A Life in Science

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Publisher :
ISBN 13 :
Total Pages : 204 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis A Life in Science by : Sydney Brenner

Download or read book A Life in Science written by Sydney Brenner and published by . This book was released on 2001 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Sydney Brenner's 10-on-10: The Chronicles Of Evolution

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Publisher : Wildtype Books
ISBN 13 : 9811197164
Total Pages : 274 pages
Book Rating : 4.8/5 (111 download)

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Book Synopsis Sydney Brenner's 10-on-10: The Chronicles Of Evolution by : Shuzhen Sim

Download or read book Sydney Brenner's 10-on-10: The Chronicles Of Evolution written by Shuzhen Sim and published by Wildtype Books. This book was released on 2018-11-09 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: Humans now wield a greater influence on the planet than any other species in history, and human-developed technologies like genetic engineering and artificial intelligence stand poised to overtake biological evolution. Just how did we arrive at this unique moment in human history, 14 billion years after the birth of the universe Sydney Brenner's 10-on-10: The Chronicles of Evolution brings together 24 prominent scientists and thinkers to trace the story of evolution through ten logarithmic scales of time. Through expert insights, this unique volume considers how humans found our place in the cosmos, and imagines what lies ahead.Published by Wildtype Books and distributed by World Scientific Publishing Co.

Sydney Brenner

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Publisher :
ISBN 13 : 9780879699475
Total Pages : 0 pages
Book Rating : 4.6/5 (994 download)

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Book Synopsis Sydney Brenner by : Errol C. Friedberg

Download or read book Sydney Brenner written by Errol C. Friedberg and published by . This book was released on 2010 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over his long and inspiring career, the Nobel Laureate Sydney Brenner has made some of the most significant and game-changing discoveries in the field of molecular biology. But Brenner's reach has extended well beyond his own research to inspire new generations of young scientists and to promote the development of science and biotechnology around the world. Based on his personal recollections, with contributions and correspondence from his close friends and colleagues, this book tells the lively story, not only of Brenner himself, but of what came to be known as the "golden age" of biology. About the author: Errol C. Friedberg, M.D., is the Senator Betty and Dr. Andy Andujar Distinguished Professor and Chair at the Department of Pathology, University of Texas Southwestern Medical Center at Dallas. A Fellow of the Royal College of Pathologists and recipient of the Rous Whipple Award from the American Society for Investigative Pathology, Friedberg also serves as Editor-in-Chief of the journal DNA Repair. Friedberg is the author of Cancer Answers, Correcting the Blueprint of Life: An Historical Account of the Discovery of DNA Repair Mechanisms, The Writing Life of James D. Watson, and From Rags to Riches: The Phenomenal Rise of The University of Texas Southwestern Medical Center at Dallas. He is also senior author of the textbook DNA Repair & Mutagenesis, and has edited and annotated a series of interviews published as Sydney Brenner: My Life in Science.

In The Spirit Of Science: Lectures By Sydney Brenner On Dna, Worms And Brains

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Publisher : World Scientific
ISBN 13 : 9813271752
Total Pages : 127 pages
Book Rating : 4.8/5 (132 download)

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Book Synopsis In The Spirit Of Science: Lectures By Sydney Brenner On Dna, Worms And Brains by : Sydney Brenner

Download or read book In The Spirit Of Science: Lectures By Sydney Brenner On Dna, Worms And Brains written by Sydney Brenner and published by World Scientific. This book was released on 2018-09-10 with total page 127 pages. Available in PDF, EPUB and Kindle. Book excerpt: In October 2017, Nobel laureate Sydney Brenner (Physiology or Medicine, 2002) gave four lectures on the history of Molecular Biology, its impact on Neuroscience and the great scientific questions that lie ahead.Sydney Brenner has been at the centre of the development of molecular biology, being a key player in shaping the Laboratory for Molecular Biology in Cambridge into a cradle of research, where pioneering and seminal discoveries in the field for over half a century have resulted in more than half a dozen Nobel Prizes.His memory is a treasure trove of the history of the field with innumerable anecdotes on other leading scientists in the past 60 years. These lectures trace the history and recount some of those anecdotes. His interlocutor Terry Sejnowski is the Francis Crick professor at the Salk Institute for Biological Studies and the Laboratory Head of its Computational Neurobiology Laboratory. Terry and Sydney are long-term collaborators and they share many stories and memories.The recorded lectures are the basis for this book. It aims to preserve the history of molecular biology and to also raise scientific questions that have resulted from the work of Sydney, Terry and others. It should be read by everybody who is interested in the generation, history and impact of great ideas as recounted by one of the legends of 20th century science.Published in collaboration with Institute Para Limes.

Loose Ends...false Starts

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Publisher : World Scientific
ISBN 13 : 9811208190
Total Pages : 286 pages
Book Rating : 4.8/5 (112 download)

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Book Synopsis Loose Ends...false Starts by : Sydney Brenner

Download or read book Loose Ends...false Starts written by Sydney Brenner and published by World Scientific. This book was released on 2019-07-16 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sydney Brenner was born in South Africa and educated at the University of Witwatersrand, Johannesburg (Medicine and Science). He then moved to Oxford and received a D.Phil in 1952, before joining the MRC Unit in the Cavendish Laboratory in Cambridge in 1956. His various accomplishments include serving as the Director of MRC Laboratory of Molecular Biology in Cambridge, founding the Molecular Science Institute in Berkeley, holding the position of Distinguished Professor at the Salk Institute, La Jolla. And during his last years, Sydney Brenner played a key role in shaping research and development in the biomedical sector in Singapore as A*Star Senior Fellow.He was one of the greatest biologists of the 20th century and was awarded the Nobel Prize in 2002 for his pioneering work in the field of molecular biology. He was also known for his boundless curiosity, sharp intellect and courage to speak with clarity and characteristic wit as evident in this delightful book which is a compilation of the columns that he wrote for Current Biology in the late '90s.

Fred Sanger - Double Nobel Laureate

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Publisher : Cambridge University Press
ISBN 13 : 1316124053
Total Pages : 315 pages
Book Rating : 4.3/5 (161 download)

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Book Synopsis Fred Sanger - Double Nobel Laureate by : George G. Brownlee

Download or read book Fred Sanger - Double Nobel Laureate written by George G. Brownlee and published by Cambridge University Press. This book was released on 2020-04-02 with total page 315 pages. Available in PDF, EPUB and Kindle. Book excerpt: Considered 'the father of genomics', Fred Sanger (1918–2013) paved the way for the modern revolution in our understanding of biology. His pioneering methods for sequencing proteins, RNA and, eventually, DNA earned him two Nobel Prizes. He remains one of only four scientists (and the only British scientist) ever to have achieved that distinction. In this, the first full biography of Fred Sanger to be published, Brownlee traces Sanger's life from his birth in rural Gloucestershire to his retirement in 1983 from the Medical Research Council's Laboratory of Molecular Biology in Cambridge. Along the way, he highlights the remarkable extent of Sanger's scientific achievements and provides a real portrait of the modest man behind them. Including an extensive transcript of a rare interview of Sanger by the author, this biography also considers the wider legacy of Sanger's work, including his impact on the Human Genome Project and beyond.

Molecular Biology

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Publisher : Academic Press
ISBN 13 :
Total Pages : 654 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Molecular Biology by : Sydney Brenner

Download or read book Molecular Biology written by Sydney Brenner and published by Academic Press. This book was released on 1989 with total page 654 pages. Available in PDF, EPUB and Kindle. Book excerpt: Founded in 1959, by John Kendrew, the Journal of Molecular Biology was the first journal devoted to this new and revolutionary science. To celebrate the thirtieth anniversary of the Journal, the current editor, Sydney Brenner, has selected a number of papers from the first hundred volumes. They include the seminal papers on genetic regulation by Jacob and Monod and on allostery by Monod, Changeux and Jacob. Also included are many important papers on structural biology and molecular genetics and papers reflecting the initial developments in DNA cloning and sequencing. Of value to all biologists with an interest in the molecular basis of living systems, the book is a personal selection by the Editor. Readers are encouraged to compare it with their own choice from the Journal of Molecular Biology.

From Sarah to Sydney

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Publisher : Yale University Press
ISBN 13 : 0300258364
Total Pages : 396 pages
Book Rating : 4.3/5 (2 download)

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Book Synopsis From Sarah to Sydney by : June Cummins

Download or read book From Sarah to Sydney written by June Cummins and published by Yale University Press. This book was released on 2021-06-22 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: The untold life story of All-of-a-Kind Family author Sydney Taylor, highlighting her dramatic influence on American children’s literature This is the first and only biography of Sydney Taylor (1904–1978), author of the award-winning All-of-a-Kind Family series of books, the first juvenile novels published by a mainstream publisher to feature Jewish children characters. The family—based on Taylor’s own as a child—includes five sisters, each two years apart, dressed alike by their fastidious immigrant mother so they all look the same: all-of-a-kind. The four other sisters’ names were the same in the books as in their real lives; only the real-life Sarah changed hers to the boyish Sydney while she was in high school. Cummins elucidates the deep connections between the progressive Taylor’s books and American Jewish experiences, arguing that Taylor was deeply influential in the development of national Jewish identity. This biography conveys the vital importance of children’s books in the transmission of Jewish culture and the preservation of ethnic heritage.

Brenner's Encyclopedia of Genetics

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Publisher : Academic Press
ISBN 13 : 0080961568
Total Pages : 4360 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Brenner's Encyclopedia of Genetics by : Stanley Maloy

Download or read book Brenner's Encyclopedia of Genetics written by Stanley Maloy and published by Academic Press. This book was released on 2013-03-03 with total page 4360 pages. Available in PDF, EPUB and Kindle. Book excerpt: The explosion of the field of genetics over the last decade, with the new technologies that have stimulated research, suggests that a new sort of reference work is needed to keep pace with such a fast-moving and interdisciplinary field. Brenner's Encyclopedia of Genetics, Second Edition, Seven Volume Set, builds on the foundation of the first edition by addressing many of the key subfields of genetics that were just in their infancy when the first edition was published. The currency and accessibility of this foundational content will be unrivalled, making this work useful for scientists and non-scientists alike. Featuring relatively short entries on genetics topics written by experts in that topic, Brenner's Encyclopedia of Genetics, Second Edition, Seven Volume Set provides an effective way to quickly learn about any aspect of genetics, from Abortive Transduction to Zygotes. Adding to its utility, the work provides short entries that briefly define key terms, and a guide to additional reading and relevant websites for further study. Many of the entries include figures to explain difficult concepts. Key terms in related areas such as biochemistry, cell, and molecular biology are also included, and there are entries that describe historical figures in genetics, providing insights into their careers and discoveries. This 7-volume set represents a 25% expansion from the first edition, with over 1600 articles encompassing this burgeoning field Thoroughly up-to-date, with many new topics and subfields covered that were in their infancy or not inexistence at the time of the first edition. Timely coverage of emergent areas such as epigenetics, personalized genomic medicine, pharmacogenetics, and genetic enhancement technologies Interdisciplinary and global in its outlook, as befits the field of genetics Brief articles, written by experts in the field, which not only discuss, define, and explain key elements of the field, but also provide definition of key terms, suggestions for further reading, and biographical sketches of the key people in the history of genetics

DNA Repair and Mutagenesis

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Publisher : American Society for Microbiology Press
ISBN 13 : 1555813194
Total Pages : 2587 pages
Book Rating : 4.5/5 (558 download)

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Book Synopsis DNA Repair and Mutagenesis by : Errol C. Friedberg

Download or read book DNA Repair and Mutagenesis written by Errol C. Friedberg and published by American Society for Microbiology Press. This book was released on 2005-11-22 with total page 2587 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential resource for all scientists researching cellular responses to DNA damage. • Introduces important new material reflective of the major changes and developments that have occurred in the field over the last decade. • Discussed the field within a strong historical framework, and all aspects of biological responses to DNA damage are detailed. • Provides information on covering sources and consequences of DNA damage; correcting altered bases in DNA: DNA repair; DNA damage tolerance and mutagenesis; regulatory responses to DNA damage in eukaryotes; and disease states associated with defective biological responses to DNA damage.

Scientific Freedom

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Publisher : John Wiley & Sons
ISBN 13 : 0470245719
Total Pages : 198 pages
Book Rating : 4.4/5 (72 download)

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Book Synopsis Scientific Freedom by : Donald W. Braben

Download or read book Scientific Freedom written by Donald W. Braben and published by John Wiley & Sons. This book was released on 2008-02-13 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific Freedom outlines what needs to be done to restore the freedom that can transform scientific understanding. The author defines Transformative Research (Venture Research) and explains how an initiative might be designed and implemented; discusses the revolutionary concept of low-risk, high-reward research; explains the wider significance of instability, and introduces the formidable Damocles Zone; explores threats to the university as an institution; and describes how a Transformative Research initiative might work in practice.

The Nematode Caenorhabditis Elegans

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Publisher :
ISBN 13 :
Total Pages : 694 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Nematode Caenorhabditis Elegans by : William Barry Wood

Download or read book The Nematode Caenorhabditis Elegans written by William Barry Wood and published by . This book was released on 1988 with total page 694 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Who Wrote the Book of Life?

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Publisher : Stanford University Press
ISBN 13 : 9780804734172
Total Pages : 476 pages
Book Rating : 4.7/5 (341 download)

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Book Synopsis Who Wrote the Book of Life? by : Lily E. Kay

Download or read book Who Wrote the Book of Life? written by Lily E. Kay and published by Stanford University Press. This book was released on 2000 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a detailed history of one of the most important and dramatic episodes in modern science, recounted from the novel vantage point of the dawn of the information age and its impact on representations of nature, heredity, and society. Drawing on archives, published sources, and interviews, the author situates work on the genetic code (1953-70) within the history of life science, the rise of communication technosciences (cybernetics, information theory, and computers), the intersection of molecular biology with cryptanalysis and linguistics, and the social history of postwar Europe and the United States. Kay draws out the historical specificity in the process by which the central biological problem of DNA-based protein synthesis came to be metaphorically represented as an information code and a writing technology—and consequently as a “book of life.” This molecular writing and reading is part of the cultural production of the Nuclear Age, its power amplified by the centuries-old theistic resonance of the “book of life” metaphor. Yet, as the author points out, these are just metaphors: analogies, not ontologies. Necessary and productive as they have been, they have their epistemological limitations. Deploying analyses of language, cryptology, and information theory, the author persuasively argues that, technically speaking, the genetic code is not a code, DNA is not a language, and the genome is not an information system (objections voiced by experts as early as the 1950s). Thus her historical reconstruction and analyses also serve as a critique of the new genomic biopower. Genomic textuality has become a fact of life, a metaphor literalized, she claims, as human genome projects promise new levels of control over life through the meta-level of information: control of the word (the DNA sequences) and its editing and rewriting. But the author shows how the humbling limits of these scriptural metaphors also pose a challenge to the textual and material mastery of the genomic “book of life.”

The Quest for Corvo

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Publisher : Random House
ISBN 13 : 0241313007
Total Pages : 290 pages
Book Rating : 4.2/5 (413 download)

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Book Synopsis The Quest for Corvo by : A. J. A. Symons

Download or read book The Quest for Corvo written by A. J. A. Symons and published by Random House. This book was released on 2018-03-08 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: 'What had happened to the lost manuscripts, what train of chances took Rolfe to his death in Venice? The Quest continued' One summer afternoon A.J.A. Symons is handed a peculiar, eccentric novel that he cannot forget and, captivated by this unknown masterpiece, determines to learn everything he can about its mysterious author. The object of his search is Frederick Rolfe, self-titled Baron Corvo - artist, rejected candidate for priesthood and author of serially autobiographical fictions - and its story is told in this 'experiment in biography': a beguiling portrait of an insoluble tangle of talents, frustrated ambitions and self-destruction.

Making Genes, Making Waves

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Publisher : Harvard University Press
ISBN 13 : 0674020677
Total Pages : 251 pages
Book Rating : 4.6/5 (74 download)

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Book Synopsis Making Genes, Making Waves by : Jon Beckwith

Download or read book Making Genes, Making Waves written by Jon Beckwith and published by Harvard University Press. This book was released on 2009-07-01 with total page 251 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1969, Jon Beckwith and his colleagues succeeded in isolating a gene from the chromosome of a living organism. Announcing this startling achievement at a press conference, Beckwith took the opportunity to issue a public warning about the dangers of genetic engineering. Jon Beckwith's book, the story of a scientific life on the front line, traces one remarkable man's dual commitment to scientific research and social responsibility over the course of a career spanning most of the postwar history of genetics and molecular biology. A thoroughly engrossing memoir that recounts Beckwith's halting steps toward scientific triumphs--among them, the discovery of the genetic element that turns genes on--as well as his emergence as a world-class political activist, Making Genes, Making Waves is also a compelling history of the major controversies in genetics over the last thirty years. Presenting the science in easily understandable terms, Beckwith describes the dramatic changes that transformed biology between the late 1950s and our day, the growth of the radical science movement in the 1970s, and the personalities involved throughout. He brings to light the differing styles of scientists as well as the different ways in which science is presented within the scientific community and to the public at large. Ranging from the travails of Robert Oppenheimer and the atomic bomb to the Human Genome Project and recent "Science Wars," Beckwith's book provides a sweeping view of science and its social context in the latter half of the twentieth century.

C. elegans

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Publisher : Springer Science & Business Media
ISBN 13 : 1597451517
Total Pages : 292 pages
Book Rating : 4.5/5 (974 download)

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Book Synopsis C. elegans by : Kevin Strange

Download or read book C. elegans written by Kevin Strange and published by Springer Science & Business Media. This book was released on 2008-02-05 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular biology has driven a powerful reductionist, or “molecule-c- tric,” approach to biological research in the last half of the 20th century. Red- tionism is the attempt to explain complex phenomena by defining the functional properties of the individual components of the system. Bloom (1) has referred to the post-genome sequencing era as the end of “naïve reductionism. ” Red- tionist methods will continue to be an essential element of all biological research efforts, but “naïve reductionism,” the belief that reductionism alone can lead to a complete understanding of living organisms, is not tenable. Organisms are clearly much more than the sum of their parts, and the behavior of complex physiological processes cannot be understood simply by knowing how the parts work in isolation. Systems biology has emerged in the wake of genome sequencing as the s- cessor to reductionism (2–5). The “systems” of systems biology are defined over a wide span of complexity ranging from two macromolecules that interact to carry out a specific task to whole organisms. Systems biology is integrative and seeks to understand and predict the behavior or “emergent” properties of complex, multicomponent biological processes. A systems-level characteri- tion of a biological process addresses the following three main questions: (1) What are the parts of the system (i. e.

The Common Thread

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Publisher : Random House
ISBN 13 : 140905800X
Total Pages : 358 pages
Book Rating : 4.4/5 (9 download)

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Book Synopsis The Common Thread by : Georgina Ferry

Download or read book The Common Thread written by Georgina Ferry and published by Random House. This book was released on 2010-12-15 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: John Sulston was director of the Sanger Centre in Cambridge from 1993 to 2000. There he led the British arm of the international team selected to map the entire human DNA sequence, a feat that was pulled off in record time by an extraordinary collaboration of scientists. Despite innumerable setbacks and challenges from outside competitors the ultimate success of the project can be attributed in large part to John Sulston's own determination, passion and scientific excellence. In this personal account he takes us behind the scenes of one of the largest international scientific operations ever undertaken. He is frank about the competition with Craig Venter and Celera Genomics, which threatened to undermine the international community's attempts to make the sequence freely available to everyone. He shares with us his excitement as the project unfolded. And as a pragmatist he reveals his hopes and concerns as to how the information unlocked by the Human Genome Project will affect people's lives in the future. The Common Thread is at once a compelling history of this most exciting of scientific breakthroughs and also an impassioned call for ethical responsibility in scientific research. As the boundaries between science and big business increasingly blur, and researchers race to patent medical discoveries, the international community needs to find a common protocol for the protection of the wider human interest. The Common Thread tells a story of our shared human heritage, offering hope for future research and a fresh outlook on our scientific understanding of ourselves.