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Studies Towards The Total Synthesis Of Thapsigargin
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Book Synopsis Studies Towards the Total Synthesis of Thapsigargin by : C. J. Cowburn
Download or read book Studies Towards the Total Synthesis of Thapsigargin written by C. J. Cowburn and published by . This book was released on 2004 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Studies Towards the Total Synthesis of Thapsigargin by :
Download or read book Studies Towards the Total Synthesis of Thapsigargin written by and published by . This book was released on 1994 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Studies Directed Towards the Total Synthesis of Altohyrtin A. by : Pierre D. Kary
Download or read book Studies Directed Towards the Total Synthesis of Altohyrtin A. written by Pierre D. Kary and published by . This book was released on 1998 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Total Synthesis and SAR of Thapsigargin and Related Analogues and Mechanistic Studies of Perovskite-mediated Suzuki Reactions by : S. P. Andrews
Download or read book Total Synthesis and SAR of Thapsigargin and Related Analogues and Mechanistic Studies of Perovskite-mediated Suzuki Reactions written by S. P. Andrews and published by . This book was released on 2007 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Studies towards the total synthesis of FR182877 by : Frederick Woolf Goldberg
Download or read book Studies towards the total synthesis of FR182877 written by Frederick Woolf Goldberg and published by . This book was released on 2004 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Synthetic Studies Towards the Total Synthesis of Lancifodilactone G. by : Sanil Sreekumar
Download or read book Synthetic Studies Towards the Total Synthesis of Lancifodilactone G. written by Sanil Sreekumar and published by . This book was released on 2011 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This thesis presents our studies towards the first total synthesis of the novel anti- HIV agent lancifodilactone G, which has a highly unusual aliphatic enol. The first chapter provides a survey of architecturally diverse nortriterpenoids that were isolated from the Schisandraceae family. A proposed biosynthetic pathway for lancifodilactone G and closely related natural products provides a rationale for the formation of the consecutive 7/8/5 fused carbo cycles that are unique to Schisandra nortriterpenoids. Chapter 1 goes on to outline the reported strategies to access the core of lancifodilactone G and concludes with a retrosynthetic analysis proposed by the Evans group, which includes a biosynthetically inspired single-pot polycyclisation reaction. Chapter 2 describes the highly stereocontrolled synthesis of the eastern fragment (F-G rings) using transition metal-mediated Pauson-Khand reaction. This chapter also reviews the metal-mediated diastereoselective Pauson-Khand reaction directed by the stereogenic centre at C2, with the ample illustration to total synthesis. Attempted strategies for the assembly of the bicyclic cyclopentanone motif via a dienyl Pauson-Khand reaction of silicon- and oxygen- tethered diene-enes are presented. The failure of these strategies at different stages of the synthesis resulted in the exploration of a classical Pauson-Khand approach, which successfully furnished the eastern fragment. Finally, a second-generation synthesis is described which provided the fully functionalised eastern fragment with improved efficiency and overall yield. Chapter 3 discusses the successful synthesis of the western fragment (B-C rings) using a diastereoselective [4+3] cycloaddition strategy. Attempted strategies for the synthesis of the key 2,3-disubstituted furan derivative are presented, which was achieved via a hetero Pauson- Khand reaction. This chapter includes a brief account of the classical [4+3] cycloaddition reactions of furans using an in situ generated oxyallyl cation and also employing vinyl carbenoids in the metal-catalysed version. The review also highlights the application of the [4+ 3] cycloaddition reaction in the expeditious assembly of functionalised 7-membered rings that occur in a number of important biologically active natural products. The third chapter goes on to describe the application of these cycloaddition reactions in the synthesis of the fully functionalised western fragment of Lancifodilactone G. Chapter 4 describes a model study aimed at expediting the synthesis of the western fragment using a rhodium-catalysed allylic substitution reaction. A brief mechanistic discussion on unique aspects of the allylic alkylation reaction is illustrated. Chapter 4 concludes by outlining the coupling strategy for eastern and western fragments and the end game studies for the completion of the synthesis of lancifodilactone G.
Book Synopsis Studies Towards the Total Synthesis Or Ouabain by : Grazia Piizzi, 1970-
Download or read book Studies Towards the Total Synthesis Or Ouabain written by Grazia Piizzi, 1970- and published by . This book was released on 2004 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Studies Towards the Total Synthesis of the Epothilones A and B. by : Jane Elaine Fletcher
Download or read book Studies Towards the Total Synthesis of the Epothilones A and B. written by Jane Elaine Fletcher and published by . This book was released on 2000 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Studies Towards the Total Synthesis of Merrilactone A by : Karsten Meyer
Download or read book Studies Towards the Total Synthesis of Merrilactone A written by Karsten Meyer and published by . This book was released on 2009 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Studies Towards the Total Synthesis of Merrilactone A by : Jone Iriondo-Alberdi
Download or read book Studies Towards the Total Synthesis of Merrilactone A written by Jone Iriondo-Alberdi and published by . This book was released on 2007 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Studies Towards the Total Synthesis of 15G256upsilon by :
Download or read book Studies Towards the Total Synthesis of 15G256upsilon written by and published by . This book was released on 2003 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Studies Towards a Total Synthesis of Hippeastrine by : Johanna Myriam Helary
Download or read book Studies Towards a Total Synthesis of Hippeastrine written by Johanna Myriam Helary and published by . This book was released on 2015 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Synthetic Studies Towards the Total Synthesis of Tuberostemonine by : Lilian Ai Cheng Low
Download or read book Synthetic Studies Towards the Total Synthesis of Tuberostemonine written by Lilian Ai Cheng Low and published by . This book was released on 1998 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Studies Towards the Total Synthesis of Labiatin A by : Serena Carosso
Download or read book Studies Towards the Total Synthesis of Labiatin A written by Serena Carosso and published by . This book was released on 2011 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Studies Directed Towards the Total Synthesis of the Natural Products Avarol and Capentin by : Thomas Elliott Jacks
Download or read book Studies Directed Towards the Total Synthesis of the Natural Products Avarol and Capentin written by Thomas Elliott Jacks and published by . This book was released on 1993 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Studies Towards the Total Synthesis of Tetrodecamycin by : Jing He
Download or read book Studies Towards the Total Synthesis of Tetrodecamycin written by Jing He and published by . This book was released on 2007 with total page 578 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Studies towards the total synthesis of obtusallene IV by : Roshni Bhuva
Download or read book Studies towards the total synthesis of obtusallene IV written by Roshni Bhuva and published by . This book was released on 2005 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: