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Targeting Thyroid Cancer Microenvironment And Epigenetic Signalling
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Book Synopsis Targeting Thyroid Cancer Microenvironment and Epigenetic Signalling: New Frontiers in Cancer Endocrinology Basic and Clinical Research, 2nd Edition by : Carmelo Nucera
Download or read book Targeting Thyroid Cancer Microenvironment and Epigenetic Signalling: New Frontiers in Cancer Endocrinology Basic and Clinical Research, 2nd Edition written by Carmelo Nucera and published by Frontiers Media SA. This book was released on with total page 133 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Targeting Thyroid Cancer Microenvironment and Epigenetic Signalling by :
Download or read book Targeting Thyroid Cancer Microenvironment and Epigenetic Signalling written by and published by . This book was released on 2014 with total page 131 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Molecular Basis of Thyroid Cancer by : NADIR R. FARID
Download or read book Molecular Basis of Thyroid Cancer written by NADIR R. FARID and published by Springer Science & Business Media. This book was released on 2006-02-03 with total page 441 pages. Available in PDF, EPUB and Kindle. Book excerpt: - This series is indexed in index Medicus - The turn around time for this series is fast, making the research as accurate as a journal
Book Synopsis Emerging Molecular Signaling Pathways and Therapeutic Targets in the Genitourinary Immune Microenvironment by : Zhangqun Ye
Download or read book Emerging Molecular Signaling Pathways and Therapeutic Targets in the Genitourinary Immune Microenvironment written by Zhangqun Ye and published by Frontiers Media SA. This book was released on 2023-12-29 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is well known that the immune microenvironment is critical to the progression of genitourinary malignancies and benign diseases. A variety of cellular and molecular properties of the immune microenvironment may influence disease outcome by altering the balance of suppressive versus inflammatory or cytotoxic responses. Emerging evidence suggests that immunoediting is a key factor of phenotypic change, immunological alterations caused by physical activity or drug treatments could promote antitumor or anti-inflammatory activity. Conversely, microenvironment deficits or dysregulation can instigate or worsen pathological progression, thereby contributing to urinary disease development and progression. Thus, understanding how immune microenvironments react and maintain appropriate antitumor or anti-inflammatory responses is important for identifying actionable therapies to improve genitourinary health. Recent technological developments, particularly in the areas of genetic modification and redox indicators, provide hopeful new treatments not only in urinary cancer, kidney cancer, bladder cancer, relatively rare adrenocortical cancer, and penile cancer but also in begin diseases like kidney stones and kidney injuries. The purpose of this topic is to provide up-to-date reviews and original articles that highlight research on immunological mediators of tumor progression and inflammatory-related genitourinary diseases, which we hope will not only integrate our current understanding but crystallize nascent questions that will help move the field forward. This research topic aims to inspire novel insights into the immunity mechanisms, novel therapeutic targets, and effective combinational strategies of urinary immunotherapies.
Book Synopsis Tumor Microenvironment: Molecular Mechanisms and Signaling Pathways Involved in Metastatic Progression by : Antonella Zannetti
Download or read book Tumor Microenvironment: Molecular Mechanisms and Signaling Pathways Involved in Metastatic Progression written by Antonella Zannetti and published by Frontiers Media SA. This book was released on 2021-09-30 with total page 566 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Heterogeneity of Cancer Metabolism by : Anne Le
Download or read book The Heterogeneity of Cancer Metabolism written by Anne Le and published by Springer. This book was released on 2018-06-26 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, we delve into the complexity and diversity of cancer metabolism, and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer therapeutic strategies.
Book Synopsis Introduction to Epigenetics by : Renato Paro
Download or read book Introduction to Epigenetics written by Renato Paro and published by Springer Nature. This book was released on 2021-03-23 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access textbook leads the reader from basic concepts of chromatin structure and function and RNA mechanisms to the understanding of epigenetics, imprinting, regeneration and reprogramming. The textbook treats epigenetic phenomena in animals, as well as plants. Written by four internationally known experts and senior lecturers in this field, it provides a valuable tool for Master- and PhD- students who need to comprehend the principles of epigenetics, or wish to gain a deeper knowledge in this field. After reading this book, the student will: Have an understanding of the basic toolbox of epigenetic regulation Know how genetic and epigenetic information layers are interconnected Be able to explain complex epigenetic phenomena by understanding the structures and principles of the underlying molecular mechanisms Understand how misregulated epigenetic mechanisms can lead to disease
Book Synopsis Biotargets of Cancer in Current Clinical Practice by : Mauro Bologna
Download or read book Biotargets of Cancer in Current Clinical Practice written by Mauro Bologna and published by Springer Science & Business Media. This book was released on 2012-04-05 with total page 572 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biotargets of Cancer in Current Clinical Practice presents an updated and reasoned review of the current status of knowledge concerning the major cancer types with a special focus on the current biomarkers, genes involved and the potential future targets of innovative therapies. The volume includes for each major cancer type, a comprehensive although concise discussion of epidemiology, affirmed and innovative biomarkers for diagnosis, and descriptions of the relevant genes for prognosis and (individualized) therapy through biotarget-specific new molecular treatments, with the latest information on the validation status of each novel biomarker. Individual chapters are dedicated to the major cancer types, plus a special chapter on metastasis. The present debate on patentability of genetic information applied to diagnostics and therapeutics of cancer is also discussed.
Book Synopsis Endocrine Pathology by : Fátima Carneiro
Download or read book Endocrine Pathology written by Fátima Carneiro and published by . This book was released on 1995 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Epigenetic therapy against cancer: Toward new molecular targets and technologies by : Christiane Pienna Soares
Download or read book Epigenetic therapy against cancer: Toward new molecular targets and technologies written by Christiane Pienna Soares and published by Frontiers Media SA. This book was released on 2023-06-27 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Signal Transduction in Cancer by : David A. Frank
Download or read book Signal Transduction in Cancer written by David A. Frank and published by Springer Science & Business Media. This book was released on 2002-12-31 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the most exciting areas of cancer research now is the development of agents which can target signal transduction pathways that are activated inappropriately in malignant cells. The understanding of the molecular abnormalities which distinguish malignant cells from their normal counterparts has grown tremendously. This volume summarizes the current research on the role that signal transduction pathways play in the pathogenesis of cancer and how this knowledge may be used to develop the next generation of more effective and less toxic anticancer agents. Series Editor comments: "The biologic behavior of both normal and cancer cells is determined by critical signal transduction pathways. This text provides a comprehensive review of the field. Leading investigators discuss key molecules that may prove to be important diagnostic and/or therapeutic targets."
Book Synopsis MicroRNAs in Cancer by : Cesar Lopez-Camarillo
Download or read book MicroRNAs in Cancer written by Cesar Lopez-Camarillo and published by CRC Press. This book was released on 2013-02-22 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: MicroRNA (miRNA) biology is a cutting-edge topic in basic as well as biomedical research. This is a specialized book focusing on the current understanding of the role of miRNAs in the development, progression, invasion, and metastasis of diverse types of cancer. It also reviews their potential for applications in cancer diagnosis, prognosis, and th
Book Synopsis Tumour microenvironment in cancer research and drug discovery by : Syed Mahmood
Download or read book Tumour microenvironment in cancer research and drug discovery written by Syed Mahmood and published by Frontiers Media SA. This book was released on 2024-05-10 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: The implication of tumour microenvironment (TME) on cancer progression and therapeutic response has profoundly shifted the paradigms of molecular cancer research and drug discovery. The intricate networks of immune-inflammatory cells and signalling, cancer-associated fibroblasts, endothelial cells and adipose cells are extensively researched for diagnostics, therapeutics and predictive values. This includes siRNA and miRNA nanotherapeutics targeting these molecular components, owing to their powerful gene-silencing properties. Despite the concerted effort in the development of drug targeting TME, such as BLZ945 (a colony-stimulating factor-1 receptor inhibitor), there is a void in clinically satisfactory drug to target this intricate factor, thus far.
Book Synopsis Gastric Cancer Phenotype and Treatment by : Annamaria Agnes
Download or read book Gastric Cancer Phenotype and Treatment written by Annamaria Agnes and published by Frontiers Media SA. This book was released on 2022-09-07 with total page 403 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Altered Expression of Proteins in Cancer: Function and Potential Therapeutic Targets by : Varda Shoshan-Barmatz
Download or read book Altered Expression of Proteins in Cancer: Function and Potential Therapeutic Targets written by Varda Shoshan-Barmatz and published by Frontiers Media SA. This book was released on 2022-08-03 with total page 535 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Systems Cancer Biology by : Bor-Sen Chen
Download or read book Systems Cancer Biology written by Bor-Sen Chen and published by Cambridge Scholars Publishing. This book was released on 2021-07-13 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer is a complex and heterogeneous (systematic) disease that exhibits high levels of robustness against various therapeutic interventions. Due to the complex, heterogeneous, and evolving nature of cancer, it is essential for a system-oriented view to be adopted in order to understand the pathogenic mechanism of cancer which will eventually lead to the drug discovery and treatment of patients. This book not only provides new insights from system modeling and large scale experimental data, but also will allow the reader to perceive the systematic characteristics of cancer under some micro-environments. Based on the systems biology method and genome-wide high throughput data, the book presents the PPI network, gene regulatory network and epigenetic network as an integrated genetic and epigenetic cellular network of lung cancer, bladder cancer, thyroid cancer, colorectal cancer, and liver cancer to investigate their core signaling pathways of the carcinogenesis process to identify their corresponding significant carcinogenic biomarkers as drug targets for systems drug discovery and design. Consequently, the book presents the design of a multiple-molecule drug that can target these biomarkers for the therapeutic treatment of cancer with fewer side effects.
Book Synopsis Textbook of Endocrine Surgery by : Orlo H Clark
Download or read book Textbook of Endocrine Surgery written by Orlo H Clark and published by JP Medical Ltd. This book was released on 2016-02-29 with total page 1368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Textbook of Endocrine Surgery, Third Edition, is the latest edition of this highly illustrated, comprehensive guide. Edited by professors from the University of California, San Francisco, this authoritative textbook covers surgical procedures for a broad range of endocrine conditions. Comprised of four sections, divided into 81 chapters, this book examines disorders of the thyroid, parathyroid and adrenal glands, as well as neuroendocrine tumours of the pancreas and gastrointestinal tract. All chapters have been extensively revised and updated, and many new chapters have been added to this edition to reflect recent advances in the field. This book provides up to date information on aetiology, embryology, anatomy, clinical manifestations, diagnostic and localisation procedures, surgical and other treatment modalities for endocrine disorders. Enhanced by 550 full colour images and illustrations, Textbook of Endocrine Surgery is an invaluable resource for surgeons and endocrinologists. Key Points New edition of this richly illustrated, comprehensive guide to endocrine surgery Previous edition published 2005 (9780721601397) Editorial team from the University of California, San Francisco 550 full colour images and illustrations
