Targeted Therapies for Solid Tumors

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Author :
Publisher : Humana Press
ISBN 13 : 1493920472
Total Pages : 270 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Targeted Therapies for Solid Tumors by : Antonio Russo

Download or read book Targeted Therapies for Solid Tumors written by Antonio Russo and published by Humana Press. This book was released on 2015-03-11 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides readers a comprehensive and state-of-the-art overview about the range of applications of targeted therapies for solid tumors. The sections of the book have been structured to review the oncogene addicted tumors, the pharmacology and clinical development of new molecularly targeted agents, the use of biomarkers as prognostic, predictive and surrogate endpoints, and the evaluation of tumor response and specific malignancies treated with targeted agents. The book also covers some of the newest developments in cancer therapy that are not adequately covered by any current available literature. Written by recognized experts in the field, Targeted Therapies for Solid Tumors: A Handbook for Moving Toward New Frontiers in Cancer Treatment provides a unique and valuable resource in the field of molecular oncology, both for those currently in training, and for those already in clinical or research practice.

Targeted Therapies in Oncology

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Author :
Publisher : CRC Press
ISBN 13 : 1842145460
Total Pages : 498 pages
Book Rating : 4.8/5 (421 download)

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Book Synopsis Targeted Therapies in Oncology by : Giuseppe Giaccone

Download or read book Targeted Therapies in Oncology written by Giuseppe Giaccone and published by CRC Press. This book was released on 2013-10-21 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the last edition of this book, major advances have been made in our understanding of key pathways that control tumor progression. This has led to the development of new anticancer agents that have the ability to block the activity of proteins involved in neoplastic cell development and proliferation. Targeted Therapies in Oncology, Second Edi

Handbook of Targeted Cancer Therapy and Immunotherapy

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Author :
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1975179269
Total Pages : 1277 pages
Book Rating : 4.9/5 (751 download)

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Book Synopsis Handbook of Targeted Cancer Therapy and Immunotherapy by : Daniel D. Karp

Download or read book Handbook of Targeted Cancer Therapy and Immunotherapy written by Daniel D. Karp and published by Lippincott Williams & Wilkins. This book was released on 2022-03-28 with total page 1277 pages. Available in PDF, EPUB and Kindle. Book excerpt: Designed for quick, everyday reference, Handbook of Targeted Cancer Therapy and Immunotherapy, 3rd Edition, includes clinical trial results of more than 250 state-of-the-art targeted therapy and immunotherapy agents, providing a practical, intuitive, colorful overview of this rapidly advancing field. Comprehensive yet concise, this easy-access resource by Drs. Daniel D. Karp, Gerald S. Falchook, and JoAnn D. Lim, helps you navigate through the newest research reports and apply the most recent discoveries as they pertain to specific tumor types, actionable molecular targets, and clinical performance of investigational targeted agents and combinations of agents. This handbook presents information distilled by dozens of translational research clinicians and other healthcare experts with hundreds of years of cumulative experience in the revolutionary area of genomically based precision oncology.

Targeted Radionuclide Therapy

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Author :
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1451153260
Total Pages : 564 pages
Book Rating : 4.4/5 (511 download)

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Book Synopsis Targeted Radionuclide Therapy by : Tod W. Speer

Download or read book Targeted Radionuclide Therapy written by Tod W. Speer and published by Lippincott Williams & Wilkins. This book was released on 2012-03-28 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radioimmunotherapy, also known as systemic targeted radiation therapy, uses antibodies, antibody fragments, or compounds as carriers to guide radiation to the targets. It is a topic rapidly increasing in importance and success in treatment of cancer patients. This book represents a comprehensive amalgamation of the radiation physics, chemistry, radiobiology, tumor models, and clinical data for targeted radionuclide therapy. It outlines the current challenges and provides a glimpse at future directions. With significant advances in cell biology and molecular engineering, many targeting constructs are now available that will safely deliver these highly cytotoxic radionuclides in a targeted fashion. A companion website includes the full text and an image bank.

Molecularly Targeted Therapy for Childhood Cancer

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 038769062X
Total Pages : 548 pages
Book Rating : 4.3/5 (876 download)

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Book Synopsis Molecularly Targeted Therapy for Childhood Cancer by : Peter J. Houghton

Download or read book Molecularly Targeted Therapy for Childhood Cancer written by Peter J. Houghton and published by Springer Science & Business Media. This book was released on 2010-09-10 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt: Each chapter will focus on the known molecular characteristics of specific childhood cancers, focusing on how the molecular ‘drivers’ can be exploited from a therapeutic standpoint with currently available targeted agents. Where applicable, integration of targeted therapies with conventional cytotoxic agents will be considered. This volume will provide a comprehensive summary of molecular characteristics of childhood cancers, and how the changes involved in transformation provide us with opportunities for developing relatively less toxic, but curative, therapies.

Treating Cancer with Immunotherapy and Targeted Therapy

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Author :
Publisher : Mercury Learning and Information
ISBN 13 : 1683927524
Total Pages : 235 pages
Book Rating : 4.6/5 (839 download)

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Book Synopsis Treating Cancer with Immunotherapy and Targeted Therapy by : David A. Olle

Download or read book Treating Cancer with Immunotherapy and Targeted Therapy written by David A. Olle and published by Mercury Learning and Information. This book was released on 2022-03-09 with total page 235 pages. Available in PDF, EPUB and Kindle. Book excerpt: Treating cancer has always been a major challenge. Although great strides in treatment have taken place in recent years, all too often current treatments are less than effective, or patients relapse. Newer methods of cancer treatment, namely targeted therapy and immunotherapy have generated great excitement in the scientific community. These newer methods of cancer treatment hold promise for patients who otherwise may have few options. Using the principles of health literacy, this updated edition includes many new therapies and describes the essential features of cancer treatments available to the general public in an engaging and stimulating manner. A simple, question/answer format and the use of illustrations, tables, charts, and boxes that highlight definitions, facts, and website links provide more detailed information. Features: Provides questions and answers about the characteristics of cancer, diagnosis, classifications, surgery, chemotherapy, radiation therapy, targeted therapy, adoptive cell therapy, new developments, and more Cites many new therapies and includes numerous in-text Web links to information at the National Institutes of Health, the National Cancer Institute, journals, and other online sources Uses animations, practical tips, charts and tables, figures, and photos to explain topics under discussion.

Gemcitabine, Pemetrexed, and Targeted Therapies for Solid Tumors

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Author :
Publisher :
ISBN 13 :
Total Pages : 60 pages
Book Rating : 4.:/5 (516 download)

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Book Synopsis Gemcitabine, Pemetrexed, and Targeted Therapies for Solid Tumors by :

Download or read book Gemcitabine, Pemetrexed, and Targeted Therapies for Solid Tumors written by and published by . This book was released on 2002 with total page 60 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Handbook of Targeted Cancer Therapy

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Author :
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1469894580
Total Pages : 310 pages
Book Rating : 4.4/5 (698 download)

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Book Synopsis Handbook of Targeted Cancer Therapy by : Daniel D. Karp

Download or read book Handbook of Targeted Cancer Therapy written by Daniel D. Karp and published by Lippincott Williams & Wilkins. This book was released on 2014-09-09 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: Make optimal use of the latest personalized therapeutic strategies with Handbook of Targeted Cancer Therapy! This concise, practical oncology reference examines more than 140 targeted therapy agents for which clinical trial data are available, and explains when and how you can use them to most effectively combat cancer. Approach clinical challenges from any direction with separate sections on Targets by Organ Site, Carcinogenesis from the Perspective of Targeted Therapy, Molecular Targets and Pathways, and Targeted Therapy Agents. Find information easily thanks to a color-coded format and an intuitive organization. Access the complete contents online and on mobile devices, with regular updates to include newly approved treatments. Important state of the art cancer information for caregivers, researchers, other health care professionals, and even patients

Clinical Trials in Oncology, Third Edition

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Publisher : CRC Press
ISBN 13 : 1439814481
Total Pages : 266 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Clinical Trials in Oncology, Third Edition by : Stephanie Green

Download or read book Clinical Trials in Oncology, Third Edition written by Stephanie Green and published by CRC Press. This book was released on 2012-05-09 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: The third edition of the bestselling Clinical Trials in Oncology provides a concise, nontechnical, and thoroughly up-to-date review of methods and issues related to cancer clinical trials. The authors emphasize the importance of proper study design, analysis, and data management and identify the pitfalls inherent in these processes. In addition, the book has been restructured to have separate chapters and expanded discussions on general clinical trials issues, and issues specific to Phases I, II, and III. New sections cover innovations in Phase I designs, randomized Phase II designs, and overcoming the challenges of array data. Although this book focuses on cancer trials, the same issues and concepts are important in any clinical setting. As always, the authors use clear, lucid prose and a multitude of real-world examples to convey the principles of successful trials without the need for a strong statistics or mathematics background. Armed with Clinical Trials in Oncology, Third Edition, clinicians and statisticians can avoid the many hazards that can jeopardize the success of a trial.

Targeted Therapy in Translational Cancer Research

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1118468686
Total Pages : 398 pages
Book Rating : 4.1/5 (184 download)

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Book Synopsis Targeted Therapy in Translational Cancer Research by : Apostolia-Maria Tsimberidou

Download or read book Targeted Therapy in Translational Cancer Research written by Apostolia-Maria Tsimberidou and published by John Wiley & Sons. This book was released on 2015-10-08 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: Targeted Therapy in Translational Cancer Research for the Translational Oncology series provides a comprehensive overview of recent developments in our understanding of tumor biology, elucidates the roles of targets and pathways involved in carcinogenesis, and describes current state-of-the-art anticancer therapy, as well as the most promising areas of translational research and targeted therapy. Introduces cutting-edge ‘bench to bedside and back’ breakthroughs which have transformed the diagnosis, prognosis, and treatment of cancer Covers basic principles of targeted therapy, including immunotherapy and the roles of cancer stem cells, the microenvironment, angiogenesis, epigenetics, microRNAs, and functional imaging in precision medicine Summarises major advances in therapeutic management of hematologic malignancies and solid tumors using conventional therapy, targeted therapy, immunotherapy, or novel treatment modalities

Targeting Signaling Pathways in Solid Tumors Part A

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Author :
Publisher : Elsevier
ISBN 13 : 0443235473
Total Pages : 276 pages
Book Rating : 4.4/5 (432 download)

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Book Synopsis Targeting Signaling Pathways in Solid Tumors Part A by :

Download or read book Targeting Signaling Pathways in Solid Tumors Part A written by and published by Elsevier. This book was released on 2024-04-23 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: Targeting Signaling Pathways in Solid Tumors, Part A, Volume 385 in the International Review of Cell and Molecular Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Drugging the Undruggable: Advances in Targeting KRAS Signaling in Solid Tumors, Emerging Trends in Gastrointestinal Cancers: Targeting Developmental Pathways in their Carcinogenesis and Tumor Progression, Importance of targeting various cell signaling pathways in solid cancers, Targeting signaling pathways in cancer stem cells: a potential approach for developing novel anticancer therapeutics, Factors affecting heterogeneity in breast cancer microenvironment: A narrative review, and much more. Additional sections cover Exploring TLR Signaling Pathways as Promising Targets in Cervical Cancer: The Road Less Travelled Provides the latest information on cancer research Offers outstanding and original reviews on a range of cancer research topics Serves as an indispensable reference for researchers and students alike

Childhood Cancer and Functional Impacts Across the Care Continuum

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Author :
Publisher :
ISBN 13 : 9780309683494
Total Pages : pages
Book Rating : 4.6/5 (834 download)

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Book Synopsis Childhood Cancer and Functional Impacts Across the Care Continuum by : National Academies of Sciences Engineering and Medicine

Download or read book Childhood Cancer and Functional Impacts Across the Care Continuum written by National Academies of Sciences Engineering and Medicine and published by . This book was released on 2021-09-09 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the late 1960s, the survival rate in children and adolescents diagnosed with cancer has steadily improved, with a corresponding decline in the cancer-specific death rate. Although the improvements in survival are encouraging, they have come at the cost of acute, chronic, and late adverse effects precipitated by the toxicities associated with the individual or combined use of different types of treatment (e.g., surgery, radiation, chemotherapy). In some cases, the impairments resulting from cancer and its treatment are severe enough to qualify a child for U.S. Social Security Administration disability benefits. At the request of Social Security Administration, Childhood Cancer and Functional Impacts Across the Care Continuum provides current information and findings and conclusions regarding the diagnosis, treatment, and prognosis of selected childhood cancers, including different types of malignant solid tumors, and the effect of those cancers on childrenâ (TM)s health and functional capacity, including the relative levels of functional limitation typically associated with the cancers and their treatment. This report also provides a summary of selected treatments currently being studied in clinical trials and identifies any limitations on the availability of these treatments, such as whether treatments are available only in certain geographic areas.

Practical Geriatric Oncology

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Author :
Publisher : Cambridge University Press
ISBN 13 : 1139490591
Total Pages : pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Practical Geriatric Oncology by : Arti Hurria

Download or read book Practical Geriatric Oncology written by Arti Hurria and published by Cambridge University Press. This book was released on 2010-09-13 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The risk of cancer increases with age, and the number of older adults seeking treatment is increasing dramatically in line with the aging population. The care of older patients differs from that of younger adults because of differences in the biology of the tumor, age-related differences in host physiology, comorbidity burden and psychosocial issues, which might impact the efficacy and side effects of cancer therapy. Practical Geriatric Oncology is a comprehensive, evidence-based text that synthesizes the growing literature in this field and provides practical guidelines to the care of older adults with cancer. Coverage includes patient assessment, management of solid tumors and hematologic malignancies, the impact of age on the pharmacology of cancer therapy, surgical oncology and radiation oncology in the older adult, symptom management and supportive care. In addition to serving as core reading for oncologists and hematologists, the book will also be a useful work for other healthcare professionals who provide oncology care, including surgeons, radiation oncologists, palliative care doctors, primary care providers, geriatricians and nurses.

The EBMT/EHA CAR-T Cell Handbook

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Author :
Publisher : Springer Nature
ISBN 13 : 3030943534
Total Pages : 221 pages
Book Rating : 4.0/5 (39 download)

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Book Synopsis The EBMT/EHA CAR-T Cell Handbook by : Nicolaus Kröger

Download or read book The EBMT/EHA CAR-T Cell Handbook written by Nicolaus Kröger and published by Springer Nature. This book was released on 2022-02-07 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: This first open access European CAR-T Handbook, co-promoted by the European Society for Blood and Marrow Transplantation (EBMT) and the European Hematology Association (EHA), covers several aspects of CAR-T cell treatments, including the underlying biology, indications, management of side-effects, access and manufacturing issues. This book, written by leading experts in the field to enhance readers’ knowledge and practice skills, provides an unparalleled overview of the CAR-T cell technology and its application in clinical care, to enhance readers’ knowledge and practice skills.

Molecularly Targeted Therapy for Childhood Cancer

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Author :
Publisher : Springer
ISBN 13 : 9780387690605
Total Pages : 536 pages
Book Rating : 4.6/5 (96 download)

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Book Synopsis Molecularly Targeted Therapy for Childhood Cancer by : Peter J. Houghton

Download or read book Molecularly Targeted Therapy for Childhood Cancer written by Peter J. Houghton and published by Springer. This book was released on 2010-09-08 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: Each chapter will focus on the known molecular characteristics of specific childhood cancers, focusing on how the molecular ‘drivers’ can be exploited from a therapeutic standpoint with currently available targeted agents. Where applicable, integration of targeted therapies with conventional cytotoxic agents will be considered. This volume will provide a comprehensive summary of molecular characteristics of childhood cancers, and how the changes involved in transformation provide us with opportunities for developing relatively less toxic, but curative, therapies.

Successes and Limitations of Targeted Cancer Therapy

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Author :
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318025429
Total Pages : 126 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Successes and Limitations of Targeted Cancer Therapy by : S. Peters

Download or read book Successes and Limitations of Targeted Cancer Therapy written by S. Peters and published by Karger Medical and Scientific Publishers. This book was released on 2014-02-19 with total page 126 pages. Available in PDF, EPUB and Kindle. Book excerpt: The treatment of patients with advanced malignancies has undergone remarkable change in the last few years. While in the past decisions about systemic therapy were largely based on the performance status of a patient, oncologists today also take into account the pathological and molecular characteristics of the patient’s tumor. Targeting specific molecular pathways important for tumorigenesis has become the preferred way of treatment for many types of malignancies. With these advances come new challenges including the optimization of therapy, recognizing and dealing with side effects and, importantly, the development of resistance. This book provides an up-to-date overview of the advances and limitations of targeted therapy for several tumor entities including breast cancer, colon cancer, gastrointestinal stromal tumors, lung cancer, melanoma, ovarian cancer and renal cell carcinoma. Written by over a dozen internationally renowned scientists, the book is suitable for advanced students, postdoctoral researchers, scientists and clinicians who wish to update their knowledge of the latest approaches to targeted cancer therapies.

Fast Facts: Molecular Profiling in Solid Tumors

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Author :
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318070750
Total Pages : 104 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Fast Facts: Molecular Profiling in Solid Tumors by : Parneet Cheema

Download or read book Fast Facts: Molecular Profiling in Solid Tumors written by Parneet Cheema and published by Karger Medical and Scientific Publishers. This book was released on 2022-11-14 with total page 104 pages. Available in PDF, EPUB and Kindle. Book excerpt: Identifying tumor-specific molecular aberrations via molecular profiling is vital for the use of targeted therapies. Understanding a patient’s unique tumor genetics provides predictive and prognostic information that enables a personalized care plan to be put in place, improving outcomes and minimizing ineffective treatments. 'Fast Facts: Molecular Profiling in Solid Tumors' provides a firm knowledge foundation of somatic molecular profiling methodologies, key information to help with the use of molecular profiling in daily practice and advice on communicating with patients about molecular testing and results. Table of Contents: • Molecular profiling: the basics • Rationale for testing • Sample collection • Test selection and process • Interpreting the report • Talking to patients • Challenges and opportunities