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Synthesis Characterisation And Antitumour Activity Of Platinum And Ruthenium Complexes Containing Derivatives Of Ethylenediamine Edta And Mercaptoheterocycles
Download Synthesis Characterisation And Antitumour Activity Of Platinum And Ruthenium Complexes Containing Derivatives Of Ethylenediamine Edta And Mercaptoheterocycles full books in PDF, epub, and Kindle. Read online Synthesis Characterisation And Antitumour Activity Of Platinum And Ruthenium Complexes Containing Derivatives Of Ethylenediamine Edta And Mercaptoheterocycles ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Book Synopsis Ruthenium and Other Non-Platinum Metal Complexes in Cancer Chemotherapy by : Etienne Baulieu
Download or read book Ruthenium and Other Non-Platinum Metal Complexes in Cancer Chemotherapy written by Etienne Baulieu and published by Springer Science & Business Media. This book was released on 2013-03-07 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: With contributions by numerous experts
Book Synopsis Ruthenium Chemistry by : Ajay Kumar Mishra
Download or read book Ruthenium Chemistry written by Ajay Kumar Mishra and published by CRC Press. This book was released on 2018-01-17 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will describe Ruthenium complexes as chemotherapeutic agent specifically at tumor site. It has been the most challenging task in the area of cancer therapy. Nanoparticles are now emerging as the most effective alternative to traditional chemotherapeutic approach. Nanoparticles have been shown to be useful in this respect. However, in view of organ system complicacies, instead of using nanoparticles as a delivery tool, it will be more appropriate to synthesize a drug of nanoparticle size that can use blood transport mechanism to reach the tumor site and regress cancer. Due to less toxicity and effective bio-distribution, ruthenium (Ru) complexes are of much current interest. Additionally, lumiscent Ru-complexes can be synthesized in nanoparticle size and can be directly traced at tissue level. The book will contain the synthesis, characterization, and applications of various Ruthenium complexes as chemotherapeutic agents. The book will also cover the introduction to chemotherapy, classification of Ru- complexes with respect to their oxidation states and geometry, Ruthenium complexes of nano size: shape and binding- selectivity, binding of ruthenium complexes with DNA, DNA cleavage studies and cytotoxicity. The present book will be more beneficial to researchers, scientists and biomedical. Current book will empower specially to younger generation to create a new world of ruthenium chemistry in material science as well as in medicines. This book will be also beneficial to national/international research laboratories, and academia with interest in the area of coordination chemistry more especially to the Ruthenium compounds and its applications.
Book Synopsis Ruthenium Complexes by : Alvin A. Holder
Download or read book Ruthenium Complexes written by Alvin A. Holder and published by John Wiley & Sons. This book was released on 2018-02-27 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Edited by a team of highly respected researchers combining their expertise in chemistry, physics, and medicine, this book focuses on the use of rutheniumcontaining complexes in artificial photosynthesis and medicine. Following a brief introduction to the basic coordination chemistry of ruthenium complexes and their synthesis in section one, as well as their photophysical and photochemical properties, the authors discuss in detail the major concepts of artificial photosynthesis and mechanisms of hydrogen production and water oxidation with ruthenium in section two. The third section of the text covers biological properties and important medical applications of ruthenium complexes as therapeutic agents or in diagnostic imaging. Aimed at stimulating research in this active field, this is an invaluable information source for researchers in academia, health research institutes and governmental departments working in the field of organometallic chemistry, green and sustainable chemistry as well as medicine/drug discovery, while equally serving as a useful reference also for scientists in industry.
Book Synopsis Ruthenium Catalysts and Fine Chemistry by : Christian Bruneau
Download or read book Ruthenium Catalysts and Fine Chemistry written by Christian Bruneau and published by Springer Science & Business Media. This book was released on 2004-06-30 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: With contributions by numerous experts
Book Synopsis Synthesis and Anticancer Activity of Metallocene-containing Nucleoside and DNA Analogues by : Media K. Ismail
Download or read book Synthesis and Anticancer Activity of Metallocene-containing Nucleoside and DNA Analogues written by Media K. Ismail and published by . This book was released on 2018 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: After the discovery of cisplatin, the development of metal-containing anticancer drugs has been the subject of much research, with the aim of achieving high activities with minimal side effects. Metallocene derivatives are now common place within this field. Building on work previously published work by the Tucker group on ferrocene-containing nucleoside analogues, further research has now been undertaken to explore structure activity relationships. Firstly, the study has involved changing the substitution pattern through the synthesis of a series of regioisomeric derivatives, while maintaining other parameters. Secondly, the central metal ion has been changed to ruthenium from iron. The series of compounds have been characterised both spectroscopically and electrochemically and have, also been assessed for their anticancer activity in various cell lines. The latter show that both the substitution pattern and the metal ion play an important role in determining the biological properties. The other metallocene compounds, a tetrasubstituted dicytosine ferrocene and two disubstituted ruthenocene derivatives have also been prepared for incorporation into DNA strands by automated synthesis. The resulting oligoes have been characterised by HPLC and mass spectrometry.
