4) in F344/N Rats and B6C3F1 Mice (drinking Water Studies) by :
Download or read book NTP Technical Report on the Toxicology and Carcinogenesis Studies of 1-chloro-2-propanol (technical Grade) (CAS No. 127-00-4) in F344/N Rats and B6C3F1 Mice (drinking Water Studies) written by and published by . This book was released on 1998 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis NTP Technical Report on the Toxicology and Carcinogenesis Studies of Isobutyl Nitrite (CAS No. 542-56-3) in F344/N Rats and B6C3F1 Mice (inhalation Studies). by :
Download or read book NTP Technical Report on the Toxicology and Carcinogenesis Studies of Isobutyl Nitrite (CAS No. 542-56-3) in F344/N Rats and B6C3F1 Mice (inhalation Studies). written by and published by . This book was released on 1996 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis NTP Technical Report on the Toxicology and Carcinogenesis Studies of Tris(2-chloroethyl) Phosphate (CAS No. 115-96-8) in F344/N Rats and B6C3F1 Mice (gavage Studies) by :
Download or read book NTP Technical Report on the Toxicology and Carcinogenesis Studies of Tris(2-chloroethyl) Phosphate (CAS No. 115-96-8) in F344/N Rats and B6C3F1 Mice (gavage Studies) written by and published by . This book was released on 1990 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Technical Report Series written by and published by . This book was released on 2009 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :National Toxicology Program NTP : US Department of Health and Human Services : Public Health Service : National Institutes of Health Publisher : ISBN 13 : Total Pages : pages Book Rating :4.:/5 (114 download)
Book Synopsis Toxicology and carcinogenesis studies of 1-chloro-2-propanol in F344-N rats and B6C3F1 mice (drinking water studies). by : National Toxicology Program NTP : US Department of Health and Human Services : Public Health Service : National Institutes of Health
Download or read book Toxicology and carcinogenesis studies of 1-chloro-2-propanol in F344-N rats and B6C3F1 mice (drinking water studies). written by National Toxicology Program NTP : US Department of Health and Human Services : Public Health Service : National Institutes of Health and published by . This book was released on 1997 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis NTP Technical Report on the Toxicology and Carcinogenesis Studies of Bromoethane (ethyl Bromide) (CAS No. 74-96-4) in F344/N Rats and B6C3F1 Mice (inhalation Studies) by : Joseph Roycroft
Download or read book NTP Technical Report on the Toxicology and Carcinogenesis Studies of Bromoethane (ethyl Bromide) (CAS No. 74-96-4) in F344/N Rats and B6C3F1 Mice (inhalation Studies) written by Joseph Roycroft and published by . This book was released on 1989 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :American Water Works Association Publisher :McGraw Hill Professional ISBN 13 :0071630104 Total Pages :1696 pages Book Rating :4.0/5 (716 download)
Book Synopsis Water Quality & Treatment: A Handbook on Drinking Water by : American Water Works Association
Download or read book Water Quality & Treatment: A Handbook on Drinking Water written by American Water Works Association and published by McGraw Hill Professional. This book was released on 2010-12-06 with total page 1696 pages. Available in PDF, EPUB and Kindle. Book excerpt: The definitive water quality and treatment resource--fully revised and updated Comprehensive, current, and written by leading experts, Water Quality & Treatment: A Handbook on Drinking Water, Sixth Edition covers state-of-the-art technologies and methods for water treatment and quality control. Significant revisions and new material in this edition reflect the latest advances and critical topics in water supply and treatment. Presented by the American Water Works Association, this is the leading source of authoritative information on drinking water quality and treatment. NEW CHAPTERS ON: Chemical principles, source water composition, and watershed protection Natural treatment systems Water reuse for drinking water augmentation Ultraviolet light processes Formation and control of disinfection by-products DETAILED COVERAGE OF: Drinking water standards, regulations, goals, and health effects Hydraulic characteristics of water treatment reactors Gas-liquid processes and chemical oxidation Coagulation, flocculation, sedimentation, and flotation Granular media and membrane filtration Ion exchange and adsorption of inorganic contaminants Precipitation, coprecipitation, and precipitative softening Adsorption of organic compounds by activated carbon Chemical disinfection Internal corrosion and deposition control Microbiological quality control in distribution systems Water treatment plant residuals management
Book Synopsis NTP Technical Report on the Toxicology and Carcinogenesis Studies of Chlorendic Acid (CAS No. 115-28-6) in F344/N Rats and B6C3F1 Mice (feed Studies) by :
Download or read book NTP Technical Report on the Toxicology and Carcinogenesis Studies of Chlorendic Acid (CAS No. 115-28-6) in F344/N Rats and B6C3F1 Mice (feed Studies) written by and published by . This book was released on 1987 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis NTP technical report on the toxicology and carcinogenesis studies of phenolphthalein (CAS no. 77-09-8) in F344/N rats and B6C3F1 mice (feed studies) by :
Download or read book NTP technical report on the toxicology and carcinogenesis studies of phenolphthalein (CAS no. 77-09-8) in F344/N rats and B6C3F1 mice (feed studies) written by and published by . This book was released on 1996 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt:
