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Synthesis Of Lactam Antibiotics
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Book Synopsis Synthesis of β-Lactam Antibiotics by : Alle Bruggink
Download or read book Synthesis of β-Lactam Antibiotics written by Alle Bruggink and published by Springer Science & Business Media. This book was released on 2011-06-27 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Penicillins and cephalosporins have a long history in combating bacterial infections. Despite new infectious diseases and occurring resistance, beta-lactam antibiotics will for many years to come continue to play a prominent role in our therapeutic arsenal. This book covers the industrial development of the chemical and biochemical processes used to manufacture these products, as well as looking ahead to possible future processes. The interplay between synthetic organic chemistry with the understanding and application of enzymes, modeling of fermentation processes and integration through (bio-) chemical process engineering is illustrated. In-depth scientific approaches to biocatalysis and biocatalyst development including enzyme kinetics, enzyme crystal studies and semi-rational enzyme mutations are also presented. Metabolic pathway analysis and modeling of fermentation process are treated as well as molecular precision in synthetic approaches to beta-lactams, their precursors and derivatives. Process technology studies including new reactor concepts, possible short-cut routes and improved down-stream-processing methods complete a broad view on the scope and limitations of the presently developed industrial processes including an intriguing insight into future process possibilities. This book represents an excellent case study on the transformation of traditional, stoïchiometric, organic synthesis and classical fermentations into modern (bio-) catalysis and biosynthesis based on insights in metabolic pathways and enzyme actions.
Book Synopsis Chemistry and Biology of [beta]-lactam Antibiotics by : Robert B. Morin
Download or read book Chemistry and Biology of [beta]-lactam Antibiotics written by Robert B. Morin and published by . This book was released on 1982 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Synthesis of Beta-lactam Antibiotics :chemistry, Biocatalysis & Process Integration by :
Download or read book Synthesis of Beta-lactam Antibiotics :chemistry, Biocatalysis & Process Integration written by and published by . This book was released on 2001 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Approaches to the Synthesis of Beta -lactam Antibiotics by : T. H. Khan
Download or read book Approaches to the Synthesis of Beta -lactam Antibiotics written by T. H. Khan and published by . This book was released on 1987 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Synthesis of the Beta-lactam Antibiotics and Peptides by : Mankil Jung
Download or read book Synthesis of the Beta-lactam Antibiotics and Peptides written by Mankil Jung and published by . This book was released on 1978 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Chemistry of β-Lactams by : M.I. Page
Download or read book The Chemistry of β-Lactams written by M.I. Page and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is over sixty years since Alexander Fleming observed antibiosis between a Penicillium mould and bacterial cultures and gave the name penicillin to the active principle. Although it was proposed in 1943 that penicillin (1) contained a tJ-Iactam ring, this was not generally accepted until an X-ray crystallographic determination of the structure had been completed. RCONH )=r)
Book Synopsis Recent Progress in the Chemical Synthesis of Antibiotics by : Gabor Lukacs
Download or read book Recent Progress in the Chemical Synthesis of Antibiotics written by Gabor Lukacs and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 808 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of antibiotics in the treatment by antibacterial and antifungal chemo therapy, has become standard practice since the end of World War Two and has had an enormous impact on healthcare throughout the world. Compounds belonging to this class have also reached an important place in the medical treatment of human cancer. Although, the discovery of most of these agents came from more or less sophisticated screening programs of soil microrganisms, many of the important antibiotics used today in clinical practice are derived from the original biosynthetic products by the application of often novel and generally elaborated chemical synthetic methodologies. In fact the antibiotics have represented (and still represent) for a generation of organic chemists an endless source of molecular structures whose varied assemblage of carbon atom backbones and chemical functions was beyond any possibility of imagination. Perhaps a similar repertoire of chemotypes was formerly offered by the natural products, namely the alkaloids, the terpenes, the vitamins and hormones as well as the pigments of the animal and plant kingdoms, albeit the chemical arrange ments of the antibiotic molecules appeared much more surprising and diverse to the admiring eyes of cultivated organic chemists. The idea of this book, certainly a landmark in the field, came during the Symposium of EUCHEM on Chemical Synthesis of Antibiotics, that was held at Aussois in Savoy, France (May 2-6, 1988), the initiative being taken by Gabor Lukacs to whom Masaji Ohno readily associated as a co-editor.
Book Synopsis Some Approaches Towards the Synthesis of Beta-lactam Antibiotics by : J. Cuffe
Download or read book Some Approaches Towards the Synthesis of Beta-lactam Antibiotics written by J. Cuffe and published by . This book was released on 1983 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Stereospecific Synthesis of [beta]-lactam Antibiotics from Peptide Precursors by : Stephen Barry Haber
Download or read book The Stereospecific Synthesis of [beta]-lactam Antibiotics from Peptide Precursors written by Stephen Barry Haber and published by . This book was released on 1976 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Design and Synthesis of Novel [beta]-Lactam Antibiotics by : Wenlin Lee
Download or read book Design and Synthesis of Novel [beta]-Lactam Antibiotics written by Wenlin Lee and published by . This book was released on 2001 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Stereospecific Total Synthesis of Beta-lactam Antibiotics from Peptide Precursors by : Michael Allen Christie
Download or read book Stereospecific Total Synthesis of Beta-lactam Antibiotics from Peptide Precursors written by Michael Allen Christie and published by . This book was released on 1978 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis New Synthetic Methods for the Synthesis of BETA -lactam Antibiotics by : J. Knight
Download or read book New Synthetic Methods for the Synthesis of BETA -lactam Antibiotics written by J. Knight and published by . This book was released on 1986 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Oral Cephalosporins by : Robert C. Moellering
Download or read book Oral Cephalosporins written by Robert C. Moellering and published by S Karger Ag. This book was released on 1995 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides an excellent survey of the chemistry, microbiology, pharmacology and clinical use of the oral cephalosporins in general and the newer agents in particular. The cephalosporins have long provided satisfactory treatment for many disorders without causing serious side effects; and over the past fifty years forms with different antimicrobial, pharmacologic and toxicologic properties have been developed. Despite the broad spectrum of their activity against a large variety of gram-positive and gram-negative bacteria, the third-generation oral cephalosporins including the prodrug esters do not work against Pseudomonas aeruginosa, methicillin-resistant staphylococci, enterococci or Bacteroides species. Many, however, are suitable for treating infections of the respiratory and urinary tracts and of the skin and its structure, as well as certain sexually-transmitted diseases. Authors consider other possible uses, against multi-resistant Enterobacteriaceae for instance, but also point out the limitations of the oral cephalosporins. For those working in the fields of infectious disease, bacteriology, chemotherapy, pharmaceutics and pharmacokinetics, this book is a valuable source of authoritative information.
Book Synopsis Approaches to the synthesis of β-lactam antibiotics by : Tariq Hussain Khan
Download or read book Approaches to the synthesis of β-lactam antibiotics written by Tariq Hussain Khan and published by . This book was released on 1987 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Total Synthesis of Non-beta-lactam Antibiotics by : Richard Neil Templar Freeman
Download or read book The Total Synthesis of Non-beta-lactam Antibiotics written by Richard Neil Templar Freeman and published by . This book was released on 1990 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Antibiotic Drug Resistance by : José-Luis Capelo-Martínez
Download or read book Antibiotic Drug Resistance written by José-Luis Capelo-Martínez and published by John Wiley & Sons. This book was released on 2019-09-24 with total page 730 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a thorough and authoritative overview of the multifaceted field of antibiotic science – offering guidance to translate research into tools for prevention, diagnosis, and treatment of infectious diseases. Provides readers with knowledge about the broad field of drug resistance Offers guidance to translate research into tools for prevention, diagnosis, and treatment of infectious diseases Links strategies to analyze microbes to the development of new drugs, socioeconomic impacts to therapeutic strategies, and public policies to antibiotic-resistance-prevention strategies
Book Synopsis The Synthesis of Novel Compounds Related to Beta-lactam Antibiotics by : Nina Issam Sakhnini
Download or read book The Synthesis of Novel Compounds Related to Beta-lactam Antibiotics written by Nina Issam Sakhnini and published by . This book was released on 1994 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
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