Bottle of Lies

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Author :
Publisher : HarperCollins
ISBN 13 : 0063054108
Total Pages : 512 pages
Book Rating : 4.0/5 (63 download)

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Book Synopsis Bottle of Lies by : Katherine Eban

Download or read book Bottle of Lies written by Katherine Eban and published by HarperCollins. This book was released on 2020-06-23 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: A NEW YORK TIMES BESTSELLER New York Times 100 Notable Books of 2019 New York Public Library Best Books of 2019 Kirkus Reviews Best Health and Science Books of 2019 Science Friday Best Books of 2019 New postscript by the author From an award-winning journalist, an explosive narrative investigation of the generic drug boom that reveals fraud and life-threatening dangers on a global scale—The Jungle for pharmaceuticals Many have hailed the widespread use of generic drugs as one of the most important public-health developments of the twenty-first century. Today, almost 90 percent of our pharmaceutical market is comprised of generics, the majority of which are manufactured overseas. We have been reassured by our doctors, our pharmacists and our regulators that generic drugs are identical to their brand-name counterparts, just less expensive. But is this really true? Katherine Eban’s Bottle of Lies exposes the deceit behind generic-drug manufacturing—and the attendant risks for global health. Drawing on exclusive accounts from whistleblowers and regulators, as well as thousands of pages of confidential FDA documents, Eban reveals an industry where fraud is rampant, companies routinely falsify data, and executives circumvent almost every principle of safe manufacturing to minimize cost and maximize profit, confident in their ability to fool inspectors. Meanwhile, patients unwittingly consume medicine with unpredictable and dangerous effects. The story of generic drugs is truly global. It connects middle America to China, India, sub-Saharan Africa and Brazil, and represents the ultimate litmus test of globalization: what are the risks of moving drug manufacturing offshore, and are they worth the savings? A decade-long investigation with international sweep, high-stakes brinkmanship and big money at its core, Bottle of Lies reveals how the world’s greatest public-health innovation has become one of its most astonishing swindles.

Bottles of Lies

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Author :
Publisher :
ISBN 13 : 9789353450441
Total Pages : 0 pages
Book Rating : 4.4/5 (54 download)

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Book Synopsis Bottles of Lies by : Katherine Eban

Download or read book Bottles of Lies written by Katherine Eban and published by . This book was released on 2019-07 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Many have hailed the widespread use of generic drugs as one of the most important public-health developments of the twenty-first century. Today, almost 90 percent of our pharmaceutical market is comprised of generics, the majority of which are manufactured overseas. We have been reassured by our doctors, our pharmacists and our regulators that generic drugs are identical to their brand-name counterparts, just less expensive. But is this really true? Katherine Eban's Bottle of Lies exposes the deceit behind generic-drug manufacturing--and the attendant risks for global health. Drawing on exclusive accounts from whistleblowers and regulators, as well as thousands of pages of confidential FDA documents, Eban reveals an industry where fraud is rampant, companies routinely falsify data, and executives circumvent almost every principle of safe manufacturing to minimize cost and maximize profit, confident in their ability to fool inspectors. Meanwhile, patients unwittingly consume medicine with unpredictable and dangerous effects. The story of generic drugs is truly global. It connects middle America to China, India, sub-Saharan Africa and Brazil, and represents the ultimate litmus test of globalization: what are the risks of moving drug manufacturing offshore, and are they worth the savings?"--Dust jacket.

Dangerous Doses

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Publisher : Houghton Mifflin Harcourt
ISBN 13 : 9780156030854
Total Pages : 479 pages
Book Rating : 4.0/5 (38 download)

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Book Synopsis Dangerous Doses by : Katherine Eban

Download or read book Dangerous Doses written by Katherine Eban and published by Houghton Mifflin Harcourt. This book was released on 2006-04-18 with total page 479 pages. Available in PDF, EPUB and Kindle. Book excerpt: An exploration of drug counterfeiting activities in America traces a drug theft investigation in Florida with ties to a national network of drug polluters and the government, exposing how political interests may be compromising the integrity of the nation's medical distribution system. Reprint. 30,000 first printing.

Pharma

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Publisher : Simon and Schuster
ISBN 13 : 1501152041
Total Pages : 816 pages
Book Rating : 4.5/5 (11 download)

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Book Synopsis Pharma by : Gerald Posner

Download or read book Pharma written by Gerald Posner and published by Simon and Schuster. This book was released on 2020-03-10 with total page 816 pages. Available in PDF, EPUB and Kindle. Book excerpt: Award-winning journalist and New York Times bestselling author Gerald Posner reveals the heroes and villains of the trillion-dollar-a-year pharmaceutical industry and delivers “a withering and encyclopedic indictment of a drug industry that often seems to prioritize profits over patients (The New York Times Book Review). Pharmaceutical breakthroughs such as anti­biotics and vaccines rank among some of the greatest advancements in human history. Yet exorbitant prices for life-saving drugs, safety recalls affecting tens of millions of Americans, and soaring rates of addiction and overdose on pre­scription opioids have caused many to lose faith in drug companies. Now, Americans are demanding a national reckoning with a monolithic industry. “Gerald’s dogged reporting, sets Pharma apart from all books on this subject” (The Washington Standard) as we are introduced to brilliant scientists, incorruptible government regulators, and brave whistleblowers facing off against company exec­utives often blinded by greed. A business that profits from treating ills can create far deadlier problems than it cures. Addictive products are part of the industry’s DNA, from the days when corner drugstores sold morphine, heroin, and cocaine, to the past two decades of dangerously overprescribed opioids. Pharma also uncovers the real story of the Sacklers, the family that became one of America’s wealthiest from the success of OxyContin, their blockbuster narcotic painkiller at the center of the opioid crisis. Relying on thousands of pages of government and corporate archives, dozens of hours of interviews with insiders, and previously classified FBI files, Posner exposes the secrets of the Sacklers’ rise to power—revelations that have long been buried under a byzantine web of interlocking companies with ever-changing names and hidden owners. The unexpected twists and turns of the Sackler family saga are told against the startling chronicle of a powerful industry that sits at the intersection of public health and profits. “Explosively, even addictively, readable” (Booklist, starred review), Pharma reveals how and why American drug com­panies have put earnings ahead of patients.

Drugged

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Author :
Publisher : Oxford University Press, USA
ISBN 13 : 0199957975
Total Pages : 375 pages
Book Rating : 4.1/5 (999 download)

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Book Synopsis Drugged by : Richard J. Miller

Download or read book Drugged written by Richard J. Miller and published by Oxford University Press, USA. This book was released on 2014 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: Miller takes readers on an eye-opening tour of psychotropic drugs, describing the various kinds, how they were discovered and developed, and how they have played multiple roles in virtually every culture.

Sickening

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Publisher : HarperCollins
ISBN 13 : 1328956989
Total Pages : 336 pages
Book Rating : 4.3/5 (289 download)

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Book Synopsis Sickening by : John Abramson

Download or read book Sickening written by John Abramson and published by HarperCollins. This book was released on 2022-02-08 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: The inside story of how Big Pharma’s relentless pursuit of ever-higher profits corrupts medical knowledge—misleading doctors, misdirecting American health care, and harming our health. The United States spends an excess $1.5 trillion annually on health care compared to other wealthy countries—yet the amount of time that Americans live in good health ranks a lowly 68th in the world. At the heart of the problem is Big Pharma, which funds most clinical trials and therefore controls the research agenda, withholds the real data from those trials as corporate secrets, and shapes most of the information relied upon by health care professionals. In this no-holds-barred exposé, Dr. John Abramson—one of the foremost experts on the drug industry’s deceptive tactics—combines patient stories with what he learned during many years of serving as an expert in national drug litigation to reveal the tangled web of financial interests at the heart of the dysfunction in our health-care system. For example, one of pharma’s best-kept secrets is that the peer reviewers charged with ensuring the accuracy and completeness of the clinical trial reports published in medical journals do not even have access to complete data and must rely on manufacturer-influenced summaries. Likewise for the experts who write the clinical practice guidelines that define our standards of care. The result of years of research and privileged access to the inner workings of the U.S. medical-industrial complex, Sickening shines a light on the dark underbelly of American health care—and presents a path toward genuine reform.

Kill Shot

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Publisher : Penguin
ISBN 13 : 0593421353
Total Pages : 273 pages
Book Rating : 4.5/5 (934 download)

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Book Synopsis Kill Shot by : Jason Dearen

Download or read book Kill Shot written by Jason Dearen and published by Penguin. This book was released on 2022-02-22 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in paperback. An award-winning investigative journalist's horrifying true crime story of America's deadliest drug contamination outbreak and the greed and deception that fueled it. Two pharmacists sit in a Boston courtroom accused of murder. The weapon: the fungus Exserohilum rostratum. The death count: 100 and rising. Kill Shot is the story of their hubris and fraud, discovered by a team of medical detectives who raced against the clock to hunt the killers and the fungal meningitis they'd unleashed. "Bloodthirsty" is how doctors described the fungal microbe that contaminated thousands of drug vials produced by the New England Compounding Center (NECC). Though NECC chief Barry Cadden called his company the "Ferrari of Compounders," it was a slapdash operation of unqualified staff, mold-ridden lab surfaces, and hastily made medications that were injected into approximately 14,000 people. Once inside some of its human hosts, the fungus traveled through the tough tissue around the spine and wormed upward to the "deep brain," our control center for balance, breath, and the vital motor functions of life. Now, investigative journalist Jason Dearen turns a spotlight on this tragedy--the victims, the heroes, and the perpetrators--and the legal loopholes that allowed it to occur. Kill Shot forces a powerful but unchecked industry out of the shadows.

Ten Drugs

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Author :
Publisher : Abrams
ISBN 13 : 1683355318
Total Pages : 342 pages
Book Rating : 4.6/5 (833 download)

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Book Synopsis Ten Drugs by : Thomas Hager

Download or read book Ten Drugs written by Thomas Hager and published by Abrams. This book was released on 2019-03-05 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: “The stories are skillfully told and entirely entertaining . . . An expert, mostly feel-good book about modern medicine” from the award-winning author (Kirkus Reviews, starred review). Behind every landmark drug is a story. It could be an oddball researcher’s genius insight, a catalyzing moment in geopolitical history, a new breakthrough technology, or an unexpected but welcome side effect discovered during clinical trials. Piece together these stories, as Thomas Hager does in this remarkable, century-spanning history, and you can trace the evolution of our culture and the practice of medicine. Beginning with opium, the “joy plant,” which has been used for 10,000 years, Hager tells a captivating story of medicine. His subjects include the largely forgotten female pioneer who introduced smallpox inoculation to Britain, the infamous knockout drops, the first antibiotic, which saved countless lives, the first antipsychotic, which helped empty public mental hospitals, Viagra, statins, and the new frontier of monoclonal antibodies. This is a deep, wide-ranging, and wildly entertaining book. “[An] absorbing new book.” —The New York Times Book Review “[A] well-written and engaging chronicle.” —The Wall Street Journal “Lucidly informative and compulsively readable.” —Publishers Weekly “Entertaining [and] insightful.” —Booklist “Well-written, well-researched and fascinating to read Ten Drugs provides an insightful look at how drugs have shaped modern medical practices. Towards the end of the book Hager writes that he ‘came away surprised by some of the things he had learned.’ I had the very same reaction.” —Penny Le Couteur, coauthor of Napoleon’s Buttons: How 17 Molecules Changed History

Overdosed America

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Publisher : Harper Collins
ISBN 13 : 0060568534
Total Pages : 362 pages
Book Rating : 4.0/5 (65 download)

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Book Synopsis Overdosed America by : John Abramson

Download or read book Overdosed America written by John Abramson and published by Harper Collins. This book was released on 2005-06-14 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using the examples of Vioxx, Celebrex, cholesterol-lowering statin drugs, and anti-depressants, Overdo$ed America shows that at the heart of the current crisis in American medicine lies the commercialization of medical knowledge itself. Drawing on his background in statistics, epidemiology, and health policy, John Abramson, M.D., an award-winning family doctor on the clinical faculty at Harvard Medical School, reveals the ways in which the drug companies have misrepresented statistical evidence, misled doctors, and compromised our health. The good news is that the best scientific evidence shows that reclaiming responsibility for your own health is often far more effective than taking the latest blockbuster drug. You -- and your doctor -- will be stunned by this unflinching exposé of American medicine.

Sick Money

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Publisher : Canongate Books
ISBN 13 : 1838850279
Total Pages : 553 pages
Book Rating : 4.8/5 (388 download)

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Book Synopsis Sick Money by : Billy Kenber

Download or read book Sick Money written by Billy Kenber and published by Canongate Books. This book was released on 2021-10-07 with total page 553 pages. Available in PDF, EPUB and Kindle. Book excerpt: THE PHARMACEUTICAL INDUSTRY IS BROKEN From the American hedge fund manager who drastically hiked the price of an AIDS pill to the children’s cancer drugs left intentionally to expire in a Spanish warehouse, the signs of this dysfunction are all around. A system built to drive innovation and improve patient care has been distorted to maximise profits. In Sick Money, the investigative journalist who exposed a billion-pound British price-hiking scandal goes inside the global battle over high drug prices. From secret deals to patients forced to turn to the black market, Billy Kenber reveals how medicines have become nothing more than financial assets. He offers a diagnosis of an industry in crisis - and a prescription for how it could be fixed.

China Rx

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Publisher : Prometheus Books
ISBN 13 : 1633883817
Total Pages : 306 pages
Book Rating : 4.6/5 (338 download)

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Book Synopsis China Rx by : Rosemary Gibson

Download or read book China Rx written by Rosemary Gibson and published by Prometheus Books. This book was released on 2018 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Millions of Americans are taking prescription drugs made in China and don't know it-- and pharmaceutical companies are not eager to tell them. This probing book examines the implications for the quality and availability of vital medicines for consumers. Several decades ago, penicillin, vitamin C, and many other prescription and over-the-counter products were manufactured in the United States. But with the rise of globalization, antibiotics, antidepressants, birth control pills, blood pressure medicines, cancer drugs, among many others are made in China and sold in the United States. China's biggest impact on the US drug supply is making essential ingredients for thousands of medicines found in American homes and used in hospital intensive care units and operating rooms. The authors convincingly argue that there are at least two major problems with this scenario. First, it is inherently risky for the United States to become dependent on any one country as a source for vital medicines, especially given the uncertainties of geopolitics. For example, if an altercation in the South China Sea causes military personnel to be wounded, doctors may rely upon medicines with essential ingredients made by the adversary. Second, lapses in safety standards and quality control in Chinese manufacturing are a risk. Citing the concerns of FDA officials and insiders within the pharmaceutical industry, the authors document incidents of illness and death caused by contaminated medications that prompted reform. This is a disturbing, well-researched book and a wake-up call for improving the current system of drug supply and manufacturing.

The Right Price

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Publisher : Oxford University Press
ISBN 13 : 0197512887
Total Pages : 273 pages
Book Rating : 4.1/5 (975 download)

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Book Synopsis The Right Price by : Peter J. Neumann

Download or read book The Right Price written by Peter J. Neumann and published by Oxford University Press. This book was released on 2021 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: The prescription drug market -- Proposed solutions for rising drug prices -- Measuring the value of prescription drugs -- Measuring drug value : whose job is it anyway? -- Institute for Clinical and Economic Review (ICER) -- Other US value assessment frameworks -- Do drugs for special populations warrant higher prices? -- Improving value measurement -- Aligning prices with value -- The path forward.

Healing the Pharmacy of the World

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Publisher : Notion Press
ISBN 13 : 1639403566
Total Pages : 251 pages
Book Rating : 4.6/5 (394 download)

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Book Synopsis Healing the Pharmacy of the World by : K.L. Sharma

Download or read book Healing the Pharmacy of the World written by K.L. Sharma and published by Notion Press. This book was released on 2021-08-30 with total page 251 pages. Available in PDF, EPUB and Kindle. Book excerpt: Indian pharmaceutical industry, it is argued, has democratized the availability, accessibility and affordability of medicines. Everyone, rich or poor, can now get them at a fraction of the cost of branded drugs. However, the allegations about their suspect quality, if true, pose questions of life-and-death for the unsuspecting consumers. Is it the messiah supplying the low-cost quality medicines across the globe or is it the precursor for the ultimate indigence of the unsuspecting millions consuming poor-quality generic medicines? In the absence of any evidence, it remains an inexplicable enigma. This book by a public policy practitioner of four decades who steered drug regulation in the Government of India unravels the truth.

The Billion-Dollar Molecule

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Publisher : Simon and Schuster
ISBN 13 : 143912681X
Total Pages : 480 pages
Book Rating : 4.4/5 (391 download)

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Book Synopsis The Billion-Dollar Molecule by : Barry Werth

Download or read book The Billion-Dollar Molecule written by Barry Werth and published by Simon and Schuster. This book was released on 2013-08-20 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: Join journalist Barry Werth as he pulls back the curtain on Vertex, a start-up pharmaceutical company, and witness firsthand the intense drama being played out in the pioneering and hugely profitable field of drug research. Founded by Joshua Boger, a dynamic Harvard- and Merck-trained scientific whiz kid, Vertex is dedicated to designing—atom by atom—both a new life-saving immunosuppressant drug, and a drug to combat the virus that causes AIDS. You will be hooked from start to finish, as you go from the labs, where obsessive, fiercely competitive scientists struggle for a breakthrough, to Wall Street, where the wheeling and dealing takes on a life of its own, as Boger courts investors and finally decides to take Vertex public. Here is a fascinating no-holds-barred account of the business of science, which includes an updated epilogue about the most recent developments in the quest for a drug to cure AIDS.

The Drug Hunters

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Publisher : Simon and Schuster
ISBN 13 : 1628727195
Total Pages : 328 pages
Book Rating : 4.6/5 (287 download)

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Book Synopsis The Drug Hunters by : Donald R. Kirsch

Download or read book The Drug Hunters written by Donald R. Kirsch and published by Simon and Schuster. This book was released on 2016-12-13 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: The surprising, behind-the-scenes story of how our medicines are discovered, told by a veteran drug hunter. The search to find medicines is as old as disease, which is to say as old as the human race. Through serendipity— by chewing, brewing, and snorting—some Neolithic souls discovered opium, alcohol, snakeroot, juniper, frankincense, and other helpful substances. Ötzi the Iceman, the five-thousand-year-old hunter frozen in the Italian Alps, was found to have whipworms in his intestines and Bronze-age medicine, a worm-killing birch fungus, knotted to his leggings. Nowadays, Big Pharma conglomerates spend billions of dollars on state-of the art laboratories staffed by PhDs to discover blockbuster drugs. Yet, despite our best efforts to engineer cures, luck, trial-and-error, risk, and ingenuity are still fundamental to medical discovery. The Drug Hunters is a colorful, fact-filled narrative history of the search for new medicines from our Neolithic forebears to the professionals of today, and from quinine and aspirin to Viagra, Prozac, and Lipitor. The chapters offer a lively tour of how new drugs are actually found, the discovery strategies, the mistakes, and the rare successes. Dr. Donald R. Kirsch infuses the book with his own expertise and experiences from thirty-five years of drug hunting, whether searching for life-saving molecules in mudflats by Chesapeake Bay or as a chief science officer and research group leader at major pharmaceutical companies.

No Stopping Us Now

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Publisher : Little, Brown
ISBN 13 : 0316286494
Total Pages : 432 pages
Book Rating : 4.3/5 (162 download)

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Book Synopsis No Stopping Us Now by : Gail Collins

Download or read book No Stopping Us Now written by Gail Collins and published by Little, Brown. This book was released on 2019-10-15 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: The beloved New York Times columnist "inspires women to embrace aging and look at it with a new sense of hope" in this lively, fascinating, eye-opening look at women and aging in America (Parade Magazine). "You're not getting older, you're getting better," or so promised the famous 1970's ad -- for women's hair dye. Americans have always had a complicated relationship with aging: embrace it, deny it, defer it -- and women have been on the front lines of the battle, willingly or not. In her lively social history of American women and aging, acclaimed New York Times columnist Gail Collins illustrates the ways in which age is an arbitrary concept that has swung back and forth over the centuries. From Plymouth Rock (when a woman was considered marriageable if "civil and under fifty years of age"), to a few generations later, when they were quietly retired to elderdom once they had passed the optimum age for reproduction, to recent decades when freedom from striving in the workplace and caretaking at home is often celebrated, to the first female nominee for president, American attitudes towards age have been a moving target. Gail Collins gives women reason to expect the best of their golden years.

The Rodchenkov Affair

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Author :
Publisher : Random House
ISBN 13 : 0753553341
Total Pages : 242 pages
Book Rating : 4.7/5 (535 download)

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Book Synopsis The Rodchenkov Affair by : Grigory Rodchenkov

Download or read book The Rodchenkov Affair written by Grigory Rodchenkov and published by Random House. This book was released on 2020-07-30 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: ***Winner of the William Hill Sports Book of the Year, 2020 - the inside story of the Russian doping programme by the man behind it all*** One of the Financial Times's 'Fifty people who shaped the decade' 'The biggest sports scandal the world has ever seen' In 2015, Russia's Anti-Doping Centre was suspended by the World Anti-Doping Agency (WADA) following revelations of an elaborate state-sponsored doping programme at the 2014 Sochi Winter Olympics. Involving a nearly undetectable steroid delivery system known as 'Duchesse cocktail', tampering and switching of urine samples, and a complex state-sanctioned cover-up, the programme was masterminded by Grigory Rodchenkov. The Rodchenkov Affair tells the full, unadulterated story that was first glimpsed in Bryan Fogel's award-winning documentary and still continues to captivate and shock the world. Charting the author's childhood growing up under the Iron Curtain, his first encounter with doping as a 22-year-old student athlete at Moscow State University, and his subsequent career working for the Soviet Olympic Committee, this breathtakingly candid journey reveals a rigged system of flawed individuals, brazen deceit and impossible moral choices.