Summary Of Jennifer A Doudna Samuel H Sternbergs A Crack In Creation

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A Crack In Creation

Author : Jennifer A. Doudna
Publisher : HarperCollins
ISBN 13 : 0544716965
Total Pages : 307 pages
Book Rating : 4.5/5 (447 download)

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Book Synopsis A Crack In Creation by : Jennifer A. Doudna

Download or read book A Crack In Creation written by Jennifer A. Doudna and published by HarperCollins. This book was released on 2017-06-13 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: BY THE WINNER OF THE 2020 NOBEL PRIZE IN CHEMISTRY | Finalist for the Los Angeles Times Book Prize “A powerful mix of science and ethics . . . This book is required reading for every concerned citizen—the material it covers should be discussed in schools, colleges, and universities throughout the country.”— New York Review of Books Not since the atomic bomb has a technology so alarmed its inventors that they warned the world about its use. That is, until 2015, when biologist Jennifer Doudna called for a worldwide moratorium on the use of the gene-editing tool CRISPR—a revolutionary new technology that she helped create—to make heritable changes in human embryos. The cheapest, simplest, most effective way of manipulating DNA ever known, CRISPR may well give us the cure to HIV, genetic diseases, and some cancers. Yet even the tiniest changes to DNA could have myriad, unforeseeable consequences, to say nothing of the ethical and societal repercussions of intentionally mutating embryos to create “better” humans. Writing with fellow researcher Sam Sternberg, Doudna—who has since won the Nobel Prize for her CRISPR research—shares the thrilling story of her discovery and describes the enormous responsibility that comes with the power to rewrite the code of life. “The future is in our hands as never before, and this book explains the stakes like no other.” — George Lucas “An invaluable account . . . We owe Doudna several times over.” — Guardian

A Crack in Creation

Author : Jennifer Doudna
Publisher : Vintage
ISBN 13 : 9781784702762
Total Pages : 304 pages
Book Rating : 4.7/5 (27 download)

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Book Synopsis A Crack in Creation by : Jennifer Doudna

Download or read book A Crack in Creation written by Jennifer Doudna and published by Vintage. This book was released on 2018-06-14 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: A handful of discoveries have changed the course of human history. This book is about the most recent and potentially the most powerful and dangerous of them all. It is an invention that allows us to rewrite the genetic code that shapes and controls all living beings with astonishing accuracy and ease. Thanks to it, the dreams of genetic manipulation have become a stark reality: the power to cure disease and alleviate suffering, to create new sources of food and energy, as well as to re-design any species, including humans, for our own ends. Jennifer Doudna is the co-inventor of this technology - known as CRISPR - and a scientist of worldwide renown. Writing with fellow researcher Samuel Sternberg, here she provides the definitive account of her discovery, explaining how this wondrous invention works and what it is capable of. She also asks us to consider what our new-found power means: how do we enjoy its unprecedented benefits while avoiding its equally unprecedented dangers? The future of humankind - and of all life on Earth - is at stake. This book is an essential guide to the path that now lies ahead.

Hacking Darwin

Author : Jamie Metzl
Publisher : Sourcebooks, Inc.
ISBN 13 : 1492670103
Total Pages : 251 pages
Book Rating : 4.4/5 (926 download)

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Book Synopsis Hacking Darwin by : Jamie Metzl

Download or read book Hacking Darwin written by Jamie Metzl and published by Sourcebooks, Inc.. This book was released on 2019-04-23 with total page 251 pages. Available in PDF, EPUB and Kindle. Book excerpt: "A gifted and thoughtful writer, Metzl brings us to the frontiers of biology and technology, and reveals a world full of promise and peril." — Siddhartha Mukherjee MD, New York Times bestselling author of The Emperor of All Maladies and The Gene A groundbreaking exploration of genetic engineering and its impact on the future of our species from leading geopolitical expert and technology futurist, Jamie Metzl. At the dawn of the genetics revolution, our DNA is becoming as readable, writable, and hackable as our information technology. But as humanity starts retooling our own genetic code, the choices we make today will be the difference between realizing breathtaking advances in human well-being and descending into a dangerous and potentially deadly genetic arms race. Enter the laboratories where scientists are turning science fiction into reality. In this captivating and thought-provoking nonfiction science book, Jamie Metzl delves into the ethical, scientific, political, and technological dimensions of genetic engineering, and shares how it will shape the course of human evolution. Cutting-edge insights into the field of genetic engineering and its implications for humanity's future Explores the transformative power of genetic technologies and their potential to reshape human life Examines the ethical considerations surrounding genetic engineering and the choices we face as a species Engaging narrative that delves into the scientific breakthroughs and real-world applications of genetic technologies Provides a balanced perspective on the promises and risks associated with genetic engineering Raises thought-provoking questions about the future of reproduction, human health, and our relationship with nature Drawing on his extensive background in genetics, national security, and foreign policy, Metzl paints a vivid picture of a world where advancements in technology empower us to take control of our own evolution, but also cautions against the pitfalls and ethical dilemmas that could arise if not properly managed. Hacking Darwin is a must-read for anyone interested in the intersection of science, technology, and humanity's future.

Editing Humanity

Author : Kevin Davies
Publisher : Simon and Schuster
ISBN 13 : 1643133942
Total Pages : 402 pages
Book Rating : 4.6/5 (431 download)

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Book Synopsis Editing Humanity by : Kevin Davies

Download or read book Editing Humanity written by Kevin Davies and published by Simon and Schuster. This book was released on 2020-10-06 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the world's leading experts on genetics unravels one of the most important breakthroughs in modern science and medicine. IIf our genes are, to a great extent, our destiny, then what would happen if mankind could engineer and alter the very essence of our DNA coding? Millions might be spared the devastating effects of hereditary disease or the challenges of disability, whether it was the pain of sickle-cell anemia to the ravages of Huntington’s disease. But this power to “play God” also raises major ethical questions and poses threats for potential misuse. For decades, these questions have lived exclusively in the realm of science fiction, but as Kevin Davies powerfully reveals in his new book, this is all about to change. Engrossing and page-turning, Editing Humanity takes readers inside the fascinating world of a new gene editing technology called CRISPR, a high-powered genetic toolkit that enables scientists to not only engineer but to edit the DNA of any organism down to the individual building blocks of the genetic code. Davies introduces readers to arguably the most profound scientific breakthrough of our time. He tracks the scientists on the front lines of its research to the patients whose powerful stories bring the narrative movingly to human scale. Though the birth of the “CRISPR babies” in China made international news, there is much more to the story of CRISPR than headlines seemingly ripped from science fiction. In Editing Humanity, Davies sheds light on the implications that this new technology can have on our everyday lives and in the lives of generations to come.

The Code Breaker

Author : Walter Isaacson
Publisher : Simon and Schuster
ISBN 13 : 1982115874
Total Pages : 560 pages
Book Rating : 4.9/5 (821 download)

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Book Synopsis The Code Breaker by : Walter Isaacson

Download or read book The Code Breaker written by Walter Isaacson and published by Simon and Schuster. This book was released on 2021-03-09 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Best Book of 2021 by Bloomberg BusinessWeek, Time, and The Washington Post The bestselling author of Leonardo da Vinci and Steve Jobs returns with a “compelling” (The Washington Post) account of how Nobel Prize winner Jennifer Doudna and her colleagues launched a revolution that will allow us to cure diseases, fend off viruses, and have healthier babies. When Jennifer Doudna was in sixth grade, she came home one day to find that her dad had left a paperback titled The Double Helix on her bed. She put it aside, thinking it was one of those detective tales she loved. When she read it on a rainy Saturday, she discovered she was right, in a way. As she sped through the pages, she became enthralled by the intense drama behind the competition to discover the code of life. Even though her high school counselor told her girls didn’t become scientists, she decided she would. Driven by a passion to understand how nature works and to turn discoveries into inventions, she would help to make what the book’s author, James Watson, told her was the most important biological advance since his codiscovery of the structure of DNA. She and her collaborators turned a curiosity of nature into an invention that will transform the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions. The development of CRISPR and the race to create vaccines for coronavirus will hasten our transition to the next great innovation revolution. The past half-century has been a digital age, based on the microchip, computer, and internet. Now we are entering a life-science revolution. Children who study digital coding will be joined by those who study genetic code. Should we use our new evolution-hacking powers to make us less susceptible to viruses? What a wonderful boon that would be! And what about preventing depression? Hmmm…Should we allow parents, if they can afford it, to enhance the height or muscles or IQ of their kids? After helping to discover CRISPR, Doudna became a leader in wrestling with these moral issues and, with her collaborator Emmanuelle Charpentier, won the Nobel Prize in 2020. Her story is an “enthralling detective story” (Oprah Daily) that involves the most profound wonders of nature, from the origins of life to the future of our species.

The Epigenetics Revolution

Author : Nessa Carey
Publisher : Columbia University Press
ISBN 13 : 0231530714
Total Pages : 353 pages
Book Rating : 4.2/5 (315 download)

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Book Synopsis The Epigenetics Revolution by : Nessa Carey

Download or read book The Epigenetics Revolution written by Nessa Carey and published by Columbia University Press. This book was released on 2012-03-06 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epigenetics can potentially revolutionize our understanding of the structure and behavior of biological life on Earth. It explains why mapping an organism's genetic code is not enough to determine how it develops or acts and shows how nurture combines with nature to engineer biological diversity. Surveying the twenty-year history of the field while also highlighting its latest findings and innovations, this volume provides a readily understandable introduction to the foundations of epigenetics. Nessa Carey, a leading epigenetics researcher, connects the field's arguments to such diverse phenomena as how ants and queen bees control their colonies; why tortoiseshell cats are always female; why some plants need cold weather before they can flower; and how our bodies age and develop disease. Reaching beyond biology, epigenetics now informs work on drug addiction, the long-term effects of famine, and the physical and psychological consequences of childhood trauma. Carey concludes with a discussion of the future directions for this research and its ability to improve human health and well-being.

The Janus Point

Author : Julian Barbour
Publisher : Basic Books
ISBN 13 : 0465095496
Total Pages : 372 pages
Book Rating : 4.4/5 (65 download)

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Book Synopsis The Janus Point by : Julian Barbour

Download or read book The Janus Point written by Julian Barbour and published by Basic Books. This book was released on 2020-12-01 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: In a universe filled by chaos and disorder, one physicist makes the radical argument that the growth of order drives the passage of time -- and shapes the destiny of the universe. Time is among the universe's greatest mysteries. Why, when most laws of physics allow for it to flow forward and backward, does it only go forward? Physicists have long appealed to the second law of thermodynamics, held to predict the increase of disorder in the universe, to explain this. In The Janus Point, physicist Julian Barbour argues that the second law has been misapplied and that the growth of order determines how we experience time. In his view, the big bang becomes the "Janus point," a moment of minimal order from which time could flow, and order increase, in two directions. The Janus Point has remarkable implications: while most physicists predict that the universe will become mired in disorder, Barbour sees the possibility that order -- the stuff of life -- can grow without bound. A major new work of physics, The Janus Point will transform our understanding of the nature of existence.

The Locust Effect

Author : Gary A. Haugen
Publisher : Oxford University Press
ISBN 13 : 0190229268
Total Pages : 371 pages
Book Rating : 4.1/5 (92 download)

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Book Synopsis The Locust Effect by : Gary A. Haugen

Download or read book The Locust Effect written by Gary A. Haugen and published by Oxford University Press. This book was released on 2015-03-17 with total page 371 pages. Available in PDF, EPUB and Kindle. Book excerpt: An urgent call-to-action in support of ending violence against the world's poor reveals how in addition to hunger and disease, impoverish populations have become increasingly subject to assault, forced labor and other physical abuses, outlining recommendations for implementing workable solutions and overcoming corruption.

CRISPR

Author : Yolanda Ridge
Publisher : Annick Press
ISBN 13 : 177321425X
Total Pages : 174 pages
Book Rating : 4.7/5 (732 download)

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Book Synopsis CRISPR by : Yolanda Ridge

Download or read book CRISPR written by Yolanda Ridge and published by Annick Press. This book was released on 2020-09-08 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: We can change the world with gene editing—but should we? CRISPR stands for clustered regularly interspaced short palindromic repeats. If it sounds complicated, it is—but it’s also one of the most powerful ways we can shape the future. And it’s poised to completely upend the way we think about science. Author Yolanda Ridge tackles this topic in a friendly and accessible tone, with two introductory chapters covering the basics of DNA and gene editing before taking readers through the ways that this ground-breaking science could affect them by potentially: • eliminating diseases like malaria and cancer, • improving the stability of our food supply, and • helping to manage conservation efforts for threatened animals and environments. But all of these possible advancements come with risks, the biggest being that the consequences are unknown. Chapters end with “Stop, Go, Yield” sections encouraging readers to consider the pros and cons of using CRISPR. “Cutting Questions” give readers the opportunity to further reflect on the ethics of the science. CRISPR is a game changer. This important book, with detailed scientific illustrations, brings much needed clarity to a topic that will affect readers for generations to come. *A Junior Library Guild Gold Standard Selection

Joy on Demand

Author : Chade-Meng Tan
Publisher : HarperCollins
ISBN 13 : 0062378945
Total Pages : 213 pages
Book Rating : 4.0/5 (623 download)

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Book Synopsis Joy on Demand by : Chade-Meng Tan

Download or read book Joy on Demand written by Chade-Meng Tan and published by HarperCollins. This book was released on 2016-05-31 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt: A long-awaited follow-up to the New York Times bestselling Search Inside Yourself shows us how to cultivate joy within the context of our fast-paced lives and explains why it is critical to creativity, innovation, confidence, and ultimately success in every arena. In Joy on Demand, Chade-Meng Tan shows that you don’t need to meditate for hours, days, months or years to achieve lasting joy—you can actually get consistent access to it in as little as fifteen seconds. Explaining joy and meditation as complementary things that naturally reinforce each other, Meng explains how these two skills form a virtuous cycle, and once put into motion, become a solid practice that can be sustained in daily life. For many years, meditation has been taught and practiced in cultures where almost all meditators practice full-time for years, resulting in training programs optimized for practitioners with lots of free time and not much else to do but develop profound mastery over the mind. Seeing a disconnect between the traditional practice and the modern world, the bestselling author and Google’s “Jolly Good Fellow” has developed a program, through “wise laziness,” to help readers meditate more efficiently and effectively. Meng shares the three pillars of joy (inner peace, insight, and happiness), why joy is the secret is to success, and demonstrates the practical tools anyone can use to cultivate it on demand.

Time, Love , Memory

Author : Jonathan Weiner
Publisher : Vintage
ISBN 13 : 0804153361
Total Pages : 322 pages
Book Rating : 4.8/5 (41 download)

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Book Synopsis Time, Love , Memory by : Jonathan Weiner

Download or read book Time, Love , Memory written by Jonathan Weiner and published by Vintage. This book was released on 2014-05-14 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: The story of Nobel Prize–winning discoveries regarding the molecular mechanisms controlling the body’s circadian rhythm. How much of our fate is decided before we are born? Which of our characteristics is inscribed in our DNA? Weiner brings us into Benzer's Fly Rooms at the California Institute of Technology, where Benzer, and his asssociates are in the process of finding answers, often astonishing ones, to these questions. Part biography, part thrilling scientific detective story, Time, Love, Memory forcefully demonstrates how Benzer's studies are changing our world view--and even our lives. Jonathan Weiner, winner of the Pulitzer Prize for The Beak of the Finch, brings his brilliant reporting skills to the story of Seymour Benzer, the Brooklyn-born maverick scientist whose study of genetics and experiments with fruit fly genes has helped revolutionize or knowledge of the connections between DNA and behavior both animal and human.

Genentech

Author : Sally Smith Hughes
Publisher : University of Chicago Press
ISBN 13 : 0226359204
Total Pages : 231 pages
Book Rating : 4.2/5 (263 download)

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Book Synopsis Genentech by : Sally Smith Hughes

Download or read book Genentech written by Sally Smith Hughes and published by University of Chicago Press. This book was released on 2011-09-21 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the fall of 1980, Genentech, Inc., a little-known California genetic engineering company, became the overnight darling of Wall Street, raising over $38 million in its initial public stock offering. Lacking marketed products or substantial profit, the firm nonetheless saw its share price escalate from $35 to $89 in the first few minutes of trading, at that point the largest gain in stock market history. Coming at a time of economic recession and declining technological competitiveness in the United States, the event provoked banner headlines and ignited a period of speculative frenzy over biotechnology as a revolutionary means for creating new and better kinds of pharmaceuticals, untold profit, and a possible solution to national economic malaise. Drawing from an unparalleled collection of interviews with early biotech players, Sally Smith Hughes offers the first book-length history of this pioneering company, depicting Genentech’s improbable creation, precarious youth, and ascent to immense prosperity. Hughes provides intimate portraits of the people significant to Genentech’s science and business, including cofounders Herbert Boyer and Robert Swanson, and in doing so sheds new light on how personality affects the growth of science. By placing Genentech’s founders, followers, opponents, victims, and beneficiaries in context, Hughes also demonstrates how science interacts with commercial and legal interests and university research, and with government regulation, venture capital, and commercial profits. Integrating the scientific, the corporate, the contextual, and the personal, Genentech tells the story of biotechnology as it is not often told, as a risky and improbable entrepreneurial venture that had to overcome a number of powerful forces working against it.

Connected Strategy

Author : Nicolaj Siggelkow
Publisher : Harvard Business Press
ISBN 13 : 1633697010
Total Pages : 157 pages
Book Rating : 4.6/5 (336 download)

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Book Synopsis Connected Strategy by : Nicolaj Siggelkow

Download or read book Connected Strategy written by Nicolaj Siggelkow and published by Harvard Business Press. This book was released on 2019-04-30 with total page 157 pages. Available in PDF, EPUB and Kindle. Book excerpt: Business Models for Transforming Customer Relationships What if there were a way to turn occasional, sporadic transactions with customers into long-term, continuous relationships--while simultaneously driving dramatic improvements in operational efficiency? What if you could break your existing trade-offs between superior customer experience and low cost? This is the promise of a connected strategy. New forms of connectivity--involving frequent, low-friction, customized interactions--mean that companies can now anticipate customer needs as they arise, or even before. Simultaneously, enabled by these technologies, companies can create new business models that deliver more value to customers. Connected strategies are win-win: Customers get a dramatically improved experience, while companies boost operational efficiency. In this book, strategy and operations experts Nicolaj Siggelkow and Christian Terwiesch reveal the emergence of connected strategies as a new source of competitive advantage. With in-depth examples from companies operating in industries such as healthcare, financial services, mobility, retail, entertainment, nonprofit, and education, Connected Strategy identifies the four pathways--respond-to-desire, curated offering, coach behavior, and automatic execution--for turning episodic interactions into continuous relationships. The authors show how each pathway creates a competitive advantage, then guide you through the critical decisions for creating and implementing your own connected strategies. Whether you're trying to revitalize strategy in an established company or disrupt an industry as a startup, this book will help you: Reshape your connections with your customers Find new ways to connect with existing suppliers while also activating new sources of capacity Create the right revenue model Make the best technology choices to support your strategy Integrating rich examples, how-to advice, and practical tools in the form of "workshop chapters" throughout, this book is the ultimate resource for creating competitive advantage through connected relationships with your customers and redefined connections in your industry.

Testosterone Rex: Myths of Sex, Science, and Society

Author : Cordelia Fine
Publisher : W. W. Norton & Company
ISBN 13 : 0393253880
Total Pages : 320 pages
Book Rating : 4.3/5 (932 download)

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Book Synopsis Testosterone Rex: Myths of Sex, Science, and Society by : Cordelia Fine

Download or read book Testosterone Rex: Myths of Sex, Science, and Society written by Cordelia Fine and published by W. W. Norton & Company. This book was released on 2017-01-24 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: “Beliefs about men and women are as old as humanity itself, but Fine’s funny, spiky book gives reason to hope that we’ve heard Testosterone rex’s last roar.” —Annie Murphy Paul, New York Times Book Review Many people believe that, at its core, biological sex is a fundamental force in human development. According to this false-yet-familiar story, the divisions between men and women are in nature alone and not part of culture. Drawing on evolutionary science, psychology, neuroscience, endocrinology, and philosophy, Testosterone Rex disproves this ingrained myth and calls for a more equal society based on both sexes’ full human potential.

Life at the Speed of Light

Author : J. Craig Venter
Publisher : Penguin
ISBN 13 : 0143125907
Total Pages : 239 pages
Book Rating : 4.1/5 (431 download)

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Book Synopsis Life at the Speed of Light by : J. Craig Venter

Download or read book Life at the Speed of Light written by J. Craig Venter and published by Penguin. This book was released on 2014-09-30 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: “Venter instills awe for biology as it is, and as it might become in our hands.” —Publishers Weekly On May 20, 2010, headlines around the world announced one of the most extraordinary accomplishments in modern science: the creation of the world’s first synthetic lifeform. In Life at the Speed of Light, scientist J. Craig Venter, best known for sequencing the human genome, shares the dramatic account of how he led a team of researchers in this pioneering effort in synthetic genomics—and how that work will have a profound impact on our existence in the years to come. This is a fascinating and authoritative study that provides readers an opportunity to ponder afresh the age-old question “What is life?” at the dawn of a new era of biological engineering.

The Code Breaker -- Young Readers Edition

Author : Walter Isaacson
Publisher : Simon and Schuster
ISBN 13 : 1665910674
Total Pages : 336 pages
Book Rating : 4.6/5 (659 download)

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Book Synopsis The Code Breaker -- Young Readers Edition by : Walter Isaacson

Download or read book The Code Breaker -- Young Readers Edition written by Walter Isaacson and published by Simon and Schuster. This book was released on 2023-03-28 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Walter Isaacson’s #1 New York Times bestselling history of our third scientific revolution: CRISPR, gene editing, and the quest to understand the code of life itself, is now adapted for young readers! When Jennifer Doudna was a sixth grader in Hilo, Hawaii, she came home from school one afternoon and found a book on her bed. It was The Double Helix, James Watson’s account of how he and Francis Crick had discovered the structure of DNA, the spiral-staircase molecule that carries the genetic instruction code for all forms of life. This book guided Jennifer Doudna to focus her studies not on DNA, but on what seemed to take a backseat in biochemistry: figuring out the structure of RNA, a closely related molecule that enables the genetic instructions coded in DNA to express themselves. Doudna became an expert in determining the shapes and structures of these RNA molecules—an expertise that led her to develop a revolutionary new technique that could edit human genes. Today gene-editing technologies such as CRISPR are already being used to eliminate simple genetic defects that cause disorders such as Tay-Sachs and sickle cell anemia. For now, however, Jennifer and her team are being deployed against our most immediate threat—the coronavirus—and you have just been given a front row seat to that race.

The God Con

Author : Lee Moller
Publisher : FriesenPress
ISBN 13 : 1525506803
Total Pages : 248 pages
Book Rating : 4.5/5 (255 download)

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Book Synopsis The God Con by : Lee Moller

Download or read book The God Con written by Lee Moller and published by FriesenPress. This book was released on 2017-06-24 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: The crucifix is in! You can fool most of the people most of the time. In The God Con, Lee Moller, a life-long atheist and skeptic, looks at organized religion through the lens of the con. Organized religion has been selling an invisible product, that it never has to deliver, for thousands of years. It has given us bigotry, rampant pedophilia, terrorism, and bloodshed beyond imagining. And its acolytes have, in turn, given organized religion power over their bank accounts, their reproduction, and their very “souls”.