The Alkali Metal Ions: Their Role for Life

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Publisher : Springer
ISBN 13 : 3319217569
Total Pages : 663 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis The Alkali Metal Ions: Their Role for Life by : Astrid Sigel

Download or read book The Alkali Metal Ions: Their Role for Life written by Astrid Sigel and published by Springer. This book was released on 2016-02-09 with total page 663 pages. Available in PDF, EPUB and Kindle. Book excerpt: MILS-16 provides an up-to-date review of the impact of alkali metal ions on life. Their bioinorganic chemistry and analytical determination, the solid state structures of bio-ligand complexes and the properties of alkali metal ions in solution in the context of all kinds of biologically relevant ligands are covered, this includes proteins (enzymes) and nucleic acids (G-quadruplexes). Minerals containing sodium (Na+) and potassium (K+) are abundant in the Earth's crust, making Na+ and K+ easily available. In contrast, the alkali elements lithium (Li+), rubidium, and cesium are rare and the radioactive francium occurs only in traces. Since the intra- and extracellular, as well as the compartmental concentrations of Na+ and K+ differ significantly, homeostasis and active transport of these ions are important; this involves transporters/carriers and pore-forming ion channel proteins. Systems like Na+/K+-ATPases, H+/K+-ATPases or Na+/H+ antiporters are thoroughly discussed. The role of K+ in photosynthesis and the role of Na+ in charging the "battery of life" are pointed out. Also, the relationships between alkali metal ions and diseases (e.g., Parkinson or traumatic brain injury) are covered and the relevance of Li+ salts in medicine (pharmacology and mechanism) is reviewed. This and more is treated in an authoritative and timely manner in the 16 stimulating chapters of Volume 16, The Alkali Metal Ions: Their Role for Life, which are written by 44 internationally recognized experts from 12 nations. The impact of this vibrant research area is manifested in nearly 3000 references, over 30 tables and more than 150 illustrations (two thirds in color). MILS-16 also provides excellent information for teaching. Astrid Sigel, Helmut Sigel, and Roland K. O. Sigel have long-standing interests in Biological Inorganic Chemistry. Their research focuses on metal ion interactions with nucleotides and nucleic acids and on related topics. They edited previously 44 volumes in the series Metal Ions in Biological Systems.

Progress in Inorganic Chemistry, Volume 50

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Publisher : John Wiley & Sons
ISBN 13 : 047146077X
Total Pages : 641 pages
Book Rating : 4.4/5 (714 download)

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Book Synopsis Progress in Inorganic Chemistry, Volume 50 by : Kenneth D. Karlin

Download or read book Progress in Inorganic Chemistry, Volume 50 written by Kenneth D. Karlin and published by John Wiley & Sons. This book was released on 2004-03-24 with total page 641 pages. Available in PDF, EPUB and Kindle. Book excerpt: This series provides inorganic chemists and materials scientists with a forum for critical, authoritative evaluations of advances in every area of the discipline. Volume 50 continues to report recent advances with a significant, up-to-date selection of contributions on topics such as the following: Structural and mechanistic investigations in asymmetric copper; Catalyzed reactions; Phenoxyl radical complexes; Synthesis of large pore zeolites and molecular sieves; Inorganic nanoclusters with fullerene-like structure and nanotubes

American Doctoral Dissertations

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Publisher :
ISBN 13 :
Total Pages : 784 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis American Doctoral Dissertations by :

Download or read book American Doctoral Dissertations written by and published by . This book was released on 1998 with total page 784 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Inorganic and Organometallic Transition Metal Complexes with Biological Molecules and Living Cells

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Publisher : Academic Press
ISBN 13 : 012803887X
Total Pages : 408 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Inorganic and Organometallic Transition Metal Complexes with Biological Molecules and Living Cells by : Kenneth Kam-Wing Lo

Download or read book Inorganic and Organometallic Transition Metal Complexes with Biological Molecules and Living Cells written by Kenneth Kam-Wing Lo and published by Academic Press. This book was released on 2016-12-30 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inorganic and Organometallic Transition Metal Complexes with Biological Molecules and Living Cells provides a complete overview of this important research area that is perfect for both newcomers and expert researchers in the field. Through concise chapters written and edited by esteemed experts, this book brings together a comprehensive treatment of the area previously only available through scattered, lengthy review articles in the literature. Advanced topics of research are covered, with particular focus on recent advances in the biological applications of transition metal complexes, including inorganic medicine, enzyme inhibitors, antiparasital agents, and biological imaging reagents. - Geared toward researchers and students who seek an introductory overview of the field, as well as researchers working in advanced areas - Focuses on the interactions of inorganic and organometallic transition metal complexes with biological molecules and live cells - Foscuses on the fundamentals and their potential therapeutic and diagnostic applications - Covers recent biological applications of transition metal complexes, such as anticancer drugs, enzyme inhibitors, bioconjugation agents, chemical biology tools, and bioimaging reagents

Metal-based Anticancer Agents

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Publisher : Royal Society of Chemistry
ISBN 13 : 1788017676
Total Pages : 370 pages
Book Rating : 4.7/5 (88 download)

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Book Synopsis Metal-based Anticancer Agents by : Angela Casini

Download or read book Metal-based Anticancer Agents written by Angela Casini and published by Royal Society of Chemistry. This book was released on 2019-04-05 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metal-based anticancer drugs are among the most successful therapeutic agents, as evidenced by the frequent prescription of selected platinum and arsenic compounds to patients. Metal-based Anticancer Agents covers the interdisciplinary world of inorganic drug discovery and development by introducing the most prominent compound classes based on different transition metals, discussing emerging concepts and enabling methods, as well as presenting key pre-clinical and clinical aspects. Recent progress on the unique features of next-generation targeted metal-based anticancer agents, including supramolecular coordination complexes used for both therapy and drug delivery, promise a bright future beyond the benefits of pure cytotoxic activity. With contributions from global leaders in the field, this book will serve as a useful reference to established researchers as well as a practical guide to those new to metallodrugs, and postgraduate students of medicinal chemistry and metallobiology.

Scientific and Technical Aerospace Reports

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Publisher :
ISBN 13 :
Total Pages : 1452 pages
Book Rating : 4.:/5 (31 download)

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Book Synopsis Scientific and Technical Aerospace Reports by :

Download or read book Scientific and Technical Aerospace Reports written by and published by . This book was released on 1968 with total page 1452 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy

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Publisher : Springer Science & Business Media
ISBN 13 : 030644027X
Total Pages : 563 pages
Book Rating : 4.3/5 (64 download)

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Book Synopsis Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy by : Stephen B. Howell

Download or read book Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy written by Stephen B. Howell and published by Springer Science & Business Media. This book was released on 1991 with total page 563 pages. Available in PDF, EPUB and Kindle. Book excerpt: Taken together the data presented in this review, and work by many other investigators, support the notion that DNA excision repair is important in a tumor cell's resistance to platinum compounds. Inhibition of this repair system by combination chemotherapy with the excision repair inhibitors HU and Ara-C produces synergistic cell kills and increased levels and persistance of DNA interstrand crosslinks. The studies with cis-DDP and ~-DDP in combination with UV induced thymine dimers suggest that there may be competition for DNA repair enzymes between the dimer and the platinum lesion. Whether the competing lesion is an intrastrand crosslink, interstrand crosslink, or platinum monoadduct (or all of these lesions) cannot be determined. The similarity between an intrastrand crosslink and a cyclobutane dimer suggests that these lesions may compete for repair. However, the increased peak levels of interstrand crosslinks, and increased persistence of these lesions at later time points suggest that this lesion may also be a substrate for the repair system. These observations may be of clinical relevance. Recently Dr. Kathy Albain of our institution has completed a Phase III I study using a 12 hour pretreatment with HU and Ara-C in patients prior to their cis-DDP therapy. She observed a significant number of responders in this trial (54). She is currently completing a second Phase IIII study substituting IV HU for the oral formulation. We anticipate initiating other clinical trials based upon these observations.

Comprehensive Coordination Chemistry II

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Publisher : Newnes
ISBN 13 : 0080913164
Total Pages : 11845 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Comprehensive Coordination Chemistry II by : J. A. McCleverty

Download or read book Comprehensive Coordination Chemistry II written by J. A. McCleverty and published by Newnes. This book was released on 2003-12-03 with total page 11845 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Coordination Chemistry II (CCC II) is the sequel to what has become a classic in the field, Comprehensive Coordination Chemistry, published in 1987. CCC II builds on the first and surveys new developments authoritatively in over 200 newly comissioned chapters, with an emphasis on current trends in biology, materials science and other areas of contemporary scientific interest.

Hydrogen Transfer Reactions

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Publisher : Springer
ISBN 13 : 3319430513
Total Pages : 393 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Hydrogen Transfer Reactions by : Gabriela Guillena

Download or read book Hydrogen Transfer Reactions written by Gabriela Guillena and published by Springer. This book was released on 2016-09-27 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt: The series Topics in Current Chemistry Collections presents critical reviews from the journal Topics in Current Chemistry organized in topical volumes. The scope of coverage is all areas of chemical science including the interfaces with related disciplines such as biology, medicine and materials science. The goal of each thematic volume is to give the non-specialist reader, whether in academia or industry, a comprehensive insight into an area where new research is emerging which is of interest to a larger scientific audience. Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years are presented using selected examples to illustrate the principles discussed. The coverage is not intended to be an exhaustive summary of the field or include large quantities of data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Contributions also offer an outlook on potential future developments in the field.

Platinum, Gold, and Other Metal Chemotherapeutic Agents

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Publisher :
ISBN 13 : 9780841207585
Total Pages : 470 pages
Book Rating : 4.2/5 (75 download)

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Book Synopsis Platinum, Gold, and Other Metal Chemotherapeutic Agents by : Stephen J. Lippard

Download or read book Platinum, Gold, and Other Metal Chemotherapeutic Agents written by Stephen J. Lippard and published by . This book was released on 1983 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt: Good,No Highlights,No Markup,all pages are intact, Slight Shelfwear,may have the corners slightly dented, may have slight color changes/slightly damaged spine.

2000 International Chemical Congress of Pacific Basin Societies

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Publisher :
ISBN 13 :
Total Pages : 170 pages
Book Rating : 4.0/5 ( download)

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Book Synopsis 2000 International Chemical Congress of Pacific Basin Societies by :

Download or read book 2000 International Chemical Congress of Pacific Basin Societies written by and published by . This book was released on 2000 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Supramolecular Chemistry in the 3rd Millennium

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Publisher : MDPI
ISBN 13 : 3036514635
Total Pages : 264 pages
Book Rating : 4.0/5 (365 download)

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Book Synopsis Supramolecular Chemistry in the 3rd Millennium by : Catherine E. Housecroft

Download or read book Supramolecular Chemistry in the 3rd Millennium written by Catherine E. Housecroft and published by MDPI. This book was released on 2021-08-18 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Special Issue is one of the first for the new MDPI flagship journal Chemistry (ISSN 2624-8549) which has a broad remit for publishing original research in all areas of chemistry. The theme of this issue is Supramolecular Chemistry in the 3rd Millennium and I am sure that this topic will attract many exciting contributions. We chose this topic because it encompasses the unity of contemporary pluridisciplinary science, in which organic, inorganic, physical and theoretical chemists work together with molecular biologists and physicists to develop a systems-level understanding of molecular interactions. The description of supramolecular chemistry as 'chemistry beyond the molecule' (Jean-Marie Lehn, Nobel Lecture and Gautam R. Desiraju, Nature, 2001, 412, 397) addresses the wide variety of weak, non-covalent interactions that are the basis for the assembly of supramolecular architectures, molecular receptors and molecular recognition, programed molecular systems, dynamic combinatorial libraries, coordination networks and functional supramolecular materials. We welcome submissions from all disciplines involved in this exciting and evolving area of science.

Bioorganometallics

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Publisher : John Wiley & Sons
ISBN 13 : 3527607110
Total Pages : 462 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Bioorganometallics by : Gérard Jaouen

Download or read book Bioorganometallics written by Gérard Jaouen and published by John Wiley & Sons. This book was released on 2006-05-12 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: This first comprehensive book to cover the expanding field of bioorganometallics represents the perfect starting point for beginners but also an excellent source of high quality information for experts in the field. Edited by a pioneer in the field with an excellent standing within the community, this book begins with the history of bioorganometallics, before going on to cover pharmaceuticals, bioorganometallic chemistry and radiopharmaceuticals. A must for bioinorganic chemists, the pharmaceutical industry, chemists working in organometallics and biochemists.

Index to Theses with Abstracts Accepted for Higher Degrees by the Universities of Great Britain and Ireland and the Council for National Academic Awards

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Publisher :
ISBN 13 :
Total Pages : 338 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Index to Theses with Abstracts Accepted for Higher Degrees by the Universities of Great Britain and Ireland and the Council for National Academic Awards by :

Download or read book Index to Theses with Abstracts Accepted for Higher Degrees by the Universities of Great Britain and Ireland and the Council for National Academic Awards written by and published by . This book was released on 2006 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Core Concepts in Supramolecular Chemistry and Nanochemistry

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Publisher : John Wiley & Sons
ISBN 13 : 9780470858707
Total Pages : 320 pages
Book Rating : 4.8/5 (587 download)

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Book Synopsis Core Concepts in Supramolecular Chemistry and Nanochemistry by : Jonathan W. Steed

Download or read book Core Concepts in Supramolecular Chemistry and Nanochemistry written by Jonathan W. Steed and published by John Wiley & Sons. This book was released on 2007-04-30 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Supramolecular chemistry and nanochemistry are two strongly interrelated cutting edge frontiers in research in the chemical sciences. The results of recent work in the area are now an increasing part of modern degree courses and hugely important to researchers. Core Concepts in Supramolecular Chemistry and Nanochemistry clearly outlines the fundamentals that underlie supramolecular chemistry and nanochemistry and takes an umbrella view of the whole area. This concise textbook traces the fascinating modern practice of the chemistry of the non-covalent bond from its fundamental origins through to it expression in the emergence of nanochemistry. Fusing synthetic materials and supramolecular chemistry with crystal engineering and the emerging principles of nanotechnology, the book is an ideal introduction to current chemical thought for researchers and a superb resource for students entering these exciting areas for the first time. The book builds from first principles rather than adopting a review style and includes key references to guide the reader through influential work. supplementary website featuring powerpoint slides of the figures in the book further references in each chapter builds from first principles rather than adopting a review style includes chapter on nanochemistry clear diagrams to highlight basic principles

Ruthenium Oxidation Complexes

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Publisher : Springer Science & Business Media
ISBN 13 : 1402093780
Total Pages : 274 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Ruthenium Oxidation Complexes by : William P. Griffith

Download or read book Ruthenium Oxidation Complexes written by William P. Griffith and published by Springer Science & Business Media. This book was released on 2010-11-03 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ruthenium Oxidation Complexes explores ruthenium complexes, particularly those in higher oxidation states, which function as useful and selective organic oxidation catalysts. Particular emphasis is placed on those systems which are of industrial significance. The preparation, properties and applications of the ruthenium complexes are described, followed by a presentation of their oxidative properties and summary of the different mechanisms involved in the organic oxidations (e.g. oxidations of alcohols, alkenes, arenes and alkynes, alkanes, amines, ethers, phopshines and miscellaneous substrates). Moreover, future trends and developments in the area are discussed. This monograph is aimed at inorganic, organic, industrial and catalysis chemists, especially those who wish to carry out specific organic oxidations using catalytic methods.

Advanced Organic Chemistry

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Publisher : Springer Science & Business Media
ISBN 13 : 0387448993
Total Pages : 1216 pages
Book Rating : 4.3/5 (874 download)

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Book Synopsis Advanced Organic Chemistry by : Francis A. Carey

Download or read book Advanced Organic Chemistry written by Francis A. Carey and published by Springer Science & Business Media. This book was released on 2007-06-27 with total page 1216 pages. Available in PDF, EPUB and Kindle. Book excerpt: The two-part, fifth edition of Advanced Organic Chemistry has been substantially revised and reorganized for greater clarity. The material has been updated to reflect advances in the field since the previous edition, especially in computational chemistry. Part A covers fundamental structural topics and basic mechanistic types. It can stand-alone; together, with Part B: Reaction and Synthesis, the two volumes provide a comprehensive foundation for the study in organic chemistry. Companion websites provide digital models for study of structure, reaction and selectivity for students and exercise solutions for instructors.