Studies Of Some Biologically Important Metal Complexes

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Inorganic and Organometallic Transition Metal Complexes with Biological Molecules and Living Cells

Author : Kenneth Kam-Wing Lo
Publisher : Academic Press
ISBN 13 : 012803887X
Total Pages : 408 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Inorganic and Organometallic Transition Metal Complexes with Biological Molecules and Living Cells by : Kenneth Kam-Wing Lo

Download or read book Inorganic and Organometallic Transition Metal Complexes with Biological Molecules and Living Cells written by Kenneth Kam-Wing Lo and published by Academic Press. This book was released on 2016-12-30 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inorganic and Organometallic Transition Metal Complexes with Biological Molecules and Living Cells provides a complete overview of this important research area that is perfect for both newcomers and expert researchers in the field. Through concise chapters written and edited by esteemed experts, this book brings together a comprehensive treatment of the area previously only available through scattered, lengthy review articles in the literature. Advanced topics of research are covered, with particular focus on recent advances in the biological applications of transition metal complexes, including inorganic medicine, enzyme inhibitors, antiparasital agents, and biological imaging reagents. - Geared toward researchers and students who seek an introductory overview of the field, as well as researchers working in advanced areas - Focuses on the interactions of inorganic and organometallic transition metal complexes with biological molecules and live cells - Foscuses on the fundamentals and their potential therapeutic and diagnostic applications - Covers recent biological applications of transition metal complexes, such as anticancer drugs, enzyme inhibitors, bioconjugation agents, chemical biology tools, and bioimaging reagents

Inorganic Biochemistry

Author : J. A. Cowan
Publisher : John Wiley & Sons
ISBN 13 : 9780471188957
Total Pages : 458 pages
Book Rating : 4.1/5 (889 download)

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Book Synopsis Inorganic Biochemistry by : J. A. Cowan

Download or read book Inorganic Biochemistry written by J. A. Cowan and published by John Wiley & Sons. This book was released on 1997-03-21 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: Das erfolgreiche Werk des jungen, kreativen Autors jetzt in aktualisierter und korrigierter Auflage! Der Text wurde um Fragenkomplexe und Übungsbeispiele, teils mit Lösungen, erweitert; dies empfiehlt ihn besonders zur Ergänzung einer Vorlesung.

Metal Complexes in Aqueous Solutions

Author : Arthur E. Martell
Publisher : Springer Science & Business Media
ISBN 13 : 1489914862
Total Pages : 259 pages
Book Rating : 4.4/5 (899 download)

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Book Synopsis Metal Complexes in Aqueous Solutions by : Arthur E. Martell

Download or read book Metal Complexes in Aqueous Solutions written by Arthur E. Martell and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 259 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stability constants are fundamental to understanding the behavior of metal ions in aqueous solution. Such understanding is important in a wide variety of areas, such as metal ions in biology, biomedical applications, metal ions in the environment, extraction metallurgy, food chemistry, and metal ions in many industrial processes. In spite of this importance, it appears that many inorganic chemists have lost an appreciation for the importance of stability constants, and the thermodynamic aspects of complex formation, with attention focused over the last thirty years on newer areas, such as organometallic chemistry. This book is an attempt to show the richness of chemistry that can be revealed by stability constants, when measured as part of an overall strategy aimed at understanding the complexing properties of a particular ligand or metal ion. Thus, for example, there are numerous crystal structures of the Li+ ion with crown ethers. What do these indicate to us about the chemistry of Li+ with crown ethers? In fact, most of these crystal structures are in a sense misleading, in that the Li+ ion forms no complexes, or at best very weak complexes, with familiar crown ethers such as l2-crown-4, in any known solvent. Thus, without the stability constants, our understanding of the chemistry of a metal ion with any particular ligand must be regarded as incomplete. In this book we attempt to show how stability constants can reveal factors in ligand design which could not readily be deduced from any other physical technique.

Spectroscopic Analyses

Author : Eram Sharmin
Publisher : BoD – Books on Demand
ISBN 13 : 9535136275
Total Pages : 242 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Spectroscopic Analyses by : Eram Sharmin

Download or read book Spectroscopic Analyses written by Eram Sharmin and published by BoD – Books on Demand. This book was released on 2017-12-06 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book presents developments and applications of these methods, such as NMR, mass, and others, including their applications in pharmaceutical and biomedical analyses. The book is divided into two sections. The first section covers spectroscopic methods, their applications, and their significance as characterization tools; the second section is dedicated to the applications of spectrophotometric methods in pharmaceutical and biomedical analyses. This book would be useful for students, scholars, and scientists engaged in synthesis, analyses, and applications of materials/polymers.

NMR Spectroscopy

Author : Harald Günther
Publisher : John Wiley & Sons
ISBN 13 : 3527674772
Total Pages : 842 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis NMR Spectroscopy by : Harald Günther

Download or read book NMR Spectroscopy written by Harald Günther and published by John Wiley & Sons. This book was released on 2013-12-13 with total page 842 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nuclear magnetic resonance (NMR) spectroscopy is one of the most powerful and widely used techniques in chemical research for investigating structures and dynamics of molecules. Advanced methods can even be utilized for structure determinations of biopolymers, for example proteins or nucleic acids. NMR is also used in medicine for magnetic resonance imaging (MRI). The method is based on spectral lines of different atomic nuclei that are excited when a strong magnetic field and a radiofrequency transmitter are applied. The method is very sensitive to the features of molecular structure because also the neighboring atoms influence the signals from individual nuclei and this is important for determining the 3D-structure of molecules. This new edition of the popular classic has a clear style and a highly practical, mostly non-mathematical approach. Many examples are taken from organic and organometallic chemistry, making this book an invaluable guide to undergraduate and graduate students of organic chemistry, biochemistry, spectroscopy or physical chemistry, and to researchers using this well-established and extremely important technique. Problems and solutions are included.

Medicinal Inorganic Chemistry

Author : Jonathan L. Sessler
Publisher :
ISBN 13 :
Total Pages : 480 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Medicinal Inorganic Chemistry by : Jonathan L. Sessler

Download or read book Medicinal Inorganic Chemistry written by Jonathan L. Sessler and published by . This book was released on 2005 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews the current diagnostic and therapeutic uses of metal-containing compounds in medicine, as well as the role of metals in disease.

Studies of Some Novel Coordination Compounds and their Application in Nanoparticle Synthesis

Author : Nidhi Rai
Publisher : GRIN Verlag
ISBN 13 : 3668654646
Total Pages : 134 pages
Book Rating : 4.6/5 (686 download)

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Book Synopsis Studies of Some Novel Coordination Compounds and their Application in Nanoparticle Synthesis by : Nidhi Rai

Download or read book Studies of Some Novel Coordination Compounds and their Application in Nanoparticle Synthesis written by Nidhi Rai and published by GRIN Verlag. This book was released on 2018-03-07 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific Study from the year 2018 in the subject Chemistry - Anorganic Chemistry, grade: 10, , language: English, abstract: Nanoscience is the study of phenomena exhibited by materials at atomic, molecular and macromolecular levels, of dimensions ranging from a few nanometres to less than a hundred nanometres. In chemistry, this size range has been associated with colloids, micelles, polymer molecules and similar structures. In physical and electrical engineering, nanoscience is often associated with quantum behaviour, and electron behaviour in nanoscale structures. The area of research in the field of nanotechnology is as diverse as physics, chemistry, material science, microbiology, biochemistry and also molecular biology. The interface of nanotechnology in combination with biotechnology and biomedical engineering has emerged with the use of nanoscale structures in diagnosis, gene sequencing, and drug delivery. Nanoparticles have attracted great interest in recent years because of their unique chemical and physical properties, which are different from those of either the bulk materials or single atoms. Nanostructure materials have potential applications in ceramics, optoelectronics and catalysis. Research on the synthesis of nanomaterials using metal complexes as precursors have been less reported. Application of metal complexes as precursors may be helpful to control the physical properties of metal nanoparticles. In the last few years, researchers have characterized the tunable properties by altering the nanostructure size, shape, and chemical composition and have developed reproducible strategies to make nanostructures of desired properties. It has been already proved that by controlling the size of the particle and manipulating surface structures of the semiconductor materials, the electronic, magnetic, mechanical, and chemical properties can be modified to suit a wide range of device application in many fields. The present book deals with the synthesis of Schiff base complexes of Cd(II), Zn(II) and Hg(II) with different sulphur containing ligand and preparation of metal sulphide nanoparticle by the thermal decomposition of complex precursor. During this academic journey four new sulphur containing ligands and their thirty complexes were synthesized. These ligands and complexes were characterized by spectroscopic methods like UV-Vis, FT-IR, 1H-NMR, 13C-NMR, 2D-NMR, FAB-MS / ESI-Ms spectra.

Metal Transporters

Author : Jose M. Arguello
Publisher : Academic Press
ISBN 13 : 0123943906
Total Pages : 478 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Metal Transporters by : Jose M. Arguello

Download or read book Metal Transporters written by Jose M. Arguello and published by Academic Press. This book was released on 2012-10-25 with total page 478 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of Current Topics in Membranes focuses on metal transmembrane transporters and pumps, a recently discovered family of membrane proteins with many important roles in the physiology of living organisms. The book summarizes the most recent advances in the field of metal ion transport and provides a broad overview of the major classes of transporters involved in homeostasis of heavy metals. Various families of the transporters and metal specificities are discussed with the focus on the structural and mechanistic aspects of their function and regulation. The reader will access information obtained through a variety of approaches ranging from X-ray crystallography to cell biology and bioinformatics, which have been applied to transporters identified in diverse biological systems, such as pathogenic bacteria, plants, humans and others. Field is cutting-edge and a lot of the information is new to research community Wide breadth of topic coverage Contributors of high renown and expertise

Direct Synthesis of Metal Complexes

Author : B.I. Kharisov
Publisher : Elsevier
ISBN 13 : 0128110627
Total Pages : 470 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Direct Synthesis of Metal Complexes by : B.I. Kharisov

Download or read book Direct Synthesis of Metal Complexes written by B.I. Kharisov and published by Elsevier. This book was released on 2018-04-19 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt: Direct Synthesis of Metal Complexes provides in-depth coverage of the direct synthesis of coordination and organometallic compounds. The work is primarily organized by methods, but also covers highly relevant complexes, such as metal-polymer coordination compounds. This updated reference discusses recent developments in cryosynthesis, electrosynthesis, and tribosynthesis (popular as it doesn't require organic solvents), with special attention paid to 'greener' methodologies and approaches. Additionally, the book describes physical methods of zero-valent metal interaction with organic matter, including sputtering, ultrasonic treatment and synthesis in ionic liquids. The book presents completely new content as a follow-up to the 1999 Elsevier Science publication Direct Synthesis of Coordination and Organometallic Compounds that was edited by Dr. Garnovskii and Dr. Kharisov. - Covers current methods and techniques of metal interactions with organic media leading to metal chelates, adducts, di- and polymetallic complexes, metal-containing macrocycles, supported coordination compounds (i.e., metal complexes on carbon nanotubes), and more - Describes reactivities of distinct forms of elemental metals (powders, sheets, nanoparticles (including a host of less-common metal nanostructures) with organic phase (liquid, solid and gaseous) and water - Includes experimental procedures, with examples of direct synthesis, at the end of each chapter

Ligand Design in Medicinal Inorganic Chemistry

Author : Tim Storr
Publisher : John Wiley & Sons
ISBN 13 : 1118697898
Total Pages : 650 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Ligand Design in Medicinal Inorganic Chemistry by : Tim Storr

Download or read book Ligand Design in Medicinal Inorganic Chemistry written by Tim Storr and published by John Wiley & Sons. This book was released on 2014-06-12 with total page 650 pages. Available in PDF, EPUB and Kindle. Book excerpt: Increasing the potency of therapeutic compounds, while limiting side-effects, is a common goal in medicinal chemistry. Ligands that effectively bind metal ions and also include specific features to enhance targeting, reporting, and overall efficacy are driving innovation in areas of disease diagnosis and therapy. Ligand Design in Medicinal Inorganic Chemistry presents the state-of-the-art in ligand design for medicinal inorganic chemistry applications. Each individual chapter describes and explores the application of compounds that either target a disease site, or are activated by a disease-specific biological process. Ligand design is discussed in the following areas: Platinum, Ruthenium, and Gold-containing anticancer agents Emissive metal-based optical probes Metal-based antimalarial agents Metal overload disorders Modulation of metal-protein interactions in neurodegenerative diseases Photoactivatable metal complexes and their use in biology and medicine Radiodiagnostic agents and Magnetic Resonance Imaging (MRI) agents Carbohydrate-containing ligands and Schiff-base ligands in Medicinal Inorganic Chemistry Metalloprotein inhibitors Ligand Design in Medicinal Inorganic Chemistry provides graduate students, industrial chemists and academic researchers with a launching pad for new research in medicinal chemistry.

Metal Complex - DNA Interactions

Author : Nick Hadjiliadis
Publisher : John Wiley & Sons
ISBN 13 : 9781405194105
Total Pages : 544 pages
Book Rating : 4.1/5 (941 download)

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Book Synopsis Metal Complex - DNA Interactions by : Nick Hadjiliadis

Download or read book Metal Complex - DNA Interactions written by Nick Hadjiliadis and published by John Wiley & Sons. This book was released on 2009-03-30 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metal ions and metal complexes have long been recognized ascritically important components of nucleic acid chemistry, both inregulation of gene expression and as promising therapeutic agents.Understanding how metal complexes interact with DNA has become anactive research area at the interface between chemistry, molecularbiology and medicine. Metal Complex - DNA Interactions provides a comprehensiveoverview of this increasingly diverse field, presenting recentdevelopments and the latest research with particular emphasis onmetal-based drugs and metal ion toxicity. The text is divided intofour parts: Basic Structural and Kinetic Aspects: includes chapterson sequence-selective metal binding to DNA and thermodynamicmodels. Medical Applications: focuses on anticancer platinumdrugs, including discussions on DNA repair in antitumor effects ofplatinum drugs and photo-dynamic therapy. DNA-Recognition - Nucleases and Sensor: describesprobes for DNA recognition, artificial restriction agents,metallo-DNAzymes for metal sensing applications and metal iondependent catalysis in nucleic acid enzymes. Toxicological Aspects: deals with structural studies ofmercury–DNA interactions, chromium-induced DNA damage andrepair, and the effect of arsenic and nickel on DNAintegrity. This book will be a valuable resource for academic researchersand professionals from a range of pharmaceutical and chemicalindustries, particularly those involved in the development of newand less toxic anticancer metallo-drugs, and in the field ofenvironmental and toxicological chemistry.

NanoBioMedicine

Author : Shailendra K. Saxena
Publisher : Springer Nature
ISBN 13 : 9813298987
Total Pages : 510 pages
Book Rating : 4.8/5 (132 download)

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Book Synopsis NanoBioMedicine by : Shailendra K. Saxena

Download or read book NanoBioMedicine written by Shailendra K. Saxena and published by Springer Nature. This book was released on 2020-02-03 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of the recent trends in various Nanotechnology-based therapeutics and challenges associated with its development. Nanobiotechnology is an interdisciplinary research that has wide applications in the various fields of biomedical research. The book discusses the various facets of the application of Nanotechnology in drug delivery, clinical diagnostics, Nanomedicine and treatment of infectious and chronic diseases. The book also highlights the recent advancements on important devices and applications that are based on Nanotechnology in medicine and brief the regulatory and ethical issues related to nanomedical devices. It also reviews the toxicological profile of various nanomaterials and emphasizes the need for safe nanomaterials for clinical use. Finally, the book discusses the recent developments of potential commercial applications of Nanotechnology.

Electron Paramagnetic Resonance

Author : John A. Weil
Publisher : John Wiley & Sons
ISBN 13 : 0470084979
Total Pages : 690 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Electron Paramagnetic Resonance by : John A. Weil

Download or read book Electron Paramagnetic Resonance written by John A. Weil and published by John Wiley & Sons. This book was released on 2007-01-09 with total page 690 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an introduction to the underlying theory, fundamentals, and applications of EPR spectroscopy, as well as new developments in the area. Knowledge of the topics presented will allow the reader to interpret of a wide range of EPR spectra, as well as help them to apply EPR techniques to problem solving in a wide range of areas: organic, inorganic, biological, and analytical chemistry; chemical physics, geophysics, and minerology. Includes updated information on high frequency and multi-frequency EPR, pulsed microwave techniques and spectra analysis, dynamic effects, relaxation phenomena, computer-based spectra simulation, biomedical aspects of EPR, and more Equips readers with sufficient knowledge of EPR techniques to go on in their specialized area of interest Provides problem sets and concise bibliographies at the end of each chapter, plus several tutorial appendices on topics like mathematical operations, quantum mechanics of angular momentum, experimental considerations.

Metal Ions in Bio-Imaging Techniques

Author : Astrid Sigel
Publisher : Walter de Gruyter GmbH & Co KG
ISBN 13 : 3110685701
Total Pages : 547 pages
Book Rating : 4.1/5 (16 download)

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Book Synopsis Metal Ions in Bio-Imaging Techniques by : Astrid Sigel

Download or read book Metal Ions in Bio-Imaging Techniques written by Astrid Sigel and published by Walter de Gruyter GmbH & Co KG. This book was released on 2021-03-08 with total page 547 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 22, entitled Metal Ions in Bio-Imaging Techniques, of the series Metal Ions in Life Sciences deals with metal ions as tools in imaging. This dates back to the first half of the past century, when barium sulfate was orally given to patients undergoing X-ray examination. The use of contrast agents has since developed into a large interdisciplinary field encompassing not only medicine, but also chemistry, material sciences, physics, biology, engineering, and computer sciences. MILS-22 provides deep and current insights in 17 stimulating chapters on the new research frontiers of this fast growing field on bio-imaging ... and beyond. For example, adding bio-sensing yields theranostic agents, meaning diagnosis and therapy linked in the same molecule; ions of Gd, Mn, Fe, Co, Ir, 99mTc, etc., are involved. Other important topics are, e.g., metal complexes in paramagnetic Chemical Exchange Transfer (paraCEST), radiometals for Positron Emission Tomography (PET) imaging, or paramagnetic metal ion probes for 19F magnetic resonance imaging. MILS-22 is written by 57 internationally recognized experts from 12 countries, that is, from the US via Europe to China. The impact of this vibrant research area is manifested by more than 2300 references and nearly 120 figures, mostly in color, and several informative tables. To conclude, Metal Ions in Bio-Imaging Techniques is an essential resource for scientists working in the wide range from material sciences, enzymology, analytic, organic, and inorganic biochemistry all the way through to medicine including the clinic ... not forgetting that also excellent information for teaching is provided.

Hard and Soft Acids and Bases

Author : Ralph G. Pearson
Publisher : Hutchinson Ross Publishing Company
ISBN 13 :
Total Pages : 500 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Hard and Soft Acids and Bases by : Ralph G. Pearson

Download or read book Hard and Soft Acids and Bases written by Ralph G. Pearson and published by Hutchinson Ross Publishing Company. This book was released on 1973 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Biological Inorganic Chemistry

Author : Ivano Bertini
Publisher : University Science Books
ISBN 13 : 9781891389436
Total Pages : 794 pages
Book Rating : 4.3/5 (894 download)

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Book Synopsis Biological Inorganic Chemistry by : Ivano Bertini

Download or read book Biological Inorganic Chemistry written by Ivano Bertini and published by University Science Books. This book was released on 2007 with total page 794 pages. Available in PDF, EPUB and Kindle. Book excerpt: Part A.: Overviews of biological inorganic chemistry : 1. Bioinorganic chemistry and the biogeochemical cycles -- 2. Metal ions and proteins: binding, stability, and folding -- 3. Special cofactors and metal clusters -- 4. Transport and storage of metal ions in biology -- 5. Biominerals and biomineralization -- 6. Metals in medicine. -- Part B.: Metal ion containing biological systems : 1. Metal ion transport and storage -- 2. Hydrolytic chemistry -- 3. Electron transfer, respiration, and photosynthesis -- 4. Oxygen metabolism -- 5. Hydrogen, carbon, and sulfur metabolism -- 6. Metalloenzymes with radical intermediates -- 7. Metal ion receptors and signaling. -- Cell biology, biochemistry, and evolution: Tutorial I. -- Fundamentals of coordination chemistry: Tutorial II.

Machine Learning in Chemistry

Author : Jon Paul Janet
Publisher : American Chemical Society
ISBN 13 : 0841299005
Total Pages : 189 pages
Book Rating : 4.8/5 (412 download)

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Book Synopsis Machine Learning in Chemistry by : Jon Paul Janet

Download or read book Machine Learning in Chemistry written by Jon Paul Janet and published by American Chemical Society. This book was released on 2020-05-28 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent advances in machine learning or artificial intelligence for vision and natural language processing that have enabled the development of new technologies such as personal assistants or self-driving cars have brought machine learning and artificial intelligence to the forefront of popular culture. The accumulation of these algorithmic advances along with the increasing availability of large data sets and readily available high performance computing has played an important role in bringing machine learning applications to such a wide range of disciplines. Given the emphasis in the chemical sciences on the relationship between structure and function, whether in biochemistry or in materials chemistry, adoption of machine learning by chemistsderivations where they are important