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Studies Directed Towards The Development Of An In Vitro Method For The Site Specific Incorporation Of Unnatural Amino Acids Into Proteins Using Unassigned Codons In Micrococcus Luteus
Download Studies Directed Towards The Development Of An In Vitro Method For The Site Specific Incorporation Of Unnatural Amino Acids Into Proteins Using Unassigned Codons In Micrococcus Luteus full books in PDF, epub, and Kindle. Read online Studies Directed Towards The Development Of An In Vitro Method For The Site Specific Incorporation Of Unnatural Amino Acids Into Proteins Using Unassigned Codons In Micrococcus Luteus ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Book Synopsis Studies Directed Towards the Development of an in Vitro Method for the Site-specific Incorporation of Unnatural Amino Acids Into Proteins Using Unassigned Codons in Micrococcus Luteus by : Anne Kathryn Kowal
Download or read book Studies Directed Towards the Development of an in Vitro Method for the Site-specific Incorporation of Unnatural Amino Acids Into Proteins Using Unassigned Codons in Micrococcus Luteus written by Anne Kathryn Kowal and published by . This book was released on 1996 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Dissertation Abstracts International by :
Download or read book Dissertation Abstracts International written by and published by . This book was released on 1997 with total page 860 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis A General Method for Site-specific Incorporation of Unnatural Amino Acids Into Proteins by : Christopher J. Noren
Download or read book A General Method for Site-specific Incorporation of Unnatural Amino Acids Into Proteins written by Christopher J. Noren and published by . This book was released on 1989 with total page 7 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Site-specific Incorporation of Unnatural Amino Acid Into Protein in Vivo by : Kiket Avi Omer Makoubi
Download or read book Site-specific Incorporation of Unnatural Amino Acid Into Protein in Vivo written by Kiket Avi Omer Makoubi and published by . This book was released on 2012 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Site Specific Incorporation of Amino Acid Analogues Into Proteins In Vivo by :
Download or read book Site Specific Incorporation of Amino Acid Analogues Into Proteins In Vivo written by and published by . This book was released on 2010 with total page 55 pages. Available in PDF, EPUB and Kindle. Book excerpt: The goal of this project is to develop methods for the site-specific insertion in vivo of one or more amino acid analogues into proteins in eubacteria and in eukaryotes. The amino acids to be used include those that are photoactivatable, those that are fluorescent, those that carry reactive side chains such as keto groups, heavy atoms such as iodine, those that act as spectroscopic probes, and those that mimic phosphoserine, phosphothreonine, or phosphotyrosine. Besides providing a method for the production of new biomateirals with novel chemical and biological properties, proteins carrying such amino acid analogues will have wide applications in biology. These include studies on the folding, structure, stability and function of proteins, protein-protein interactions, protein localization and protein dynamics in vivo and signal transduction.
Book Synopsis Molecular Biology and Pathogenicity of Mycoplasmas by : Shmuel Razin
Download or read book Molecular Biology and Pathogenicity of Mycoplasmas written by Shmuel Razin and published by Springer Science & Business Media. This book was released on 2007-05-08 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt: was the result of the efforts of Robert Cleverdon. The rapidly developing discipline of molecular biology and the rapidly expanding knowledge of the PPLO were brought together at this meeting. In addition to the PPLO specialists, the conference invited Julius Marmur to compare PPLO DNA to DNA of other organisms; David Garfinkel, who was one of the first to develop computer models of metabolism; Cyrus Levinthal to talk about coding; and Henry Quastler to discuss information theory constraints on very small cells. The conference was an announcement of the role of PPLO in the fundamental understanding of molecular biology. Looking back 40-some years to the Connecticut meeting, it was a rather bold enterprise. The meeting was international and inter-disciplinary and began a series of important collaborations with influences resonating down to the present. If I may be allowed a personal remark, it was where I first met Shmuel Razin, who has been a leading figure in the emerging mycoplasma research and a good friend. This present volume is in some ways the fulfillment of the promise of that early meeting. It is an example of the collaborative work of scientists in building an understanding of fundamental aspects of biology.
Book Synopsis Engineering the Genetic Code by : Nediljko Budisa
Download or read book Engineering the Genetic Code written by Nediljko Budisa and published by John Wiley & Sons. This book was released on 2006-05-12 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ability to introduce non-canonical amino acids in vivo has greatly expanded the repertoire of accessible proteins for basic research and biotechnological application. Here, the different methods and strategies to incorporate new or modified amino acids are explained in detail, including a lot of practical advice for first-time users of this powerful technique. Novel applications in protein biochemistry, genomics, biotechnology and biomedicine made possible by the expansion of the genetic code are discussed and numerous examples are given. Essential reading for all molecular life scientists who want to stay ahead in their research.
Book Synopsis Evolution of the Genetic Code by : Shōzō Ōsawa
Download or read book Evolution of the Genetic Code written by Shōzō Ōsawa and published by . This book was released on 1995 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: The genetic code was deciphered experimentally around 1966 and for a number of years scientists considered it to be "universal" for all forms of life. In 1981 researchers shocked the scientific community with the discovery that the code differed in mitochondria and certain other organisms, evidence that the genetic code was still evolving. This book discusses the distribution and origin of the non-universal codes and examines the possible mechanisms of code changes, making it essential reading for all those interested in evolutionary genetics.
Book Synopsis Macrolide Antibiotics by : W. Schönfeld
Download or read book Macrolide Antibiotics written by W. Schönfeld and published by Birkhäuser. This book was released on 2012-12-06 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are only very few chemical classes of antibiotics in medical use, and these have originated over a span of more than 60 years of research. Almost half a century ago, the first member of the macrolides, erythromycin, was introduced as a treatment option for bacterial infections. Erythromycin is a very complex fermentation product obtained from the soil bacterium Saccharopolyspora ery thraea (originally named Streptomyces erythreus). The success of erythromycin, based on its efficacy and tolerability, stimulated researchers throughout the world to undertake intense efforts to understand the biology and chemistry of macrolides and to use this experience to improve the properties of this compound class. The second generation of macrolides, based on chemical modifications of erythromy cin, is currently being in broad use, especially for treatment of respiratory tract infections. We presently foresee the introduction of a new generation of macro lides, i. e. the ketolides, which have the potential to overcome rising resistance problems. This monograph is intended to give the interested reader an overview on "macrolide experience", covering important areas from basic research to clinical use. Starting from a historic overview, the essential basic parameters - efficacy, pharmacokinetics, pharmacodynamics, and pharmacology - are highlighted in order to introduce the reader to the rationale for clinical use of macrolides. The following group of chapters cover the complex chemistry of the macro lactone structures, giving historic background, basic structure-activity relation ships of various derivatization strategies, and perspectives for future discovery of new semisynthetic macrolide antibiotics.
Book Synopsis Cell-Free Protein Expression by : James R. Swartz
Download or read book Cell-Free Protein Expression written by James R. Swartz and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cell-free protein synthesis is coming of age! Motivated by an escalating need for efficient protein synthesis and empowered by readily accessible cell-free protein synthesis kits, the technology is expanding both in the range of feasible proteins and in the ways that proteins can be labeled and modified. This volume follows "Cell-Free Translation Systems", edited by Professor Alexander S. Spirin in 2002. Since then, an impressive collection of new work has emerged that demonstrates a substantial expansion of capability. In this volume, we show that proteins now can be efficiently produced using PCR products as DNA templates and that even membrane proteins and proteins with multiple disulfide proteins are obtained at high yields. Many additional advances are also presented. It is an exciting time for protein synthesis technology.
Book Synopsis Structural Genomics by : Yu Wai Chen
Download or read book Structural Genomics written by Yu Wai Chen and published by Humana. This book was released on 2013-11-09 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of Structural Genomics has produced many technological advances that transform and accelerate structure solution and analysis. Structural Genomics: General Applications emphasizes the benefits to the wider structural research community. It also reflects the current trend in tackling the more ambitious challenges of studying macromolecular machineries and complexes. Divided into three convenient sections, topics include the cloning and production of proteins for structural studies, experimental methods, and computational methods and data analysis. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Structural Genomics: General Applications aims primarily to channel spin-off technologies to the average structural biologist in a small or medium-sized laboratory.
Book Synopsis Computational Methods in Protein Evolution by : Tobias Sikosek
Download or read book Computational Methods in Protein Evolution written by Tobias Sikosek and published by Humana. This book was released on 2018-10-09 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents a diverse collection of methodologies used to study various problems at the protein sequence and structure level. The chapters in this book look at issues ranging from broad concepts like protein space to specifics like antibody modeling. Topics include point mutations, gene duplication, de novo emergence of new genes, pairwise correlated mutations, ancestral protein reconstruction, homology modelling, protein stability and dynamics, and protein-protein interactions. The book also covers a wide range of computational approaches, including sequence and structure alignments, phylogenies, physics-based and mathematical approaches, machine learning, and more. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and prerequisites, step-by-step, readily reproducible computational protocols (using command line or graphical user interfaces, sometimes including computer code), and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and authoritative, Computational Methods in Protein Evolution is a valuable resource that offers useful workflows and techniques that will help both novice and expert researchers working with proteins computationally.
Book Synopsis Computational Design of Ligand Binding Proteins by : Barry L. Stoddard
Download or read book Computational Design of Ligand Binding Proteins written by Barry L. Stoddard and published by Humana. This book was released on 2016-04-20 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a collection of protocols and approaches for the creation of novel ligand binding proteins, compiled and described by many of today's leaders in the field of protein engineering. Chapters focus on modeling protein ligand binding sites, accurate modeling of protein-ligand conformational sampling, scoring of individual docked solutions, structure-based design program such as ROSETTA, protein engineering, and additional methodological approaches. Examples of applications include the design of metal-binding proteins and light-induced ligand binding proteins, the creation of binding proteins that also display catalytic activity, and the binding of larger peptide, protein, DNA and RNA ligands. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Book Synopsis Industrial Enzymes and Their Applications by : Helmut Uhlig
Download or read book Industrial Enzymes and Their Applications written by Helmut Uhlig and published by John Wiley & Sons. This book was released on 1998-04-06 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt: * Ein ma?gebender Katalog technischer Enzyme, ihrer Charakteristika und industriellen Verwendung. * Durch die leicht verstandliche Einfuhrung zu jedem Kapitel sowie die Beschreibung der technischen Enzyme ist dieses Werk auch fur Neulinge auf diesem Gebiet mit fehlendem wissenschaftlichen Hintergrund bestens geeignet. * Enthalten sind Informationen uber konkurrierende Enzymprodukte, so da? der Leser aufgrund dieses Wissens Enzyme fur bestimmte Zwecke auswahlen kann. * Sehr praxisorientiert, mit mehr als 100 Abbildungen, die genau zeigen, wie Enzymcharakteristika entwickelt werden. In jedem Kapitel finden sich zum besseren Verstandnis der technischen Seite Flie?diagramme. * Spezielle Kapitel fur die Leder, Back-, Saft- und Weinindustrie (Die wichtigsten Verbraucher industrieller Enzyme); einschlie?lich einem geschichtlichen Abri? uber die Verwendung von Enzymen in der Industrie * Au?erdem enthalten: Gesetzesvorschriften zum Einsatz industrieller Enzyme. (01/98)
Book Synopsis Magnetic Resonance in Biological Systems by : A. Ehrenberg
Download or read book Magnetic Resonance in Biological Systems written by A. Ehrenberg and published by Elsevier. This book was released on 2013-09-24 with total page 441 pages. Available in PDF, EPUB and Kindle. Book excerpt: Magnetic Resonance in Biological Systems, Volume 9 is a collection of manuscripts presented at the Second International Conference on Magnetic Resonance in Biological Systems, held in Wenner-Gren Center, Stockholm, Sweden on June 1966. The conference is sponsored by International Union of Biochemistry Swedish Medical Research Council Swedish Natural Science Research Council Wenner-Gren Center Foundation for Scientific Research. This book contains 51 chapters, and begins with reviews of NMR investigations of biological macromolecules, including proteins, amino acids, and glycylglycine copper (II). Considerable chapters are devoted to numerous biological studies using the electronic paramagnetic resonance (EPR), thus introducing the branch of science called submolecular biology. This book also explores other applications of NMR and EPR, with special emphasis on blood component analysis and protein-metal complexes. The final chapters survey the principles and applications of Mössbauer spectroscopy. This book will prove useful to analytical chemists and biologists.
Book Synopsis The Aminoacyl-tRNA Synthetases by : Michael Ibba
Download or read book The Aminoacyl-tRNA Synthetases written by Michael Ibba and published by CRC Press. This book was released on 2005-04-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: By virtue of their role as catalysts of the aminoacylation reaction, the aminoacyl-tRNA synthetases ensure that the first step of translation is performed quickly and accurately. In this volume of 36 separate chapters, the many facets of this ancient and ubiquitous family are reviewed, including their surprising structural diversity, enzymology, tRNA interaction properties, and curious alternative functions. These chapters illustrate the degree to which the aminoacyl-tRNA synthetases employ a variety of mechanisms to carry out both the standard functions related to the synthesis of aminoacylated tRNA for protein synthesis, as well as the surprising functions associated with amino acid biosynthesis, cytokine function, and even the processivity of DNA replication. Other chapters explore the regulation of their synthesis, their role in disease, and their prospects as targets for antibacterial therapeutics. This monograph will be a valuable resource for all scientists interested in the fundamentals of protein synthesis from both a basic research and clinical perspective, as well as the relation of translational components to the evolution of the genetic code.
Book Synopsis Nature's Robots by : Charles Tanford
Download or read book Nature's Robots written by Charles Tanford and published by OUP Oxford. This book was released on 2003-11-27 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proteins are amazingly versatile molecules. They make the chemical reactions happen that form the basis for life, they transmit signals in the body, they identify and kill foreign invaders, they form the engines that make us move, and they record visual images. All of this is now common knowledge, but it was not so a hundred years ago. Nature's Robots is an authoritative history of protein science, from the origins of protein research in the nineteenth century, when the chemical constitution of 'protein' was first studied and heatedly debated and when there was as yet no glimmer of the functional potential of substances in the 'protein' category, to the determination of the first structures of individual proteins at atomic resolution - when positions of individual atoms were first specified exactly and bonding between neighbouring atoms precisely defined. Tanford and Reynolds, who themselves made major contributions to the golden age of protein science, have written a remarkably vivid account of this history. It is a fascinating story, involving heroes from the past, working mostly alone or in small groups, usually with little support from formal research groups. It is also a story that embraces a number of historically important scientific controversies. Written in clear and accessible prose, Nature's Robots will appeal to general readers with an interest in popular science, in addition to professional scientists and historians of science.
