Author : Hong Liang Tey
Publisher : Frontiers Media SA
ISBN 13 : 283254939X
Total Pages : 100 pages
Book Rating : 4.8/5 (325 download)
Book Synopsis Targeted Immunological Therapies in Dermatology by : Hong Liang Tey
Download or read book Targeted Immunological Therapies in Dermatology written by Hong Liang Tey and published by Frontiers Media SA. This book was released on 2024-05-23 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cutaneous inflammation, particularly for chronic inflammatory diseases such as eczema and psoriasis are traditionally treated with corticosteroids to control ongoing inflammation. However, prolonged usage of steroids can lead to various side-effects such as thinning of skin, stretch marks or easy bruising. Prolonged suppression of the immune system may also result in secondary infections, driving more inflammation. Next-generation targeted immunological therapies can thus provide an alternative way for us to treat cutaneous inflammation in a more precise manner; these therapies are often wide-ranging in nature, encompassing biologics, small-molecule inhibitors or RNA therapeutics. Through this research topic, we hope to highlight recent developments in understanding dysregulations in the cutaneous immune system with a special focus on dermatitis, and how this knowledge informs development of next-generation targeted therapies. We are especially interested in methods and models for assessing therapeutic efficacy; drug delivery and formulation methods circumventing the epithelial barrier and maintaining molecule stability. Concurrently, we hope to highlight outstanding gaps in the field currently that may require further therapeutic development.