The End of Alzheimer's

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Author :
Publisher : Penguin
ISBN 13 : 0735216207
Total Pages : 322 pages
Book Rating : 4.7/5 (352 download)

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Book Synopsis The End of Alzheimer's by : Dale Bredesen

Download or read book The End of Alzheimer's written by Dale Bredesen and published by Penguin. This book was released on 2017-08-22 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: The instant New York Times and Wall Street Journal bestseller A groundbreaking plan to prevent and reverse Alzheimer’s Disease that fundamentally changes how we understand cognitive decline. Everyone knows someone who has survived cancer, but until now no one knows anyone who has survived Alzheimer's Disease. In this paradigm shifting book, Dale Bredesen, MD, offers real hope to anyone looking to prevent and even reverse Alzheimer's Disease and cognitive decline. Revealing that AD is not one condition, as it is currently treated, but three, The End of Alzheimer’s outlines 36 metabolic factors (micronutrients, hormone levels, sleep) that can trigger "downsizing" in the brain. The protocol shows us how to rebalance these factors using lifestyle modifications like taking B12, eliminating gluten, or improving oral hygiene. The results are impressive. Of the first ten patients on the protocol, nine displayed significant improvement with 3-6 months; since then the protocol has yielded similar results with hundreds more. Now, The End of Alzheimer’s brings new hope to a broad audience of patients, caregivers, physicians, and treatment centers with a fascinating look inside the science and a complete step-by-step plan that fundamentally changes how we treat and even think about AD.

The End of Alzheimer's Program

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Author :
Publisher : Penguin
ISBN 13 : 052553850X
Total Pages : 354 pages
Book Rating : 4.5/5 (255 download)

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Book Synopsis The End of Alzheimer's Program by : Dale Bredesen

Download or read book The End of Alzheimer's Program written by Dale Bredesen and published by Penguin. This book was released on 2020-08-18 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: The instant New York Times bestseller The New York Times Best Selling author of The End of Alzheimer's lays out a specific plan to help everyone prevent and reverse cognitive decline or simply maximize brainpower. In The End of Alzheimer's Dale Bredesen laid out the science behind his revolutionary new program that is the first to both prevent and reverse symptoms of Alzheimer's disease. Now he lays out the detailed program he uses with his own patients. Accessible and detailed, it can be tailored to anyone's needs and will enhance cognitive ability at any age. What we call Alzheimer's disease is actually a protective response to a wide variety of insults to the brain: inflammation, insulin resistance, toxins, infections, and inadequate levels of nutrients, hormones, and growth factors. Bredesen starts by having us figure out which of these insults we need to address and continues by laying out a personalized lifestyle plan. Focusing on the Ketoflex 12/3 Diet, which triggers ketosis and lets the brain restore itself with a minimum 12-hour fast, Dr. Bredesen drills down on restorative sleep, targeted supplementation, exercise, and brain training. He also examines the tricky question of toxic exposure and provides workarounds for many difficult problems. The takeaway is that we do not need to do the program perfectly but will see tremendous results if we can do it well enough. With inspiring stories from patients who have reversed cognitive decline and are now thriving, this book shifts the treatment paradigm and offers a new and effective way to enhance cognition as well as unprecedented hope to sufferers of this now no longer deadly disease.

The End of Alzheimer's

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Author :
Publisher : Academic Press
ISBN 13 : 0128121130
Total Pages : 484 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis The End of Alzheimer's by : Thomas J. Lewis

Download or read book The End of Alzheimer's written by Thomas J. Lewis and published by Academic Press. This book was released on 2017-05-12 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: The End of Alzheimer's: The Brain and Beyond, Second Edition is the first comprehensive overview on the molecular basis of Alzheimer's outside of the brain, merging the most recent findings within the field into a single book. It aims to educate the reader on the many overlooked aspects of Alzheimer's disease that occur outside the brain. This book uniquely provides step-by-step, peer-reviewed evidence that the current research model may be misguided and that a new and emerging model is more accurate. It carefully outlines the molecular research in Alzheimer's outside the brain and argues that a more thorough, whole-body diagnosis will provide better answers about its causes and lead to new treatments. It is beneficial to researchers who need to be apprised of the emerging science on the causes of Alzheimer's, and will hopefully redirect many into new avenues of cellular research and discovery. - Comprehensive literature-based summary of the current state of molecular Alzheimer's disease research - Details the shortcomings of the prevailing model and therapeutics in development - Reviews blood-based biomarkers for Alzheimer's and their link to amyloid- and Tau-independent causes outside the brain - Describes the tissues outside the brain impacted by Alzheimer's and the underlying molecular causes - Explains the whole-body risks associated with Alzheimer's, along with concomitant measures to slow or prevent the disease - Provides a protocol to properly research, evaluate, measure, diagnose, and potentially treat Alzheimer's patients

The End of Memory

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Author :
Publisher : Macmillan
ISBN 13 : 1466887915
Total Pages : 296 pages
Book Rating : 4.4/5 (668 download)

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Book Synopsis The End of Memory by : Jay Ingram

Download or read book The End of Memory written by Jay Ingram and published by Macmillan. This book was released on 2015-09-29 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: An illuminating biography of "the plague of the twenty-first century" and scientists' efforts to understand and, they hope, prevent it, The End of Memory is a book for those who want to find out the true story behind an affliction that courses through families and wreaks havoc on the lives of millions. It is a wicked disease that robs its victims of their memories, their ability to think clearly, and ultimately their lives. For centuries, those afflicted by Alzheimer's disease have suffered its debilitating effects while family members sit by, watching their loved ones disappear a little more each day until the person they used to know is gone forever. The disease was first described by German psychologist and neurologist Alois Alzheimer in 1906. One hundred years and a great deal of scientific effort later, much more is known about Alzheimer's, but it still affects millions around the world, and there is no cure in sight. In The End of Memory, award-winning science author Jay Ingram writes a biography of this disease that attacks the brains of patients. He charts the history of the disease from before it was noted by Alois Alzheimer through to the twenty-first century, explains the fascinating science of plaques and tangles, recounts the efforts to understand and combat the disease, and introduces us to the passionate researchers who are working to find a cure.

The Heal Your Gut Cookbook

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Author :
Publisher : Chelsea Green Publishing
ISBN 13 : 1603585621
Total Pages : 322 pages
Book Rating : 4.6/5 (35 download)

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Book Synopsis The Heal Your Gut Cookbook by : Hilary Boynton

Download or read book The Heal Your Gut Cookbook written by Hilary Boynton and published by Chelsea Green Publishing. This book was released on 2014-09-09 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: More than 200 straightforward, nutrient-dense, delicious recipes! “This book provides easy, mouthwatering recipes. It offers practical ways to restore your gut to optimum function, and help you and your family take control of your gut health.”—Dr. Joseph Mercola The Heal Your Gut Cookbook was created by Gut and Psychology Syndrome (GAPS) Diet experts Hilary Boynton and Mary G. Brackett to help heal your gut and to manage the illnesses that stem from it. Pioneering British MD Dr. Natasha Campbell-McBride provides the book’s Foreword. GAPS addresses disorders, including: ADD/ADHD, autism, addictions, depression, and obsessive-compulsive disorder, stemming from or exacerbated by leaky gut and dysbiosis. It also refers to chronic gut-related physical conditions, including: Celiac disease Rheumatoid arthritis Diabetes type one Crohn’s disease Asthma Eczema Allergies Thyroid disorders and more! An evolution of the Specific Carbohydrate Diet, the GAPS Diet will appeal to followers of the Paleo Diet, who are still struggling for optimum health, as well as anyone interested in the health benefits of fermentation or the Weston A. Price approach to nutrition. In The Heal Your Gut Cookbook, readers will learn about the key cooking techniques and ingredients that form the backbone of the GAPS Diet: Working with stocks and broths Soaking nuts and seeds Using coconut Culturing raw dairy The authors offer encouraging, real-life perspectives on the life-changing improvements to the health of their families by following this challenging, but powerful, diet. The GAPS Diet is designed to restore the balance between beneficial and pathogenic intestinal bacteria and seal the gut through the elimination of grains, processed foods, and refined sugars and the carefully sequenced reintroduction of nutrient-dense foods. The Heal Your Gut Cookbook is a must-have if you are following the GAPS Diet, considering the GAPS Diet, or simply looking to improve your digestive health and―by extension―your physical and mental well-being.

Stop Alzheimer's Now!

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Author :
Publisher : Piccadilly Books, Ltd.
ISBN 13 : 0941599981
Total Pages : 352 pages
Book Rating : 4.9/5 (415 download)

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Book Synopsis Stop Alzheimer's Now! by : Bruce Fife

Download or read book Stop Alzheimer's Now! written by Bruce Fife and published by Piccadilly Books, Ltd.. This book was released on 2016-04-11 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over 35 million people have dementia today. Each year 4.6 million new cases occur world-wide -- one new case every 7 seconds. Alzheimer's disease is the most common form of dementia. Parkinson's disease, another progressive brain disorder, affects about 4 million people world-wide. Millions more suffer with other neurodegenerative disorders. The number of people affected by these destructive diseases continues to increase every year. Dementia and other forms of neurodegeneration are not a part of the normal ageing process. The brain is fully capable of functioning normally for a lifetime, regardless of how long a person lives. While ageing is a risk factor for neurodegeneration, it is not the cause! Dementia and other neurodegenerative disorders are disease processes that can be prevented and successfully treated. This book outlines a program using ketone therapy and diet that is backed by decades of medical and clinical research and has proven successful in restoring mental function and improving both brain and overall health. You will learn how to prevent and even reverse symptoms associated with Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis (ALS), multiple sclerosis (MS), Huntington's disease, epilepsy, diabetes, stroke, and various forms of dementia. The information in this book is useful not only for those who are suffering from neurodegenerative disease but for anyone who wants to be spared from ever encountering one or more of these devastating afflictions. These diseases don't just happen overnight. They take years, often decades, to develop. In the case of Alzheimer's disease, approximately 70 percent the brain cells responsible for memory are destroyed before symptoms become noticeable. You can stop Alzheimer's and other neurodegenerative diseases before they take over your life. The best time to start is now.

Still Alice

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Publisher : Simon and Schuster
ISBN 13 : 1439116881
Total Pages : 323 pages
Book Rating : 4.4/5 (391 download)

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Book Synopsis Still Alice by : Lisa Genova

Download or read book Still Alice written by Lisa Genova and published by Simon and Schuster. This book was released on 2009-01-06 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt: Feeling at the top of her game when she is suddenly diagnosed with early onset Alzheimer's Disease, Harvard psychologist Alice Howland struggles to find meaning and purpose in her everyday life as her concept of self gradually slips away. A first novel. Simultaneous.

The First Survivors of Alzheimer's

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Author :
Publisher :
ISBN 13 : 9781432895235
Total Pages : pages
Book Rating : 4.8/5 (952 download)

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Book Synopsis The First Survivors of Alzheimer's by : Bredesen

Download or read book The First Survivors of Alzheimer's written by Bredesen and published by . This book was released on 2022 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: First person stories of patients who recovered from Alzheimer's Disease--and how they did it. It has been said that everyone knows a cancer survivor, but no one has met an Alzheimer's survivor - until now. In his first two books, Dr. Dale Bredesen outlined the revolutionary treatments that are changing what had previously seemed like the inevitable outcome of cognitive decline and dementia. And in these moving narratives, you can hear directly from the first survivors of Alzheimer's themselves--their own amazing stories of hope told in their own words. These first person accounts honestly detail the fear, struggle, and ultimate victory of each patient's journey. They vividly describe what it is like to have Alzheimer's. They also drill down on how each of these patients made the program work for them--the challenges, the workarounds, the encouraging results that are so motivating. Dr. Bredesen includes commentary following each story to help point readers to the tips and tricks that might help them as well. Dr. Bredesen's patients have not just survived; they have thrived to rediscover fulfilling lives, rewarding relationships, and meaningful work. This book will give unprecedented hope to patients and their families.

Keep Sharp

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Publisher : Simon and Schuster
ISBN 13 : 1501166751
Total Pages : 336 pages
Book Rating : 4.5/5 (11 download)

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Book Synopsis Keep Sharp by : Sanjay Gupta

Download or read book Keep Sharp written by Sanjay Gupta and published by Simon and Schuster. This book was released on 2021-01-05 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Keep your brain young, healthy, and sharp with this science-driven guide to protecting your mind from decline by neurosurgeon and CNN chief medical correspondent Dr. Sanjay Gupta. Throughout our life, we look for ways to keep our minds sharp and effortlessly productive. Now, globetrotting neurosurgeon Dr. Sanjay Gupta offers “the book all of us need, young and old” (Walter Isaacson, #1 New York Times bestselling author of The Code Breaker) with insights from top scientists all over the world, whose cutting-edge research can help you heighten and protect brain function and maintain cognitive health at any age. Keep Sharp debunks common myths about aging and mental decline, explores whether there’s a “best” diet or exercise regimen for the brain, and explains whether it’s healthier to play video games that test memory and processing speed, or to engage in more social interaction. Discover what we can learn from “super-brained” people who are in their eighties and nineties with no signs of slowing down—and whether there are truly any benefits to drugs, supplements, and vitamins. Dr. Gupta also addresses brain disease, particularly Alzheimer’s, answers all your questions about the signs and symptoms, and shows how to ward against it and stay healthy while caring for a partner in cognitive decline. He likewise provides you with a personalized twelve-week program featuring practical strategies to strengthen your brain every day. Keep Sharp is the “must-read owner’s manual” (Arianna Huffington) you’ll need to keep your brain young and healthy regardless of your age!

The Alzheimer's Solution

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Publisher : HarperCollins
ISBN 13 : 0062666495
Total Pages : 218 pages
Book Rating : 4.0/5 (626 download)

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Book Synopsis The Alzheimer's Solution by : Dean Sherzai

Download or read book The Alzheimer's Solution written by Dean Sherzai and published by HarperCollins. This book was released on 2017-09-12 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: A revolutionary, proven program for reversing the symptoms of Alzheimer's disease and cognitive decline from award winning neurologists and codirectors of the Brain Health and Alzheimer's Prevention Program at Loma Linda University Medical Center Over 47 million people are currently living with Alzheimer’s disease worldwide. While all other major diseases are in decline, deaths from Alzheimer’s have increased radically. What you or your loved ones don’t yet know is that 90 percent of Alzheimer’s cases can be prevented. Based on the largest clinical and observational study to date, neurologists and codirectors of the Brain Health and Alzheimer’s Prevention Program at Loma Linda University Medical Center, Drs. Dean and Ayesha Sherzai, offer in The Alzheimer’s Solution the first comprehensive program for preventing Alzheimer’s disease and improving cognitive function. Alzheimer’s disease isn’t a genetic inevitability, and a diagnosis does not need to come with a death sentence. Ninety percent of grandparents, parents, husbands, and wives can be spared. Ninety percent of us can avoid ever getting Alzheimer’s, and for the 10 percent with strong genetic risk for cognitive decline, the disease can be delayed by ten to fifteen years. This isn’t an estimate or wishful thinking; it’s a percentage based on rigorous science and the remarkable results the Sherzais have seen firsthand in their clinic. This much-needed revolutionary book reveals how the brain is a living universe, directly influenced by nutrition, exercise, stress, sleep, and engagement. In other words: what you feed it, how you treat it, when you challenge it, and the ways in which you allow it to rest. These factors are the pillars of the groundbreaking program you’ll find in these pages, which features a personalized assessment for evaluating risk, a five-part program for prevention and symptom-reversal, and day-by-day guides for optimizing cognitive function. You can prevent Alzheimer’s disease from affecting you, your family, friends, and loved ones. Even with a diagnosis, you can reverse cognitive decline and add vibrant years to your life. The future of your brain is finally within your control.

Jan's Story

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Author :
Publisher : Behler Publications
ISBN 13 : 1933016442
Total Pages : 226 pages
Book Rating : 4.9/5 (33 download)

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Book Synopsis Jan's Story by : Barry Rex Petersen

Download or read book Jan's Story written by Barry Rex Petersen and published by Behler Publications. This book was released on 2010 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: CBS News correspondent Barry Petersen tells the tender story of his wife's battle with Early Onset Alzheimer's.

Goodbye, Vitamin

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Publisher : Henry Holt and Company
ISBN 13 : 1250109159
Total Pages : 208 pages
Book Rating : 4.2/5 (51 download)

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Book Synopsis Goodbye, Vitamin by : Rachel Khong

Download or read book Goodbye, Vitamin written by Rachel Khong and published by Henry Holt and Company. This book was released on 2017-07-11 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: Winner of the California Book Award for First Fiction Los Angeles Times Book Prize Finalist for First Fiction "A quietly brilliant disquisition . . . told in prose that is so startling in its spare beauty that I found myself thinking about Khong's turns of phrase for days after I finished reading."—Doree Shafrir, The New York Times Book Review Her life at a crossroads, a young woman goes home again in this funny and inescapably moving debut from a wonderfully original new literary voice. Freshly disengaged from her fiancé and feeling that life has not turned out quite the way she planned, thirty-year-old Ruth quits her job, leaves town and arrives at her parents’ home to find that situation more complicated than she'd realized. Her father, a prominent history professor, is losing his memory and is only erratically lucid. Ruth’s mother, meanwhile, is lucidly erratic. But as Ruth's father’s condition intensifies, the comedy in her situation takes hold, gently transforming her all her grief. Told in captivating glimpses and drawn from a deep well of insight, humor, and unexpected tenderness, Goodbye, Vitamin pilots through the loss, love, and absurdity of finding one’s footing in this life.

The End of Alzheimer's Programme

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Author :
Publisher : Random House
ISBN 13 : 1473564166
Total Pages : 226 pages
Book Rating : 4.4/5 (735 download)

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Book Synopsis The End of Alzheimer's Programme by : Dr Dale Bredesen

Download or read book The End of Alzheimer's Programme written by Dr Dale Bredesen and published by Random House. This book was released on 2020-08-20 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: The scientifically-proven practical plan to help reverse Alzheimer’s and prevent cognitive decline from the international bestselling author of The End of Alzheimer's. Following his ground-breaking book that transformed how we think about Alzheimer's and its treatment, world-renowned neurology expert Dale Bredesen provides an unprecedented hands-on guide to achieving complete brain health. In The End of Alzheimer's Programme, he lays out step-by-step his highly sought after, scientifically-proven method that you can follow with a healthcare professional to stop Alzheimer's in its tracks. Alzheimer’s Disease is a protective response to an array of factors that directly affect the brain, such as inflammation, genetic inheritance, nutrients and hormones. In this book, Bredesen will show you which of these factors you need to address to enhance your cognitive abilities by laying out a personalised lifestyle plan. Covering sleep, exercise, diet, brain training and more, Bredesen will show you how to retain, regain and maximise cognitive function for any ability and for any age with extraordinary results. Based on cutting-edge research and full of inspiring success stories from Bredesen’s patients, this book is a must-read for anyone looking to enhance their brainpower and is a vital guide for carers and healthcare professionals.

The Problem of Alzheimer's

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Author :
Publisher : St. Martin's Press
ISBN 13 : 1250218748
Total Pages : 269 pages
Book Rating : 4.2/5 (52 download)

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Book Synopsis The Problem of Alzheimer's by : Jason Karlawish

Download or read book The Problem of Alzheimer's written by Jason Karlawish and published by St. Martin's Press. This book was released on 2021-02-23 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: A definitive and compelling book on one of today's most prevalent illnesses. In 2020, an estimated 5.8 million Americans had Alzheimer’s, and more than half a million died because of the disease and its devastating complications. 16 million caregivers are responsible for paying as much as half of the $226 billion annual costs of their care. As more people live beyond their seventies and eighties, the number of patients will rise to an estimated 13.8 million by 2050. Part case studies, part meditation on the past, present and future of the disease, The Problem of Alzheimer's traces Alzheimer’s from its beginnings to its recognition as a crisis. While it is an unambiguous account of decades of missed opportunities and our health care systems’ failures to take action, it tells the story of the biomedical breakthroughs that may allow Alzheimer’s to finally be prevented and treated by medicine and also presents an argument for how we can live with dementia: the ways patients can reclaim their autonomy and redefine their sense of self, how families can support their loved ones, and the innovative reforms we can make as a society that would give caregivers and patients better quality of life. Rich in science, history, and characters, The Problem of Alzheimer's takes us inside laboratories, patients' homes, caregivers’ support groups, progressive care communities, and Jason Karlawish's own practice at the Penn Memory Center.

Biomarkers in Alzheimer's Disease

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Author :
Publisher : Academic Press
ISBN 13 : 0128051477
Total Pages : 278 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Biomarkers in Alzheimer's Disease by : Tapan Khan

Download or read book Biomarkers in Alzheimer's Disease written by Tapan Khan and published by Academic Press. This book was released on 2016-08-02 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomarkers in Alzheimer's Disease provides a comprehensive overview of all modalities of Alzheimer's disease biomarkers, including neuroimaging, cerebrospinal fluid, genomic, and peripheral systems. Each chapter integrates molecular/cellular abnormality due to Alzheimer's disease and technological advancement of biomarkers techniques. The book is ideal for clinical neuroscience and molecular/cellular neuroscience researchers, psychiatrists, and allied healthcare practitioners involved in the diagnosis and management of patients with cognitive impairment and Alzheimer's disease, and for differential diagnosis of Alzheimer's disease with other non-Alzheimer's dementia. - Presents a comprehensive overview detailing all modalities of Alzheimer's disease biomarkers - Written for neuroscience researchers and clinicians studying or treating patients with Alzheimer's Disease - Integrates, in each chapter, the molecular/cellular abnormality due to Alzheimer's disease and the technological advancement of biomarkers techniques

In Love: A Memoir of Love and Loss

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Publisher : Granta Books
ISBN 13 : 1783788003
Total Pages : 183 pages
Book Rating : 4.7/5 (837 download)

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Book Synopsis In Love: A Memoir of Love and Loss by : Amy Bloom

Download or read book In Love: A Memoir of Love and Loss written by Amy Bloom and published by Granta Books. This book was released on 2022-03-10 with total page 183 pages. Available in PDF, EPUB and Kindle. Book excerpt: In January 2020, Amy Bloom travelled with her husband Brian to Switzerland, where he was helped by Dignitas to end his life while Amy sat with him and held his hand. Brian was terminally ill and for the last year of his life Amy had struggled to find a way to support his wish to take control of his death, to not submerge 'into the darkness of an expiring existence'. Written with piercing insight and wit, In Love is Bloom's intimate, authentic and startling account of losing Brian, first slowly to the disease of Alzheimer's, and then on becoming a widow. It charts the anxiety and pain of the process that led them to Dignitas, while never avoiding the complex ethical problems that are raised by assisted death. A poignant love letter to Bloom's husband and a passionate outpouring of grief, In Love reaffirms the power and value of human relationships.

The Inheritance

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Publisher : Simon and Schuster
ISBN 13 : 1451697333
Total Pages : 407 pages
Book Rating : 4.4/5 (516 download)

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Book Synopsis The Inheritance by : Niki Kapsambelis

Download or read book The Inheritance written by Niki Kapsambelis and published by Simon and Schuster. This book was released on 2017-03-07 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt: This gripping story of the doctors at the forefront of Alzheimer’s research and the courageous North Dakota family whose rare genetic code is helping to understand our most feared diseases is “excellent, accessible...A science text that reads like a mystery and treats its subjects with humanity and sympathy” (Library Journal, starred review). Every sixty-nine seconds, someone is diagnosed with Alzheimer’s disease. Of the top ten killers, it is the only disease for which there is no cure or treatment. For most people, there is nothing that they can do to fight back. But one family is doing all they can. The DeMoe family has the most devastating form of the disease that there is: early onset Alzheimer’s, an inherited genetic mutation that causes the disease in one hundred percent of cases, and has a fifty percent chance of being passed onto the next generation. Of the six DeMoe children whose father had it, five have inherited the gene; the sixth, daughter Karla, has inherited responsibility for all of them. But rather than give up in the face of such news, the DeMoes have agreed to spend their precious, abbreviated years as part of a worldwide study that could utterly change the landscape of Alzheimer’s research and offers the brightest hope for future treatments—and possibly a cure. Drawing from several years of in-depth research with this charming and upbeat family, journalist Niki Kapsambelis tells the story of Alzheimer’s through the humanizing lens of these ordinary people made extraordinary by both their terrible circumstances and their bravery. “A compelling narrative…and an educational and emotional chronicle” (Kirkus Reviews, starred review), their tale is intertwined with the dramatic narrative history of the disease, the cutting-edge research that brings us ever closer to a possible cure, and the accounts of the extraordinary doctors spearheading these groundbreaking studies. From the oil fields of North Dakota to the jungles of Colombia, this inspiring race against time redefines courage in the face of this most pervasive and mysterious disease.